JP2004514150A - 蛍光媒介式分子断層撮影法 - Google Patents

蛍光媒介式分子断層撮影法 Download PDF

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Publication number
JP2004514150A
JP2004514150A JP2002543944A JP2002543944A JP2004514150A JP 2004514150 A JP2004514150 A JP 2004514150A JP 2002543944 A JP2002543944 A JP 2002543944A JP 2002543944 A JP2002543944 A JP 2002543944A JP 2004514150 A JP2004514150 A JP 2004514150A
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light
signal
measurement result
array
fluorescence
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Pending
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JP2002543944A
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Japanese (ja)
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JP2004514150A5 (enExample
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ニツィアクリストス バシリス
ワイスレーダー ラルフ
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General Hospital Corp
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General Hospital Corp
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Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of JP2004514150A publication Critical patent/JP2004514150A/ja
Publication of JP2004514150A5 publication Critical patent/JP2004514150A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/12Macromolecular compounds
    • A61K49/126Linear polymers, e.g. dextran, inulin, PEG
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4795Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40Animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0223Operational features of calibration, e.g. protocols for calibrating sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/508Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for non-human patients
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2002543944A 2000-11-27 2001-11-27 蛍光媒介式分子断層撮影法 Pending JP2004514150A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/723,033 US6615063B1 (en) 2000-11-27 2000-11-27 Fluorescence-mediated molecular tomography
PCT/US2001/044764 WO2002041760A2 (en) 2000-11-27 2001-11-27 Fluorescence-mediated molecular tomography

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008004715A Division JP5134977B2 (ja) 2000-11-27 2008-01-11 蛍光媒介式分子断層撮影法

Publications (2)

Publication Number Publication Date
JP2004514150A true JP2004514150A (ja) 2004-05-13
JP2004514150A5 JP2004514150A5 (enExample) 2005-09-02

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Family Applications (2)

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JP2002543944A Pending JP2004514150A (ja) 2000-11-27 2001-11-27 蛍光媒介式分子断層撮影法
JP2008004715A Expired - Lifetime JP5134977B2 (ja) 2000-11-27 2008-01-11 蛍光媒介式分子断層撮影法

Family Applications After (1)

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Country Status (8)

Country Link
US (1) US6615063B1 (enExample)
EP (3) EP2319399B1 (enExample)
JP (2) JP2004514150A (enExample)
AT (2) ATE420592T1 (enExample)
AU (2) AU2867302A (enExample)
CA (2) CA2428462C (enExample)
DE (1) DE60137453D1 (enExample)
WO (1) WO2002041760A2 (enExample)

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JP2007222669A (ja) * 2003-10-28 2007-09-06 Veralight Inc 組織の蛍光発光を用いた糖化最終産物または疾病状態の尺度の決定
JPWO2008010604A1 (ja) * 2006-07-19 2009-12-17 学校法人北里研究所 血管撮影装置及び血管分布解析システム
JP2010509976A (ja) * 2006-11-21 2010-04-02 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 解剖構造における組織のイメージングのためのシステム、方法、コンピュータ読取可能媒体及び使用
JP2010512904A (ja) * 2006-12-19 2010-04-30 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 不透明媒体のイメージング
WO2010087477A1 (ja) * 2009-01-30 2010-08-05 富士フイルム株式会社 計測対象保持具、生体保持具及び光計測装置
WO2010087478A1 (ja) * 2009-01-30 2010-08-05 富士フイルム株式会社 光断層情報の生成方法、光断層情報生成装置及び記憶媒体
JP2010236903A (ja) * 2009-03-30 2010-10-21 Fujifilm Corp 計測対象保持具
JP2011505954A (ja) * 2007-12-17 2011-03-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 混濁媒体の内部における不均質性の存在を検出するための方法及び、混濁媒体の内部を画像化するための装置
JP2011196693A (ja) * 2010-03-17 2011-10-06 Kitasato Institute オプティカル・コヒーレンス・トモグラフィー装置及び断層像の撮影方法
JP2012515920A (ja) * 2009-01-23 2012-07-12 ジェファソン サイエンス アソシエーツ リミテッド ライアビリティ カンパニー 挿入可能な経直腸プローブを有する専用のモバイル高解像前立腺petイメージャ
CN102781307A (zh) * 2009-09-22 2012-11-14 文森医学公司 用于漫射性介质虚拟折射率匹配的系统和方法
JP2013530426A (ja) * 2010-06-14 2013-07-25 ハミルトン−ソーン インコーポレイテッド 生細胞操作用の装置及び方法
JP2014039816A (ja) * 2012-08-15 2014-03-06 Aspect Imaging Ltd レンダリングされた画像を発生するmri画像処理システム
JP2014039818A (ja) * 2012-08-15 2014-03-06 Aspect Imaging Ltd 臨床診断及び臨床前診断用の複数の異種撮像システム
WO2015037055A1 (ja) * 2013-09-10 2015-03-19 株式会社島津製作所 蛍光画像取得装置
JP2016540537A (ja) * 2013-10-23 2016-12-28 ヴェリリー ライフ サイエンシズ エルエルシー 変調源を有する非侵襲的な分析物検出システム
JP2016540539A (ja) * 2013-10-23 2016-12-28 ヴェリリー ライフ サイエンシズ エルエルシー 外部磁界による血管系内の磁性粒子の空間変調
JP2016540534A (ja) * 2013-10-23 2016-12-28 ヴェリリー ライフ サイエンシズ エルエルシー 分析物と背景信号とを区別するための応答信号の変調
JP2017116555A (ja) * 2007-12-19 2017-06-29 シンギュレックス・インコーポレイテッド 単一分子検出走査分析器およびその使用方法
JP2022179782A (ja) * 2016-04-01 2022-12-02 ブラック ライト サージカル, インコーポレイテッド 時間分解蛍光分光法のためのシステム、デバイス、および方法

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