JP2004505087A5 - - Google Patents
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- Publication number
- JP2004505087A5 JP2004505087A5 JP2002515900A JP2002515900A JP2004505087A5 JP 2004505087 A5 JP2004505087 A5 JP 2004505087A5 JP 2002515900 A JP2002515900 A JP 2002515900A JP 2002515900 A JP2002515900 A JP 2002515900A JP 2004505087 A5 JP2004505087 A5 JP 2004505087A5
- Authority
- JP
- Japan
- Prior art keywords
- slurry
- give
- solution
- ethyl
- ethyl alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 235000019441 ethanol Nutrition 0.000 description 4
- 239000002002 slurry Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- 239000012453 solvate Substances 0.000 description 2
- 125000004200 2-methoxyethyl group Chemical group [H]C([H])([H])OC([H])([H])C([H])([H])* 0.000 description 1
- XKMPNUJSWZDBSC-UHFFFAOYSA-N 5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylpyridin-3-yl]-3-ethyl-2-(2-methoxyethyl)-4h-pyrazolo[4,3-d]pyrimidin-7-one;ethyl acetate Chemical compound CCOC(C)=O.C1=C(C=2NC(=O)C3=NN(CCOC)C(CC)=C3N=2)C(OCC)=NC=C1S(=O)(=O)N1CCN(CC)CC1 XKMPNUJSWZDBSC-UHFFFAOYSA-N 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0018656A GB0018656D0 (en) | 2000-07-28 | 2000-07-28 | Pharmaceutically active compounds |
| GB0106464A GB0106464D0 (en) | 2001-03-15 | 2001-03-15 | Crystalline therapeutic agent |
| PCT/IB2001/001280 WO2002010171A1 (en) | 2000-07-28 | 2001-07-18 | Crystalline therapeutic agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004505087A JP2004505087A (ja) | 2004-02-19 |
| JP2004505087A5 true JP2004505087A5 (enExample) | 2007-11-08 |
Family
ID=26244756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002515900A Pending JP2004505087A (ja) | 2000-07-28 | 2001-07-18 | 結晶性治療剤 |
Country Status (45)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004072079A1 (en) * | 2003-02-11 | 2004-08-26 | Pfizer Limited | Hydrated and anhydrous sildenafil hemi-citrate compound |
| EA008596B1 (ru) | 2003-04-29 | 2007-06-29 | Пфайзер Инк. | 5,7-ДИАМИНОПИРАЗОЛО[4,3-d]ПИРИМИДИНЫ, ПОЛЕЗНЫЕ ПРИ ЛЕЧЕНИИ ГИПЕРТЕНЗИИ |
| US7572799B2 (en) | 2003-11-24 | 2009-08-11 | Pfizer Inc | Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors |
| DK1742950T3 (da) | 2004-04-07 | 2009-03-16 | Pfizer Ltd | Pyrazolo-[4,3-D]-pyrimidiner |
| CA2608018C (en) | 2005-05-12 | 2010-07-13 | Pfizer Inc. | Anhydrous crystalline forms of n-[1-(2-ethoxyethyl)-5-(n-ethyl-n-methylamino)-7-(4-methylpyridin-2-yl-amino)-1h-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1371647B1 (en) * | 1998-04-20 | 2005-07-13 | Pfizer Inc. | Pyridine-3-carboxylic acid derivatives and their use as intermediates |
| TWI265925B (en) * | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
-
2001
- 2001-07-18 EP EP01951842A patent/EP1305314B1/en not_active Expired - Lifetime
- 2001-07-18 HR HR20030061A patent/HRP20030061A2/hr not_active Application Discontinuation
- 2001-07-18 DZ DZ013364A patent/DZ3364A1/xx active
- 2001-07-18 ES ES01951842T patent/ES2231521T3/es not_active Expired - Lifetime
- 2001-07-18 EE EEP200300045A patent/EE200300045A/xx unknown
- 2001-07-18 PL PL01365133A patent/PL365133A1/xx unknown
- 2001-07-18 CZ CZ2003126A patent/CZ2003126A3/cs unknown
- 2001-07-18 GE GE5062A patent/GEP20053494B/en unknown
- 2001-07-18 AT AT01951842T patent/ATE286901T1/de not_active IP Right Cessation
- 2001-07-18 CA CA002417264A patent/CA2417264C/en not_active Expired - Fee Related
- 2001-07-18 AU AU2001272690A patent/AU2001272690B2/en not_active Ceased
- 2001-07-18 AU AU7269001A patent/AU7269001A/xx active Pending
- 2001-07-18 MX MXPA03000856 patent/MX233602B/es active IP Right Grant
- 2001-07-18 WO PCT/IB2001/001280 patent/WO2002010171A1/en not_active Ceased
- 2001-07-18 HU HU0302982A patent/HUP0302982A3/hu unknown
- 2001-07-18 IL IL15322601A patent/IL153226A0/xx not_active IP Right Cessation
- 2001-07-18 UA UA2003010715A patent/UA72631C2/uk unknown
- 2001-07-18 KR KR20037001202A patent/KR100457937B1/ko not_active Expired - Fee Related
- 2001-07-18 BR BR0112734-9A patent/BR0112734A/pt not_active IP Right Cessation
- 2001-07-18 OA OA1200300008A patent/OA12337A/fr unknown
- 2001-07-18 PT PT01951842T patent/PT1305314E/pt unknown
- 2001-07-18 JP JP2002515900A patent/JP2004505087A/ja active Pending
- 2001-07-18 DE DE60108398T patent/DE60108398T2/de not_active Expired - Fee Related
- 2001-07-18 CN CNB018133924A patent/CN1207297C/zh not_active Expired - Fee Related
- 2001-07-18 NZ NZ523226A patent/NZ523226A/en unknown
- 2001-07-18 YU YU4703A patent/YU4703A/sh unknown
- 2001-07-18 SK SK57-2003A patent/SK572003A3/sk not_active Application Discontinuation
- 2001-07-18 EA EA200300079A patent/EA004681B1/ru not_active IP Right Cessation
- 2001-07-24 PE PE2001000746A patent/PE20020277A1/es not_active Application Discontinuation
- 2001-07-25 MY MYPI20013530A patent/MY117831A/en unknown
- 2001-07-26 AP APAP/P/2001/002234A patent/AP1400A/en active
- 2001-07-26 AR ARP010103576A patent/AR032628A1/es unknown
- 2001-07-26 DO DO2001000217A patent/DOP2001000217A/es unknown
- 2001-07-26 PH PH12001001922A patent/PH12001001922B1/en unknown
- 2001-07-26 UY UY26854A patent/UY26854A1/es not_active Application Discontinuation
- 2001-07-27 PA PA20018523501A patent/PA8523501A1/es unknown
- 2001-07-27 TW TW090118441A patent/TWI285643B/zh not_active IP Right Cessation
- 2001-07-27 SV SV2001000570A patent/SV2001000570A/es not_active Application Discontinuation
- 2001-07-27 TN TNTNSN01112A patent/TNSN01112A1/fr unknown
-
2002
- 2002-11-12 BG BG107266A patent/BG107266A/bg unknown
- 2002-11-18 IS IS6626A patent/IS6626A/is unknown
- 2002-11-20 IN IN1649MU2002 patent/IN2002MU01649A/en unknown
-
2003
- 2003-01-20 MA MA27003A patent/MA26931A1/fr unknown
- 2003-01-27 NO NO20030416A patent/NO324220B1/no unknown
- 2003-01-28 EC EC2003004454A patent/ECSP034454A/es unknown
- 2003-02-24 ZA ZA200301457A patent/ZA200301457B/en unknown
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