MXPA03000321A - Formulaciones de macrolido para inhalacion y metodos de tratamiento de infecciones endobronquiales. - Google Patents

Formulaciones de macrolido para inhalacion y metodos de tratamiento de infecciones endobronquiales.

Info

Publication number
MXPA03000321A
MXPA03000321A MXPA03000321A MXPA03000321A MXPA03000321A MX PA03000321 A MXPA03000321 A MX PA03000321A MX PA03000321 A MXPA03000321 A MX PA03000321A MX PA03000321 A MXPA03000321 A MX PA03000321A MX PA03000321 A MXPA03000321 A MX PA03000321A
Authority
MX
Mexico
Prior art keywords
erythromycylamine
formulation
treatment
methods
macrolide
Prior art date
Application number
MXPA03000321A
Other languages
English (en)
Inventor
William R Baker
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of MXPA03000321A publication Critical patent/MXPA03000321A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Se proporcionan formulaciones de macrolido tales como una formulacion de eritromicilamina para suministro por formacion de aerosol. Las formulaciones concentradas de eritromicilamina contienen una cantidad de eritromicilamina eficaz para tratar infecciones causadas por bacterias susceptibles. También se proporcionan dispositivos de dosis unitaria que tienen un envase que contiene una formulacion del macrolido antibiotico en un vehículo fisiologicamente aceptable. También se describen métodos para el tratamiento de infecciones pulmonares por una formulacion (solucion líquida, suspension o polvo seco) que se suministra como un aerosol que tiene una mediana de masa de diámetro aerodinámico predominantemente entre 1 y 5 °m.
MXPA03000321A 2000-07-10 2001-07-10 Formulaciones de macrolido para inhalacion y metodos de tratamiento de infecciones endobronquiales. MXPA03000321A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21703200P 2000-07-10 2000-07-10
PCT/US2001/041328 WO2002003998A2 (en) 2000-07-10 2001-07-10 Macrolide formulations for inhalation and methods of treatment of endobronchial infections

Publications (1)

Publication Number Publication Date
MXPA03000321A true MXPA03000321A (es) 2003-06-06

Family

ID=22809403

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03000321A MXPA03000321A (es) 2000-07-10 2001-07-10 Formulaciones de macrolido para inhalacion y metodos de tratamiento de infecciones endobronquiales.

Country Status (11)

Country Link
EP (1) EP1309332A2 (es)
JP (1) JP2004502736A (es)
KR (1) KR20030020924A (es)
CN (1) CN1202831C (es)
AU (2) AU8349101A (es)
BR (1) BR0112330A (es)
CA (1) CA2415498A1 (es)
IL (1) IL153875A0 (es)
MX (1) MXPA03000321A (es)
NZ (1) NZ523693A (es)
WO (1) WO2002003998A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003225689B2 (en) * 2002-03-05 2009-03-26 Transave, Inc. Methods for entrapment of bioactive agent in a liposome or lipid complex
AU2003205499A1 (en) * 2003-02-28 2004-09-17 Anbics Patents-Licences Ag Method for treatment and prevention of acute and chronic pseudomonas aeruginosa airway infections with inhalable macrolides
EP1638549A4 (en) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc NEW ANTIBACTERIAL AGENTS
RU2005141549A (ru) * 2003-06-10 2006-06-10 Астеллас Фарма Инк. (Jp) Аэрозольное средство, содержащее емкость, в которой заключена аэрозольная композиция, включающая соединение макролида
US20050266578A1 (en) * 2004-05-06 2005-12-01 Gruenke Larry D Methods and systems for detection of macrolides
DK2266534T3 (da) 2004-05-17 2013-01-14 Gilead Sciences Inc Aerosoliseret fosfomycin/tobramycin-kombination til behandling af cystisk fibrose
WO2008043825A2 (en) * 2006-10-11 2008-04-17 Laboratoires Smb S.A. Pharmaceutical anti-infective composition for inhalation.
EP2030644A1 (en) * 2007-08-31 2009-03-04 PARI Pharma GmbH Aerosols for sinunasal drug delivery
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
EP2098219A1 (en) 2008-03-05 2009-09-09 PARI Pharma GmbH Macrolide compositions having improved taste and stability
US8796232B2 (en) 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5890785B2 (ja) * 2010-03-10 2016-03-22 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド抗生物質の非経口製剤
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
WO2014152326A1 (en) * 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
FI20205368A1 (en) * 2020-04-07 2021-10-08 Aalto Univ Foundation Sr FORMULATION
CN114796116A (zh) * 2022-05-17 2022-07-29 中山大学附属第六医院 一种阿奇霉素吸入剂及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60209517A (ja) * 1984-04-03 1985-10-22 Unitika Ltd エアゾ−ル組成物
IE63869B1 (en) * 1986-11-06 1995-06-14 Res Dev Foundation Aerosols containing liposomes and method for their preparation
JPH01283225A (ja) * 1988-05-10 1989-11-14 Toyo Jozo Co Ltd 牛呼吸器感染症治療用エアゾール製剤およびそれを用いる治療方法
WO1990006775A1 (en) * 1988-12-14 1990-06-28 Liposome Technology, Inc. A novel nonphospholipid liposome composition for sustained release of drugs
AU1299095A (en) * 1993-12-02 1995-06-19 Cytrx Corporation Antiinfective compositions and methods of use
US5610198A (en) * 1994-03-18 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services Anti-mycobacterial compositions and their use for the treatment of tuberculosis and related diseases
US5693337A (en) * 1994-07-13 1997-12-02 Wakamoto Pharmaceutical Co., Ltd. Stable lipid emulsion
DE19518917A1 (de) * 1995-05-23 1996-11-28 Boehringer Ingelheim Vetmed Stabile, konzentrierte lokalverträgliche Erythromycylamin-Lösungen
ATE239447T1 (de) * 1997-09-29 2003-05-15 Inhale Therapeutic Syst In verneblern verwendbare, stabilisierte zubereitungen
CN1314818A (zh) * 1998-08-28 2001-09-26 伊莱利利公司 服用促胰岛素肽的方法
AU5528299A (en) * 1998-09-15 2000-04-03 Naeja Pharmaceutical Inc. Combined therapy for treatment of inflammation using elastase inhibitor(s) and antibacterial agent(s)
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
HUP0105226A3 (en) * 1998-12-17 2003-03-28 Pathogenesis Corp Seattle Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic
US6316433B1 (en) * 1998-12-18 2001-11-13 Kaneka Corporation Method for treatment of bacterial infections with once or twice-weekly administered rifalazil
US6156294A (en) * 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media

Also Published As

Publication number Publication date
WO2002003998A2 (en) 2002-01-17
AU2001283491B2 (en) 2007-02-15
CA2415498A1 (en) 2002-01-17
JP2004502736A (ja) 2004-01-29
BR0112330A (pt) 2003-10-07
NZ523693A (en) 2004-08-27
WO2002003998A3 (en) 2002-06-13
AU8349101A (en) 2002-01-21
CN1202831C (zh) 2005-05-25
EP1309332A2 (en) 2003-05-14
CN1471401A (zh) 2004-01-28
KR20030020924A (ko) 2003-03-10
IL153875A0 (en) 2003-07-31

Similar Documents

Publication Publication Date Title
MXPA03000321A (es) Formulaciones de macrolido para inhalacion y metodos de tratamiento de infecciones endobronquiales.
GR3031770T3 (en) Novel and improved aminoglycoside formulation for aerosolization
TW200608983A (en) Aerosolized fosfomycin/aminoglycoside combination for the treatment of bacterial respiratory infections
DE60210402D1 (de) System zur Abgabe einer Tobramycin-Formulierung
MY121789A (en) Closure-cap and container as a two-chamber cartridge for nebulisers for producing aerosols and active substance formulations, suitable for storage
LV12586A (en) Aerosolized active agent delivery
GB9410222D0 (en) Medicaments
IL149085A0 (en) A dry powder composition containing a di or tripeptide
IL130512A0 (en) Medicament delivery and packaging
AP1646A (en) Flow resistance modulated aerosolized active agent delivery.
WO2001049274A3 (en) Methods for pulmonary delivery of interleukin-2
CY2008A (en) Pharmaceutical aerosol formulation
ES2178943A1 (es) Uso de compuestos organicos en el tratamiento de enfermedad pulmonar obstructiva cronica.
CA2369722A1 (en) Powder inhaler for combined medicament
CA2277913A1 (en) New formulation for inhalation having a poured bulk density of 0.28 to 0.38 g/ml, a process for preparing the formulation and the use thereof
CA2343123A1 (en) Active substance concentrate with formoterol, suitable for storage
CA2369726A1 (en) Powder inhaler for combined medicament
PL356817A1 (en) Gamma-ifn liquid-droplet aerosol and method
PL1684719T3 (pl) Kompozycje alfa 1-antytrypsyny i sposoby leczenia z zastosowaniem takich kompozycji
WO2002024261A3 (en) Shock wave aerosolization apparatus and method
WO2005037256A3 (de) Flüssige zubereitung enthaltend tobramycin
CN109999031A (zh) 一种含有苯唑西林的医药组合物
UA88863C2 (ru) Система для ингаляции сухим порошком, лиофилизированный состав, ингалятор сухого порошка (варианты), способ изготовления сухого порошкообразного препарата для транспульмонарного применения, способ транспульмонарного применения, применение лиофилизированного состава для транспульмонарного применения при помощи ингаляции (варианты)
NO20034873L (no) Aerosolformuleringer inneholdende estere av 3,17-dihydroksy degree stratrienderivater for pulmonar avlevering

Legal Events

Date Code Title Description
FG Grant or registration
HC Change of company name or juridical status