JP2004508410A5 - - Google Patents
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- JP2004508410A5 JP2004508410A5 JP2002526401A JP2002526401A JP2004508410A5 JP 2004508410 A5 JP2004508410 A5 JP 2004508410A5 JP 2002526401 A JP2002526401 A JP 2002526401A JP 2002526401 A JP2002526401 A JP 2002526401A JP 2004508410 A5 JP2004508410 A5 JP 2004508410A5
- Authority
- JP
- Japan
- Prior art keywords
- bone
- medicament
- disease
- insufficient
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 description 5
- 208000006386 Bone Resorption Diseases 0.000 description 3
- 230000024279 bone resorption Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000011164 ossification Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 206010065687 Bone loss Diseases 0.000 description 1
- 208000037147 Hypercalcaemia Diseases 0.000 description 1
- 201000002980 Hyperparathyroidism Diseases 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 208000010191 Osteitis Deformans Diseases 0.000 description 1
- 208000003076 Osteolysis Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 208000027868 Paget disease Diseases 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 230000000148 hypercalcaemia Effects 0.000 description 1
- 208000030915 hypercalcemia disease Diseases 0.000 description 1
- 208000029791 lytic metastatic bone lesion Diseases 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 208000027202 mammary Paget disease Diseases 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 208000005368 osteomalacia Diseases 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0022844.5 | 2000-09-18 | ||
| GB0022844A GB0022844D0 (en) | 2000-09-18 | 2000-09-18 | Use of GLP-1 and GLP-2 peptides |
| GB0029920A GB0029920D0 (en) | 2000-12-07 | 2000-12-07 | Use of glp-1 and glp-2 peptides |
| GB0029920.6 | 2000-12-07 | ||
| PCT/EP2001/010714 WO2002022151A2 (en) | 2000-09-18 | 2001-09-17 | Use of glp-1 and flp-2 peptides for treatment of bone disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004508410A JP2004508410A (ja) | 2004-03-18 |
| JP2004508410A5 true JP2004508410A5 (OSRAM) | 2008-10-23 |
| JP5161412B2 JP5161412B2 (ja) | 2013-03-13 |
Family
ID=26245018
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002526401A Expired - Fee Related JP5161412B2 (ja) | 2000-09-18 | 2001-09-17 | Glp−1及びglp−2ペプチドの使用方法 |
| JP2002528284A Expired - Fee Related JP5189723B2 (ja) | 2000-09-18 | 2001-09-18 | 骨関連疾患及び栄養関連疾患の治療、予防、診断及び予後のためにglpを使用する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002528284A Expired - Fee Related JP5189723B2 (ja) | 2000-09-18 | 2001-09-18 | 骨関連疾患及び栄養関連疾患の治療、予防、診断及び予後のためにglpを使用する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6770620B2 (OSRAM) |
| EP (3) | EP1970072A1 (OSRAM) |
| JP (2) | JP5161412B2 (OSRAM) |
| AT (2) | ATE396738T1 (OSRAM) |
| AU (2) | AU2002213925A1 (OSRAM) |
| CY (2) | CY1108263T1 (OSRAM) |
| DE (2) | DE60134251D1 (OSRAM) |
| DK (2) | DK1326630T3 (OSRAM) |
| ES (2) | ES2310192T3 (OSRAM) |
| PT (2) | PT1326630E (OSRAM) |
| WO (2) | WO2002022151A2 (OSRAM) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| AU2001266557A1 (en) | 2000-04-12 | 2001-10-23 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20070135345A1 (en) * | 2000-09-18 | 2007-06-14 | Henriksen Dennis B | Use of GLP-2 for the treatment or prevention, of bone-related disorders |
| DK1326630T3 (da) * | 2000-09-18 | 2008-09-15 | Sanos Bioscience As | Anvendelse af GLP-2-peptider |
| US7371721B2 (en) * | 2000-09-18 | 2008-05-13 | Sanos Bioscience A/S | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes |
| US20080249016A1 (en) * | 2000-09-18 | 2008-10-09 | Sanos Bioscience A/S | Use of GLP-2 in a combination treatment for bone-related disorders |
| US7186683B2 (en) * | 2000-09-18 | 2007-03-06 | Sanos Bioscience A/S | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders |
| RO120121B1 (ro) * | 2000-12-18 | 2005-09-30 | Elena Ionaşcu | Soluţie injectabilă, cu efect antiinflamator, procedeu de obţinere şi metodă de tratament a bolilor autoimune |
| CA2347330C (en) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
| DE10135315A1 (de) * | 2001-07-19 | 2003-01-30 | Bayer Ag | Stents |
| JP5424521B2 (ja) | 2001-12-21 | 2014-02-26 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | アルブミン融合タンパク質 |
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| CA2525574C (en) | 2003-05-15 | 2015-06-30 | Trustees Of Tufts College | Stable analogs of peptide and polypeptide therapeutics |
| EP1734955A2 (en) * | 2004-01-13 | 2006-12-27 | Duke University | Compositions of an anticonvulsant and an antipsychotic drug for affecting weigt loss |
| US7713959B2 (en) * | 2004-01-13 | 2010-05-11 | Duke University | Compositions of an anticonvulsant and mirtazapine to prevent weight gain |
| RU2006139930A (ru) * | 2004-05-03 | 2008-06-10 | Дюк Юниверсити (Сша/Сша) (Us) | Составы для содействия снижению веса |
| AU2006242998B2 (en) * | 2005-05-04 | 2012-03-22 | Zealand Pharma A/S | Glucagon-like-peptide-2 (GLP-2) analogues |
| WO2006135660A2 (en) * | 2005-06-10 | 2006-12-21 | University Of Chicago | Therapies involving lymphotoxin beta receptor |
| CN101370488B (zh) | 2005-11-22 | 2012-07-18 | 奥雷西根治疗公司 | 增加胰岛素敏感性的组合物 |
| WO2007089318A2 (en) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions and methods for reducing food cravings |
| WO2007133747A2 (en) * | 2006-05-15 | 2007-11-22 | Wisconsin Alumni Research Foundation | PULMONARY DELIVERY OF 1α,25-DIHYDROXYVITAMIN D3 AND CO-ADMINISTRATION OF PARATHYROID HORMONE OR CALCITONIN |
| US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| EP2051995B1 (en) | 2006-11-08 | 2017-02-08 | Zealand Pharma A/S | Selective glucagon-like-peptide-2 (glp-2) analogues |
| US20080110792A1 (en) * | 2006-11-09 | 2008-05-15 | Orexigen Therapeutics, Inc. | Methods for administering weight loss medications |
| KR101971218B1 (ko) | 2006-11-09 | 2019-08-27 | 오렉시젠 세러퓨틱스 인크. | 신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형 |
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| RU2010114030A (ru) * | 2007-09-11 | 2011-10-20 | Мондобайотек Лабораториз Аг (Li) | Применение пептида в качестве терапевтического средства |
| MX2010012909A (es) * | 2008-05-30 | 2011-02-25 | Orexigen Therapeutics Inc | Metodos para tratamiento de condiciones de grasa visceral. |
| WO2010033240A2 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
| WO2010042145A1 (en) * | 2008-09-19 | 2010-04-15 | Nektar Therapeutics | Polymer conjugates of glp-2-like peptides |
| DK3228320T3 (da) | 2008-10-17 | 2020-03-09 | Sanofi Aventis Deutschland | Kombination af et insulin og en glp-1-agonist |
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| EP2311486A1 (en) * | 2009-10-07 | 2011-04-20 | Nestec S.A. | GLP-2 for use in intestine and muscle recovery |
| CN102711804B (zh) | 2009-11-13 | 2015-09-16 | 赛诺菲-安万特德国有限公司 | 包含glp-1激动剂和甲硫氨酸的药物组合物 |
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| AU2011202239C1 (en) | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
| RU2546520C2 (ru) | 2010-08-30 | 2015-04-10 | Санофи-Авентис Дойчланд Гмбх | Применение ave0010 для производства лекарственного средства для лечения сахарного диабета 2 типа |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| KR20140051182A (ko) * | 2011-05-24 | 2014-04-30 | 폴리발러 에스.이.씨. | 특정한 키토산-기재의 나노복합체를 사용하여 sirna를 효과적이고 안전하게 전달하기 위한 조성물 및 방법 |
| BR112014004726A2 (pt) | 2011-08-29 | 2017-04-04 | Sanofi Aventis Deutschland | combinação farmacêutica para uso no controle glicêmico em pacientes de diabetes tipo 2 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| EP2844670B1 (en) | 2012-05-03 | 2017-12-06 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
| IL300868A (en) | 2012-06-06 | 2023-04-01 | Orexigen Therapeutics Inc | Methods for treating overweight and obesity |
| RU2705797C2 (ru) | 2013-04-03 | 2019-11-12 | Санофи | Лечение сахарного диабета с помощью составов инсулинов длительного действия |
| WO2015016682A1 (ko) | 2013-08-01 | 2015-02-05 | 경희대학교 산학협력단 | 당뇨병 예방 또는 치료용 약학적 조성물, 당뇨병 예방 또는 치료 방법, 및 당뇨병 치료제 스크리닝 방법 |
| US10493042B2 (en) | 2013-08-01 | 2019-12-03 | University-Industry Cooperation Group Of Kyung Hee University | Method for preventing or treating diabetes mellitus, and method for screening for diabetes mellitus therapeutic agent |
| US8969371B1 (en) | 2013-12-06 | 2015-03-03 | Orexigen Therapeutics, Inc. | Compositions and methods for weight loss in at risk patient populations |
| ES2949095T3 (es) | 2014-12-12 | 2023-09-25 | Sanofi Aventis Deutschland | Formulación de relación fija de insulina glargina/lixisenatida |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
| WO2016205754A1 (en) | 2015-06-19 | 2016-12-22 | University Of Southern California | Compositions and methods for modified nutrient delivery |
| WO2016205701A1 (en) | 2015-06-19 | 2016-12-22 | University Of Southern California | Enteral fast access tract platform system |
| WO2018009778A1 (en) * | 2016-07-07 | 2018-01-11 | Baylor College Of Medicine | Combination of glp-1 and glp-2 for treating or preventing metabolic diseases, disorders and syndromes |
| US10774127B2 (en) | 2016-10-12 | 2020-09-15 | University Of Copenhagen | Peptide dual agonists of GIPR and GLP2R |
| RU2753193C2 (ru) | 2016-12-09 | 2021-08-12 | Зилэнд Фарма А/С | Ацилированные двойные агонисты glp-1/glp-2 |
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| EP3694537A1 (en) | 2017-10-12 | 2020-08-19 | University of Copenhagen | Combination therapy for treatment of bone disorders |
| EP3699187A1 (en) * | 2019-02-21 | 2020-08-26 | Universite D'angers | Peptide targeting gip and glp-2 receptors for treating bone disorders |
| US20210187077A1 (en) * | 2019-12-23 | 2021-06-24 | Idaho State University | GLP-1 Agonist Conjugates for Sustained Glycemic Control |
| JP2023508175A (ja) * | 2019-12-24 | 2023-03-01 | ハンミ ファーマシューティカル カンパニー リミテッド | Glp-2又はその結合体を含む、代謝性骨疾患の予防又は治療用薬学的組成物 |
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|---|---|---|---|---|
| EP1498425A1 (en) | 1986-05-05 | 2005-01-19 | The General Hospital Corporation | Use of glucagone-like-peptide 1 (GLP-1) derivatives for the preparation of pharmaceutical compositions |
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| US6110949A (en) * | 1999-06-24 | 2000-08-29 | Novartis Ag | N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
| EP1076066A1 (en) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| AU2020501A (en) | 1999-12-08 | 2001-06-18 | 1149336 Ontario Inc. | Chemotherapy treatment |
| WO2001087322A2 (en) * | 2000-05-17 | 2001-11-22 | Bionebraska, Inc. | Peptide pharmaceutical formulations |
| AU2001264791B2 (en) * | 2000-06-16 | 2006-11-23 | Eli Lilly And Company | Glucagon-like peptide-1 analogs |
| WO2002010195A2 (en) * | 2000-08-02 | 2002-02-07 | Theratechnologies Inc. | Modified peptides with increased potency |
| DK1326630T3 (da) * | 2000-09-18 | 2008-09-15 | Sanos Bioscience As | Anvendelse af GLP-2-peptider |
| WO2002066062A2 (en) | 2001-02-01 | 2002-08-29 | Drucker Daniel J | Enhancement of glp-2 activity |
-
2001
- 2001-09-17 DK DK01982302T patent/DK1326630T3/da active
- 2001-09-17 WO PCT/EP2001/010714 patent/WO2002022151A2/en not_active Ceased
- 2001-09-17 DE DE60134251T patent/DE60134251D1/de not_active Expired - Lifetime
- 2001-09-17 AU AU2002213925A patent/AU2002213925A1/en not_active Abandoned
- 2001-09-17 EP EP08156283A patent/EP1970072A1/en not_active Withdrawn
- 2001-09-17 JP JP2002526401A patent/JP5161412B2/ja not_active Expired - Fee Related
- 2001-09-17 ES ES01982302T patent/ES2310192T3/es not_active Expired - Lifetime
- 2001-09-17 EP EP01982302A patent/EP1326630B1/en not_active Expired - Lifetime
- 2001-09-17 AT AT01982302T patent/ATE396738T1/de active
- 2001-09-17 PT PT01982302T patent/PT1326630E/pt unknown
- 2001-09-17 US US09/954,304 patent/US6770620B2/en not_active Expired - Fee Related
- 2001-09-18 DK DK01967517.2T patent/DK1414486T3/da active
- 2001-09-18 JP JP2002528284A patent/JP5189723B2/ja not_active Expired - Fee Related
- 2001-09-18 PT PT01967517T patent/PT1414486E/pt unknown
- 2001-09-18 EP EP01967517A patent/EP1414486B1/en not_active Expired - Lifetime
- 2001-09-18 AT AT01967517T patent/ATE466592T1/de active
- 2001-09-18 DE DE60142084T patent/DE60142084D1/de not_active Expired - Lifetime
- 2001-09-18 WO PCT/GB2001/004178 patent/WO2002024214A2/en not_active Ceased
- 2001-09-18 AU AU2001287892A patent/AU2001287892A1/en not_active Abandoned
- 2001-09-18 ES ES01967517T patent/ES2345874T3/es not_active Expired - Lifetime
-
2003
- 2003-03-18 US US10/391,460 patent/US6943151B2/en not_active Expired - Fee Related
-
2008
- 2008-08-13 CY CY20081100866T patent/CY1108263T1/el unknown
-
2010
- 2010-07-30 CY CY20101100721T patent/CY1110721T1/el unknown
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