JP2004510160A5 - - Google Patents
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- Publication number
- JP2004510160A5 JP2004510160A5 JP2002530643A JP2002530643A JP2004510160A5 JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5 JP 2002530643 A JP2002530643 A JP 2002530643A JP 2002530643 A JP2002530643 A JP 2002530643A JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5
- Authority
- JP
- Japan
- Prior art keywords
- linker
- reactive functional
- functional group
- complex
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10048417A DE10048417A1 (de) | 2000-09-29 | 2000-09-29 | Verbindungen mit verzweigtem Linker |
| PCT/EP2001/011118 WO2002027315A2 (en) | 2000-09-29 | 2001-09-26 | Compounds with a branched linker |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004510160A JP2004510160A (ja) | 2004-04-02 |
| JP2004510160A5 true JP2004510160A5 (https=) | 2005-03-03 |
| JP3647845B2 JP3647845B2 (ja) | 2005-05-18 |
Family
ID=7658168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530643A Expired - Lifetime JP3647845B2 (ja) | 2000-09-29 | 2001-09-26 | 分枝リンカーを有する化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040086943A1 (https=) |
| EP (1) | EP1327146B1 (https=) |
| JP (1) | JP3647845B2 (https=) |
| AT (1) | ATE304709T1 (https=) |
| AU (1) | AU2002215904A1 (https=) |
| CA (1) | CA2423916C (https=) |
| DE (2) | DE10048417A1 (https=) |
| DK (1) | DK1327146T3 (https=) |
| ES (1) | ES2248405T3 (https=) |
| WO (1) | WO2002027315A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100361933B1 (ko) | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| US6858210B1 (en) | 1998-06-09 | 2005-02-22 | La Jolla Pharmaceutical Co. | Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same |
| WO2001093914A2 (en) | 2000-06-08 | 2001-12-13 | La Jolla Pharmaceutical Company | Multivalent platform molecules comprising high molecular weight polyethylene oxide |
| US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
| AU2002311919B8 (en) | 2001-05-11 | 2007-03-22 | Ludwig Institute For Cancer Research Ltd | Specific binding proteins and uses thereof |
| EP2423335B1 (en) | 2001-06-21 | 2014-05-14 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same |
| DE10227599B4 (de) * | 2002-06-20 | 2005-04-28 | Proteome Factory Ag | Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe |
| AU2003260243A1 (en) * | 2002-07-19 | 2004-03-03 | Mologen Ag | Dna expression construct for multiple gene expression |
| GB0329825D0 (en) * | 2003-12-23 | 2004-01-28 | Celltech R&D Ltd | Biological products |
| JP4920415B2 (ja) * | 2004-07-30 | 2012-04-18 | 株式会社先端生命科学研究所 | プローブ複合体 |
| RU2410431C2 (ru) | 2005-11-25 | 2011-01-27 | Мологен Аг | Днк-конструкции для специфического ингибирования экспрессии генов посредством рнк-интерференции |
| GB0607479D0 (en) * | 2006-04-13 | 2006-05-24 | Johnson Matthey Plc | Adhesion promoting compound |
| US9090693B2 (en) | 2007-01-25 | 2015-07-28 | Dana-Farber Cancer Institute | Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease |
| CA2680854C (en) | 2007-03-15 | 2017-02-14 | Ludwig Institute For Cancer Research | Treatment method using egfr antibodies and src inhibitors and related formulations |
| CN108424454B (zh) | 2007-08-14 | 2022-05-31 | 路德维格癌症研究所有限公司 | 靶向egf受体的单克隆抗体175及其衍生物和用途 |
| US20110177619A1 (en) * | 2008-07-14 | 2011-07-21 | Andrew Metters | In vitro diagnostic markers comprising carbon nanoparticles and kits |
| CN103588801A (zh) * | 2013-12-02 | 2014-02-19 | 天津大港油田圣达科技有限公司 | 一种微量元素井间示踪剂的使用方法 |
| AU2019403552A1 (en) * | 2018-12-21 | 2021-06-17 | Seagen Inc. | ADCs with thiol multiplex linkers |
| US12061200B2 (en) | 2018-12-28 | 2024-08-13 | Abbott Laboratories | Direct detection of single molecules on microparticles |
| CA3162257A1 (en) * | 2019-12-18 | 2021-06-24 | Bedilu ALLO | Mass cytometry reagents and methods for signal amplification |
| CN119775256B (zh) * | 2024-12-31 | 2025-09-19 | 英科新创（苏州）生物科技有限公司 | 吖啶磺酰胺衍生物、制备方法、其应用及试剂盒 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK365785A (da) * | 1984-09-17 | 1986-03-18 | Hoffmann La Roche | Metalcomplexer |
| US5075447A (en) * | 1984-09-17 | 1991-12-24 | Hoffmann-La Roche Inc. | Ruthenium complexes useful as carriers for immunologically active materials |
| FR2579224B1 (fr) * | 1985-03-25 | 1987-05-22 | Genetica | Procede de preparation microbiologique de la serum-albumine humaine |
| US5750409A (en) * | 1991-11-18 | 1998-05-12 | Boehringer Mannheim Gmbh | Pentacyclic compounds and their use as absorption or fluorescent dyes |
| GB9215780D0 (en) * | 1992-07-24 | 1992-09-09 | Univ London Pharmacy | Peptide compounds |
| DE4310141A1 (de) * | 1993-03-29 | 1994-10-06 | Boehringer Mannheim Gmbh | Homobidentale trifunktionelle Linker |
| GB9407812D0 (en) * | 1994-04-20 | 1994-06-15 | Nycomed Salutar Inc | Compounds |
| DE59507438D1 (de) * | 1994-07-25 | 2000-01-20 | Roche Diagnostics Gmbh | Hydrophile metallkomplexe |
| DE59511054D1 (de) * | 1994-07-25 | 2006-08-10 | Roche Diagnostics Gmbh | Bestimmung von spezifischem immunglobulin unter verwendung multipler antigene |
| CN1114106C (zh) * | 1994-07-25 | 2003-07-09 | 罗切诊断学有限公司 | 金属螯合物标记的肽及其制备方法 |
| US5958783A (en) * | 1994-07-25 | 1999-09-28 | Roche Diagnostics Gmbh | Metal complexes with a charged linker |
| ATE214073T1 (de) * | 1994-07-25 | 2002-03-15 | Roche Diagnostics Gmbh | Hapten-markierte peptide |
| US5718915A (en) * | 1994-10-31 | 1998-02-17 | Burstein Laboratories, Inc. | Antiviral liposome having coupled target-binding moiety and hydrolytic enzyme |
| DE19519973A1 (de) * | 1995-05-31 | 1996-12-05 | Boehringer Mannheim Gmbh | Entstörungsreagenz für die Bestimmung eines Analyten mit einem lumineszenzfähigen Metallkomplex |
| US5714360A (en) * | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
| JP2001505194A (ja) * | 1996-11-05 | 2001-04-17 | ブリストル―マイヤーズ・スクイブ・カンパニー | 分枝ペプチド・リンカー |
| JP4078032B2 (ja) * | 1998-03-12 | 2008-04-23 | ネクター セラピューティックス エイエル，コーポレイション | 近位の反応性基を持つポリ（エチレングリコール）誘導体 |
| DE19811582A1 (de) * | 1998-03-17 | 1999-09-23 | Roche Diagnostics Gmbh | Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen |
| US6153655A (en) * | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| CN1178800C (zh) * | 1998-09-29 | 2004-12-08 | 惠普公司 | 加工小册子的方法和设备 |
| GB2413081A (en) * | 2004-04-13 | 2005-10-19 | Sca Hygiene Prod Ab | Absorbant article with folded side flap portions and method of manufacture |
-
2000
- 2000-09-29 DE DE10048417A patent/DE10048417A1/de not_active Withdrawn
-
2001
- 2001-09-26 EP EP01985752A patent/EP1327146B1/en not_active Expired - Lifetime
- 2001-09-26 DE DE60113445T patent/DE60113445T2/de not_active Expired - Lifetime
- 2001-09-26 DK DK01985752T patent/DK1327146T3/da active
- 2001-09-26 AU AU2002215904A patent/AU2002215904A1/en not_active Abandoned
- 2001-09-26 US US10/381,944 patent/US20040086943A1/en not_active Abandoned
- 2001-09-26 JP JP2002530643A patent/JP3647845B2/ja not_active Expired - Lifetime
- 2001-09-26 WO PCT/EP2001/011118 patent/WO2002027315A2/en not_active Ceased
- 2001-09-26 AT AT01985752T patent/ATE304709T1/de active
- 2001-09-26 ES ES01985752T patent/ES2248405T3/es not_active Expired - Lifetime
- 2001-09-26 CA CA002423916A patent/CA2423916C/en not_active Expired - Lifetime
-
2009
- 2009-02-13 US US12/370,886 patent/US20090264618A1/en not_active Abandoned
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