JP2004522706A5 - - Google Patents

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Publication number
JP2004522706A5
JP2004522706A5 JP2002539332A JP2002539332A JP2004522706A5 JP 2004522706 A5 JP2004522706 A5 JP 2004522706A5 JP 2002539332 A JP2002539332 A JP 2002539332A JP 2002539332 A JP2002539332 A JP 2002539332A JP 2004522706 A5 JP2004522706 A5 JP 2004522706A5
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JP
Japan
Prior art keywords
group
hydrogen
alkyl
substituted
hydroxy
Prior art date
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Application number
JP2002539332A
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English (en)
Japanese (ja)
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JP4340437B2 (ja
JP2004522706A (ja
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Priority claimed from PCT/US2001/045581 external-priority patent/WO2002036573A2/en
Publication of JP2004522706A publication Critical patent/JP2004522706A/ja
Publication of JP2004522706A5 publication Critical patent/JP2004522706A5/ja
Application granted granted Critical
Publication of JP4340437B2 publication Critical patent/JP4340437B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2002539332A 2000-10-31 2001-10-31 ８−カルボキサミド−２，６−メタノ−３−ベンズアゾシン Expired - Lifetime JP4340437B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24443800P 2000-10-31 2000-10-31
PCT/US2001/045581 WO2002036573A2 (en) 2000-10-31 2001-10-31 8- substituted-2, 6-methano-3-benzazocines and 3-substituted morphinanes as opioid receptor binding agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2003422779A Division JP2004137288A (ja) 2000-10-31 2003-12-19 ８−カルボキサミド−２，６−メタノ−３−ベンズアゾシン

Publications (3)

Publication Number Publication Date
JP2004522706A JP2004522706A (ja) 2004-07-29
JP2004522706A5 true JP2004522706A5 (enExample) 2005-02-24
JP4340437B2 JP4340437B2 (ja) 2009-10-07

Family

ID=22922766

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002539332A Expired - Lifetime JP4340437B2 (ja) 2000-10-31 2001-10-31 ８−カルボキサミド−２，６−メタノ−３−ベンズアゾシン
JP2003422779A Pending JP2004137288A (ja) 2000-10-31 2003-12-19 ８−カルボキサミド−２，６−メタノ−３−ベンズアゾシン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2003422779A Pending JP2004137288A (ja) 2000-10-31 2003-12-19 ８−カルボキサミド−２，６−メタノ−３−ベンズアゾシン

Country Status (9)

Country Link
US (9) US6784187B2 (enExample)
EP (3) EP1359146B1 (enExample)
JP (2) JP4340437B2 (enExample)
AT (2) ATE292625T1 (enExample)
AU (2) AU2713502A (enExample)
CA (1) CA2426942C (enExample)
DE (2) DE60109960T2 (enExample)
ES (3) ES2572332T3 (enExample)
WO (1) WO2002036573A2 (enExample)

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US7538110B2 (en) 2005-10-27 2009-05-26 Adolor Corporation Opioid antagonists
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WO2010151317A1 (en) 2009-06-22 2010-12-29 Millennium Pharmaceuticals, Inc. Substituted hydroxamic acids and uses thereof
CA2765678A1 (en) 2009-06-22 2010-12-29 Christopher Blackburn Substituted hydroxamic acids and uses thereof
US10363251B2 (en) 2009-07-16 2019-07-30 Mallinckrodt Llc (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
JP5797655B2 (ja) * 2009-09-18 2015-10-21 アドラー・コーポレーション 消化管障害のためのオピオイド受容体アンタゴニストの使用
AU2010326676B2 (en) 2009-12-04 2013-03-14 Alkermes Pharma Ireland Limited Morphinan derivatives for the treatment of drug overdose
WO2011106632A1 (en) * 2010-02-26 2011-09-01 Millennium Pharmaceuticals, Inc. Substituted hydroxamic acids and uses thereof
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JP5964809B2 (ja) 2010-03-22 2016-08-03 レンセラール ポリテクニック インスティチュート オピオイド受容体リガンドとしてのカルボキサミド基を含有するモルヒネ誘導体
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JP5728084B2 (ja) 2010-07-08 2015-06-03 アルカーメス ファーマ アイルランド リミテッド 置換モルフィナンの合成のための方法
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