JP2001510795A5 - - Google Patents
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- Publication number
- JP2001510795A5 JP2001510795A5 JP2000503831A JP2000503831A JP2001510795A5 JP 2001510795 A5 JP2001510795 A5 JP 2001510795A5 JP 2000503831 A JP2000503831 A JP 2000503831A JP 2000503831 A JP2000503831 A JP 2000503831A JP 2001510795 A5 JP2001510795 A5 JP 2001510795A5
- Authority
- JP
- Japan
- Prior art keywords
- levobupivacaine
- surgery
- composition
- composition according
- dosage formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- LEBVLXFERQHONN-INIZCTEOSA-N levobupivacaine Chemical compound CCCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-INIZCTEOSA-N 0.000 description 15
- 229960004288 levobupivacaine Drugs 0.000 description 15
- 239000000203 mixture Substances 0.000 description 13
- 238000001356 surgical procedure Methods 0.000 description 6
- 238000009472 formulation Methods 0.000 description 3
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000007486 appendectomy Methods 0.000 description 1
- 229960003150 bupivacaine Drugs 0.000 description 1
- 238000002316 cosmetic surgery Methods 0.000 description 1
- 229960001985 dextromethorphan Drugs 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 238000002297 emergency surgery Methods 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 238000002682 general surgery Methods 0.000 description 1
- 238000009802 hysterectomy Methods 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 238000007483 tonsillectomy Methods 0.000 description 1
- 238000007631 vascular surgery Methods 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9715462.9A GB9715462D0 (en) | 1997-07-22 | 1997-07-22 | levobupivacaine and its use |
| GB9715462.9 | 1997-07-22 | ||
| GBGB9722022.2A GB9722022D0 (en) | 1997-10-17 | 1997-10-17 | Levobupivacaine and its use |
| GB9722022.2 | 1997-10-17 | ||
| GB9810427.6 | 1998-05-14 | ||
| GBGB9810427.6A GB9810427D0 (en) | 1998-05-14 | 1998-05-14 | Levobupivacaine and its use |
| PCT/GB1998/002170 WO1999004772A2 (en) | 1997-07-22 | 1998-07-21 | Use of levobupivacaine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001510795A JP2001510795A (ja) | 2001-08-07 |
| JP2001510795A5 true JP2001510795A5 (enExample) | 2006-01-05 |
Family
ID=27268945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000503831A Pending JP2001510795A (ja) | 1997-07-22 | 1998-07-21 | レボブピバカインとその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6069155A (enExample) |
| EP (1) | EP0998287B1 (enExample) |
| JP (1) | JP2001510795A (enExample) |
| AT (1) | ATE239474T1 (enExample) |
| AU (1) | AU739510B2 (enExample) |
| BR (1) | BR9802537A (enExample) |
| CA (1) | CA2294921C (enExample) |
| DE (1) | DE69814394T2 (enExample) |
| DK (1) | DK0998287T3 (enExample) |
| ES (1) | ES2198731T3 (enExample) |
| PT (1) | PT998287E (enExample) |
| WO (1) | WO1999004772A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376754B1 (en) * | 1997-03-07 | 2002-04-23 | Asgrow Seed Company | Plants having resistance to multiple herbicides and its use |
| AU752802C (en) | 1997-11-14 | 2006-04-13 | Pacira Pharmaceuticals, Inc. | Production of multivesicular liposomes |
| WO2000003660A1 (en) | 1998-07-17 | 2000-01-27 | Skyepharma, Inc. | Biodegradable compositions for the controlled release of encapsulated substances |
| WO2001070322A1 (en) * | 2000-03-24 | 2001-09-27 | Stephen Brushey | Anesthesia conduction catheter |
| US7805188B2 (en) * | 2000-03-24 | 2010-09-28 | Micor, Inc. | Anesthesia conduction catheter for delivery of electrical stimulus |
| BR0002246A (pt) * | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| WO2002096368A2 (en) * | 2001-05-31 | 2002-12-05 | Skyepharma Inc. | Encapsulation of nanosuspensions in liposomes and microspheres |
| US20070196415A1 (en) * | 2002-11-14 | 2007-08-23 | Guohua Chen | Depot compositions with multiple drug release rate controls and uses thereof |
| AU2002359407B2 (en) * | 2001-11-14 | 2008-02-28 | Durect Corporation | Catheter injectable depot compositions and uses thereof |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| CN1684663A (zh) | 2002-07-31 | 2005-10-19 | 阿尔萨公司 | 可注射的多模式聚合物储库组合物以及其用途 |
| WO2004012703A1 (en) * | 2002-07-31 | 2004-02-12 | Alza Corporation | Injectable depot compositions and uses thereof |
| WO2004060147A2 (en) * | 2002-12-31 | 2004-07-22 | The Board Of Trustees Of The University Of Illinois | Tissue and organ preservation, protection and resuscitation |
| US20060142234A1 (en) * | 2004-12-23 | 2006-06-29 | Guohua Chen | Injectable non-aqueous suspension |
| WO2015088990A1 (en) | 2013-12-09 | 2015-06-18 | Durect Corporation | Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same |
| WO2021146215A1 (en) | 2020-01-13 | 2021-07-22 | Durect Corporation | Sustained release drug delivery systems with reduced impurities and related methods |
| CA3203561A1 (en) | 2021-01-12 | 2022-07-21 | Adrian Neil Verity | Sustained release drug delivery systems and related methods |
| US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12151024B2 (en) | 2021-01-22 | 2024-11-26 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12285419B2 (en) | 2021-10-14 | 2025-04-29 | Pacira Pharmaceuticals, Inc. | Bupivacaine multivesicular liposome formulations and uses thereof |
| US12070454B1 (en) | 2022-05-05 | 2024-08-27 | Pfof Llc | Anesthetic nerve block and method |
| CN119677554A (zh) | 2022-05-05 | 2025-03-21 | 普络夫有限责任公司 | 麻醉神经阻滞和方法 |
| US12156940B1 (en) | 2024-05-20 | 2024-12-03 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12251472B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12280149B1 (en) | 2024-05-20 | 2025-04-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4695576A (en) * | 1984-07-09 | 1987-09-22 | Astra Lake Medel Aktiebolag | L-N-n-propylpipecolic acid-2,6-xylidide |
| AU694453B2 (en) * | 1993-10-13 | 1998-07-23 | Darwin Discovery Limited | Analgesic agent and its use |
| GB9321061D0 (en) * | 1993-10-13 | 1993-12-01 | Chiroscience Ltd | Analgestic agent and its use |
| US5849763A (en) * | 1993-10-13 | 1998-12-15 | Darwin Discovery Limited | Use of levobupivacaine as an anesthetic agent |
| CA2216583C (en) * | 1995-04-13 | 2007-10-30 | Chiroscience Limited | Levobupivacaine and its use as an anaesthetic in pregnant women |
| GB9704352D0 (en) * | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
-
1998
- 1998-07-21 AT AT98935176T patent/ATE239474T1/de active
- 1998-07-21 EP EP98935176A patent/EP0998287B1/en not_active Expired - Lifetime
- 1998-07-21 ES ES98935176T patent/ES2198731T3/es not_active Expired - Lifetime
- 1998-07-21 BR BR9802537A patent/BR9802537A/pt not_active Application Discontinuation
- 1998-07-21 WO PCT/GB1998/002170 patent/WO1999004772A2/en not_active Ceased
- 1998-07-21 AU AU84528/98A patent/AU739510B2/en not_active Expired
- 1998-07-21 DE DE69814394T patent/DE69814394T2/de not_active Expired - Lifetime
- 1998-07-21 JP JP2000503831A patent/JP2001510795A/ja active Pending
- 1998-07-21 PT PT98935176T patent/PT998287E/pt unknown
- 1998-07-21 DK DK98935176T patent/DK0998287T3/da active
- 1998-07-21 CA CA002294921A patent/CA2294921C/en not_active Expired - Lifetime
- 1998-07-22 US US09/120,822 patent/US6069155A/en not_active Expired - Lifetime
-
2001
- 2001-10-01 US US09/969,412 patent/US6514994B2/en not_active Expired - Fee Related
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