JP2004504379A5 - - Google Patents

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Publication number
JP2004504379A5
JP2004504379A5 JP2002514092A JP2002514092A JP2004504379A5 JP 2004504379 A5 JP2004504379 A5 JP 2004504379A5 JP 2002514092 A JP2002514092 A JP 2002514092A JP 2002514092 A JP2002514092 A JP 2002514092A JP 2004504379 A5 JP2004504379 A5 JP 2004504379A5
Authority
JP
Japan
Prior art keywords
pyrrolidine
carboxylic acid
mercapto
alkyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002514092A
Other languages
English (en)
Japanese (ja)
Other versions
JP3983663B2 (ja
JP2004504379A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2001/007951 external-priority patent/WO2002008185A1/en
Publication of JP2004504379A publication Critical patent/JP2004504379A/ja
Publication of JP2004504379A5 publication Critical patent/JP2004504379A5/ja
Application granted granted Critical
Publication of JP3983663B2 publication Critical patent/JP3983663B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2002514092A 2000-07-19 2001-07-10 メタロプロテアーゼインヒビターとしてのピロリジン誘導体 Expired - Lifetime JP3983663B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00114949 2000-07-19
PCT/EP2001/007951 WO2002008185A1 (en) 2000-07-19 2001-07-10 Pyrrolidine derivatives as metalloprotease inhibitors

Publications (3)

Publication Number Publication Date
JP2004504379A JP2004504379A (ja) 2004-02-12
JP2004504379A5 true JP2004504379A5 (enExample) 2005-02-24
JP3983663B2 JP3983663B2 (ja) 2007-09-26

Family

ID=8169226

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002514092A Expired - Lifetime JP3983663B2 (ja) 2000-07-19 2001-07-10 メタロプロテアーゼインヒビターとしてのピロリジン誘導体

Country Status (15)

Country Link
US (3) US20020040146A1 (enExample)
EP (1) EP1303486A1 (enExample)
JP (1) JP3983663B2 (enExample)
KR (1) KR100613196B1 (enExample)
CN (1) CN100406439C (enExample)
AR (1) AR037990A1 (enExample)
AU (2) AU7847901A (enExample)
BR (1) BR0112655A (enExample)
CA (1) CA2415740A1 (enExample)
MX (1) MXPA03000368A (enExample)
PA (1) PA8522301A1 (enExample)
PE (1) PE20020333A1 (enExample)
UY (1) UY26846A1 (enExample)
WO (1) WO2002008185A1 (enExample)
ZA (1) ZA200300170B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100613196B1 (ko) * 2000-07-19 2006-08-18 에프. 호프만-라 로슈 아게 메탈로프로테아제 억제제로서의 피롤리딘 유도체
US7405234B2 (en) * 2002-05-17 2008-07-29 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
EA010267B1 (ru) 2002-10-07 2008-06-30 Те Риджентс Оф Те Юниверсити Оф Калифорния Модуляция тревоги через блокаду гидролиза анандамида
US7388027B2 (en) * 2004-03-04 2008-06-17 Bristol-Myers Squibb Company Bicyclic compounds as modulators of androgen receptor function and method
CN101376656A (zh) * 2007-08-30 2009-03-04 山东轩竹医药科技有限公司 培南衍生物
JP2011517313A (ja) 2007-12-11 2011-06-02 ビアメト ファーマシューティカルズ，インク． 金属結合部分を標的化部分と組み合わせて使用する金属酵素阻害剤
WO2010028051A2 (en) * 2008-09-03 2010-03-11 Florida State University Research Foundation, Inc. Substituted heterocyclic mercaptosulfonamide metalloprotease inhibitors
EP3316877B1 (en) 2015-07-02 2019-10-30 Horizon Orphan LLC Ado-resistant cysteamine analogs and uses thereof
EP4324329A3 (en) * 2018-01-17 2024-04-17 Migal Galilee Research Institute Ltd. New methionine metabolic pathway inhibitors
CN111825582B (zh) * 2020-08-12 2022-04-08 江西理工大学 一种以芳基磺酰氯为硫源合成β-硫代羰基化合物的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1281720C (en) * 1984-11-08 1991-03-19 Makoto Sunagawa Carbapenem compounds and production thereof
US4925838A (en) * 1988-03-18 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
US5317016A (en) * 1991-08-20 1994-05-31 Shionogi Seiyaku Kabushiki Kaisha Pyrrolidylthiocarbapenem derivative
GB9301276D0 (en) * 1993-01-22 1993-03-17 Fujisawa Pharmaceutical Co Bicyclic compounds and their preparation
EP0747381B1 (en) * 1994-02-25 2001-10-31 Banyu Pharmaceutical Co., Ltd. Carbapenem derivative
NZ503383A (en) * 1996-02-13 2002-02-01 Abbott Lab Method for contracting non-vascular smooth muscle using ethyl 2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-4,5-dihydro-3H-pyrrole-3-carboxlylate
ATE226193T1 (de) * 1996-08-28 2002-11-15 Procter & Gamble Substituierte zyklische amine als metalloproteaseinhibitoren
BR9712792A (pt) * 1996-08-28 1999-12-14 Procter & Gamble Inibidores de metaloprotease bidentada.
CN1620433A (zh) * 2000-07-19 2005-05-25 霍夫曼-拉罗奇有限公司 作为内皮肽转化酶抑制剂的吡咯烷衍生物
KR100613196B1 (ko) * 2000-07-19 2006-08-18 에프. 호프만-라 로슈 아게 메탈로프로테아제 억제제로서의 피롤리딘 유도체

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