JP2004517098A5 - - Google Patents
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- Publication number
- JP2004517098A5 JP2004517098A5 JP2002551528A JP2002551528A JP2004517098A5 JP 2004517098 A5 JP2004517098 A5 JP 2004517098A5 JP 2002551528 A JP2002551528 A JP 2002551528A JP 2002551528 A JP2002551528 A JP 2002551528A JP 2004517098 A5 JP2004517098 A5 JP 2004517098A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- solvate
- salt
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0031315.5A GB0031315D0 (en) | 2000-12-21 | 2000-12-21 | Indole derivatives |
| PCT/GB2001/005701 WO2002050031A1 (en) | 2000-12-21 | 2001-12-20 | Indole derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004517098A JP2004517098A (ja) | 2004-06-10 |
| JP2004517098A5 true JP2004517098A5 (https=) | 2005-12-22 |
| JP4460830B2 JP4460830B2 (ja) | 2010-05-12 |
Family
ID=9905643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002551528A Expired - Fee Related JP4460830B2 (ja) | 2000-12-21 | 2001-12-20 | インドール誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7288564B2 (https=) |
| EP (1) | EP1343757B1 (https=) |
| JP (1) | JP4460830B2 (https=) |
| AT (1) | ATE353875T1 (https=) |
| AU (1) | AU2002217286A1 (https=) |
| DE (1) | DE60126652T2 (https=) |
| ES (1) | ES2282195T3 (https=) |
| GB (1) | GB0031315D0 (https=) |
| WO (1) | WO2002050031A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HN2001000224A (es) | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
| SE0301446D0 (sv) | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
| SE0402284D0 (sv) * | 2004-09-21 | 2004-09-21 | Astrazeneca Ab | New heterocyclic amides |
| JP2008518957A (ja) * | 2004-11-04 | 2008-06-05 | メルク エンド カムパニー インコーポレーテッド | ナイアシン受容体作動薬、そのような化合物を含んでいる組成物及び治療方法 |
| WO2007044724A2 (en) * | 2005-10-06 | 2007-04-19 | Exelixis, Inc. | Aminopyrimidine, aminopyridine and aniline derivatives inhibitors of pim-i and/or pim-3 |
| TW200736227A (en) * | 2005-12-23 | 2007-10-01 | Astrazeneca Ab | New compounds III |
| UY30121A1 (es) | 2006-02-03 | 2007-08-31 | Glaxo Group Ltd | Nuevos compuestos |
| ES2392192T3 (es) * | 2006-04-24 | 2012-12-05 | Merck Canada Inc. | Derivados de indol amida como antagonistas del receptor EP4 |
| TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
| US20100074896A1 (en) * | 2006-11-30 | 2010-03-25 | The Johns Hopkins University | Antagonists of pge2 ep3 receptors |
| AU2007331471C1 (en) | 2006-12-15 | 2013-07-25 | Glaxo Group Limited | Benzamide derivatives as EP4 receptor agonists |
| GB0701970D0 (en) * | 2007-02-01 | 2007-03-14 | Wilson Stuart | Treatment of protein aggregation diseases |
| JP5408434B2 (ja) * | 2007-07-03 | 2014-02-05 | アステラス製薬株式会社 | アミド化合物 |
| GB0721611D0 (en) | 2007-11-02 | 2007-12-12 | Glaxo Group Ltd | Novel compounds |
| EP2565191B1 (en) * | 2008-05-14 | 2014-10-08 | Astellas Pharma Inc. | 4-(Indol-7-ylcarbonylaminomethyl)cyclohexanecarboxylic acid derivatives as EP4 receptor antagonists useful for the treatment of chronic renal failure or diabetic nephropathy |
| EP2392323A4 (en) | 2009-01-30 | 2012-09-26 | Univ Kyoto | INHIBITOR OF PROSTATE CANCER PROGRESSION AND METHOD OF INHIBITING PROGRESSION |
| CA2777782C (en) * | 2009-10-15 | 2016-06-28 | Children's Medical Center Corporation | Sepiapterin reductase inhibitors for the treatment of pain |
| US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| DK2970265T3 (en) * | 2013-03-15 | 2018-10-01 | Plexxikon Inc | HETEROCYCLIC COMPOUNDS AND APPLICATIONS THEREOF |
| US20140303121A1 (en) | 2013-03-15 | 2014-10-09 | Plexxikon Inc. | Heterocyclic compounds and uses thereof |
| EP2970177A1 (en) | 2013-03-15 | 2016-01-20 | Pfizer Inc. | Indole compounds that activate ampk |
| JP7211358B2 (ja) * | 2017-05-22 | 2023-01-24 | 小野薬品工業株式会社 | Ｅｐ４アンタゴニスト |
| US10717735B2 (en) | 2017-10-13 | 2020-07-21 | Plexxikon Inc. | Solid forms of a compound for modulating kinases |
| US20230390303A1 (en) | 2020-11-13 | 2023-12-07 | Ono Pharmaceutical Co., Ltd. | Cancer treatment by combination of ep4 antagonist and immune checkpoint inhibitor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4251446A (en) * | 1977-03-01 | 1981-02-17 | Sterling Drug Inc. | Phthalide compounds, processes and marking systems |
| US4322352A (en) * | 1979-04-04 | 1982-03-30 | Sterling Drug Inc. | Indolyl phthalide compounds |
| JPS62138469A (ja) * | 1985-12-11 | 1987-06-22 | Yoshitomi Pharmaceut Ind Ltd | インド−ル誘導体 |
| US5075313A (en) * | 1990-09-13 | 1991-12-24 | Eli Lilly And Company | 3-aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof |
| GB9022785D0 (en) * | 1990-10-19 | 1990-12-05 | Merck Sharp & Dohme | Therapeutic agents |
| WO1997021435A1 (en) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| JP2000516958A (ja) * | 1996-08-26 | 2000-12-19 | ジェネティックス・インスチチュート・インコーポレーテッド | ホスホリパーゼ酵素の阻害剤 |
| JPH1171336A (ja) * | 1997-06-25 | 1999-03-16 | Mitsubishi Chem Corp | アミド誘導体 |
| WO2000006550A1 (en) * | 1998-07-31 | 2000-02-10 | Nippon Soda Co., Ltd. | Phenylazole compounds, process for producing the same and drugs for hyperlipemia |
| US6437146B1 (en) * | 1998-09-25 | 2002-08-20 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compounds as prostaglandin e2 agonists or antagonists |
| JP2002527393A (ja) * | 1998-10-15 | 2002-08-27 | メルク エンド カムパニー インコーポレーテッド | 骨吸収阻害方法 |
| GB9902455D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| EP1312601A4 (en) * | 2000-08-22 | 2005-09-21 | Ono Pharmaceutical Co | CARBOXYLENE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICAMENTS CONTAINING THEM AS AN ACTIVE SUBSTANCE |
| JP4212358B2 (ja) * | 2000-12-28 | 2009-01-21 | 第一三共株式会社 | Ｖｌａ−４阻害薬 |
-
2000
- 2000-12-21 GB GBGB0031315.5A patent/GB0031315D0/en not_active Ceased
-
2001
- 2001-12-20 JP JP2002551528A patent/JP4460830B2/ja not_active Expired - Fee Related
- 2001-12-20 WO PCT/GB2001/005701 patent/WO2002050031A1/en not_active Ceased
- 2001-12-20 DE DE60126652T patent/DE60126652T2/de not_active Expired - Lifetime
- 2001-12-20 AT AT01271354T patent/ATE353875T1/de not_active IP Right Cessation
- 2001-12-20 ES ES01271354T patent/ES2282195T3/es not_active Expired - Lifetime
- 2001-12-20 AU AU2002217286A patent/AU2002217286A1/en not_active Abandoned
- 2001-12-20 EP EP01271354A patent/EP1343757B1/en not_active Expired - Lifetime
- 2001-12-20 US US10/450,894 patent/US7288564B2/en not_active Expired - Fee Related
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