BR0112330A - Formulações de macrolìdeos para inalação e seus usos para o tratamento de infecções endobrÈnquicas - Google Patents
Formulações de macrolìdeos para inalação e seus usos para o tratamento de infecções endobrÈnquicasInfo
- Publication number
- BR0112330A BR0112330A BR0112330-0A BR0112330A BR0112330A BR 0112330 A BR0112330 A BR 0112330A BR 0112330 A BR0112330 A BR 0112330A BR 0112330 A BR0112330 A BR 0112330A
- Authority
- BR
- Brazil
- Prior art keywords
- formulation
- formulations
- inhalation
- treatment
- infections
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
"FORMULAçõES DE MACROLìDEOS PARA INALAçãO E SEUS USOS PARA O TRATAMENTO DE INFECçõES ENDOBRÈNQUICAS". São descritas formulações de macrolídeos, tal como uma formulação de eritromicilamina, para liberação por aerossol. As formulações de eritromicilamina concentradas contêm uma quantidade de eritromicilamina eficaz para tratar infecções causadas por bactérias suscetíveis. Dispositivos de dose unitária tendo um recipiente contendo uma formulação do antibiótico macrolídeo em um transportador fisiologicamente aceitável também são descritos. Também são descritos métodos para tratamento de infecções pulmonares por uma formulação (solução líquida, suspensão ou pó seco) liberada como um aerossol tendo diâmetro aerodinâmico mediano de massa predominantemente entre 1 a 5 gm de tamanho.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21703200P | 2000-07-10 | 2000-07-10 | |
PCT/US2001/041328 WO2002003998A2 (en) | 2000-07-10 | 2001-07-10 | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0112330A true BR0112330A (pt) | 2003-10-07 |
Family
ID=22809403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0112330-0A BR0112330A (pt) | 2000-07-10 | 2001-07-10 | Formulações de macrolìdeos para inalação e seus usos para o tratamento de infecções endobrÈnquicas |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1309332A2 (pt) |
JP (1) | JP2004502736A (pt) |
KR (1) | KR20030020924A (pt) |
CN (1) | CN1202831C (pt) |
AU (2) | AU8349101A (pt) |
BR (1) | BR0112330A (pt) |
CA (1) | CA2415498A1 (pt) |
IL (1) | IL153875A0 (pt) |
MX (1) | MXPA03000321A (pt) |
NZ (1) | NZ523693A (pt) |
WO (1) | WO2002003998A2 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003075889A1 (en) * | 2002-03-05 | 2003-09-18 | Transave, Inc. | An inhalation system for prevention and treatment of intracellular infections |
WO2004075874A1 (en) * | 2003-02-28 | 2004-09-10 | Anbics Patents-Licences Ag | Method for treatment and prevention of acute and chronic pseudomonas aeruginosa airway infections with inhalable macrolides |
EP2772254A3 (en) | 2003-03-10 | 2015-03-11 | Optimer Pharmaceuticals, Inc. | Novel Antibacterial Agents |
KR20060067922A (ko) * | 2003-06-10 | 2006-06-20 | 아스텔라스세이야쿠 가부시키가이샤 | 마크로라이드계 화합물을 함유하는 에어로졸 조성물이봉입용기에 봉입된 에어로졸 제제 |
US20050266578A1 (en) * | 2004-05-06 | 2005-12-01 | Gruenke Larry D | Methods and systems for detection of macrolides |
PT2316419E (pt) | 2004-05-17 | 2012-10-22 | Gilead Sciences Inc | Combinação de fosfomicina/aminoglicósido em aerossol para o tratamento de infeções respiratórias bacterianas |
WO2008043825A2 (en) * | 2006-10-11 | 2008-04-17 | Laboratoires Smb S.A. | Pharmaceutical anti-infective composition for inhalation. |
EP2030644A1 (en) * | 2007-08-31 | 2009-03-04 | PARI Pharma GmbH | Aerosols for sinunasal drug delivery |
JP5698979B2 (ja) | 2007-10-25 | 2015-04-08 | センプラ ファーマシューティカルズ,インコーポレイテッド | マクロライド系抗菌剤の調製プロセス |
EP2098219A1 (en) * | 2008-03-05 | 2009-09-09 | PARI Pharma GmbH | Macrolide compositions having improved taste and stability |
CN105616437A (zh) | 2008-10-24 | 2016-06-01 | 森普拉制药公司 | 使用含三唑的大环内酯的生物防御 |
US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
JP5890785B2 (ja) * | 2010-03-10 | 2016-03-22 | センプラ ファーマシューティカルズ,インコーポレイテッド | マクロライド抗生物質の非経口製剤 |
DK2571506T3 (en) | 2010-05-20 | 2017-08-28 | Cempra Pharmaceuticals Inc | PROCEDURES FOR THE MANUFACTURE OF MACROLIDES AND KETOLIDES AND INTERMEDIATES |
US9815863B2 (en) | 2010-09-10 | 2017-11-14 | Cempra Pharmaceuticals, Inc. | Hydrogen bond forming fluoro ketolides for treating diseases |
RU2658050C2 (ru) | 2012-03-27 | 2018-06-19 | Семпра Фармасьютикалз, Инк. | Парентеральные составы для введения макролидных антибиотиков |
JP6426696B2 (ja) * | 2013-03-14 | 2018-11-21 | センプラ ファーマシューティカルズ,インコーポレイテッド | 呼吸器疾患の治療のための方法および製剤 |
CA2907085A1 (en) | 2013-03-15 | 2014-09-18 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
FI20205368A1 (en) * | 2020-04-07 | 2021-10-08 | Aalto Univ Foundation Sr | FORMULATION |
CN114796116A (zh) * | 2022-05-17 | 2022-07-29 | 中山大学附属第六医院 | 一种阿奇霉素吸入剂及其制备方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60209517A (ja) * | 1984-04-03 | 1985-10-22 | Unitika Ltd | エアゾ−ル組成物 |
IE63869B1 (en) * | 1986-11-06 | 1995-06-14 | Res Dev Foundation | Aerosols containing liposomes and method for their preparation |
JPH01283225A (ja) * | 1988-05-10 | 1989-11-14 | Toyo Jozo Co Ltd | 牛呼吸器感染症治療用エアゾール製剤およびそれを用いる治療方法 |
WO1990006775A1 (en) * | 1988-12-14 | 1990-06-28 | Liposome Technology, Inc. | A novel nonphospholipid liposome composition for sustained release of drugs |
WO1995015182A1 (en) * | 1993-12-02 | 1995-06-08 | Emory University | Antiinfective compositions and methods of use |
US5610198A (en) * | 1994-03-18 | 1997-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Anti-mycobacterial compositions and their use for the treatment of tuberculosis and related diseases |
CA2153553A1 (en) * | 1994-07-13 | 1996-01-14 | Hidekazu Suzuki | Stable lipid emulsion |
DE19518917A1 (de) * | 1995-05-23 | 1996-11-28 | Boehringer Ingelheim Vetmed | Stabile, konzentrierte lokalverträgliche Erythromycylamin-Lösungen |
DE69814428T2 (de) * | 1997-09-29 | 2004-05-13 | Nektar Therapeutics, San Carlos | In verneblern verwendbare, stabilisierte zubereitungen |
AR022368A1 (es) * | 1998-08-28 | 2002-09-04 | Lilly Co Eli | Procedimiento para administrar peptidos insulinotropicos |
AU5528299A (en) * | 1998-09-15 | 2000-04-03 | Naeja Pharmaceutical Inc. | Combined therapy for treatment of inflammation using elastase inhibitor(s) and antibacterial agent(s) |
IT1303692B1 (it) * | 1998-11-03 | 2001-02-23 | Chiesi Farma Spa | Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione. |
CZ20012147A3 (cs) * | 1998-12-17 | 2003-01-15 | Chiron Corporation | Farmaceutický prostředek ve formě suchého práąku nebo rozpráąeného aerosolového prostředku pro léčení chronické bronchitidy |
US6316433B1 (en) * | 1998-12-18 | 2001-11-13 | Kaneka Corporation | Method for treatment of bacterial infections with once or twice-weekly administered rifalazil |
US6156294A (en) * | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
-
2001
- 2001-07-01 NZ NZ523693A patent/NZ523693A/en unknown
- 2001-07-10 CA CA002415498A patent/CA2415498A1/en not_active Abandoned
- 2001-07-10 EP EP01962298A patent/EP1309332A2/en not_active Withdrawn
- 2001-07-10 AU AU8349101A patent/AU8349101A/xx active Pending
- 2001-07-10 CN CNB018141218A patent/CN1202831C/zh not_active Expired - Fee Related
- 2001-07-10 IL IL15387501A patent/IL153875A0/xx unknown
- 2001-07-10 JP JP2002508452A patent/JP2004502736A/ja active Pending
- 2001-07-10 AU AU2001283491A patent/AU2001283491B2/en not_active Ceased
- 2001-07-10 BR BR0112330-0A patent/BR0112330A/pt not_active IP Right Cessation
- 2001-07-10 WO PCT/US2001/041328 patent/WO2002003998A2/en active IP Right Grant
- 2001-07-10 KR KR10-2003-7000412A patent/KR20030020924A/ko not_active Application Discontinuation
- 2001-07-10 MX MXPA03000321A patent/MXPA03000321A/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR20030020924A (ko) | 2003-03-10 |
CN1202831C (zh) | 2005-05-25 |
EP1309332A2 (en) | 2003-05-14 |
CA2415498A1 (en) | 2002-01-17 |
AU8349101A (en) | 2002-01-21 |
IL153875A0 (en) | 2003-07-31 |
AU2001283491B2 (en) | 2007-02-15 |
WO2002003998A3 (en) | 2002-06-13 |
MXPA03000321A (es) | 2003-06-06 |
JP2004502736A (ja) | 2004-01-29 |
WO2002003998A2 (en) | 2002-01-17 |
NZ523693A (en) | 2004-08-27 |
CN1471401A (zh) | 2004-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) Free format text: ALTERADO DE: CHIRON CORPORATION |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: CONFORME ARTIGO 10O DA RESOLUCAO 124/06, CABE SER ARQUIVADO REFERENTE AO NAO RECOLHIMENTO DA 9A E 10A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |