JP2004515532A5 - - Google Patents
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- JP2004515532A5 JP2004515532A5 JP2002549265A JP2002549265A JP2004515532A5 JP 2004515532 A5 JP2004515532 A5 JP 2004515532A5 JP 2002549265 A JP2002549265 A JP 2002549265A JP 2002549265 A JP2002549265 A JP 2002549265A JP 2004515532 A5 JP2004515532 A5 JP 2004515532A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- bile
- composition according
- acid
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 239000003613 bile acid Substances 0.000 claims 8
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 claims 4
- 239000003833 bile salt Substances 0.000 claims 4
- 229940093761 bile salts Drugs 0.000 claims 4
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims 2
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 claims 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 1
- 244000192528 Chrysanthemum parthenium Species 0.000 claims 1
- 235000011201 Ginkgo Nutrition 0.000 claims 1
- 235000008100 Ginkgo biloba Nutrition 0.000 claims 1
- 244000194101 Ginkgo biloba Species 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- 241000546188 Hypericum Species 0.000 claims 1
- 235000017309 Hypericum perforatum Nutrition 0.000 claims 1
- 235000017945 Matricaria Nutrition 0.000 claims 1
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims 1
- 244000062730 Melissa officinalis Species 0.000 claims 1
- 235000010654 Melissa officinalis Nutrition 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 240000008440 Passiflora incarnata Species 0.000 claims 1
- 235000011922 Passiflora incarnata Nutrition 0.000 claims 1
- 240000007164 Salvia officinalis Species 0.000 claims 1
- 235000002912 Salvia officinalis Nutrition 0.000 claims 1
- 235000012511 Vaccinium Nutrition 0.000 claims 1
- 241000736767 Vaccinium Species 0.000 claims 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims 1
- 229930003316 Vitamin D Natural products 0.000 claims 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 229930003448 Vitamin K Natural products 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 1
- 229940114079 arachidonic acid Drugs 0.000 claims 1
- 235000021342 arachidonic acid Nutrition 0.000 claims 1
- 210000000941 bile Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 230000021615 conjugation Effects 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 230000029087 digestion Effects 0.000 claims 1
- 210000002249 digestive system Anatomy 0.000 claims 1
- 230000006806 disease prevention Effects 0.000 claims 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 1
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 1
- 239000000284 extract Substances 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 230000001771 impaired effect Effects 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 229960004488 linolenic acid Drugs 0.000 claims 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 claims 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims 1
- 235000002020 sage Nutrition 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 229960003080 taurine Drugs 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 239000011719 vitamin A Substances 0.000 claims 1
- 235000019155 vitamin A Nutrition 0.000 claims 1
- 239000011710 vitamin D Substances 0.000 claims 1
- 235000019166 vitamin D Nutrition 0.000 claims 1
- 150000003710 vitamin D derivatives Chemical class 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 235000019168 vitamin K Nutrition 0.000 claims 1
- 239000011712 vitamin K Substances 0.000 claims 1
- 150000003721 vitamin K derivatives Chemical class 0.000 claims 1
- 229940045997 vitamin a Drugs 0.000 claims 1
- 229940046008 vitamin d Drugs 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
- 229940046010 vitamin k Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0004919A HU0004919D0 (https=) | 2000-12-13 | 2000-12-13 | |
| HU0105291A HUP0105291A2 (en) | 2001-12-11 | 2001-12-11 | Pharmaceutical compositions for the treatment of indigestion and related diseases |
| PCT/HU2001/000123 WO2002047694A1 (en) | 2000-12-13 | 2001-12-13 | Pharmaceutical compositions for treatment of digestive disorders and associated diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004515532A JP2004515532A (ja) | 2004-05-27 |
| JP2004515532A5 true JP2004515532A5 (https=) | 2005-04-21 |
Family
ID=89979981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002549265A Pending JP2004515532A (ja) | 2000-12-13 | 2001-12-13 | 消化障害及び関連する疾患を治療するための医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040038952A1 (https=) |
| EP (1) | EP1408982A1 (https=) |
| JP (1) | JP2004515532A (https=) |
| AU (1) | AU2002216301A1 (https=) |
| CA (1) | CA2445091A1 (https=) |
| WO (1) | WO2002047694A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10315024A1 (de) * | 2003-04-02 | 2004-10-14 | Bioplanta Arzneimittel Gmbh | Wirkstoffkombination aus ω3-fettsäurehaltigen Ölen mit isoprenoidhaltigen Pflanzenextrakten und deren Verwendung |
| US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
| MXPA06013437A (es) * | 2004-05-19 | 2007-03-23 | Los Angeles Biomed Res Inst | Uso de un detergente para la eliminacion no quirurgica de grasa. |
| US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
| JP2008530100A (ja) * | 2005-02-10 | 2008-08-07 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 視覚障害の治療方法 |
| DE202005005094U1 (de) * | 2005-03-31 | 2005-07-28 | Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh | Ophthalmische Zusammensetzung |
| CN101366451B (zh) * | 2008-08-28 | 2011-05-11 | 成都思来生物科技有限公司 | 一种提高油脂消化利用率的饲料添加剂及其制备方法 |
| US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| MX363465B (es) | 2011-02-18 | 2019-03-25 | Kythera Biopharmaceuticals Inc | Tratamiento de la grasa submental. |
| US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
| US20130210907A1 (en) * | 2012-02-15 | 2013-08-15 | Hong Kong Baptist University | Method for preventing or treating enterochromaffin cell hyperplasia-related diseases by quercetin administration |
| CN105326808B (zh) * | 2013-12-02 | 2018-05-15 | 北京三泉医药技术有限公司 | 用于清热化痰解毒的胶囊剂 |
| CN107296822A (zh) * | 2017-03-10 | 2017-10-27 | 广州致评医药科技有限公司 | 一种中药难溶性有效成分的固体分散体及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945409A (en) * | 1995-03-10 | 1999-08-31 | Wilson T. Crandall | Topical moisturizing composition and method |
| CH693625A5 (it) * | 1999-02-18 | 2003-11-28 | Inpharma Sa | Composizioni farmaceutiche contenenti composti ad attività promotrice di assorbimento di principi attivi. |
-
2001
- 2001-12-13 AU AU2002216301A patent/AU2002216301A1/en not_active Abandoned
- 2001-12-13 EP EP01270334A patent/EP1408982A1/en not_active Withdrawn
- 2001-12-13 JP JP2002549265A patent/JP2004515532A/ja active Pending
- 2001-12-13 WO PCT/HU2001/000123 patent/WO2002047694A1/en not_active Ceased
- 2001-12-13 CA CA002445091A patent/CA2445091A1/en not_active Abandoned
- 2001-12-13 US US10/450,359 patent/US20040038952A1/en not_active Abandoned
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