AU739510B2 - Levobupivacaine and its use - Google Patents

Levobupivacaine and its use Download PDF

Info

Publication number
AU739510B2
AU739510B2 AU84528/98A AU8452898A AU739510B2 AU 739510 B2 AU739510 B2 AU 739510B2 AU 84528/98 A AU84528/98 A AU 84528/98A AU 8452898 A AU8452898 A AU 8452898A AU 739510 B2 AU739510 B2 AU 739510B2
Authority
AU
Australia
Prior art keywords
levobupivacaine
surgery
bupivacaine
major
dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU84528/98A
Other languages
English (en)
Other versions
AU8452898A (en
Inventor
Lawrence E. Mather
Andrew John Mcglashan Richards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9715462.9A external-priority patent/GB9715462D0/en
Priority claimed from GBGB9722022.2A external-priority patent/GB9722022D0/en
Priority claimed from GBGB9810427.6A external-priority patent/GB9810427D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of AU8452898A publication Critical patent/AU8452898A/en
Application granted granted Critical
Publication of AU739510B2 publication Critical patent/AU739510B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU84528/98A 1997-07-22 1998-07-21 Levobupivacaine and its use Expired AU739510B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9715462.9A GB9715462D0 (en) 1997-07-22 1997-07-22 levobupivacaine and its use
GB9715462 1997-07-22
GBGB9722022.2A GB9722022D0 (en) 1997-10-17 1997-10-17 Levobupivacaine and its use
GB9722022 1997-10-17
GBGB9810427.6A GB9810427D0 (en) 1998-05-14 1998-05-14 Levobupivacaine and its use
GB9810427 1998-05-14
PCT/GB1998/002170 WO1999004772A2 (en) 1997-07-22 1998-07-21 Use of levobupivacaine

Publications (2)

Publication Number Publication Date
AU8452898A AU8452898A (en) 1999-02-16
AU739510B2 true AU739510B2 (en) 2001-10-11

Family

ID=27268945

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84528/98A Expired AU739510B2 (en) 1997-07-22 1998-07-21 Levobupivacaine and its use

Country Status (12)

Country Link
US (2) US6069155A (enExample)
EP (1) EP0998287B1 (enExample)
JP (1) JP2001510795A (enExample)
AT (1) ATE239474T1 (enExample)
AU (1) AU739510B2 (enExample)
BR (1) BR9802537A (enExample)
CA (1) CA2294921C (enExample)
DE (1) DE69814394T2 (enExample)
DK (1) DK0998287T3 (enExample)
ES (1) ES2198731T3 (enExample)
PT (1) PT998287E (enExample)
WO (1) WO1999004772A2 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376754B1 (en) * 1997-03-07 2002-04-23 Asgrow Seed Company Plants having resistance to multiple herbicides and its use
AU752802C (en) 1997-11-14 2006-04-13 Pacira Pharmaceuticals, Inc. Production of multivesicular liposomes
WO2000003660A1 (en) 1998-07-17 2000-01-27 Skyepharma, Inc. Biodegradable compositions for the controlled release of encapsulated substances
WO2001070322A1 (en) * 2000-03-24 2001-09-27 Stephen Brushey Anesthesia conduction catheter
US7805188B2 (en) * 2000-03-24 2010-09-28 Micor, Inc. Anesthesia conduction catheter for delivery of electrical stimulus
BR0002246A (pt) * 2000-04-06 2003-04-15 Cristalia Prod Quimicos Farm Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis
WO2002096368A2 (en) * 2001-05-31 2002-12-05 Skyepharma Inc. Encapsulation of nanosuspensions in liposomes and microspheres
US20070196415A1 (en) * 2002-11-14 2007-08-23 Guohua Chen Depot compositions with multiple drug release rate controls and uses thereof
AU2002359407B2 (en) * 2001-11-14 2008-02-28 Durect Corporation Catheter injectable depot compositions and uses thereof
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
CN1684663A (zh) 2002-07-31 2005-10-19 阿尔萨公司 可注射的多模式聚合物储库组合物以及其用途
WO2004012703A1 (en) * 2002-07-31 2004-02-12 Alza Corporation Injectable depot compositions and uses thereof
WO2004060147A2 (en) * 2002-12-31 2004-07-22 The Board Of Trustees Of The University Of Illinois Tissue and organ preservation, protection and resuscitation
US20060142234A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
WO2015088990A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en) 2021-01-22 2024-11-26 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12285419B2 (en) 2021-10-14 2025-04-29 Pacira Pharmaceuticals, Inc. Bupivacaine multivesicular liposome formulations and uses thereof
US12070454B1 (en) 2022-05-05 2024-08-27 Pfof Llc Anesthetic nerve block and method
CN119677554A (zh) 2022-05-05 2025-03-21 普络夫有限责任公司 麻醉神经阻滞和方法
US12156940B1 (en) 2024-05-20 2024-12-03 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12251472B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12280149B1 (en) 2024-05-20 2025-04-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010277A1 (en) * 1993-10-13 1995-04-20 Chiroscience Limited Analgesic agent and its use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide
GB9321061D0 (en) * 1993-10-13 1993-12-01 Chiroscience Ltd Analgestic agent and its use
US5849763A (en) * 1993-10-13 1998-12-15 Darwin Discovery Limited Use of levobupivacaine as an anesthetic agent
CA2216583C (en) * 1995-04-13 2007-10-30 Chiroscience Limited Levobupivacaine and its use as an anaesthetic in pregnant women
GB9704352D0 (en) * 1997-03-03 1997-04-23 Chiroscience Ltd Levobupivacaine and its use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010277A1 (en) * 1993-10-13 1995-04-20 Chiroscience Limited Analgesic agent and its use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXP. OPIN. INVEST. DRUGS VOL 3, PAGES 1209-1212, 1994 *
REGIONAL ANAESTHESIA, VOL 14, PAGES 311-316, 1992 *

Also Published As

Publication number Publication date
DE69814394T2 (de) 2004-03-11
PT998287E (pt) 2003-09-30
JP2001510795A (ja) 2001-08-07
ES2198731T3 (es) 2004-02-01
US6514994B2 (en) 2003-02-04
EP0998287B1 (en) 2003-05-07
DK0998287T3 (da) 2003-09-01
AU8452898A (en) 1999-02-16
EP0998287A2 (en) 2000-05-10
US6069155A (en) 2000-05-30
US20020016338A1 (en) 2002-02-07
CA2294921A1 (en) 1999-02-04
WO1999004772A2 (en) 1999-02-04
WO1999004772A3 (en) 1999-04-08
DE69814394D1 (de) 2003-06-12
CA2294921C (en) 2009-04-07
ATE239474T1 (de) 2003-05-15
BR9802537A (pt) 1999-07-20

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired