JP2004502736A - 吸入のためのマクロライド処方物および気管支内感染の処置の方法 - Google Patents

吸入のためのマクロライド処方物および気管支内感染の処置の方法 Download PDF

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Publication number
JP2004502736A
JP2004502736A JP2002508452A JP2002508452A JP2004502736A JP 2004502736 A JP2004502736 A JP 2004502736A JP 2002508452 A JP2002508452 A JP 2002508452A JP 2002508452 A JP2002508452 A JP 2002508452A JP 2004502736 A JP2004502736 A JP 2004502736A
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JP
Japan
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formulation
macrolide antibiotic
aerosol
nebulizer
erythromycylamine
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JP2002508452A
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English (en)
Japanese (ja)
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JP2004502736A5 (xx
Inventor
ベーカー，　ウィリアム　アール．
チャロナー，　ピーター　ビー．
シャワー，　リビ　エム．
フー，　ケイ　ケー．
リクマン，　デイビッド　エム．
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カイロン　コーポレイション
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Publication of JP2004502736A publication Critical patent/JP2004502736A/ja
Publication of JP2004502736A5 publication Critical patent/JP2004502736A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2002508452A 2000-07-10 2001-07-10 吸入のためのマクロライド処方物および気管支内感染の処置の方法 Pending JP2004502736A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21703200P 2000-07-10 2000-07-10
PCT/US2001/041328 WO2002003998A2 (en) 2000-07-10 2001-07-10 Macrolide formulations for inhalation and methods of treatment of endobronchial infections

Publications (2)

Publication Number Publication Date
JP2004502736A true JP2004502736A (ja) 2004-01-29
JP2004502736A5 JP2004502736A5 (xx) 2008-08-28

Family

ID=22809403

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002508452A Pending JP2004502736A (ja) 2000-07-10 2001-07-10 吸入のためのマクロライド処方物および気管支内感染の処置の方法

Country Status (11)

Country Link
EP (1) EP1309332A2 (xx)
JP (1) JP2004502736A (xx)
KR (1) KR20030020924A (xx)
CN (1) CN1202831C (xx)
AU (2) AU8349101A (xx)
BR (1) BR0112330A (xx)
CA (1) CA2415498A1 (xx)
IL (1) IL153875A0 (xx)
MX (1) MXPA03000321A (xx)
NZ (1) NZ523693A (xx)
WO (1) WO2002003998A2 (xx)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ， インク． 細胞内感染を予防及び治療するための吸入システム
JP2007536524A (ja) * 2004-05-06 2007-12-13 カイロン コーポレイション マクロライドの検出のための方法およびシステム
JP2013522229A (ja) * 2010-03-10 2013-06-13 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド抗生物質の非経口製剤
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
US9072759B2 (en) 2008-10-24 2015-07-07 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9200026B2 (en) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Antibacterial agents
JP2016513688A (ja) * 2013-03-14 2016-05-16 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
US9453042B2 (en) 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US10188674B2 (en) 2012-03-27 2019-01-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003205499A1 (en) * 2003-02-28 2004-09-17 Anbics Patents-Licences Ag Method for treatment and prevention of acute and chronic pseudomonas aeruginosa airway infections with inhalable macrolides
CN1805725A (zh) * 2003-06-10 2006-07-19 安斯泰来制药有限公司 密封容器中密封了含有大环内酯系化合物的气溶胶组合物的气溶胶制剂
DE602005025754D1 (de) 2004-05-17 2011-02-17 Corus Pharma Inc Kombination aus fosfomycin/aminoglycosid in aerosolform zur behandlung bakterieller atemwegsinfektionen
US20100093650A1 (en) 2006-10-11 2010-04-15 Laboratories Smb S.A. Pharmaceutical Anit-Infective Composition for Inhalation
EP2030644A1 (en) * 2007-08-31 2009-03-04 PARI Pharma GmbH Aerosols for sinunasal drug delivery
EP2098219A1 (en) 2008-03-05 2009-09-09 PARI Pharma GmbH Macrolide compositions having improved taste and stability
FI20205368A1 (en) * 2020-04-07 2021-10-08 Aalto Univ Foundation Sr FORMULATION
CN114796116A (zh) * 2022-05-17 2022-07-29 中山大学附属第六医院 一种阿奇霉素吸入剂及其制备方法

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JPS60209517A (ja) * 1984-04-03 1985-10-22 Unitika Ltd エアゾ−ル組成物
JPS63211223A (ja) * 1986-11-06 1988-09-02 リサーチ　デベロップメント　ファウンデイション 医療用のリポソームおよび薬物含有リポソームのエアゾールの小粒子
JPH01283225A (ja) * 1988-05-10 1989-11-14 Toyo Jozo Co Ltd 牛呼吸器感染症治療用エアゾール製剤およびそれを用いる治療方法
WO1999016419A1 (en) * 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Perforated microparticles and methods of use
WO2000012116A1 (en) * 1998-08-28 2000-03-09 Eli Lilly And Company Method for administering insulinotropic peptides
WO2000025746A2 (en) * 1998-11-03 2000-05-11 Chiesi Farmaceutici S.P.A. A process for the preparation of suspensions of drug particles for inhalation delivery
WO2000035461A1 (en) * 1998-12-17 2000-06-22 Pathogenesis Corporation Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic

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WO1990006775A1 (en) * 1988-12-14 1990-06-28 Liposome Technology, Inc. A novel nonphospholipid liposome composition for sustained release of drugs
AU1299095A (en) * 1993-12-02 1995-06-19 Cytrx Corporation Antiinfective compositions and methods of use
US5610198A (en) * 1994-03-18 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services Anti-mycobacterial compositions and their use for the treatment of tuberculosis and related diseases
US5693337A (en) * 1994-07-13 1997-12-02 Wakamoto Pharmaceutical Co., Ltd. Stable lipid emulsion
DE19518917A1 (de) * 1995-05-23 1996-11-28 Boehringer Ingelheim Vetmed Stabile, konzentrierte lokalverträgliche Erythromycylamin-Lösungen
WO2000015207A2 (en) * 1998-09-15 2000-03-23 Naeja Pharmaceutical Inc. Combination for the treatment of inflammation using elastine inhibitor(s) and antibacterial agent(s)
US6316433B1 (en) * 1998-12-18 2001-11-13 Kaneka Corporation Method for treatment of bacterial infections with once or twice-weekly administered rifalazil
US6156294A (en) * 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60209517A (ja) * 1984-04-03 1985-10-22 Unitika Ltd エアゾ−ル組成物
JPS63211223A (ja) * 1986-11-06 1988-09-02 リサーチ　デベロップメント　ファウンデイション 医療用のリポソームおよび薬物含有リポソームのエアゾールの小粒子
JPH01283225A (ja) * 1988-05-10 1989-11-14 Toyo Jozo Co Ltd 牛呼吸器感染症治療用エアゾール製剤およびそれを用いる治療方法
WO1999016419A1 (en) * 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Perforated microparticles and methods of use
WO2000012116A1 (en) * 1998-08-28 2000-03-09 Eli Lilly And Company Method for administering insulinotropic peptides
JP2002523466A (ja) * 1998-08-28 2002-07-30 イーライ・リリー・アンド・カンパニー インスリン向性ペプチドの投与方法
WO2000025746A2 (en) * 1998-11-03 2000-05-11 Chiesi Farmaceutici S.P.A. A process for the preparation of suspensions of drug particles for inhalation delivery
JP2002528484A (ja) * 1998-11-03 2002-09-03 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 吸入搬送用薬剤粒子の懸濁液を製造する方法
WO2000035461A1 (en) * 1998-12-17 2000-06-22 Pathogenesis Corporation Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ， インク． 細胞内感染を予防及び治療するための吸入システム
US9200026B2 (en) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Antibacterial agents
JP2007536524A (ja) * 2004-05-06 2007-12-13 カイロン コーポレイション マクロライドの検出のための方法およびシステム
US10131684B2 (en) 2007-10-25 2018-11-20 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US9453042B2 (en) 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US9072759B2 (en) 2008-10-24 2015-07-07 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9439918B2 (en) 2008-10-24 2016-09-13 Cempra Pharmaceuticals, Inc. Methods for treating gastrointestinal diseases
US9669046B2 (en) 2008-10-24 2017-06-06 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9901592B2 (en) 2008-10-24 2018-02-27 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP2013522229A (ja) * 2010-03-10 2013-06-13 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド抗生物質の非経口製剤
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
US10188674B2 (en) 2012-03-27 2019-01-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
JP2016513688A (ja) * 2013-03-14 2016-05-16 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
US9861616B2 (en) 2013-03-14 2018-01-09 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
JP2019048826A (ja) * 2013-03-14 2019-03-28 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Also Published As

Publication number Publication date
WO2002003998A2 (en) 2002-01-17
CN1471401A (zh) 2004-01-28
EP1309332A2 (en) 2003-05-14
CN1202831C (zh) 2005-05-25
AU8349101A (en) 2002-01-21
NZ523693A (en) 2004-08-27
WO2002003998A3 (en) 2002-06-13
AU2001283491B2 (en) 2007-02-15
IL153875A0 (en) 2003-07-31
MXPA03000321A (es) 2003-06-06
KR20030020924A (ko) 2003-03-10
BR0112330A (pt) 2003-10-07
CA2415498A1 (en) 2002-01-17

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