BRPI0408854A - veìculo de disfarce de sabor para partìculas de oxazolidinona revestidas - Google Patents
veìculo de disfarce de sabor para partìculas de oxazolidinona revestidasInfo
- Publication number
- BRPI0408854A BRPI0408854A BRPI0408854-9A BRPI0408854A BRPI0408854A BR PI0408854 A BRPI0408854 A BR PI0408854A BR PI0408854 A BRPI0408854 A BR PI0408854A BR PI0408854 A BRPI0408854 A BR PI0408854A
- Authority
- BR
- Brazil
- Prior art keywords
- particles
- oxazolidinone
- coated
- vehicle
- flavor masking
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
"VEìCULO DE DISFARCE DE SABOR PARA PARTìCULAS DE OXAZOLIDINONA REVESTIDAS". A presente invenção é direcionada para as formulações secas de partículas de oxazolidinona revestidas, tais como as partículas de linezolida revestidas, que, quando suspensas em uma solução aquosa, disfarçam o sabor da oxazolidinona no veículo de suspensão resultante. Especificamente, uma mistura de açúcares na formulação, compreendendo sorbitol e sacarose, inibe o transporte em massa da oxazolidinona a partir das partículas para o veículo de suspensão. As formulações secas das partículas de oxazolidinona revestidas, as suspensões das mesmas e os métodos de utilização destas para tratar ou prevenir infecções por bactérias gram-positivas são todos divulgados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45938203P | 2003-03-31 | 2003-03-31 | |
PCT/IB2004/000921 WO2004087108A1 (en) | 2003-03-31 | 2004-03-19 | Taste-masking vehicle for coated oxazolidinone particles |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0408854A true BRPI0408854A (pt) | 2006-04-04 |
Family
ID=33131883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0408854-9A BRPI0408854A (pt) | 2003-03-31 | 2004-03-19 | veìculo de disfarce de sabor para partìculas de oxazolidinona revestidas |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040191326A1 (pt) |
EP (1) | EP1610764A1 (pt) |
JP (1) | JP2006522089A (pt) |
BR (1) | BRPI0408854A (pt) |
CA (1) | CA2519869A1 (pt) |
MX (1) | MXPA05010629A (pt) |
WO (1) | WO2004087108A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040170686A1 (en) * | 2003-01-31 | 2004-09-02 | Fredrickson Jennifer K. | Suspension vehicle for coated drug particles |
WO2010046933A2 (en) | 2008-10-22 | 2010-04-29 | Rubicon Research Private Limited | Pharmaceutical compositions of taste-masked linezolid |
US9987233B2 (en) | 2013-03-21 | 2018-06-05 | Eupraxia Pharmaceuticals USA LLC | Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith |
KR20170056573A (ko) * | 2014-09-19 | 2017-05-23 | 유프락시아 파마수티컬스 인코포레이티드 | 치료제의 고도로 국소화된 방출을 위한 주입가능한 미립자 |
TR201808237T4 (tr) | 2015-10-27 | 2018-07-23 | Eupraxia Pharmaceuticals Inc | Lokal anestetiklerin sürekli salım formülasyonları. |
CN105853351B (zh) * | 2016-03-31 | 2019-02-22 | 重庆华邦制药有限公司 | 利奈唑胺口服混悬液及其制备方法 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8103843L (sv) * | 1981-06-18 | 1982-12-19 | Astra Laekemedel Ab | Farmaceutisk mixtur |
US4994260A (en) * | 1982-05-28 | 1991-02-19 | Astra Lakemedel Aktiebolag | Pharmaceutical mixture |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
IT1183574B (it) * | 1985-05-08 | 1987-10-22 | Eurand Spa | Metodo per ottenere una sospensione estemporanea omogenea di microcapsule |
SE8605515D0 (sv) * | 1986-12-22 | 1986-12-22 | Astra Laekemedel Ab | A liquid dosage form for oral administration of a pharmaceutically active substance |
US4788220A (en) * | 1987-07-08 | 1988-11-29 | American Home Products Corporation (Del.) | Pediatric ibuprofen compositions |
US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
US5082669A (en) * | 1989-07-20 | 1992-01-21 | Dainippon Pharmaceutical Co., Ltd. | Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked |
US5231188A (en) * | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
IT1246350B (it) * | 1990-07-11 | 1994-11-17 | Eurand Int | Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili |
KR100257418B1 (ko) * | 1991-11-01 | 2000-05-15 | 로렌스 티. 마이젠헬더 | 치환된 아릴-및 헤테로아릴-페닐옥사졸리디논 |
US5272137A (en) * | 1992-02-14 | 1993-12-21 | Mcneil-Pfc, Inc. | Aqueous pharmaceutical suspension for pharmaceutical actives |
TW271400B (pt) * | 1992-07-30 | 1996-03-01 | Pfizer | |
CA2121435C (en) * | 1993-04-16 | 2002-01-22 | Sheila M. Ratnaraj | Aqueous pharmaceutical suspension and process for preparation thereof |
US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
WO1995014684A1 (en) * | 1993-11-22 | 1995-06-01 | The Upjohn Company | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
DE4425612A1 (de) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
WO1996003976A1 (en) * | 1994-08-01 | 1996-02-15 | Kv Pharmaceutical Corporation | Tastemasked liquid pharmaceutical delivery system |
GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
AUPN969796A0 (en) * | 1996-05-07 | 1996-05-30 | F.H. Faulding & Co. Limited | Taste masked liquid suspensions |
GB2318511A (en) * | 1996-10-23 | 1998-04-29 | Eurand Int | Process for the preparation of a pharmaceutical composition for rapid suspension in water |
KR20010015910A (ko) * | 1998-01-23 | 2001-02-26 | 로렌스 티. 마이젠헬더 | 옥사졸리디논 조합 라이브러리, 조성물 및 제조 방법 |
FR2795962B1 (fr) * | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
US6451345B1 (en) * | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
US6495154B1 (en) * | 2000-11-21 | 2002-12-17 | Vivus Inc. | On demand administration of clomipramine and salts thereof to treat premature ejaculation |
-
2004
- 2004-03-01 US US10/790,312 patent/US20040191326A1/en not_active Abandoned
- 2004-03-19 EP EP04721966A patent/EP1610764A1/en not_active Withdrawn
- 2004-03-19 CA CA002519869A patent/CA2519869A1/en not_active Abandoned
- 2004-03-19 JP JP2006506396A patent/JP2006522089A/ja not_active Withdrawn
- 2004-03-19 WO PCT/IB2004/000921 patent/WO2004087108A1/en active Application Filing
- 2004-03-19 MX MXPA05010629A patent/MXPA05010629A/es unknown
- 2004-03-19 BR BRPI0408854-9A patent/BRPI0408854A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
MXPA05010629A (es) | 2005-12-12 |
JP2006522089A (ja) | 2006-09-28 |
WO2004087108A1 (en) | 2004-10-14 |
US20040191326A1 (en) | 2004-09-30 |
EP1610764A1 (en) | 2006-01-04 |
CA2519869A1 (en) | 2004-10-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60327438D1 (de) | Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen | |
AR021074A1 (es) | COMPOSICIoN FARMACÉUTICA DE MOXIFLOXACINA, PROCEDIMIENTO PARA SU PRODUCCIoN, Y USO DE DICHA COMPOSICIoN PARA PREPARAR UN MEDICAMENTO ANTIBACTERIANO. | |
ID21526A (id) | 4-hidroksiquinolin-3-karboksamida dan hidrazida sebagai bahan anti-virus | |
CY1113283T1 (el) | Αερολυματοποιημενος συνδυασμος φωσφομυκινης/τομπραμυκινης για την αγωγη των βακτηριδιακων αναπνευστικων λοιμωξεων | |
ATE538774T1 (de) | Pharmazeutische formulierungen und verfahren zur behandlung von atemwegsinfektionen | |
WO2009154304A3 (en) | A pharmaceutical composition comprising rebamipide | |
MXPA05009015A (es) | Nuevos derivados de bencimidazol e imidazo-piridina y su utilizacion como medicamentos. | |
BR0013010A (pt) | Formulação de cloreto de sódio de moxifloxacina | |
NO20063047L (no) | Vandige ciclesonidsuspensjoner for forstoving | |
RU2010123174A (ru) | Профилактика и лечение вторичных инфекций после вирусной инфекции | |
PH12019502033A1 (en) | Pharmaceutical composition comprising selexipag | |
BR0112330A (pt) | Formulações de macrolìdeos para inalação e seus usos para o tratamento de infecções endobrÈnquicas | |
BRPI0408854A (pt) | veìculo de disfarce de sabor para partìculas de oxazolidinona revestidas | |
BR0306738A (pt) | Processo e aparelho para preparar partìculas cristalinas de uma substância, população de partìculas, e, composição farmacêutica | |
WO2005041919A3 (de) | Medikamentöse gezielte lokale lipolyse | |
BR0310046A (pt) | Atenuação de metapneumovìrus | |
NO20090067L (no) | Farmasoytiske kombinasjoner for behandling av respiratoriske sykdommer | |
ATE267816T1 (de) | Tan-1057 derivate | |
PT1223972E (pt) | Suspensao de uma proteina de epi-hne processo para a sua preparacao aerossol de po anidro derivado dela composicoes farmaceuticas contendo a referida suspensao ou aerossol e as suas utilizacoes | |
BRPI0514380A (pt) | amidas de ácido 5- e 6-amnoalquil indol-2-carboxìlico 3-substituìdo e análogos relacionados como inibidores de caseìna quinase i | |
EP1114826A3 (en) | Novel antibacterial and prokinetic macrolides | |
TW200738599A (en) | New pleuromutilin derivative and its use | |
MX2019002386A (es) | Uso de oligosacaridos de leche humana en el engorde de terneros. | |
BRPI0411524A (pt) | formulação farmacêutica de amoxicilina e clavulanato, uso de carboximetilcelulose de sódio, e, método de tratar infecção bacteriana em pacientes pediátricos | |
HUP0202888A2 (hu) | Xenogén oligo- és/vagy poliribonukleotidokat tartalmazó gyógyszerkészítmény |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011. |