JP2004517098A5 - - Google Patents

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Publication number
JP2004517098A5
JP2004517098A5 JP2002551528A JP2002551528A JP2004517098A5 JP 2004517098 A5 JP2004517098 A5 JP 2004517098A5 JP 2002551528 A JP2002551528 A JP 2002551528A JP 2002551528 A JP2002551528 A JP 2002551528A JP 2004517098 A5 JP2004517098 A5 JP 2004517098A5
Authority
JP
Japan
Prior art keywords
alkyl
formula
solvate
salt
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002551528A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004517098A (ja
JP4460830B2 (ja
Filing date
Publication date
Priority claimed from GBGB0031315.5A external-priority patent/GB0031315D0/en
Application filed filed Critical
Publication of JP2004517098A publication Critical patent/JP2004517098A/ja
Publication of JP2004517098A5 publication Critical patent/JP2004517098A5/ja
Application granted granted Critical
Publication of JP4460830B2 publication Critical patent/JP4460830B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2002551528A 2000-12-21 2001-12-20 インドール誘導体 Expired - Fee Related JP4460830B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0031315.5A GB0031315D0 (en) 2000-12-21 2000-12-21 Indole derivatives
PCT/GB2001/005701 WO2002050031A1 (en) 2000-12-21 2001-12-20 Indole derivatives

Publications (3)

Publication Number Publication Date
JP2004517098A JP2004517098A (ja) 2004-06-10
JP2004517098A5 true JP2004517098A5 (enExample) 2005-12-22
JP4460830B2 JP4460830B2 (ja) 2010-05-12

Family

ID=9905643

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002551528A Expired - Fee Related JP4460830B2 (ja) 2000-12-21 2001-12-20 インドール誘導体

Country Status (9)

Country Link
US (1) US7288564B2 (enExample)
EP (1) EP1343757B1 (enExample)
JP (1) JP4460830B2 (enExample)
AT (1) ATE353875T1 (enExample)
AU (1) AU2002217286A1 (enExample)
DE (1) DE60126652T2 (enExample)
ES (1) ES2282195T3 (enExample)
GB (1) GB0031315D0 (enExample)
WO (1) WO2002050031A1 (enExample)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
HN2001000224A (es) 2000-10-19 2002-06-13 Pfizer Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos.
SE0301446D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab New Compounds
SE0402284D0 (sv) * 2004-09-21 2004-09-21 Astrazeneca Ab New heterocyclic amides
JP2008518957A (ja) * 2004-11-04 2008-06-05 メルク エンド カムパニー インコーポレーテッド ナイアシン受容体作動薬、そのような化合物を含んでいる組成物及び治療方法
CA2623759A1 (en) 2005-10-06 2007-04-19 Exelixis, Inc. Pyridopyrimidinone inhibitors of pim 1 and/or pim-3
UY30048A1 (es) 2005-12-23 2007-07-31 Astrazeneca Ab Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones
UY30121A1 (es) 2006-02-03 2007-08-31 Glaxo Group Ltd Nuevos compuestos
JP5244091B2 (ja) * 2006-04-24 2013-07-24 メルク カナダ インコーポレイテッド Ｅｐ４受容体アンタゴニストとしてのインドールアミド誘導体
TWI433839B (zh) * 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290
US20100074896A1 (en) * 2006-11-30 2010-03-25 The Johns Hopkins University Antagonists of pge2 ep3 receptors
JP5069752B2 (ja) 2006-12-15 2012-11-07 グラクソ グループ リミテッド Ｅｐ４受容体アゴニストとしてのベンズアミド誘導体
GB0701970D0 (en) * 2007-02-01 2007-03-14 Wilson Stuart Treatment of protein aggregation diseases
EP2172447A4 (en) * 2007-07-03 2011-08-24 Astellas Pharma Inc amide
GB0721611D0 (en) 2007-11-02 2007-12-12 Glaxo Group Ltd Novel compounds
ES2518919T3 (es) * 2008-05-14 2014-11-05 Astellas Pharma Inc. Derivados del ácido 4-(Indol-7-ilcarbonilaminometil)ciclohexanocarboxílico como antagonistas del receptor EP4 útiles para el tratamiento de la insuficiencia renal crónica o la nefropatía diabética
WO2010087425A1 (ja) 2009-01-30 2010-08-05 国立大学法人京都大学 前立腺癌の進行抑制剤および進行抑制方法
AU2010306750B2 (en) * 2009-10-15 2014-11-13 Children's Medical Center Corporation Sepiapterin reductase inhibitors for the treatment of pain
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
US20140303121A1 (en) 2013-03-15 2014-10-09 Plexxikon Inc. Heterocyclic compounds and uses thereof
CN105073747B (zh) * 2013-03-15 2017-06-06 普莱希科公司 杂环化合物及其应用
JP6064062B2 (ja) 2013-03-15 2017-01-18 ファイザー・インク Ａｍｐｋを活性化させるインダゾール化合物
JP7211358B2 (ja) * 2017-05-22 2023-01-24 小野薬品工業株式会社 Ｅｐ４アンタゴニスト
US10717735B2 (en) 2017-10-13 2020-07-21 Plexxikon Inc. Solid forms of a compound for modulating kinases
JP7816164B2 (ja) 2020-11-13 2026-02-18 小野薬品工業株式会社 Ｅｐ４拮抗薬と免疫チェックポイント阻害物質との併用によるがん治療

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4251446A (en) * 1977-03-01 1981-02-17 Sterling Drug Inc. Phthalide compounds, processes and marking systems
US4322352A (en) * 1979-04-04 1982-03-30 Sterling Drug Inc. Indolyl phthalide compounds
JPS62138469A (ja) * 1985-12-11 1987-06-22 Yoshitomi Pharmaceut Ind Ltd インド−ル誘導体
US5075313A (en) * 1990-09-13 1991-12-24 Eli Lilly And Company 3-aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof
GB9022785D0 (en) * 1990-10-19 1990-12-05 Merck Sharp & Dohme Therapeutic agents
WO1997021435A1 (en) * 1995-12-14 1997-06-19 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP2000516958A (ja) * 1996-08-26 2000-12-19 ジェネティックス・インスチチュート・インコーポレーテッド ホスホリパーゼ酵素の阻害剤
JPH1171336A (ja) * 1997-06-25 1999-03-16 Mitsubishi Chem Corp アミド誘導体
CN1131217C (zh) * 1998-07-31 2003-12-17 日本曹达株式会社 苯基吡咯化合物和其制备方法及抗高血脂药
US6437146B1 (en) * 1998-09-25 2002-08-20 Fujisawa Pharmaceutical Co., Ltd. Oxazole compounds as prostaglandin e2 agonists or antagonists
CA2346038A1 (en) 1998-10-15 2000-04-20 Merck & Co., Inc. Methods for inhibiting bone resorption
GB9902455D0 (en) * 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
WO2002016311A1 (en) * 2000-08-22 2002-02-28 Ono Pharmaceutical Co., Ltd. Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient
CA2430978C (en) * 2000-12-28 2012-05-15 Daiichi Pharmaceutical Co., Ltd. Vla-4 inhibitors

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