AU2001287892A1 - Use of glp -2 in combination with another therapeutic agent in bone-related and nutrition-related disorders - Google Patents
Use of glp -2 in combination with another therapeutic agent in bone-related and nutrition-related disordersInfo
- Publication number
- AU2001287892A1 AU2001287892A1 AU2001287892A AU8789201A AU2001287892A1 AU 2001287892 A1 AU2001287892 A1 AU 2001287892A1 AU 2001287892 A AU2001287892 A AU 2001287892A AU 8789201 A AU8789201 A AU 8789201A AU 2001287892 A1 AU2001287892 A1 AU 2001287892A1
- Authority
- AU
- Australia
- Prior art keywords
- glp
- nutrition
- bone
- combination
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH] (Somatotropin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Abstract
Glucagon-like peptide-2, its analogues and derivatives, for use in the treatment of hyperparathyroidism.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0022844.5 | 2000-09-18 | ||
GB0022844A GB0022844D0 (en) | 2000-09-18 | 2000-09-18 | Use of GLP-1 and GLP-2 peptides |
GB0029920.6 | 2000-12-07 | ||
GB0029920A GB0029920D0 (en) | 2000-12-07 | 2000-12-07 | Use of glp-1 and glp-2 peptides |
PCT/GB2001/004178 WO2002024214A2 (en) | 2000-09-18 | 2001-09-18 | Use of glp -2 in combination with another therapeutic agent in bone-related and nutrition-related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001287892A1 true AU2001287892A1 (en) | 2002-04-02 |
Family
ID=26245018
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002213925A Abandoned AU2002213925A1 (en) | 2000-09-18 | 2001-09-17 | Use of glp-1 and flp-2 peptides for treatment of bone disorders |
AU2001287892A Abandoned AU2001287892A1 (en) | 2000-09-18 | 2001-09-18 | Use of glp -2 in combination with another therapeutic agent in bone-related and nutrition-related disorders |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002213925A Abandoned AU2002213925A1 (en) | 2000-09-18 | 2001-09-17 | Use of glp-1 and flp-2 peptides for treatment of bone disorders |
Country Status (11)
Country | Link |
---|---|
US (2) | US6770620B2 (en) |
EP (3) | EP1970072A1 (en) |
JP (2) | JP5161412B2 (en) |
AT (2) | ATE396738T1 (en) |
AU (2) | AU2002213925A1 (en) |
CY (2) | CY1108263T1 (en) |
DE (2) | DE60134251D1 (en) |
DK (2) | DK1326630T3 (en) |
ES (2) | ES2310192T3 (en) |
PT (2) | PT1326630E (en) |
WO (2) | WO2002022151A2 (en) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7371721B2 (en) * | 2000-09-18 | 2008-05-13 | Sanos Bioscience A/S | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes |
US7186683B2 (en) * | 2000-09-18 | 2007-03-06 | Sanos Bioscience A/S | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders |
DE60134251D1 (en) * | 2000-09-18 | 2008-07-10 | Sanos Bioscience As | USE OF GLP-2 PEPTIDES |
US20070135345A1 (en) * | 2000-09-18 | 2007-06-14 | Henriksen Dennis B | Use of GLP-2 for the treatment or prevention, of bone-related disorders |
US20080249016A1 (en) * | 2000-09-18 | 2008-10-09 | Sanos Bioscience A/S | Use of GLP-2 in a combination treatment for bone-related disorders |
RO120121B1 (en) * | 2000-12-18 | 2005-09-30 | Elena Ionaşcu | Injectable solution having antiinflammatory effect, process for preparing the same and method for treating autoimmune diseases |
CA2347330C (en) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
DE10135315A1 (en) * | 2001-07-19 | 2003-01-30 | Bayer Ag | stents |
EP2261250B1 (en) | 2001-12-21 | 2015-07-01 | Human Genome Sciences, Inc. | GCSF-Albumin fusion proteins |
US20050215552A1 (en) * | 2002-05-17 | 2005-09-29 | Gadde Kishore M | Method for treating obesity |
EP1505967B1 (en) | 2002-05-17 | 2016-07-13 | Duke University | Method for treating obesity |
WO2004084859A2 (en) * | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
WO2004085471A2 (en) * | 2003-03-24 | 2004-10-07 | Novo Nordisk A/S | Glp-2 derivatives |
EP1870096A3 (en) * | 2003-04-29 | 2011-04-20 | Orexigen Therapeutics, Inc. | Compositions for affecting weight loss |
DK1617832T3 (en) * | 2003-04-29 | 2008-07-07 | Orexigen Therapeutics Inc | Preparations for the effect of weight loss |
US7259234B2 (en) | 2003-05-15 | 2007-08-21 | Trustees Of Tufts College | Stable analogs of peptide and polypeptide therapeutics |
US7713959B2 (en) * | 2004-01-13 | 2010-05-11 | Duke University | Compositions of an anticonvulsant and mirtazapine to prevent weight gain |
WO2005070461A2 (en) * | 2004-01-13 | 2005-08-04 | Duke University | Compositions of an anticonvulsant and an antipsychotic drug for affecting weight loss |
BRPI0510593A (en) * | 2004-05-03 | 2007-11-20 | Univ Duke | compositions to affect weight loss |
PT1877435E (en) * | 2005-05-04 | 2011-05-24 | Zealand Pharma As | Glucagon-like-peptide-2 (glp-2) analogues |
WO2006135660A2 (en) * | 2005-06-10 | 2006-12-21 | University Of Chicago | Therapies involving lymphotoxin beta receptor |
EP1951212A2 (en) | 2005-11-22 | 2008-08-06 | Orexigen Therapeutics, Inc. | Compositions and methods for increasing insulin sensitivity |
WO2007089318A2 (en) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions and methods for reducing food cravings |
CA2651283A1 (en) * | 2006-05-15 | 2007-11-22 | Wisconsin Alumni Research Foundation | Pulmonary delivery of 1.alpha.,25-dihydroxyvitamin d3 and co-administration of parathyroid hormone or calcitonin |
US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
NZ597554A (en) | 2006-11-08 | 2014-04-30 | Zealand Pharma As | Selective glucagon-like-peptide-2 (glp-2) analogues |
WO2008060964A2 (en) | 2006-11-09 | 2008-05-22 | Orexigen Therapeutics, Inc. | Unit dosage package and methods for administering weight loss medications |
KR20190042766A (en) | 2006-11-09 | 2019-04-24 | 오렉시젠 세러퓨틱스 인크. | Layered pharmaceutical formulations comprising an intermediate rapidly dissolving layer |
EP2124907B1 (en) | 2007-03-19 | 2018-05-30 | Vita Sciences, Llc | Transdermal patch and method for delivery of vitamin b12 |
WO2009039991A2 (en) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Use of aviptadil as a therapeutic agent |
EP2303025A4 (en) * | 2008-05-30 | 2012-07-04 | Orexigen Therapeutics Inc | Methods for treating visceral fat conditions |
EP2337585A1 (en) * | 2008-09-19 | 2011-06-29 | Nektar Therapeutics | Polymer conjugates of glp-2-like peptides |
CA2737040C (en) | 2008-09-19 | 2017-05-02 | Nektar Therapeutics | Polymer conjugates of therapeutic peptides |
SI2349324T1 (en) | 2008-10-17 | 2018-01-31 | Sanofi-Aventis Deutschland Gmbh | Combination of an insulin and a glp-1 agonist |
EA201290158A1 (en) * | 2009-09-23 | 2012-08-30 | Биокиер, Инк. | COMPOSITION AND METHOD OF TREATMENT OF DIABETES |
EP2311486A1 (en) * | 2009-10-07 | 2011-04-20 | Nestec S.A. | GLP-2 for use in intestine and muscle recovery |
KR101836070B1 (en) | 2009-11-13 | 2018-03-09 | 사노피-아벤티스 도이칠란트 게엠베하 | Pharmaceutical composition comprising a glp-1 agonist, an insulin, and methionine |
AR078973A1 (en) | 2009-11-13 | 2011-12-14 | Sanofi Aventis Deutschland | PHARMACEUTICAL COMPOSITION THAT INCLUDES AN GLP-1 AND METIONINE AGONIST |
BR112012016783A2 (en) | 2010-01-11 | 2015-09-01 | Orexigen Therapeutics Inc | "Uses of the naltrexone compound or pharmaceutically acceptable salt thereof to bupropion or pharmaceutically acceptable salt thereof or composition thereof and methods for providing therapy" |
AU2011202239C1 (en) | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
SI2611458T1 (en) | 2010-08-30 | 2017-01-31 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
WO2012159215A1 (en) * | 2011-05-24 | 2012-11-29 | Polyvalor S.E.C. | Compositions and methods for efficacious and safe delivery of sirna using specific chitosan-based nanocomplexes |
MX370264B (en) | 2011-08-29 | 2019-12-09 | Sanofi Aventis Deutschland | Pharmaceutical combination for use in glycemic control in diabetes type 2 patients. |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
TR201802689T4 (en) | 2012-05-03 | 2018-03-21 | Zealand Pharma As | Glucagon-like peptide-2 (glp-2) analogs. |
KR20200035501A (en) | 2012-06-06 | 2020-04-03 | 오렉시젠 세러퓨틱스 인크. | Methods of treating overweight and obesity |
CA2907848A1 (en) | 2013-04-03 | 2014-10-09 | Sanofi | Treatment of diabetes mellitus by long-acting formulations of insulins |
WO2015016682A1 (en) * | 2013-08-01 | 2015-02-05 | 경희대학교 산학협력단 | Pharmaceutical composition for preventing or treating diabetes mellitus, method for preventing or treating diabetes mellitus, and method for screening for diabetes mellitus therapeutic agent |
KR101688639B1 (en) | 2013-08-01 | 2016-12-21 | 경희대학교 산학협력단 | Composition for preventing or treating diabetes mellitus, method for preventing or treating diabetes mellitus, and method for screening antidiabetics |
US8969371B1 (en) | 2013-12-06 | 2015-03-03 | Orexigen Therapeutics, Inc. | Compositions and methods for weight loss in at risk patient populations |
HUE062573T2 (en) | 2014-12-12 | 2023-11-28 | Sanofi Aventis Deutschland | Insulin glargine/lixisenatide fixed ratio formulation |
TWI748945B (en) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | Treatment type 2 diabetes mellitus patients |
TW201705975A (en) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | Treatment of type 2 diabetes mellitus patients |
CA2990230A1 (en) | 2015-06-19 | 2016-12-22 | University Of Southern California | Compositions and methods for modified nutrient delivery |
US10744070B2 (en) | 2015-06-19 | 2020-08-18 | University Of Southern California | Enteral fast access tract platform system |
WO2018009778A1 (en) * | 2016-07-07 | 2018-01-11 | Baylor College Of Medicine | Combination of glp-1 and glp-2 for treating or preventing metabolic diseases, disorders and syndromes |
US10774127B2 (en) | 2016-10-12 | 2020-09-15 | University Of Copenhagen | Peptide dual agonists of GIPR and GLP2R |
BR112019010624A2 (en) | 2016-12-09 | 2019-10-22 | Zealand Pharma As | double acylated glp-1 / glp-2 agonists and composition |
US20200261543A1 (en) | 2017-10-12 | 2020-08-20 | University Of Copenhagen | Combination therapy for treatment of bone disorders |
US20210187077A1 (en) * | 2019-12-23 | 2021-06-24 | Idaho State University | GLP-1 Agonist Conjugates for Sustained Glycemic Control |
US20220362347A1 (en) * | 2019-12-24 | 2022-11-17 | Hanmi Pharm. Co., Ltd. | Pharmaceutical composition for preventing or treating metabolic bone diseases, comprising glp-2 or conjugate thereof |
US20230355720A1 (en) * | 2020-09-25 | 2023-11-09 | Hanmi Pharm. Co., Ltd. | Pharmaceutical composition for preventing or treating bone diseases, comprising triple agonist or conjugate thereof having activity with respect to all of glucagon, glp-1 and glp receptors |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1987006941A1 (en) | 1986-05-05 | 1987-11-19 | The General Hospital Corporation | Insulinotropic hormone |
ATE193541T1 (en) | 1989-03-20 | 2000-06-15 | Gen Hospital Corp | INSULINOTROPIC HORMONE |
EP0512042B1 (en) | 1990-01-24 | 1998-04-08 | BUCKLEY, Douglas I. | Glp-1 analogs useful for diabetes treatment |
NZ245015A (en) | 1991-11-05 | 1995-12-21 | Transkaryotic Therapies Inc | Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production |
US5512459A (en) | 1993-07-20 | 1996-04-30 | Bionebraska, Inc. | Enzymatic method for modification or recombinant polypeptides |
US5990077A (en) | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
US6184201B1 (en) | 1995-04-14 | 2001-02-06 | Nps Allelix Corp. | Intestinotrophic glucagon-like peptide-2 analogs |
US5834428A (en) | 1995-04-14 | 1998-11-10 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
US5789379A (en) | 1995-04-14 | 1998-08-04 | Allelix Biopharmaceutical Inc. | Glucagon-like peptide-2 analogs |
DE69740176D1 (en) * | 1996-03-01 | 2011-05-26 | Novo Nordisk As | Appetite inhibiting peptide, composition and use |
US5912229A (en) | 1996-03-01 | 1999-06-15 | Novo Nordisk Als | Use of a pharmaceutical composition comprising an appetite-suppressing peptide |
NZ332281A (en) | 1996-04-12 | 2000-03-27 | Allelix Biopharma | Glucagon-like peptide-2 (GLP-2) analogs for the treatment of bowl disorders resistant to dipeptidyl peptidase IV (DPP-IV) digestion |
EP0909312B1 (en) | 1996-07-05 | 2002-12-04 | Novo Nordisk A/S | Method for the production of polypeptides |
US5994500A (en) | 1996-07-19 | 1999-11-30 | 1149336 Ontario Inc. | Antagonists of intestinotrophic GLP-2 peptides |
JP2000517308A (en) | 1996-08-30 | 2000-12-26 | ノボ ノルディスク アクティーゼルスカブ | GLP-2 derivative |
US6011155A (en) * | 1996-11-07 | 2000-01-04 | Novartis Ag | N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
WO1998024813A2 (en) | 1996-12-06 | 1998-06-11 | Amgen Inc. | Keratinocyte growth factors and their use in combination with glucagon-like peptide derivatives |
US5952301A (en) | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
CA2274989C (en) | 1996-12-13 | 2012-01-31 | Allelix Biopharmaceuticals Inc. | Cloned glucagon-like peptide-2 receptors |
US6077949A (en) | 1996-12-13 | 2000-06-20 | Allelix Biopharmaceuticals, Inc. | Cloned glucagon-like peptide 2 receptors |
WO1998052600A1 (en) * | 1997-05-16 | 1998-11-26 | 1149336 Ontario Inc. | Methods of enhancing functioning of the upper gastrointestinal tract |
US6051557A (en) | 1997-05-16 | 2000-04-18 | 1149336 Ontario Inc. | Methods of enhancing functioning of the upper gastrointestinal tract |
WO1999006059A2 (en) | 1997-07-30 | 1999-02-11 | Board Of Regents, The University Of Texas System | Methods and compositions relating to no-mediated cytotoxicity |
JP2001516765A (en) | 1997-09-12 | 2001-10-02 | ヴォルフ ゲオルグ フォースマン | Compositions for the treatment of diabetes mellitus and obesity |
WO1999037793A1 (en) | 1998-01-23 | 1999-07-29 | Novo Nordisk A/S | Process for making desired polypeptides in yeast |
EP2433623A1 (en) | 1998-02-02 | 2012-03-28 | Trustees Of Tufts College | Use of dipeptidylpeptidase inhibitors to regulate glucose metabolism |
JP2002504527A (en) | 1998-02-27 | 2002-02-12 | ノボ ノルディスク アクティーゼルスカブ | GLP-2 derivatives with more than 25% helical component forming partially organized micellar-like aggregates |
CA2321026A1 (en) | 1998-03-09 | 1999-09-16 | Zealand Pharmaceuticals A/S | Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
FR2777283B1 (en) * | 1998-04-10 | 2000-11-24 | Adir | NOVEL GLUCAGON-PEPTIDE- 1 (7-37) ANALOGUE PEPTIDE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
AU7421598A (en) | 1998-05-11 | 1999-11-29 | 1149336 Ontario Inc. | Methods of enhancing functioning of the large intestine |
KR20010079669A (en) | 1998-08-21 | 2001-08-22 | 바바라 피. 월너 | Regulation of Substrate Activity |
US6193997B1 (en) | 1998-09-27 | 2001-02-27 | Generex Pharmaceuticals Inc. | Proteinic drug delivery system using membrane mimetics |
WO2000020592A1 (en) | 1998-10-07 | 2000-04-13 | Medical College Of Georgia Research Institute, Inc. | Glucose-dependent insulinotropic peptide for use as an osteotropic hormone |
US6416737B1 (en) * | 1998-11-19 | 2002-07-09 | Board Of Trustees Of The University Of Arkansas | Increasing bone strength with selected bisphosphonates |
JP3702181B2 (en) * | 1998-12-07 | 2005-10-05 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | Analogs of GLP-1 |
EP1992641A3 (en) * | 1998-12-07 | 2009-07-29 | Ipsen Pharma | GLP-1 analogues |
CO5150173A1 (en) | 1998-12-10 | 2002-04-29 | Novartis Ag | COMPOUNDS N- (REPLACED GLYCLE) -2-DIPEPTIDYL-IV PEPTIDASE INHIBITING CYANOPIRROLIDINS (DPP-IV) WHICH ARE EFFECTIVE IN THE TREATMENT OF CONDITIONS MEDIATED BY DPP-IV INHIBITION |
US6271200B1 (en) | 1998-12-21 | 2001-08-07 | Generex Pharmaceuticals Inc. | Proteinic drug delivery system using aerosolized membrane-mimetic amphiphiles |
WO2000042026A1 (en) | 1999-01-15 | 2000-07-20 | Novo Nordisk A/S | Non-peptide glp-1 agonists |
GB9905416D0 (en) | 1999-03-09 | 1999-05-05 | Allelix Biopharma | Small molecules having GLP-2 like activity |
US6110949A (en) * | 1999-06-24 | 2000-08-29 | Novartis Ag | N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
EP1076066A1 (en) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
US20030040478A1 (en) | 1999-12-08 | 2003-02-27 | Drucker Daniel J | Chemotherapy treatment |
US20020061838A1 (en) * | 2000-05-17 | 2002-05-23 | Barton Holmquist | Peptide pharmaceutical formulations |
KR100847615B1 (en) * | 2000-06-16 | 2008-07-21 | 일라이 릴리 앤드 캄파니 | Glucagon-like Peptide-1 Analogs |
EP1305338A2 (en) * | 2000-08-02 | 2003-05-02 | Theratechnologies Inc. | Modified peptides with increased potency |
DE60134251D1 (en) * | 2000-09-18 | 2008-07-10 | Sanos Bioscience As | USE OF GLP-2 PEPTIDES |
WO2002066062A2 (en) | 2001-02-01 | 2002-08-29 | Drucker Daniel J | Enhancement of glp-2 activity |
-
2001
- 2001-09-17 DE DE60134251T patent/DE60134251D1/en not_active Expired - Lifetime
- 2001-09-17 PT PT01982302T patent/PT1326630E/en unknown
- 2001-09-17 EP EP08156283A patent/EP1970072A1/en not_active Withdrawn
- 2001-09-17 EP EP01982302A patent/EP1326630B1/en not_active Expired - Lifetime
- 2001-09-17 ES ES01982302T patent/ES2310192T3/en not_active Expired - Lifetime
- 2001-09-17 AU AU2002213925A patent/AU2002213925A1/en not_active Abandoned
- 2001-09-17 US US09/954,304 patent/US6770620B2/en not_active Expired - Fee Related
- 2001-09-17 DK DK01982302T patent/DK1326630T3/en active
- 2001-09-17 WO PCT/EP2001/010714 patent/WO2002022151A2/en active IP Right Grant
- 2001-09-17 AT AT01982302T patent/ATE396738T1/en active
- 2001-09-17 JP JP2002526401A patent/JP5161412B2/en not_active Expired - Fee Related
- 2001-09-18 PT PT01967517T patent/PT1414486E/en unknown
- 2001-09-18 AT AT01967517T patent/ATE466592T1/en active
- 2001-09-18 WO PCT/GB2001/004178 patent/WO2002024214A2/en active Application Filing
- 2001-09-18 JP JP2002528284A patent/JP5189723B2/en not_active Expired - Fee Related
- 2001-09-18 EP EP01967517A patent/EP1414486B1/en not_active Expired - Lifetime
- 2001-09-18 DE DE60142084T patent/DE60142084D1/en not_active Expired - Lifetime
- 2001-09-18 DK DK01967517.2T patent/DK1414486T3/en active
- 2001-09-18 AU AU2001287892A patent/AU2001287892A1/en not_active Abandoned
- 2001-09-18 ES ES01967517T patent/ES2345874T3/en not_active Expired - Lifetime
-
2003
- 2003-03-18 US US10/391,460 patent/US6943151B2/en not_active Expired - Fee Related
-
2008
- 2008-08-13 CY CY20081100866T patent/CY1108263T1/en unknown
-
2010
- 2010-07-30 CY CY20101100721T patent/CY1110721T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP5161412B2 (en) | 2013-03-13 |
CY1108263T1 (en) | 2014-02-12 |
PT1414486E (en) | 2010-07-21 |
WO2002022151A2 (en) | 2002-03-21 |
DK1326630T3 (en) | 2008-09-15 |
EP1414486A2 (en) | 2004-05-06 |
EP1326630B1 (en) | 2008-05-28 |
US6943151B2 (en) | 2005-09-13 |
ES2345874T3 (en) | 2010-10-05 |
WO2002024214A3 (en) | 2004-02-19 |
CY1110721T1 (en) | 2015-06-10 |
EP1970072A1 (en) | 2008-09-17 |
JP2004508410A (en) | 2004-03-18 |
US20020037836A1 (en) | 2002-03-28 |
WO2002024214A2 (en) | 2002-03-28 |
EP1326630A2 (en) | 2003-07-16 |
ATE466592T1 (en) | 2010-05-15 |
US6770620B2 (en) | 2004-08-03 |
JP2004524268A (en) | 2004-08-12 |
DK1414486T3 (en) | 2010-08-30 |
DE60142084D1 (en) | 2010-06-17 |
DE60134251D1 (en) | 2008-07-10 |
US20040082507A1 (en) | 2004-04-29 |
AU2002213925A1 (en) | 2002-03-26 |
ES2310192T3 (en) | 2009-01-01 |
PT1326630E (en) | 2008-09-02 |
JP5189723B2 (en) | 2013-04-24 |
WO2002022151A3 (en) | 2003-03-13 |
EP1414486B1 (en) | 2010-05-05 |
ATE396738T1 (en) | 2008-06-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001287892A1 (en) | Use of glp -2 in combination with another therapeutic agent in bone-related and nutrition-related disorders | |
MXPA03003870A (en) | Combination therapy comprising anti-diabetic and anticonvulsant agents. | |
HK1046105A1 (en) | Methods for glucagon suppression | |
WO2002038052A3 (en) | Steerable loop structure | |
MXPA05008406A (en) | Phenylacetamides and their use as glucokinase modulators. | |
EP2261200A3 (en) | Modified forms of pharmacacologically active agents and uses therefor | |
WO2003018516A3 (en) | Glucagon-like peptide-1 analogs | |
HK1061516A1 (en) | Combinations comprising an antidiarrheal agent and an epothilone or an epothilone derivative | |
AU2001264042A1 (en) | 1,4-diazabicyclo(3.2.2)nonane-phenylisoxazole derivatives, preparation and therapeutic use thereof | |
AU2158601A (en) | Antiviral agent for use in treatment of cancer | |
AU2001264044A1 (en) | 1,4-diazabicyclo(3.2.2)nonabenzoxazole, -benzothiazole and benzimidazole derivatives, preparation and therapeutic use thereof | |
AU2001235595A1 (en) | 4-heteroaryl-1,4-diazabicyclo(3.2.2)nonane, preparation and therapeutic use thereof | |
AUPQ879500A0 (en) | Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease | |
AU3301700A (en) | (n)-sulfonyl-dipeptide derivatives, production and use thereof in therapy | |
AU4789099A (en) | Therapeutic composition based on flavonoids for use in the treatment of tumours with cytotoxic agents | |
MXPA03003032A (en) | Combination therapy for the treatment of estrogen-sensitive disease. | |
AU2002234165A1 (en) | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents | |
ZA200405173B (en) | 2'-halo-3',5'-dialkoxyphen-1'yl-imino-2-imidazoline derivatives and the use thereof for the treatment of urinary incontinence. | |
AU2002210763A1 (en) | Use of 1-ebio in the treatment of bipolar disorders | |
AU6091299A (en) | Treatment device, treatment bed to be used therein and the use thereof | |
WO2002004073A3 (en) | Therapeutic radiation arrangement | |
AU2002368208A8 (en) | Use of 2,3 alkylcarbonyloxybenzoic acids in the treatment of anthrax | |
AU5969500A (en) | 10-formyltetrahydrofolate dehydrogenase as therapeutical agent | |
AU2002223961A1 (en) | Use of chelators in the treatment of macular degenerative disease | |
AU2002313087A1 (en) | Product comprising mikanolide, dihydromikanolide or an analogue thereof combined with another anti-cancer agent for therapeutic use in cancer treatment |