JP2004505052A5 - - Google Patents
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- Publication number
- JP2004505052A5 JP2004505052A5 JP2002515260A JP2002515260A JP2004505052A5 JP 2004505052 A5 JP2004505052 A5 JP 2004505052A5 JP 2002515260 A JP2002515260 A JP 2002515260A JP 2002515260 A JP2002515260 A JP 2002515260A JP 2004505052 A5 JP2004505052 A5 JP 2004505052A5
- Authority
- JP
- Japan
- Prior art keywords
- fentanyl
- equivalent
- pain
- formulation
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- IVLVTNPOHDFFCJ-UHFFFAOYSA-N fentanyl citrate Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 IVLVTNPOHDFFCJ-UHFFFAOYSA-N 0.000 description 25
- 229960002428 fentanyl Drugs 0.000 description 19
- 238000009472 formulation Methods 0.000 description 13
- 239000000203 mixture Substances 0.000 description 13
- 208000002193 Pain Diseases 0.000 description 8
- 239000002904 solvent Substances 0.000 description 5
- 208000005298 acute pain Diseases 0.000 description 4
- 230000000202 analgesic effect Effects 0.000 description 4
- 230000036407 pain Effects 0.000 description 4
- 208000000003 Breakthrough pain Diseases 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
- 239000007923 nasal drop Substances 0.000 description 2
- 239000007922 nasal spray Substances 0.000 description 2
- 229940097496 nasal spray Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010058019 Cancer Pain Diseases 0.000 description 1
- 206010016059 Facial pain Diseases 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 208000004550 Postoperative Pain Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 210000000013 bile duct Anatomy 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 229960004207 fentanyl citrate Drugs 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000002889 sympathetic effect Effects 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200001154 | 2000-07-31 | ||
| DKPA200001154 | 2000-07-31 | ||
| PCT/DK2001/000521 WO2002009707A1 (en) | 2000-07-31 | 2001-07-31 | Fentanyl composition for nasal administration |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007238844A Division JP2008044951A (ja) | 2000-07-31 | 2007-09-14 | 鼻内投与用フェンタニル組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004505052A JP2004505052A (ja) | 2004-02-19 |
| JP2004505052A5 true JP2004505052A5 (enExample) | 2007-03-29 |
| JP4898073B2 JP4898073B2 (ja) | 2012-03-14 |
Family
ID=8159630
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002515260A Expired - Lifetime JP4898073B2 (ja) | 2000-07-31 | 2001-07-31 | 鼻内投与用フェンタニル組成物 |
| JP2007238844A Pending JP2008044951A (ja) | 2000-07-31 | 2007-09-14 | 鼻内投与用フェンタニル組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007238844A Pending JP2008044951A (ja) | 2000-07-31 | 2007-09-14 | 鼻内投与用フェンタニル組成物 |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US8017627B2 (enExample) |
| EP (3) | EP2255806A3 (enExample) |
| JP (2) | JP4898073B2 (enExample) |
| KR (2) | KR20080053423A (enExample) |
| CN (2) | CN101181241A (enExample) |
| AT (1) | ATE388705T1 (enExample) |
| AU (2) | AU2001281746C1 (enExample) |
| CA (1) | CA2417727C (enExample) |
| CY (2) | CY1107405T1 (enExample) |
| DE (2) | DE60133203T3 (enExample) |
| DK (2) | DK1307194T4 (enExample) |
| EA (1) | EA006384B1 (enExample) |
| EE (1) | EE05420B1 (enExample) |
| ES (2) | ES2427976T5 (enExample) |
| IL (2) | IL154041A0 (enExample) |
| IS (1) | IS2803B (enExample) |
| NO (2) | NO330565B1 (enExample) |
| NZ (1) | NZ524396A (enExample) |
| PL (1) | PL207845B1 (enExample) |
| PT (2) | PT1307194E (enExample) |
| SI (2) | SI1307194T2 (enExample) |
| UA (2) | UA77398C2 (enExample) |
| WO (1) | WO2002009707A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040115133A1 (en) * | 2000-05-10 | 2004-06-17 | Wermeling Daniel P. | Intranasal opioid compositions |
| PT1307194E (pt) * | 2000-07-31 | 2008-05-27 | Nycomed Danmark Aps | Composição à base de fentanil para administração nasal |
| US20020106407A1 (en) * | 2000-12-11 | 2002-08-08 | Dennis Coleman | Method and apparatus for treating breakthrough pain |
| US20090281023A9 (en) * | 2001-06-04 | 2009-11-12 | Nobex Corporation | Mixtures Of Calcitonin Drug-Oligomer Conjugates And Methods Of Use In Pain Treatment |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| GB0210264D0 (en) * | 2002-05-03 | 2002-06-12 | Arakis Ltd | The treatment of pain and migraine headache |
| GB0300531D0 (en) | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
| GB0305579D0 (en) * | 2003-03-11 | 2003-04-16 | Dallas Burston Ltd | Pharmaceutical compositions |
| GB0315632D0 (en) | 2003-07-04 | 2003-08-13 | West Pharm Serv Drug Res Ltd | Pharmaceutical formulations |
| US20070053965A1 (en) * | 2005-02-25 | 2007-03-08 | Gruenenthal Gmbh | Kit comprising a plaster, optionally containing an active substance, and an agent that at least partially reduces skin irritation |
| US8252328B2 (en) * | 2006-01-06 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
| US9066847B2 (en) | 2007-01-05 | 2015-06-30 | Aceirx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
| US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
| US8202535B2 (en) * | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
| US8535714B2 (en) | 2006-01-06 | 2013-09-17 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
| US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
| US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
| US9289583B2 (en) | 2006-01-06 | 2016-03-22 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
| US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
| CA2650412C (en) * | 2006-04-13 | 2016-09-27 | Nupathe, Inc. | Transdermal methods and systems for the delivery of anti-migraine compounds |
| US10512644B2 (en) | 2007-03-12 | 2019-12-24 | Inheris Pharmaceuticals, Inc. | Oligomer-opioid agonist conjugates |
| US8173666B2 (en) | 2007-03-12 | 2012-05-08 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| WO2009070829A1 (en) * | 2007-12-05 | 2009-06-11 | Krius Pty Ltd | Non-aqueous oil-based fentanyl compositions for transmucosal administration |
| WO2009100383A2 (en) | 2008-02-07 | 2009-08-13 | University Of Washington | Circumferential aerosol device |
| GB2464282A (en) * | 2008-10-08 | 2010-04-14 | Archimedes Dev Ltd | A device for administering a dose of opioid analgesic |
| US8945592B2 (en) | 2008-11-21 | 2015-02-03 | Acelrx Pharmaceuticals, Inc. | Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same |
| DE102009001041A1 (de) * | 2009-02-20 | 2010-08-26 | Marien-Apotheke Fulda Ohg | Notfallset zur Herstellung eines Arzneimittels zur nasalen Anwendung von Opioiden bei Atemnot |
| WO2012024595A2 (en) | 2010-08-20 | 2012-02-23 | University Of Washington | Circumferential aerosol device for delivering drugs to olfactory epithelium and brain |
| RS55199B1 (sr) | 2011-02-04 | 2017-01-31 | Archimedes Dev Ltd | Poboljšana posuda |
| AU2012223160B2 (en) | 2011-03-03 | 2016-08-18 | Impel Pharmaceuticals Inc. | Nasal drug delivery device |
| AU2012253569B2 (en) | 2011-05-09 | 2018-02-15 | Impel Pharmaceuticals Inc. | Nozzles for nasal drug delivery |
| AT16553U1 (de) * | 2011-05-13 | 2020-01-15 | Euro Celtique Sa | Intranasale pharmazeutische Darreichungsformen umfassend Naloxon |
| EP2991713B1 (en) | 2013-04-28 | 2019-06-19 | Impel Neuropharma Inc. | Medical unit dose container |
| SG11201704797TA (en) | 2014-12-23 | 2017-07-28 | Acelrx Pharmaceuticals Inc | Systems, devices and methods for dispensing oral transmucosal dosage forms |
| EP3341059B1 (en) | 2015-09-10 | 2022-03-02 | Impel NeuroPharma Inc. | In-line nasal delivery device |
| CA3081680A1 (en) | 2017-11-21 | 2019-05-31 | Impel Neuropharma, Inc. | Intranasal device with inlet interface |
| JP7191099B2 (ja) | 2017-11-21 | 2022-12-16 | インペル ファーマシューティカルズ インコーポレイテッド | 浸漬管を備えた鼻腔内装置 |
| BR112020013744A8 (pt) | 2018-01-05 | 2022-10-18 | Impel Neuropharma Inc | Dispensação intranasal de di-hidroergotamina por dispositivo olfativo de precisão |
| CN111836615A (zh) | 2018-01-05 | 2020-10-27 | 英倍尔药业股份有限公司 | 通过精密鼻装置的奥氮平的鼻内递送 |
| KR20210034047A (ko) | 2018-07-19 | 2021-03-29 | 임펠 뉴로파마 인코포레이티드 | 파킨슨 병 치료를 위한 레보도파 및 도파 데카르복실라아제 저해제의 기도 전달 |
| MX2021008082A (es) | 2019-01-03 | 2021-08-05 | Impel Pharmaceuticals Inc | Dispositivo de administracion de farmaco nasal. |
| AU2020277313A1 (en) | 2019-05-17 | 2022-01-20 | Impel Pharmaceuticals Inc. | Single-use nasal delivery device |
| US20230372327A1 (en) | 2020-10-15 | 2023-11-23 | Pharmbiotest Poland Sp. z o. o. | Pharmaceutical composition based on nalbuphine and/or its salts for nasal administration |
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|---|---|---|---|---|
| US4464378A (en) * | 1981-04-28 | 1984-08-07 | University Of Kentucky Research Foundation | Method of administering narcotic antagonists and analgesics and novel dosage forms containing same |
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| US4588580B2 (en) | 1984-07-23 | 1999-02-16 | Alaz Corp | Transdermal administration of fentanyl and device therefor |
| FR2568773B1 (fr) | 1984-08-10 | 1989-03-03 | Sandoz Lab | Nouvelles compositions pharmaceutiques administrables par voie nasale |
| US4806341A (en) * | 1985-02-25 | 1989-02-21 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration |
| US5122127A (en) * | 1985-05-01 | 1992-06-16 | University Of Utah | Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues |
| ZA875317B (en) * | 1986-08-01 | 1988-01-25 | Warner-Lambert Company | Transdermal compositions |
| US4916142A (en) | 1987-02-02 | 1990-04-10 | Boc, Inc. | N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics |
| GB8900267D0 (en) * | 1989-01-06 | 1989-03-08 | Riker Laboratories Inc | Narcotic analgesic formulations and apparatus containing same |
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| IE960375A1 (en) | 1995-06-05 | 1996-12-11 | Alza Corp | Device for transdermal electrotransport delivery of fentanyl¹and sufentanil |
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| PT1307194E (pt) | 2000-07-31 | 2008-05-27 | Nycomed Danmark Aps | Composição à base de fentanil para administração nasal |
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| NO2180844T3 (enExample) | 2007-08-02 | 2018-07-21 | ||
| WO2009070829A1 (en) | 2007-12-05 | 2009-06-11 | Krius Pty Ltd | Non-aqueous oil-based fentanyl compositions for transmucosal administration |
-
2001
- 2001-07-31 PT PT01960190T patent/PT1307194E/pt unknown
- 2001-07-31 JP JP2002515260A patent/JP4898073B2/ja not_active Expired - Lifetime
- 2001-07-31 CA CA002417727A patent/CA2417727C/en not_active Expired - Lifetime
- 2001-07-31 EA EA200300201A patent/EA006384B1/ru not_active IP Right Cessation
- 2001-07-31 AU AU2001281746A patent/AU2001281746C1/en active Active
- 2001-07-31 AT AT01960190T patent/ATE388705T1/de active
- 2001-07-31 IL IL15404101A patent/IL154041A0/xx unknown
- 2001-07-31 AU AU8174601A patent/AU8174601A/xx active Pending
- 2001-07-31 KR KR1020087013535A patent/KR20080053423A/ko not_active Withdrawn
- 2001-07-31 EP EP10176843A patent/EP2255806A3/en not_active Withdrawn
- 2001-07-31 EE EEP200300050A patent/EE05420B1/xx unknown
- 2001-07-31 NZ NZ524396A patent/NZ524396A/en not_active IP Right Cessation
- 2001-07-31 EP EP05078002.2A patent/EP1642578B2/en not_active Expired - Lifetime
- 2001-07-31 DE DE60133203T patent/DE60133203T3/de not_active Expired - Lifetime
- 2001-07-31 ES ES05078002T patent/ES2427976T5/es not_active Expired - Lifetime
- 2001-07-31 DK DK01960190.5T patent/DK1307194T4/da active
- 2001-07-31 PL PL365053A patent/PL207845B1/pl not_active IP Right Cessation
- 2001-07-31 SI SI200130827T patent/SI1307194T2/sl unknown
- 2001-07-31 WO PCT/DK2001/000521 patent/WO2002009707A1/en not_active Ceased
- 2001-07-31 PT PT50780022T patent/PT1642578E/pt unknown
- 2001-07-31 UA UA2003021772A patent/UA77398C2/uk unknown
- 2001-07-31 SI SI200131025T patent/SI1642578T2/sl unknown
- 2001-07-31 EP EP01960190A patent/EP1307194B2/en not_active Expired - Lifetime
- 2001-07-31 CN CNA2007101539372A patent/CN101181241A/zh active Pending
- 2001-07-31 ES ES01960190T patent/ES2302742T5/es not_active Expired - Lifetime
- 2001-07-31 KR KR1020037001578A patent/KR100888275B1/ko not_active Expired - Lifetime
- 2001-07-31 CN CNB018161634A patent/CN100346788C/zh not_active Expired - Lifetime
- 2001-07-31 DK DK05078002.2T patent/DK1642578T3/da active
- 2001-07-31 DE DE20122843U patent/DE20122843U1/de not_active Expired - Lifetime
- 2001-07-31 US US10/343,449 patent/US8017627B2/en not_active Expired - Lifetime
-
2003
- 2003-01-20 IL IL154041A patent/IL154041A/en active IP Right Grant
- 2003-01-24 NO NO20030365A patent/NO330565B1/no not_active IP Right Cessation
- 2003-01-28 IS IS6702A patent/IS2803B/is unknown
-
2006
- 2006-02-17 UA UAA200601709A patent/UA89755C2/ru unknown
-
2007
- 2007-01-24 US US11/656,970 patent/US8158651B2/en not_active Expired - Lifetime
- 2007-09-14 JP JP2007238844A patent/JP2008044951A/ja active Pending
-
2008
- 2008-04-14 CY CY20081100405T patent/CY1107405T1/el unknown
-
2011
- 2011-03-04 NO NO20110342A patent/NO333809B1/no not_active IP Right Cessation
- 2011-07-22 US US13/188,862 patent/US8653107B2/en not_active Expired - Fee Related
-
2013
- 2013-09-11 CY CY20131100788T patent/CY1114645T1/el unknown
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