JP2005504738A5 - - Google Patents
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- Publication number
- JP2005504738A5 JP2005504738A5 JP2003512224A JP2003512224A JP2005504738A5 JP 2005504738 A5 JP2005504738 A5 JP 2005504738A5 JP 2003512224 A JP2003512224 A JP 2003512224A JP 2003512224 A JP2003512224 A JP 2003512224A JP 2005504738 A5 JP2005504738 A5 JP 2005504738A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- independently
- carbon atoms
- acyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 14
- 125000002252 acyl group Chemical group 0.000 claims 6
- 125000004432 carbon atom Chemical group C* 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 0 Cc(c(N*)c1)c(*)cc1S Chemical compound Cc(c(N*)c1)c(*)cc1S 0.000 description 4
- QUPKCFBHJFNUEW-UHFFFAOYSA-N CCC1=NCCN1 Chemical compound CCC1=NCCN1 QUPKCFBHJFNUEW-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20011507A FI20011507A0 (fi) | 2001-07-10 | 2001-07-10 | Uusia yhdisteitä |
| PCT/FI2002/000621 WO2003006452A1 (en) | 2001-07-10 | 2002-07-10 | New compounds, which are potent inhibitors of na+/ca2+ exchange mechanism and are useful in the treatment of arrhythmias |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005504738A JP2005504738A (ja) | 2005-02-17 |
| JP2005504738A5 true JP2005504738A5 (enExample) | 2008-03-13 |
| JP4113839B2 JP4113839B2 (ja) | 2008-07-09 |
Family
ID=8561628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003512224A Expired - Fee Related JP4113839B2 (ja) | 2001-07-10 | 2002-07-10 | Ｎａ＋／Ｃａ２＋交換機構の強力な阻害剤であり、不整脈の処置において有用である新規化合物 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7425568B2 (enExample) |
| EP (1) | EP1412343B1 (enExample) |
| JP (1) | JP4113839B2 (enExample) |
| KR (1) | KR20040025697A (enExample) |
| CN (1) | CN1281597C (enExample) |
| AR (1) | AR036236A1 (enExample) |
| AT (1) | ATE338038T1 (enExample) |
| AU (1) | AU2002321339B2 (enExample) |
| BR (1) | BR0211070A (enExample) |
| CA (1) | CA2452918C (enExample) |
| DE (1) | DE60214388T2 (enExample) |
| DK (1) | DK1412343T3 (enExample) |
| EA (1) | EA006580B1 (enExample) |
| ES (1) | ES2269746T3 (enExample) |
| FI (1) | FI20011507A0 (enExample) |
| HR (1) | HRP20040133A2 (enExample) |
| HU (1) | HUP0400391A3 (enExample) |
| IL (2) | IL159647A0 (enExample) |
| MX (1) | MXPA04000267A (enExample) |
| NO (1) | NO20035821L (enExample) |
| NZ (1) | NZ530490A (enExample) |
| PL (1) | PL367958A1 (enExample) |
| PT (1) | PT1412343E (enExample) |
| RS (1) | RS50886B (enExample) |
| UA (1) | UA76168C2 (enExample) |
| WO (1) | WO2003006452A1 (enExample) |
| ZA (1) | ZA200400145B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI20030030A0 (fi) * | 2003-01-09 | 2003-01-09 | Orion Corp | Uusia yhdisteitä |
| US8017649B2 (en) | 2005-03-11 | 2011-09-13 | Howard Florey Institute Of Experimental Physiology And Medicine | Flavonoid compounds and uses thereof |
| JP5941637B2 (ja) * | 2011-09-12 | 2016-06-29 | サノフイ | 置換２−（クロマン−６−イルオキシ）−チアゾール及び医薬としてのその使用 |
| EP2567958B1 (en) | 2011-09-12 | 2014-10-29 | Sanofi | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
| CA2846347C (en) * | 2011-09-12 | 2019-05-21 | Sanofi | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
| US8912224B2 (en) | 2011-09-12 | 2014-12-16 | Sanofi | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
| CN102993195B (zh) * | 2011-09-14 | 2017-05-17 | 赛诺菲 | 取代的2‑(色满‑6‑基氧基)噻唑及其作为药物的用途 |
| CN103030646B (zh) * | 2011-09-29 | 2016-08-24 | 上海恒瑞医药有限公司 | 苯并二氧六环类衍生物、其制备方法及其在医药上的应用 |
| TWI633095B (zh) * | 2013-03-08 | 2018-08-21 | 賽諾菲公司 | 經取代－６－基氧基－環烷類及其作為醫藥品之用途 |
| GB201416186D0 (en) | 2014-09-12 | 2014-10-29 | Redx Pharma Ltd | Compounds |
| WO2019175464A1 (en) | 2018-03-14 | 2019-09-19 | Orion Corporation | Compounds useful as inhibitors of sodium-calcium exchanger (ncx) |
| US11858930B2 (en) | 2020-07-28 | 2024-01-02 | Jazz Pharmaceuticals Ireland Limited | Fused bicyclic RAF inhibitors and methods for use thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2820817A (en) * | 1954-02-04 | 1958-01-21 | Mcneilab Inc | Oxygenated indan compounds and method of making the same |
| US3862232A (en) * | 1963-07-03 | 1975-01-21 | Upjohn Co | 1-(p-hydroxyphenyl)-2-phenyl-6-(2-diethylaminoethoxy)-3,4-dihydronaphthalene and the salts thereof |
| BE650081A (enExample) | 1963-07-03 | |||
| GB1154119A (en) | 1968-05-20 | 1969-06-04 | Merck Ag E | 3-Alkyl-Flavanones |
| FR2733685B1 (fr) | 1995-05-05 | 1997-05-30 | Adir | Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant |
| JPH0967336A (ja) | 1995-09-04 | 1997-03-11 | Kanebo Ltd | 新規なイソチオウレア誘導体 |
| AU726239B2 (en) | 1997-03-27 | 2000-11-02 | Taisho Pharmaceutical Co., Ltd. | 2-phenoxyaniline derivatives |
| JPH1149752A (ja) | 1997-08-05 | 1999-02-23 | Taisho Pharmaceut Co Ltd | フェノキシピリジン誘導体 |
| DE19742508A1 (de) | 1997-09-26 | 1999-04-01 | Hoechst Marion Roussel De Gmbh | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
| US6162832A (en) | 1997-10-20 | 2000-12-19 | Taisho Pharmaceutical Co., Inc. | 2-Phenoxyaniline derivatives |
| JPH11302235A (ja) | 1998-04-15 | 1999-11-02 | Taisho Pharmaceut Co Ltd | フェノキシアルキルアミン誘導体 |
| AU4360200A (en) | 1999-04-23 | 2000-11-10 | Bristol-Myers Squibb Company | Bicyclic acyl guanidine sodium/proton exchange inhibitors and method |
| US6589983B1 (en) | 1999-09-17 | 2003-07-08 | Nissan Chemical Industries, Ltd. | Benzopyran derivative |
| FI20030030A0 (fi) | 2003-01-09 | 2003-01-09 | Orion Corp | Uusia yhdisteitä |
-
2001
- 2001-07-10 FI FI20011507A patent/FI20011507A0/fi unknown
-
2002
- 2002-07-10 EP EP02755036A patent/EP1412343B1/en not_active Expired - Lifetime
- 2002-07-10 MX MXPA04000267A patent/MXPA04000267A/es active IP Right Grant
- 2002-07-10 EA EA200400161A patent/EA006580B1/ru not_active IP Right Cessation
- 2002-07-10 IL IL15964702A patent/IL159647A0/xx active IP Right Grant
- 2002-07-10 DK DK02755036T patent/DK1412343T3/da active
- 2002-07-10 ES ES02755036T patent/ES2269746T3/es not_active Expired - Lifetime
- 2002-07-10 NZ NZ530490A patent/NZ530490A/en not_active IP Right Cessation
- 2002-07-10 CN CNB028138635A patent/CN1281597C/zh not_active Expired - Fee Related
- 2002-07-10 US US10/482,396 patent/US7425568B2/en not_active Expired - Fee Related
- 2002-07-10 KR KR10-2004-7000332A patent/KR20040025697A/ko not_active Ceased
- 2002-07-10 HR HR20040133A patent/HRP20040133A2/hr not_active Application Discontinuation
- 2002-07-10 BR BR0211070-9A patent/BR0211070A/pt not_active IP Right Cessation
- 2002-07-10 DE DE60214388T patent/DE60214388T2/de not_active Expired - Fee Related
- 2002-07-10 AR ARP020102586A patent/AR036236A1/es unknown
- 2002-07-10 JP JP2003512224A patent/JP4113839B2/ja not_active Expired - Fee Related
- 2002-07-10 PT PT02755036T patent/PT1412343E/pt unknown
- 2002-07-10 WO PCT/FI2002/000621 patent/WO2003006452A1/en not_active Ceased
- 2002-07-10 RS YUP-6/04A patent/RS50886B/sr unknown
- 2002-07-10 PL PL02367958A patent/PL367958A1/xx unknown
- 2002-07-10 HU HU0400391A patent/HUP0400391A3/hu unknown
- 2002-07-10 AT AT02755036T patent/ATE338038T1/de not_active IP Right Cessation
- 2002-07-10 CA CA2452918A patent/CA2452918C/en not_active Expired - Fee Related
- 2002-07-10 AU AU2002321339A patent/AU2002321339B2/en not_active Ceased
- 2002-10-07 UA UA2004020928A patent/UA76168C2/uk unknown
-
2003
- 2003-12-23 NO NO20035821A patent/NO20035821L/no not_active Application Discontinuation
- 2003-12-30 IL IL159647A patent/IL159647A/en not_active IP Right Cessation
-
2004
- 2004-01-08 ZA ZA200400145A patent/ZA200400145B/en unknown
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