|
US6900226B2
(en)
*
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
|
US7084156B2
(en)
*
|
2001-11-27 |
2006-08-01 |
Merck & Co., Inc. |
2-Aminoquinoline compounds
|
|
KR100659428B1
(ko)
*
|
2002-02-04 |
2006-12-19 |
에프. 호프만-라 로슈 아게 |
Ｎｐｙ 길항제로서의 퀴놀린 유도체
|
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
|
EP1560816A1
(en)
|
2002-07-05 |
2005-08-10 |
F. Hoffmann-La Roche Ag |
Quinazoline derivatives
|
|
EP1539722A1
(en)
|
2002-08-07 |
2005-06-15 |
F. Hoffmann-La Roche Ag |
Thiazole derivatives
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
EP1601357A4
(en)
*
|
2003-03-10 |
2007-10-03 |
Schering Corp |
HETEROCYCLIC KINASE INHIBITORS: METHOD OF USE AND SYNTHESIS
|
|
WO2005028438A1
(ja)
|
2003-09-22 |
2005-03-31 |
Banyu Pharmaceutical Co., Ltd. |
新規ピペリジン誘導体
|
|
EP1687002A4
(en)
|
2003-11-10 |
2008-07-23 |
Synta Pharmaceuticals Corp |
CONDENSED HETEROCYCLIC COMPOUNDS
|
|
EP1734963A4
(en)
|
2004-04-02 |
2008-06-18 |
Merck & Co Inc |
METHOD FOR TREATING PEOPLE WITH METABOLIC AND ANTHROPOMETRIC DISORDER
|
|
US20060183763A1
(en)
*
|
2004-12-31 |
2006-08-17 |
Pfizer Inc |
Novel pyrrolidyl derivatives of heteroaromatic compounds
|
|
NZ562766A
(en)
|
2005-05-30 |
2011-03-31 |
Banyu Pharma Co Ltd |
Piperidine derivatives as histamine-H3 receptor antagonists
|
|
EP1916239A4
(en)
|
2005-08-10 |
2009-10-21 |
Banyu Pharma Co Ltd |
PYRIDOLVERBINDUNG
|
|
AU2006282260A1
(en)
|
2005-08-24 |
2007-03-01 |
Msd K.K. |
Phenylpyridone derivative
|
|
US20090264426A1
(en)
|
2005-09-07 |
2009-10-22 |
Shunji Sakuraba |
Bicyclic aromatic substituted pyridone derivative
|
|
EP1944301A4
(en)
|
2005-10-27 |
2012-01-04 |
Msd Kk |
NEW BENZOXATHIIN DERIVATIVES
|
|
CA2629018C
(en)
|
2005-11-10 |
2013-12-31 |
Banyu Pharmaceutical Co., Ltd. |
Aza-substituted spiro derivative
|
|
WO2008020302A2
(en)
*
|
2006-08-17 |
2008-02-21 |
Pfizer Products Inc. |
Heteroaromatic quinoline-based compounds as phosphodiesterase (pde) inhibitors
|
|
WO2008038692A1
(en)
|
2006-09-28 |
2008-04-03 |
Banyu Pharmaceutical Co., Ltd. |
Diaryl ketimine derivative
|
|
US8106086B2
(en)
|
2007-04-02 |
2012-01-31 |
Msd K.K. |
Indoledione derivative
|
|
WO2008141077A1
(en)
*
|
2007-05-10 |
2008-11-20 |
Janssen Pharmaceutica N.V. |
Process for the preparation of tetrahydroquinolinyl, benzoxazine and benzothiazine derivatives
|
|
BRPI0811745B1
(pt)
*
|
2007-05-17 |
2019-06-04 |
Helperby Therapeutics Limited |
Compostos de 4-(pirrolidin-1-il)quinolina, uso e processo para a preparação dos mesmos, formulação farmacêutica --
|
|
CN101679853B
(zh)
*
|
2007-06-01 |
2013-10-30 |
E.I.内穆尔杜邦公司 |
用于绿色发光应用的*
|
|
MX354786B
(es)
|
2007-06-04 |
2018-03-21 |
Synergy Pharmaceuticals Inc |
Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
JP5269086B2
(ja)
|
2007-11-15 |
2013-08-21 |
ギリアード サイエンシス インコーポレーテッド |
ヒト免疫不全ウイルスの複製阻害薬
|
|
NZ585226A
(en)
|
2007-11-16 |
2012-08-31 |
Gilead Sciences Inc |
Inhibitors of human immunodeficiency virus replication
|
|
EP2264026A4
(en)
|
2008-03-06 |
2012-03-28 |
Msd Kk |
ALKYLAMINOPYRIDINDERIVATE
|
|
JPWO2009119726A1
(ja)
|
2008-03-28 |
2011-07-28 |
Ｍｓｄ株式会社 |
メラニン凝集ホルモン受容体拮抗作用を有するジアリールメチルアミド誘導体
|
|
CA2726917C
(en)
|
2008-06-04 |
2018-06-26 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
US20110071129A1
(en)
|
2008-06-19 |
2011-03-24 |
Makoto Ando |
Spirodiamine-diaryl ketoxime derivative
|
|
EP2321341B1
(en)
|
2008-07-16 |
2017-02-22 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
|
WO2010013595A1
(ja)
|
2008-07-30 |
2010-02-04 |
萬有製薬株式会社 |
５員－５員又は５員－６員縮環シクロアルキルアミン誘導体
|
|
US8410284B2
(en)
|
2008-10-22 |
2013-04-02 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
CA2741672A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
AU2011218830B2
(en)
|
2010-02-25 |
2014-07-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
CA2826649C
(en)
|
2011-02-25 |
2016-07-26 |
Merck Sharp & Dohme Corp. |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
|
RU2015106909A
(ru)
|
2012-08-02 |
2016-09-27 |
Мерк Шарп И Доум Корп. |
Антидиабетические трициклические соединения
|
|
BR112015019836A2
(pt)
|
2013-02-22 |
2017-07-18 |
Merck Sharp & Dohme |
composto, composição farmacêutica, e, uso de um composto
|
|
EP2970119B1
(en)
|
2013-03-14 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
|
WO2014151200A2
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
|
JP2016514671A
(ja)
|
2013-03-15 |
2016-05-23 |
シナジー ファーマシューティカルズ インコーポレイテッド |
グアニル酸シクラーゼのアゴニストおよびその使用
|
|
CN105764916B
(zh)
|
2013-06-05 |
2021-05-18 |
博士医疗爱尔兰有限公司 |
鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
|
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
US11072602B2
(en)
|
2016-12-06 |
2021-07-27 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
|
WO2018118670A1
(en)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
|
CN111793060B
(zh)
|
2017-07-14 |
2023-06-06 |
先天肿瘤免疫公司 |
Nlrp3调节剂
|