JP2003524421A5 - - Google Patents

Download PDF

Info

Publication number
JP2003524421A5
JP2003524421A5 JP2001561344A JP2001561344A JP2003524421A5 JP 2003524421 A5 JP2003524421 A5 JP 2003524421A5 JP 2001561344 A JP2001561344 A JP 2001561344A JP 2001561344 A JP2001561344 A JP 2001561344A JP 2003524421 A5 JP2003524421 A5 JP 2003524421A5
Authority
JP
Japan
Prior art keywords
composition according
composition
lipase
protease
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001561344A
Other languages
English (en)
Japanese (ja)
Other versions
JP5217050B2 (ja
JP2003524421A (ja
Filing date
Publication date
Priority claimed from US09/791,947 external-priority patent/US20010046493A1/en
Application filed filed Critical
Publication of JP2003524421A publication Critical patent/JP2003524421A/ja
Publication of JP2003524421A5 publication Critical patent/JP2003524421A5/ja
Application granted granted Critical
Publication of JP5217050B2 publication Critical patent/JP5217050B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2001561344A 2000-02-24 2001-02-23 リパーゼ含有組成物およびこれらの使用方法 Expired - Fee Related JP5217050B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18451700P 2000-02-24 2000-02-24
US60/184,517 2000-02-24
US09/791,947 2001-02-22
US09/791,947 US20010046493A1 (en) 2000-02-24 2001-02-22 Lipase-containing composition and methods of use thereof
PCT/US2001/006074 WO2001062280A2 (en) 2000-02-24 2001-02-23 Lipase-containing composition and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011260721A Division JP2012040028A (ja) 2000-02-24 2011-11-29 リパーゼ含有組成物およびこれらの使用方法

Publications (3)

Publication Number Publication Date
JP2003524421A JP2003524421A (ja) 2003-08-19
JP2003524421A5 true JP2003524421A5 (cg-RX-API-DMAC10.html) 2008-04-03
JP5217050B2 JP5217050B2 (ja) 2013-06-19

Family

ID=26880199

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001561344A Expired - Fee Related JP5217050B2 (ja) 2000-02-24 2001-02-23 リパーゼ含有組成物およびこれらの使用方法
JP2011260721A Pending JP2012040028A (ja) 2000-02-24 2011-11-29 リパーゼ含有組成物およびこれらの使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011260721A Pending JP2012040028A (ja) 2000-02-24 2011-11-29 リパーゼ含有組成物およびこれらの使用方法

Country Status (11)

Country Link
US (4) US20010046493A1 (cg-RX-API-DMAC10.html)
EP (1) EP1261368B1 (cg-RX-API-DMAC10.html)
JP (2) JP5217050B2 (cg-RX-API-DMAC10.html)
AT (1) ATE465748T1 (cg-RX-API-DMAC10.html)
AU (1) AU2001249072B2 (cg-RX-API-DMAC10.html)
DE (1) DE60141950D1 (cg-RX-API-DMAC10.html)
DK (1) DK1261368T3 (cg-RX-API-DMAC10.html)
ES (1) ES2345032T3 (cg-RX-API-DMAC10.html)
IL (1) IL151313A0 (cg-RX-API-DMAC10.html)
PT (1) PT1261368E (cg-RX-API-DMAC10.html)
WO (1) WO2001062280A2 (cg-RX-API-DMAC10.html)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
AU2002364750A1 (en) * 2001-12-14 2003-06-30 Solvay Pharmaceuticals Gmbh Use of digestive enzyme mixtures for treating pathological bacterial overgrowth of the small intestine of mammals and humans
EP1350435B1 (en) 2002-04-05 2010-12-22 Societe Des Produits Nestle S.A. Compositions and methods for promoting lipid assimilation in pets
KR20040012305A (ko) * 2002-08-02 2004-02-11 김영권 리파아제를 생산능을 가지는 신규한 불콜데리아멀티보란스 dh4와 이를 이용한 리파아제 생산방법
FR2848847B1 (fr) * 2002-12-18 2005-10-14 Coletica Composition cosmetique ou dermopharmaceutique comprenant une enzyme insoluble en milieu aqueux, ainsi que ses utilisations
ES2421538T3 (es) * 2003-10-29 2013-09-03 Cystic Fibrosis Foundation Therapeutics Inc Proteasas no pancreáticas para controlar la concentración de colecistocinina (CCK) en plasma y para tratar el dolor
JP2005222035A (ja) * 2004-01-09 2005-08-18 Canon Inc 電子写真画像形成装置
JP4931603B2 (ja) * 2004-01-28 2012-05-16 シーエスアイアール 酵素の安定化
CA2560613C (en) * 2004-03-22 2015-11-24 Solvay Pharmaceuticals Gmbh Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants
CN1997352B (zh) * 2004-06-17 2010-12-01 天野酶制品美国有限公司 含粘膜粘附性聚合物的酶、微生物和抗体的控释制剂
DK1809320T3 (da) * 2004-10-14 2010-11-15 Cystic Fibrosis Foundation The Præparater indeholdende lipase, protease og amylase til behandling af pankreatisk insufficiens
CA2610159C (en) * 2005-06-10 2015-03-31 Altus Pharmaceuticals Inc. Methods to reduce oxalate concentration by administration of oxalate oxidase crystals
EP1896057A2 (en) 2005-06-24 2008-03-12 Novozymes A/S Amylases for pharmaceutical use
PL2278002T3 (pl) * 2005-07-29 2017-12-29 Abbott Laboratories Gmbh Pankreatyna o zmniejszonej zawartości wirusowej
US9198871B2 (en) * 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
WO2007053619A2 (en) * 2005-11-01 2007-05-10 Bio-Cat, Inc. A composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrous as well as people suffering from pancreatic lipase insufficiency
US10072256B2 (en) * 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US20080199448A1 (en) * 2007-02-16 2008-08-21 Ross Mairi R Enzyme composition for improving food digestion
PT2079445E (pt) * 2007-02-20 2016-02-29 Allergan Pharmaceuticals Internat Ltd Composições de enzimas digestivas estáveis
ES2748136T3 (es) 2007-10-15 2020-03-13 United Animal Health Inc Método para aumentar el rendimiento de las crías
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
WO2009109856A2 (en) 2008-03-07 2009-09-11 Axcan Pharma Inc. Method for detecting infectious parvovirus in pharmaceutical preparations
DE102009006594A1 (de) 2009-01-29 2010-08-05 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutisches Präparat
BRPI0922653B8 (pt) * 2009-01-29 2021-05-25 Nordmark Arzneimittel Gmbh & Co Kg uso de uma lipase bacteriana do tipo pseudomonas em solução aquosa
US8784884B2 (en) 2009-09-17 2014-07-22 Stephen Perrett Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency
SE535296C2 (sv) * 2010-09-08 2012-06-19 Anara Ab Mognad av mag-tarmkanalen
EA029101B1 (ru) 2010-10-01 2018-02-28 Апталис Фарма Лимитид Составы с низкой дозой панкрелипазы и кишечнорастворимым покрытием
CA2843556A1 (en) 2011-08-08 2013-02-14 Aptalis Pharma Ltd. Method for dissolution testing of solid compositions containing digestive enzymes
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
PL3398594T3 (pl) 2012-09-19 2024-11-04 Grespo Ab Kompozycje do ulepszenia funkcji mózgu
WO2014141121A1 (en) 2013-03-15 2014-09-18 Aptalis Pharma Ltd. Composition containing digestive enzymes and nutrients suitable for enteral administration
CA2919114A1 (en) 2013-07-22 2015-02-12 Aptalis Pharma Ltd. High potency pancreatin pharmaceutical compositions
EP3639846B1 (en) 2013-08-09 2022-09-28 Allergan Pharmaceuticals International Limited Digestive enzyme composition suitable for enteral administration
EP3003360B1 (en) 2013-11-05 2020-10-07 Allergan Pharmaceuticals International Limited High potency pancreatin pharmaceutical compositions
EP3157568A1 (en) 2014-06-19 2017-04-26 Aptalis Pharma Limited Methods for removing viral contaminants from pancreatic extracts
GB201501081D0 (en) 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion
US20180028454A1 (en) * 2015-02-04 2018-02-01 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
CN107922897A (zh) 2015-08-28 2018-04-17 荷兰联合利华有限公司 包含蛋白酶和非蛋白酶的酶的液体洗涤组合物
DE102015114857A1 (de) 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung
US10560349B2 (en) 2018-01-31 2020-02-11 Salesforce.Com, Inc. Data consistency of policy enforcement for distributed applications
BR112022003705A2 (pt) * 2019-08-30 2022-05-24 Codexis Inc Lipase recombinante, composição, sequência de polinucleotídeo recombinante, vetor de expressão, composição farmacêutica para o tratamento de insuficiência pancreática, célula hospedeira, métodos para produzir uma lipase recombinante e para tratar e/ou prevenir os sintomas de insuficiência pancreática, e, uso

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3944470A (en) * 1973-06-29 1976-03-16 The Procter & Gamble Company Stabilization and enhancement of enzymatic activity
GB1509866A (en) * 1975-06-10 1978-05-04 Johnson & Johnson Enteric coated digestive enzyme compositions
US4659667A (en) * 1985-02-26 1987-04-21 Miles Laboratories, Inc. Process to recover crystalline enzymes and crystalline enzymes produced thereby
DK154572C (da) * 1985-08-07 1989-04-24 Novo Industri As Enzymatisk detergentadditiv, detergent og fremgangsmaade til vask af tekstiler
JP3079276B2 (ja) * 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
DE3808695A1 (de) * 1988-03-16 1989-10-05 Henkel Kgaa Fluessiges waschmittel
DK173590D0 (da) * 1990-06-06 1990-07-19 Novo Nordisk As Rekombinante terapeutiske lipaser
US5618710A (en) * 1990-08-03 1997-04-08 Vertex Pharmaceuticals, Inc. Crosslinked enzyme crystals
US5892013A (en) * 1990-09-13 1999-04-06 Novo Nordisk A/S Lipase variants
CA2110497C (en) * 1991-07-01 2005-04-19 Reinhard Braatz Use of bacterial lipases for producing drugs for maldigestion therapy
WO1993013200A1 (en) * 1991-12-20 1993-07-08 Novo Nordisk A/S A process for the preparation of lipase
SG42846A1 (en) * 1992-06-30 1997-10-17 Cortecs Ltd Use of enzymes especially bromelain in the treatment of diarrhoea
DK154292D0 (da) * 1992-12-23 1992-12-23 Novo Nordisk As Nyt enzym
DK39693D0 (da) * 1993-04-02 1993-04-02 Novo Nordisk As Enzym
US6051020A (en) * 1994-02-09 2000-04-18 Boston Scientific Technology, Inc. Bifurcated endoluminal prosthesis
GB9403344D0 (en) * 1994-02-22 1994-04-13 Cortecs Ltd Medical application of bromelain
DE4408152A1 (de) * 1994-03-11 1995-09-14 Studiengesellschaft Kohle Mbh Immobilisierte Lipasen in hydrophoben Sol-Gel-Materialien
AU2524695A (en) * 1994-05-04 1995-11-29 Genencor International, Inc. Lipases with improved surfactant resistance
JPH08143469A (ja) * 1994-11-14 1996-06-04 Amano Pharmaceut Co Ltd 膵外分泌機能不全症治療剤
JPH08264685A (ja) * 1995-03-27 1996-10-11 Toshiba Corp 樹脂封止型半導体装置及びその製造方法
DE69634248T2 (de) * 1995-05-31 2006-01-12 Medzyme N.V. Zusammensetzungen zur verbesserung der verdaulichkeit und ausnutzung von nähestoffen
US5932212A (en) * 1996-05-24 1999-08-03 Altus Biologics, Inc. Crosslinked protein crystal formulations and their use as catalysts in organic solvents
US5750104A (en) * 1996-05-29 1998-05-12 Digestive Care Inc. High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith
US5843296A (en) * 1996-12-26 1998-12-01 Digital Matrix Method for electroforming an optical disk stamper
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US6013680A (en) * 1997-10-21 2000-01-11 Amano Pharmaceutical Co., Ltd. Digestive enzyme-containing medicament
US6541606B2 (en) * 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
US6156552A (en) * 1998-02-18 2000-12-05 Novo Nordisk A/S Lipase variants
EP2311436A1 (en) * 1998-04-27 2011-04-20 Altus Pharmaceuticals Inc. Stabilized protein crystals, formulations containing them and methods of making them
US6042823A (en) * 1998-07-02 2000-03-28 Amano Pharmaceuticals Co., Ltd. Enzyme composition and use thereof
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
AR032392A1 (es) * 2001-01-19 2003-11-05 Solvay Pharm Gmbh Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado.
DK1809320T3 (da) * 2004-10-14 2010-11-15 Cystic Fibrosis Foundation The Præparater indeholdende lipase, protease og amylase til behandling af pankreatisk insufficiens

Similar Documents

Publication Publication Date Title
CA2228389C (en) High buffer-containing enteric coated digestive enzyme bile-acid compositions and method of treating digestive disorders therewith
World Health Organization Meningococcal meningitis: Overview= Méningite à méningocoques: Généralités
DeGroot et al. Encapsulation of urease in alginate beads and protection from α-chymotrypsin with chitosan membranes
DE69808402D1 (de) Arzneimittel zur Behandlung von durch Hernie gestörter intervertebraler Bandscheibe
US20030096791A1 (en) Taste masking of highly water-soluble drugs
JP2005504804A (ja) 中耳感染を処置する方法
IL173078A0 (en) Multiparticle pharmaceutical dosage form containing a mucoadhesively formulated peptide or protein active substances method for producing said pharmaceutical dosage form
DE60202794D1 (de) Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür
AU2223095A (en) Effervescent pharmaceutical formulations containing controlled release biodegradable microcapsules
EP0954290A1 (fr) Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
EP1663177B1 (en) Topical preparations comprising a hydrophilic carrier and a silicone matrix
JP2013522284A (ja) 胃耐性の酵素医薬組成物
IL154731A0 (en) Ion-strength independent sustained release pharmaceutical formulation
NO20023464L (no) Sammensetning for intestinal avlevering
CA3055116C (en) Orodispersible tablet containing burlulipase and pharmaceutical composition produced therefrom
JP7554807B2 (ja) 消化障害の予防および/または処置用の医薬組成物およびそれを製造する方法、並びにそれを含む医薬製品
AU5802299A (en) Extended release acetaminophen
CN117860718A (zh) 金刚烷胺组合物、其制备和使用方法
CA2386547A1 (en) Orally disintegrating composition comprising mirtazapine
GB2398005A (en) Orally administrable pharmaceutical formulation
EP0387945B1 (en) A composition for the treatment of exocrine insufficiency of the pancreas, and the use of said composition
CA3055118C (en) Pharmaceutical composition comprising pancreatin and a lipase-containing coating
RU2172170C2 (ru) Лекарственное средство для улучшения пищеварения
WO2004037226B1 (en) Pharmaceutical compositions containing venlafaxine
JP2006342152A (ja) 抗アレルギー組成物