JP2007507472A5 - - Google Patents
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- Publication number
- JP2007507472A5 JP2007507472A5 JP2006530316A JP2006530316A JP2007507472A5 JP 2007507472 A5 JP2007507472 A5 JP 2007507472A5 JP 2006530316 A JP2006530316 A JP 2006530316A JP 2006530316 A JP2006530316 A JP 2006530316A JP 2007507472 A5 JP2007507472 A5 JP 2007507472A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- following structure
- pharmaceutically acceptable
- following
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 18
- 150000003839 salts Chemical class 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 108010064556 somatostatin receptor subtype-4 Proteins 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 0 BC(C(NC(C(*)c1ccccc1)C(N)=O)=O)NS(c1ccc(*)c2ccccc12)(=O)=O Chemical compound BC(C(NC(C(*)c1ccccc1)C(N)=O)=O)NS(c1ccc(*)c2ccccc12)(=O)=O 0.000 description 1
- SULXMQNZKSOWDF-XALFVWFESA-N C/C=C\C=C/C(C1c2ccccc2)=[O]=C([C@H](CCCNC(N)=N)NS(c2c(cccc3)c3c(C)cc2)(=O)=O)N[C@@H]1C(N)=O Chemical compound C/C=C\C=C/C(C1c2ccccc2)=[O]=C([C@H](CCCNC(N)=N)NS(c2c(cccc3)c3c(C)cc2)(=O)=O)N[C@@H]1C(N)=O SULXMQNZKSOWDF-XALFVWFESA-N 0.000 description 1
- LEMHWIFLIGSCTG-KEKNWZKVSA-N CCc(cc1)c(cccc2)c2c1S(NC(CCN)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O Chemical compound CCc(cc1)c(cccc2)c2c1S(NC(CCN)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O LEMHWIFLIGSCTG-KEKNWZKVSA-N 0.000 description 1
- YEWSSTXDDLMJSR-UHFFFAOYSA-N Cc(cc1)c(cccc2)c2c1S(NC(C1CCNCC1)C(NC(Cc1ccccc1)C(N)=O)=O)(=O)=O Chemical compound Cc(cc1)c(cccc2)c2c1S(NC(C1CCNCC1)C(NC(Cc1ccccc1)C(N)=O)=O)(=O)=O YEWSSTXDDLMJSR-UHFFFAOYSA-N 0.000 description 1
- VTNCZBXJSGKDLS-LBAQZLPGSA-N Cc(cc1)c(cccc2)c2c1S(NC(CCN)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O Chemical compound Cc(cc1)c(cccc2)c2c1S(NC(CCN)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O VTNCZBXJSGKDLS-LBAQZLPGSA-N 0.000 description 1
- KMHKFNAEOVWGQJ-VXKWHMMOSA-N Cc(cc1)c(cccc2)c2c1S(N[C@@H](CCCN)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O Chemical compound Cc(cc1)c(cccc2)c2c1S(N[C@@H](CCCN)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O KMHKFNAEOVWGQJ-VXKWHMMOSA-N 0.000 description 1
- SCIJPEKSIODKGC-VXKWHMMOSA-N Cc(cc1)c(cccc2)c2c1S(N[C@@H](CCCNC(N)=N)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O Chemical compound Cc(cc1)c(cccc2)c2c1S(N[C@@H](CCCNC(N)=N)C(N[C@@H](Cc1ccccc1)C(N)=O)=O)(=O)=O SCIJPEKSIODKGC-VXKWHMMOSA-N 0.000 description 1
- SOGXYKHOJAZGHZ-PMACEKPBSA-N NCC[C@@H](C(N[C@@H](Cc1ccccc1)C(N)=O)=O)NS(c1c(cccc2)c2ccc1)(=O)=O Chemical compound NCC[C@@H](C(N[C@@H](Cc1ccccc1)C(N)=O)=O)NS(c1c(cccc2)c2ccc1)(=O)=O SOGXYKHOJAZGHZ-PMACEKPBSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50827003P | 2003-10-06 | 2003-10-06 | |
| FI20031455A FI20031455A0 (fi) | 2003-10-06 | 2003-10-06 | Sulfonyyliamino-peptidomimeettejä, jotka ovat aktiivisia somatostatiinireseptorialatyyppien 4 (SSTR4) ja 1 (SSTR1) suhteen |
| PCT/FI2004/000583 WO2005033124A1 (en) | 2003-10-06 | 2004-10-05 | Sulfonylamino-peptidomimetics active on the somatostatin receptor subtypes 4 (sstr4) and 1 (sstr1) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007507472A JP2007507472A (ja) | 2007-03-29 |
| JP2007507472A5 true JP2007507472A5 (enExample) | 2007-11-22 |
Family
ID=29225904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006530316A Pending JP2007507472A (ja) | 2003-10-06 | 2004-10-05 | ソマトスタチン受容体サブタイプ４（ｓｓｔｒ４）及び１（ｓｓｔｒ１）に作用するスルホニルアミノ−ペプチド模倣薬 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070129313A1 (enExample) |
| EP (1) | EP1678196B1 (enExample) |
| JP (1) | JP2007507472A (enExample) |
| AT (1) | ATE404580T1 (enExample) |
| FI (1) | FI20031455A0 (enExample) |
| WO (1) | WO2005033124A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI20031454A0 (fi) * | 2003-10-06 | 2003-10-06 | Juvantia Pharma Ltd Oy | Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja |
| US20100004339A1 (en) * | 2003-10-06 | 2010-01-07 | Oy Juvantia Pharma Ltd. | Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists |
| WO2005082844A1 (en) * | 2004-02-27 | 2005-09-09 | Oy Juvantia Pharma Ltd | Treatment of diseases by using a somatostatin receptor agonist |
| WO2005082845A1 (en) * | 2004-02-27 | 2005-09-09 | Oy Juvantia Pharma Ltd | Novel therapies with somatostatin receptor agonists |
| JP2008540618A (ja) * | 2005-05-18 | 2008-11-20 | ブルスター，ジークフリート | ソマトスタチン受容体サブタイプ１及び／又は４に選択的なペプチド模倣薬 |
| EP3634406B1 (en) | 2017-05-12 | 2023-09-06 | Board of Trustees of The Southern Illinois University on behalf of Southern Illinois University Edwardsville | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof |
| US11912687B2 (en) | 2017-05-12 | 2024-02-27 | Board of Trustees of the Southern Illinois University | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof |
| JP7099717B2 (ja) * | 2019-09-30 | 2022-07-12 | 株式会社理研バイオ | ソマトスタチン受容体 |
| AR121683A1 (es) * | 2020-03-31 | 2022-06-29 | Takeda Pharmaceuticals Co | Derivados de n-heteroarilalquil-2-(heterociclil y heterociclilmetil)acetamida como agonistas de sstr4 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040007565A (ko) * | 2001-05-15 | 2004-01-24 | 다이쇼 세이야꾸 가부시끼가이샤 | 아르기닌 유도체 |
| WO2003026657A1 (en) * | 2001-09-24 | 2003-04-03 | Synaptic Pharmaceutical Corporation | Compounds for the treatment of pain |
| WO2003026575A2 (en) * | 2001-09-24 | 2003-04-03 | Synaptic Pharmaceutical Corporation | Molecules specific for npff receptors and uses thereof |
| JP2004155695A (ja) * | 2002-11-06 | 2004-06-03 | Taisho Pharmaceut Co Ltd | Ｍｃ４受容体に対するリガンド |
| FI20031454A0 (fi) * | 2003-10-06 | 2003-10-06 | Juvantia Pharma Ltd Oy | Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja |
-
2003
- 2003-10-06 FI FI20031455A patent/FI20031455A0/fi not_active Application Discontinuation
-
2004
- 2004-10-05 EP EP04767097A patent/EP1678196B1/en not_active Expired - Lifetime
- 2004-10-05 AT AT04767097T patent/ATE404580T1/de not_active IP Right Cessation
- 2004-10-05 US US10/574,905 patent/US20070129313A1/en not_active Abandoned
- 2004-10-05 WO PCT/FI2004/000583 patent/WO2005033124A1/en not_active Ceased
- 2004-10-05 JP JP2006530316A patent/JP2007507472A/ja active Pending