JP2002524415A5 - - Google Patents
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- Publication number
- JP2002524415A5 JP2002524415A5 JP2000568493A JP2000568493A JP2002524415A5 JP 2002524415 A5 JP2002524415 A5 JP 2002524415A5 JP 2000568493 A JP2000568493 A JP 2000568493A JP 2000568493 A JP2000568493 A JP 2000568493A JP 2002524415 A5 JP2002524415 A5 JP 2002524415A5
- Authority
- JP
- Japan
- Prior art keywords
- nsaid
- milligrams
- pharmaceutical composition
- animal
- flurbiprofen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 17
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 16
- 239000008194 pharmaceutical composition Substances 0.000 description 11
- SYTBZMRGLBWNTM-SNVBAGLBSA-N (R)-flurbiprofen Chemical compound FC1=CC([C@H](C(O)=O)C)=CC=C1C1=CC=CC=C1 SYTBZMRGLBWNTM-SNVBAGLBSA-N 0.000 description 6
- 239000002552 dosage form Substances 0.000 description 4
- DKYWVDODHFEZIM-LLVKDONJSA-N (2r)-2-(3-benzoylphenyl)propanoic acid Chemical compound OC(=O)[C@H](C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-LLVKDONJSA-N 0.000 description 3
- NNYBQONXHNTVIJ-QGZVFWFLSA-N (R)-etodolac Chemical compound C1CO[C@](CC)(CC(O)=O)C2=C1C(C=CC=C1CC)=C1N2 NNYBQONXHNTVIJ-QGZVFWFLSA-N 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- -1 R-ketorolac Chemical compound 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 229960005430 benoxaprofen Drugs 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 229960003184 carprofen Drugs 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 229960004752 ketorolac Drugs 0.000 description 3
- 229960004492 suprofen Drugs 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14639598A | 1998-09-03 | 1998-09-03 | |
| US09/146,395 | 1998-09-03 | ||
| PCT/US1999/020261 WO2000013684A2 (en) | 1998-09-03 | 1999-09-03 | Pharmaceutical composition and method for treatment of inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002524415A JP2002524415A (ja) | 2002-08-06 |
| JP2002524415A5 true JP2002524415A5 (enExample) | 2006-10-19 |
Family
ID=22517175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000568493A Pending JP2002524415A (ja) | 1998-09-03 | 1999-09-03 | 炎症を治療するための医薬組成物及び方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6472433B2 (enExample) |
| EP (1) | EP1143958B8 (enExample) |
| JP (1) | JP2002524415A (enExample) |
| CN (1) | CN1391470A (enExample) |
| AT (1) | ATE353010T1 (enExample) |
| AU (1) | AU6026099A (enExample) |
| CA (1) | CA2342628C (enExample) |
| CY (1) | CY1106541T1 (enExample) |
| DE (1) | DE69933049T2 (enExample) |
| DK (1) | DK1143958T3 (enExample) |
| ES (1) | ES2281981T3 (enExample) |
| PT (1) | PT1143958E (enExample) |
| WO (1) | WO2000013684A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
| HRP20010309B1 (en) | 1998-12-23 | 2005-06-30 | Idea Ag | Improved formulation for topical non-invasive application in vivo |
| DE69901377T2 (de) | 1999-01-27 | 2003-01-02 | Idea Ag | Nichtinvasive Impfung durch die Haut |
| ATE216223T1 (de) | 1999-01-27 | 2002-05-15 | Idea Ag | Transnasaler transport bzw. impfung mit hochadaptierbaren trägern |
| DE19907895A1 (de) * | 1999-02-24 | 2000-11-16 | Paz Arzneimittelentwicklung | Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen bei Mensch und Tier, welche durch die Hemmung der Aktivierung von NF-kB therapeutisch beeinflußt werden können |
| WO2001001962A1 (en) | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
| DE60016191T2 (de) | 1999-12-08 | 2005-12-22 | Pharmacia Corp., Chicago | Cyclooxygenase-2 hemmer enthaltende zusammensetzungen mit schnellem wirkungseintritt |
| US20060004086A1 (en) * | 2000-04-13 | 2006-01-05 | Mayo Foundation For Medical Education And Research | Method of reducing Abeta42 and treating diseases |
| AU5702201A (en) * | 2000-04-13 | 2001-10-30 | Mayo Foundation | Abeta<sub>42</sub> lowering agents |
| DE10047319A1 (de) * | 2000-09-25 | 2002-04-18 | Paz Arzneimittelentwicklung | Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen, welche durch die Hemmung der Aktivierung des nukleären Transkriptionsfaktors AP-1 therapeutisch beeinflußt werden können |
| US20040077604A1 (en) * | 2001-12-19 | 2004-04-22 | Lenard Lichtenberger | Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity |
| US20030027867A1 (en) * | 2001-06-29 | 2003-02-06 | Myriad Genetics, Incorporated | Use of R-NSAID compounds for anti-HIV treatment |
| US20030143165A1 (en) * | 2002-01-25 | 2003-07-31 | Allan Evans | NSAID-containing topical formulations that demonstrate chemopreventive activity |
| US7473432B2 (en) * | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
| EP1603548A4 (en) * | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | METHOD AND COMPOSITION FOR THE TREATMENT OF NEURODEEGENERATIVE DISEASES |
| US20050042284A1 (en) * | 2003-07-11 | 2005-02-24 | Myriad Genetics, Incorporated | Pharmaceutical methods, dosing regimes and dosage forms for the treatment of Alzheimer's disease |
| KR20070086045A (ko) * | 2004-11-12 | 2007-08-27 | 이데아 아게 | 피부 상태 치료에서의 확대된 표면 집합체 |
| US20070042034A1 (en) * | 2005-07-22 | 2007-02-22 | Myriad Genetics, Incorporated | High drug load formulations and dosage forms |
| US9125899B1 (en) | 2010-06-17 | 2015-09-08 | Stc.Unm | Modulators of GTPases and their use |
| EP2468270A1 (en) | 2010-12-21 | 2012-06-27 | GALENpharma GmbH | (R)-2-(3-fluoro-4-phenylphenyl)propionic acid for use in the treatment of skin diseases |
| US9346803B2 (en) | 2011-10-17 | 2016-05-24 | Vanderbilt University | Indomethacin analogs for the treatment of castrate-resistant prostate cancer |
| US20150183737A1 (en) * | 2012-07-20 | 2015-07-02 | Vanderbilt University | Compositions and methods for substrate-selective inhibition of endocannabinoid oxygenation |
| US9012402B1 (en) | 2014-06-11 | 2015-04-21 | James Blanchard | Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation |
| US10821075B1 (en) | 2017-07-12 | 2020-11-03 | James Blanchard | Compositions for topical application of a medicaments onto a mammalian body surface |
| CN113712960B (zh) * | 2021-09-23 | 2023-04-07 | 南京医科大学 | R-酮咯酸在防治主动脉夹层和主动脉瘤中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4028906A1 (de) | 1990-09-12 | 1992-03-19 | Paz Arzneimittelentwicklung | Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen |
| US5331000A (en) * | 1992-03-09 | 1994-07-19 | Sepracor Inc. | Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen |
| DE4319438C1 (de) * | 1993-06-11 | 1994-06-01 | Gerd Dr Dr Geislinger | Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren |
| US6160018A (en) * | 1995-03-13 | 2000-12-12 | Loma Linda University Medical Center | Prophylactic composition and method for alzheimer's Disease |
| IT1298214B1 (it) | 1998-01-28 | 1999-12-20 | Dompe Spa | Sali dell'acido (r) 2-(3-benzoilfenil) propionico e loro composizioni farmaceutiche. |
-
1999
- 1999-09-03 PT PT99968626T patent/PT1143958E/pt unknown
- 1999-09-03 CN CN99811438A patent/CN1391470A/zh active Pending
- 1999-09-03 DK DK99968626T patent/DK1143958T3/da active
- 1999-09-03 JP JP2000568493A patent/JP2002524415A/ja active Pending
- 1999-09-03 DE DE69933049T patent/DE69933049T2/de not_active Revoked
- 1999-09-03 ES ES99968626T patent/ES2281981T3/es not_active Expired - Lifetime
- 1999-09-03 WO PCT/US1999/020261 patent/WO2000013684A2/en not_active Ceased
- 1999-09-03 AU AU60260/99A patent/AU6026099A/en not_active Abandoned
- 1999-09-03 CA CA002342628A patent/CA2342628C/en not_active Expired - Fee Related
- 1999-09-03 EP EP99968626A patent/EP1143958B8/en not_active Revoked
- 1999-09-03 AT AT99968626T patent/ATE353010T1/de not_active IP Right Cessation
-
2001
- 2001-03-01 US US09/797,022 patent/US6472433B2/en not_active Expired - Fee Related
-
2007
- 2007-04-26 CY CY20071100559T patent/CY1106541T1/el unknown
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