JP2006516272A5 - - Google Patents
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- Publication number
- JP2006516272A5 JP2006516272A5 JP2006500187A JP2006500187A JP2006516272A5 JP 2006516272 A5 JP2006516272 A5 JP 2006516272A5 JP 2006500187 A JP2006500187 A JP 2006500187A JP 2006500187 A JP2006500187 A JP 2006500187A JP 2006516272 A5 JP2006516272 A5 JP 2006516272A5
- Authority
- JP
- Japan
- Prior art keywords
- fentanyl
- composition according
- composition
- pectin
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 27
- 229960002428 fentanyl Drugs 0.000 claims description 26
- 229920001277 pectin Polymers 0.000 claims description 17
- 239000001814 pectin Substances 0.000 claims description 17
- 235000010987 pectin Nutrition 0.000 claims description 17
- 150000003839 salts Chemical class 0.000 claims description 14
- 239000007864 aqueous solution Substances 0.000 claims description 9
- 208000002193 Pain Diseases 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 6
- 230000032050 esterification Effects 0.000 claims description 6
- 238000005886 esterification reaction Methods 0.000 claims description 6
- 229910021645 metal ion Inorganic materials 0.000 claims description 6
- 230000036470 plasma concentration Effects 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 208000000094 Chronic Pain Diseases 0.000 claims description 3
- 230000002265 prevention Effects 0.000 claims description 3
- IVLVTNPOHDFFCJ-UHFFFAOYSA-N fentanyl citrate Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 IVLVTNPOHDFFCJ-UHFFFAOYSA-N 0.000 claims 16
- 238000000034 method Methods 0.000 claims 3
- 239000007921 spray Substances 0.000 claims 2
- 229960004207 fentanyl citrate Drugs 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 description 11
- 241001465754 Metazoa Species 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 229910001424 calcium ion Inorganic materials 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 241000282412 Homo Species 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0300531.1A GB0300531D0 (en) | 2003-01-10 | 2003-01-10 | Pharmaceutical compositions |
| GB0300531.1 | 2003-01-10 | ||
| PCT/GB2004/000057 WO2004062561A2 (en) | 2003-01-10 | 2004-01-12 | Pharmaceutical compositions comprising fentanyl for intranasal delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006516272A JP2006516272A (ja) | 2006-06-29 |
| JP2006516272A5 true JP2006516272A5 (enExample) | 2011-07-28 |
| JP4827725B2 JP4827725B2 (ja) | 2011-11-30 |
Family
ID=9950919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500187A Expired - Fee Related JP4827725B2 (ja) | 2003-01-10 | 2004-01-12 | 医薬品組成物 |
Country Status (25)
| Country | Link |
|---|---|
| US (5) | US20040166067A1 (enExample) |
| EP (2) | EP1635783B1 (enExample) |
| JP (1) | JP4827725B2 (enExample) |
| KR (3) | KR101012148B1 (enExample) |
| CN (1) | CN100423709C (enExample) |
| AU (1) | AU2004204381B2 (enExample) |
| BR (1) | BRPI0406674B8 (enExample) |
| CA (1) | CA2511974C (enExample) |
| CY (1) | CY1115056T1 (enExample) |
| DK (1) | DK1635783T5 (enExample) |
| EA (1) | EA008500B1 (enExample) |
| ES (2) | ES2432119T3 (enExample) |
| FR (1) | FR14C0020I1 (enExample) |
| GB (1) | GB0300531D0 (enExample) |
| GE (1) | GEP20084340B (enExample) |
| IL (1) | IL169480A (enExample) |
| MX (1) | MXPA05007333A (enExample) |
| NO (1) | NO335127B1 (enExample) |
| NZ (1) | NZ541018A (enExample) |
| PL (1) | PL212950B1 (enExample) |
| PT (2) | PT1635783E (enExample) |
| SI (1) | SI1635783T1 (enExample) |
| UA (1) | UA85050C2 (enExample) |
| WO (1) | WO2004062561A2 (enExample) |
| ZA (1) | ZA200505274B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1307194E (pt) | 2000-07-31 | 2008-05-27 | Nycomed Danmark Aps | Composição à base de fentanil para administração nasal |
| US7666876B2 (en) * | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
| GB0300531D0 (en) | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
| GB0315632D0 (en) | 2003-07-04 | 2003-08-13 | West Pharm Serv Drug Res Ltd | Pharmaceutical formulations |
| US20050129679A1 (en) | 2003-12-15 | 2005-06-16 | Nastech Pharmaceutical Company Inc. | Method for opening tight junctions |
| EP2057982A1 (en) * | 2007-11-09 | 2009-05-13 | Archimedes Development Limited | Intranasal compositions |
| GB2464282A (en) * | 2008-10-08 | 2010-04-14 | Archimedes Dev Ltd | A device for administering a dose of opioid analgesic |
| CZ302789B6 (cs) | 2009-11-25 | 2011-11-09 | Zentiva, K. S. | Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva |
| KR20140017547A (ko) | 2011-02-04 | 2014-02-11 | 아르키메데스 디벨로프먼트 리미티드 | 개량된 용기 |
| SG194927A1 (en) | 2011-05-13 | 2013-12-30 | Euro Celtique Sa | Intranasal pharmaceutical dosage forms comprising naloxone |
| ES2748632T3 (es) | 2012-10-03 | 2020-03-17 | Proponent Biotech Gmbh | Composición farmacéutica que comprende ácido propiónico para uso en el tratamiento de infecciones víricas |
| KR102321172B1 (ko) | 2013-09-05 | 2021-11-05 | 에이비2 바이오 에스에이 | 염증성 질환에서 il-18 결합 단백질(ｉｌ-18ｂｐ) |
| US11135155B2 (en) | 2014-07-08 | 2021-10-05 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
| MX2017010919A (es) | 2015-03-05 | 2017-12-07 | Ab2 Bio Sa | Proteina de union il-18 (il-18bp) y anticuerpos en enfermedades inflamatorias. |
| US9650338B1 (en) | 2016-07-29 | 2017-05-16 | VDM Biochemicals, Inc. | Opioid antagonist compounds and methods of making and using |
| ES2968153T3 (es) * | 2017-01-11 | 2024-05-08 | Torrent Pharmaceuticals Ltd | Composición nasal de tapentadol |
| US11207309B2 (en) | 2019-07-19 | 2021-12-28 | Hikma Pharmaceuticals International Limited | Ready-to-administer fentanyl formulations |
| US11160799B2 (en) * | 2019-10-22 | 2021-11-02 | Cessatech A/S | Pediatric combination |
| CN111272860B (zh) | 2020-03-16 | 2022-11-25 | 中国检验检疫科学研究院 | 一种芬太尼类物质的小型便携式质谱现场快速检测方法 |
| EP4146174A1 (en) | 2020-05-06 | 2023-03-15 | AB2 Bio SA | Il-18 binding protein (il-18bp) in respiratory diseases |
| GB202007404D0 (en) | 2020-05-19 | 2020-07-01 | Nasser Syed Muhammad Tahir | Treatment for viral respiratory infections |
| EP3943097A1 (en) | 2020-07-24 | 2022-01-26 | AB2 Bio SA | Car-t cell therapy |
| WO2023067348A1 (en) | 2021-10-21 | 2023-04-27 | Biosirius Ltd | Treatment for virally-induced pneumonia |
| EP4486367A1 (en) | 2022-03-04 | 2025-01-08 | AB2 Bio SA | Il-18 binding protein (il-18bp) in the treatment of vexas |
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-
2003
- 2003-01-10 GB GBGB0300531.1A patent/GB0300531D0/en not_active Ceased
-
2004
- 2004-01-08 US US10/753,628 patent/US20040166067A1/en not_active Abandoned
- 2004-01-12 ES ES04701381T patent/ES2432119T3/es not_active Expired - Lifetime
- 2004-01-12 DK DK04701381.8T patent/DK1635783T5/da active
- 2004-01-12 PT PT47013818T patent/PT1635783E/pt unknown
- 2004-01-12 MX MXPA05007333A patent/MXPA05007333A/es active IP Right Grant
- 2004-01-12 BR BRPI0406674A patent/BRPI0406674B8/pt not_active IP Right Cessation
- 2004-01-12 PL PL377823A patent/PL212950B1/pl unknown
- 2004-01-12 UA UAA200507799A patent/UA85050C2/ru unknown
- 2004-01-12 EP EP04701381.8A patent/EP1635783B1/en not_active Expired - Lifetime
- 2004-01-12 AU AU2004204381A patent/AU2004204381B2/en active Active
- 2004-01-12 PT PT11185114T patent/PT2436375T/pt unknown
- 2004-01-12 WO PCT/GB2004/000057 patent/WO2004062561A2/en not_active Ceased
- 2004-01-12 NZ NZ541018A patent/NZ541018A/en not_active IP Right Cessation
- 2004-01-12 KR KR1020097010700A patent/KR101012148B1/ko not_active Expired - Lifetime
- 2004-01-12 CA CA2511974A patent/CA2511974C/en not_active Expired - Fee Related
- 2004-01-12 ES ES11185114T patent/ES2721899T3/es not_active Expired - Lifetime
- 2004-01-12 GE GEAP20048931A patent/GEP20084340B/en unknown
- 2004-01-12 EP EP11185114.3A patent/EP2436375B1/en not_active Expired - Lifetime
- 2004-01-12 KR KR1020057012821A patent/KR20050103275A/ko not_active Ceased
- 2004-01-12 JP JP2006500187A patent/JP4827725B2/ja not_active Expired - Fee Related
- 2004-01-12 CN CNB200480002000XA patent/CN100423709C/zh not_active Expired - Lifetime
- 2004-01-12 SI SI200432094T patent/SI1635783T1/sl unknown
- 2004-01-12 KR KR1020107021362A patent/KR20100118144A/ko not_active Abandoned
- 2004-01-12 EA EA200501105A patent/EA008500B1/ru not_active IP Right Cessation
-
2005
- 2005-06-24 NO NO20053119A patent/NO335127B1/no not_active IP Right Cessation
- 2005-06-29 IL IL169480A patent/IL169480A/en active IP Right Grant
- 2005-06-29 ZA ZA2005/05274A patent/ZA200505274B/en unknown
-
2008
- 2008-03-13 US US12/047,388 patent/US8216604B2/en not_active Expired - Fee Related
-
2012
- 2012-07-03 US US13/541,325 patent/US9078814B2/en not_active Expired - Fee Related
- 2012-07-03 US US13/541,314 patent/US8889176B2/en not_active Expired - Fee Related
-
2013
- 2013-12-04 CY CY20131101096T patent/CY1115056T1/el unknown
-
2014
- 2014-03-13 FR FR14C0020C patent/FR14C0020I1/fr active Active
-
2015
- 2015-06-23 US US14/747,289 patent/US9814705B2/en not_active Expired - Fee Related
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