JP2004504379A5 - - Google Patents
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- Publication number
- JP2004504379A5 JP2004504379A5 JP2002514092A JP2002514092A JP2004504379A5 JP 2004504379 A5 JP2004504379 A5 JP 2004504379A5 JP 2002514092 A JP2002514092 A JP 2002514092A JP 2002514092 A JP2002514092 A JP 2002514092A JP 2004504379 A5 JP2004504379 A5 JP 2004504379A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrrolidine
- carboxylic acid
- mercapto
- alkyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00114949 | 2000-07-19 | ||
| PCT/EP2001/007951 WO2002008185A1 (en) | 2000-07-19 | 2001-07-10 | Pyrrolidine derivatives as metalloprotease inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004504379A JP2004504379A (ja) | 2004-02-12 |
| JP2004504379A5 true JP2004504379A5 (enExample) | 2005-02-24 |
| JP3983663B2 JP3983663B2 (ja) | 2007-09-26 |
Family
ID=8169226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002514092A Expired - Lifetime JP3983663B2 (ja) | 2000-07-19 | 2001-07-10 | メタロプロテアーゼインヒビターとしてのピロリジン誘導体 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20020040146A1 (enExample) |
| EP (1) | EP1303486A1 (enExample) |
| JP (1) | JP3983663B2 (enExample) |
| KR (1) | KR100613196B1 (enExample) |
| CN (1) | CN100406439C (enExample) |
| AR (1) | AR037990A1 (enExample) |
| AU (2) | AU7847901A (enExample) |
| BR (1) | BR0112655A (enExample) |
| CA (1) | CA2415740A1 (enExample) |
| MX (1) | MXPA03000368A (enExample) |
| PA (1) | PA8522301A1 (enExample) |
| PE (1) | PE20020333A1 (enExample) |
| UY (1) | UY26846A1 (enExample) |
| WO (1) | WO2002008185A1 (enExample) |
| ZA (1) | ZA200300170B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0112655A (pt) * | 2000-07-19 | 2003-06-24 | Hoffmann La Roche | Derivados de pirrolidino como inibidores de metaloproteases |
| US7405234B2 (en) * | 2002-05-17 | 2008-07-29 | Bristol-Myers Squibb Company | Bicyclic modulators of androgen receptor function |
| MXPA05003715A (es) | 2002-10-07 | 2005-09-30 | Univ California | Modulacion de ansiedad a traves de bloqueo de hidrolisis de anandamida. |
| US7388027B2 (en) * | 2004-03-04 | 2008-06-17 | Bristol-Myers Squibb Company | Bicyclic compounds as modulators of androgen receptor function and method |
| CN101376656A (zh) * | 2007-08-30 | 2009-03-04 | 山东轩竹医药科技有限公司 | 培南衍生物 |
| EP2234608A2 (en) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
| US8404866B2 (en) * | 2008-09-03 | 2013-03-26 | Florida State University Research Foundation | Substituted heterocyclic mercaptosulfonamide metalloprotease inhibitors |
| TWI759267B (zh) | 2015-07-02 | 2022-04-01 | 美商地平線罕見醫學製藥有限責任公司 | Ａｄｏ抗性半胱胺類似物及其用途 |
| EP3740466B1 (en) * | 2018-01-17 | 2024-03-06 | Migal Galilee Research Institute Ltd. | New methionine metabolic pathway inhibitors |
| CN111825582B (zh) * | 2020-08-12 | 2022-04-08 | 江西理工大学 | 一种以芳基磺酰氯为硫源合成β-硫代羰基化合物的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3579888D1 (de) * | 1984-11-08 | 1990-10-31 | Sumitomo Pharma | Carbapenemverbindungen und deren herstellung. |
| US4925838A (en) * | 1988-03-18 | 1990-05-15 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
| US5317016A (en) * | 1991-08-20 | 1994-05-31 | Shionogi Seiyaku Kabushiki Kaisha | Pyrrolidylthiocarbapenem derivative |
| GB9301276D0 (en) * | 1993-01-22 | 1993-03-17 | Fujisawa Pharmaceutical Co | Bicyclic compounds and their preparation |
| CA2184101C (en) * | 1994-02-25 | 2005-11-22 | Susumu Nakagawa | Carbapenem derivatives |
| HUP9902316A3 (en) * | 1996-02-13 | 2001-12-28 | Abbott Lab | 4-(benzo-1,3-dioxolyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists and pharmaceutical compositions containing them |
| BR9713465A (pt) * | 1996-08-28 | 2000-03-28 | Procter & Gamble | Inibidores metalotprotease de amina cìclica sibstituìda |
| BR9712792A (pt) * | 1996-08-28 | 1999-12-14 | Procter & Gamble | Inibidores de metaloprotease bidentada. |
| AU2001270627A1 (en) * | 2000-07-19 | 2002-01-30 | F. Hoffmann-La Roche Ag | Pyrrolidine derivatives as inhibitors of endothelin-converting enzyme |
| BR0112655A (pt) * | 2000-07-19 | 2003-06-24 | Hoffmann La Roche | Derivados de pirrolidino como inibidores de metaloproteases |
-
2001
- 2001-07-10 BR BR0112655-5A patent/BR0112655A/pt not_active IP Right Cessation
- 2001-07-10 EP EP01956523A patent/EP1303486A1/en not_active Withdrawn
- 2001-07-10 JP JP2002514092A patent/JP3983663B2/ja not_active Expired - Lifetime
- 2001-07-10 MX MXPA03000368A patent/MXPA03000368A/es not_active Application Discontinuation
- 2001-07-10 WO PCT/EP2001/007951 patent/WO2002008185A1/en not_active Ceased
- 2001-07-10 AU AU7847901A patent/AU7847901A/xx active Pending
- 2001-07-10 AU AU2001278479A patent/AU2001278479B2/en not_active Ceased
- 2001-07-10 KR KR1020037000790A patent/KR100613196B1/ko not_active Expired - Fee Related
- 2001-07-10 CN CNB018130534A patent/CN100406439C/zh not_active Expired - Fee Related
- 2001-07-10 CA CA002415740A patent/CA2415740A1/en not_active Abandoned
- 2001-07-16 PA PA20018522301A patent/PA8522301A1/es unknown
- 2001-07-17 UY UY26846A patent/UY26846A1/es not_active Application Discontinuation
- 2001-07-17 AR ARP010103415A patent/AR037990A1/es not_active Application Discontinuation
- 2001-07-17 PE PE2001000719A patent/PE20020333A1/es not_active Application Discontinuation
- 2001-07-17 US US09/906,980 patent/US20020040146A1/en not_active Abandoned
-
2003
- 2003-01-07 ZA ZA200300170A patent/ZA200300170B/en unknown
- 2003-02-25 US US10/373,622 patent/US6790860B2/en not_active Expired - Fee Related
-
2004
- 2004-06-30 US US10/881,427 patent/US7189756B2/en not_active Expired - Fee Related
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