JP2004510160A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004510160A5 JP2004510160A5 JP2002530643A JP2002530643A JP2004510160A5 JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5 JP 2002530643 A JP2002530643 A JP 2002530643A JP 2002530643 A JP2002530643 A JP 2002530643A JP 2004510160 A5 JP2004510160 A5 JP 2004510160A5
- Authority
- JP
- Japan
- Prior art keywords
- linker
- reactive functional
- functional group
- complex
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10048417A DE10048417A1 (de) | 2000-09-29 | 2000-09-29 | Verbindungen mit verzweigtem Linker |
| PCT/EP2001/011118 WO2002027315A2 (en) | 2000-09-29 | 2001-09-26 | Compounds with a branched linker |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004510160A JP2004510160A (ja) | 2004-04-02 |
| JP2004510160A5 true JP2004510160A5 (https=) | 2005-03-03 |
| JP3647845B2 JP3647845B2 (ja) | 2005-05-18 |
Family
ID=7658168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530643A Expired - Lifetime JP3647845B2 (ja) | 2000-09-29 | 2001-09-26 | 分枝リンカーを有する化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040086943A1 (https=) |
| EP (1) | EP1327146B1 (https=) |
| JP (1) | JP3647845B2 (https=) |
| AT (1) | ATE304709T1 (https=) |
| AU (1) | AU2002215904A1 (https=) |
| CA (1) | CA2423916C (https=) |
| DE (2) | DE10048417A1 (https=) |
| DK (1) | DK1327146T3 (https=) |
| ES (1) | ES2248405T3 (https=) |
| WO (1) | WO2002027315A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100361933B1 (ko) | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| US6858210B1 (en) | 1998-06-09 | 2005-02-22 | La Jolla Pharmaceutical Co. | Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same |
| CN1434726A (zh) | 2000-06-08 | 2003-08-06 | 拉卓拉药物公司 | 包含高分子量聚环氧乙烷的多价平台分子 |
| EP1392359B2 (en) | 2001-05-11 | 2013-03-13 | Ludwig Institute for Cancer Research Ltd. | Specific binding proteins and uses thereof |
| US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
| CA2451974C (en) | 2001-06-21 | 2014-10-14 | Karen L. Fearon | Chimeric immunomodulatory compounds and methods of using the same |
| DE10227599B4 (de) * | 2002-06-20 | 2005-04-28 | Proteome Factory Ag | Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe |
| ES2280829T3 (es) * | 2002-07-19 | 2007-09-16 | Mologen Ag | Constructo de expresion de adn para la expresion de multiples genes. |
| GB0329825D0 (en) * | 2003-12-23 | 2004-01-28 | Celltech R&D Ltd | Biological products |
| DE602005023624D1 (de) * | 2004-07-30 | 2010-10-28 | Advanced Life Science Inst Inc | Sondenkomplex |
| WO2007059760A1 (de) | 2005-11-25 | 2007-05-31 | Mologen Ag | Dna-konstrukte zur spezifischen hemmung der genexpression durch rna-interferenz |
| GB0607479D0 (en) * | 2006-04-13 | 2006-05-24 | Johnson Matthey Plc | Adhesion promoting compound |
| US9090693B2 (en) | 2007-01-25 | 2015-07-28 | Dana-Farber Cancer Institute | Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease |
| ES2542152T3 (es) | 2007-03-15 | 2015-07-31 | Ludwig Institute For Cancer Research Ltd. | Método de tratamiento que emplea anticuerpos de EGFR e inhibidores de Src y formulaciones relacionadas |
| CN108424454B (zh) | 2007-08-14 | 2022-05-31 | 路德维格癌症研究所有限公司 | 靶向egf受体的单克隆抗体175及其衍生物和用途 |
| EP2318051A4 (en) * | 2008-07-14 | 2012-12-26 | Andrew Metters | IN VITRO DIAGNOSTIC MARKERS COMPRISING CARBON NANOPARTICLES AND KITS |
| CN103588801A (zh) * | 2013-12-02 | 2014-02-19 | 天津大港油田圣达科技有限公司 | 一种微量元素井间示踪剂的使用方法 |
| EP3897734A4 (en) * | 2018-12-21 | 2022-12-07 | Seagen Inc. | ADC COMPRISING MULTIPLEX THIOL LINKERS |
| JP7493513B2 (ja) | 2018-12-28 | 2024-05-31 | アボット・ラボラトリーズ | 微粒子上の１分子の直接検出 |
| CN115135680A (zh) * | 2019-12-18 | 2022-09-30 | 标准生物工具加拿大公司 | 用于信号放大的质谱细胞术试剂和方法 |
| CN119775256B (zh) * | 2024-12-31 | 2025-09-19 | 英科新创（苏州）生物科技有限公司 | 吖啶磺酰胺衍生物、制备方法、其应用及试剂盒 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK365785A (da) * | 1984-09-17 | 1986-03-18 | Hoffmann La Roche | Metalcomplexer |
| US5075447A (en) * | 1984-09-17 | 1991-12-24 | Hoffmann-La Roche Inc. | Ruthenium complexes useful as carriers for immunologically active materials |
| FR2579224B1 (fr) * | 1985-03-25 | 1987-05-22 | Genetica | Procede de preparation microbiologique de la serum-albumine humaine |
| US5750409A (en) * | 1991-11-18 | 1998-05-12 | Boehringer Mannheim Gmbh | Pentacyclic compounds and their use as absorption or fluorescent dyes |
| GB9215780D0 (en) * | 1992-07-24 | 1992-09-09 | Univ London Pharmacy | Peptide compounds |
| DE4310141A1 (de) * | 1993-03-29 | 1994-10-06 | Boehringer Mannheim Gmbh | Homobidentale trifunktionelle Linker |
| GB9407812D0 (en) * | 1994-04-20 | 1994-06-15 | Nycomed Salutar Inc | Compounds |
| AU689626B2 (en) * | 1994-07-25 | 1998-04-02 | Boehringer Mannheim Gmbh | Peptides marked with metal chelates |
| DE59507438D1 (de) * | 1994-07-25 | 2000-01-20 | Roche Diagnostics Gmbh | Hydrophile metallkomplexe |
| FI961349A7 (fi) * | 1994-07-25 | 1996-03-25 | Roche Diagnostics Gmbh | Metallikompleksit, joissa on varautunut linkkeri |
| NZ291155A (en) * | 1994-07-25 | 1997-09-22 | Boehringer Mannheim Gmbh | Production of hapten labelled peptides and their use |
| CA2195753C (en) * | 1994-07-25 | 2008-12-16 | Ursula-Henrike Wienhues | Determination of a specific immunoglobulin using multiple antigens |
| US5718915A (en) * | 1994-10-31 | 1998-02-17 | Burstein Laboratories, Inc. | Antiviral liposome having coupled target-binding moiety and hydrolytic enzyme |
| DE19519973A1 (de) * | 1995-05-31 | 1996-12-05 | Boehringer Mannheim Gmbh | Entstörungsreagenz für die Bestimmung eines Analyten mit einem lumineszenzfähigen Metallkomplex |
| US5714360A (en) * | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
| JP2001505194A (ja) * | 1996-11-05 | 2001-04-17 | ブリストル―マイヤーズ・スクイブ・カンパニー | 分枝ペプチド・リンカー |
| DK1411075T3 (da) * | 1998-03-12 | 2008-10-27 | Nektar Therapeutics Al Corp | Fremgangsmåde til fremstilling af polymerkonjugater |
| DE19811582A1 (de) * | 1998-03-17 | 1999-09-23 | Roche Diagnostics Gmbh | Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen |
| US6153655A (en) * | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| DE69915322T2 (de) * | 1998-09-29 | 2005-02-24 | Hewlett-Packard Co.(A Delaware Corporation), Palo Alto | Verfahren und vorrichtung zur herstellung von broschüren |
| GB2413081A (en) * | 2004-04-13 | 2005-10-19 | Sca Hygiene Prod Ab | Absorbant article with folded side flap portions and method of manufacture |
-
2000
- 2000-09-29 DE DE10048417A patent/DE10048417A1/de not_active Withdrawn
-
2001
- 2001-09-26 EP EP01985752A patent/EP1327146B1/en not_active Expired - Lifetime
- 2001-09-26 DK DK01985752T patent/DK1327146T3/da active
- 2001-09-26 AU AU2002215904A patent/AU2002215904A1/en not_active Abandoned
- 2001-09-26 ES ES01985752T patent/ES2248405T3/es not_active Expired - Lifetime
- 2001-09-26 AT AT01985752T patent/ATE304709T1/de active
- 2001-09-26 CA CA002423916A patent/CA2423916C/en not_active Expired - Lifetime
- 2001-09-26 US US10/381,944 patent/US20040086943A1/en not_active Abandoned
- 2001-09-26 JP JP2002530643A patent/JP3647845B2/ja not_active Expired - Lifetime
- 2001-09-26 DE DE60113445T patent/DE60113445T2/de not_active Expired - Lifetime
- 2001-09-26 WO PCT/EP2001/011118 patent/WO2002027315A2/en not_active Ceased
-
2009
- 2009-02-13 US US12/370,886 patent/US20090264618A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004510160A5 (https=) | ||
| US6670199B2 (en) | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces | |
| EP0406473B1 (en) | Ion capture reagents and methods for performing binding assays | |
| JP2002513556A5 (https=) | ||
| AU3150400A (en) | Immobilization of molecules on surfaces via polymer brushes | |
| JP2005522210A5 (https=) | ||
| CN101363870A (zh) | 生物传感芯片及其制备方法 | |
| AU654833B2 (en) | The use of pairs of peptides with extremely high specific affinity for one another in the area of in vitro diagnosis | |
| JP2004512258A5 (https=) | ||
| WO1999017120A1 (en) | Preparing conjugates using polyethylene glycol linkers | |
| JPH10509731A (ja) | ホスファターゼ活性化架橋剤、結合剤及び還元剤とその使用方法、並びにホスファターゼ活性化架橋剤及び結合剤を含む試薬 | |
| US5518882A (en) | Immunological methods of component selection and recovery | |
| JP2002535016A5 (https=) | ||
| EP1176423A1 (en) | Surface-attached polyfunctional polymer networks for sensor chips | |
| JPH11124396A (ja) | 樹状ポリペプチド | |
| JP2824516B2 (ja) | 免疫学的に検出可能な物質の測定法、反応容器及びイムノアッセイ原理による方法における種々のパラメーターの測定法 | |
| WO2003104424A2 (en) | Novel molecular conjugates for signal amplification | |
| JPH0587520B2 (https=) | ||
| CN110501495A (zh) | 活化氨基固相颗粒与免疫氨基固相颗粒及其制备方法和应用及试剂盒 | |
| US20050282884A1 (en) | N-aryl-carbamic acid ester-derived and valeric acid ester-derived cross-linkers and conjugates, and methods for their synthesis and use | |
| JPH03255959A (ja) | ポリマー | |
| JP2509840B2 (ja) | 免疫測定法及び免疫測定用試薬キット | |
| JPH08133990A (ja) | 反応性マイクロスフェアー | |
| KR100668337B1 (ko) | 단백질에 비하여 핵산에 대한 결합력이 선택적으로 높은ｐＨ 의존성 이온 교환물질, 그가 고정화되어 있는 고체기판, 및 상기 물질 및 고체 기판을 이용하여 핵산을분리하는 방법 | |
| JP2547149B2 (ja) | 免疫測定法及び免疫測定用試薬キット |