DE60202794D1 - Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür - Google Patents

Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür

Info

Publication number
DE60202794D1
DE60202794D1 DE60202794T DE60202794T DE60202794D1 DE 60202794 D1 DE60202794 D1 DE 60202794D1 DE 60202794 T DE60202794 T DE 60202794T DE 60202794 T DE60202794 T DE 60202794T DE 60202794 D1 DE60202794 D1 DE 60202794D1
Authority
DE
Germany
Prior art keywords
agent
excipients
grains
microgranules
seconds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60202794T
Other languages
English (en)
Other versions
DE60202794T2 (de
Inventor
Edouard Gendrot
Nourredine Nouri
Pascal Suplie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethypharm SAS
Original Assignee
Ethypharm SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm SAS filed Critical Ethypharm SAS
Publication of DE60202794D1 publication Critical patent/DE60202794D1/de
Application granted granted Critical
Publication of DE60202794T2 publication Critical patent/DE60202794T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE60202794T 2001-11-05 2002-10-28 Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür Expired - Lifetime DE60202794T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0114269 2001-11-05
FR0114269A FR2831820B1 (fr) 2001-11-05 2001-11-05 Comprime orodispersible presentant une grande homogeneite et son procede de preparation
PCT/FR2002/003690 WO2003039520A1 (fr) 2001-11-05 2002-10-28 Comprime orodispersible presentant une grande homogeneite et son procede de preparation

Publications (2)

Publication Number Publication Date
DE60202794D1 true DE60202794D1 (de) 2005-03-03
DE60202794T2 DE60202794T2 (de) 2006-05-18

Family

ID=8869063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60202794T Expired - Lifetime DE60202794T2 (de) 2001-11-05 2002-10-28 Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür

Country Status (10)

Country Link
US (1) US20050019391A1 (de)
EP (1) EP1441704B1 (de)
JP (2) JP4749668B2 (de)
AT (1) ATE287704T1 (de)
CA (1) CA2465753C (de)
DE (1) DE60202794T2 (de)
DK (1) DK1441704T3 (de)
ES (1) ES2236617T3 (de)
FR (1) FR2831820B1 (de)
WO (1) WO2003039520A1 (de)

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US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
DE60124895D1 (de) * 2001-07-26 2007-01-11 Ethypharm Sa Umgehüllte Allylamine oder Benzylamine enthaltende Granulate, Verfahren zur Herstellung und in der Mundhöhle dispergierbare Tabletten enthaltend die umgehüllten Granulate
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
FR2831820B1 (fr) * 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
PL1689378T3 (pl) 2003-12-02 2009-09-30 Sanol Arznei Schwarz Gmbh Nowe zastosowanie związków peptydowych do leczenia ośrodkowego bólu neuropatycznego
EP1604655A1 (de) 2004-06-09 2005-12-14 Schwarz Pharma Ag Neue Verwendung von Peptidverbindungen zur Behandlung von Trigeminusneuralgie
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
US20060105039A1 (en) 2004-10-21 2006-05-18 Jin-Wang Lai Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US8735356B2 (en) 2006-06-15 2014-05-27 Ucb Pharma Gmbh Anticonvulsant combination therapy
CN101505613B (zh) 2006-08-17 2012-07-18 古木林科有限公司 树脂包封的强力甜味剂
ES2646112T3 (es) * 2007-06-06 2017-12-12 Basf Se Formulación farmacéutica para la fabricación de comprimidos que se desintegran rápidamente
US8685457B2 (en) * 2007-06-06 2014-04-01 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
ES2639130T3 (es) * 2007-06-06 2017-10-25 Basf Se Formulación farmacéutica para la fabricación de comprimidos de rápida desintegración
US20100184785A1 (en) * 2007-06-06 2010-07-22 Basf Se Pharmaceutical formulation for the production of chewable tablets and lozenges
CA2725578A1 (en) * 2008-04-24 2009-10-29 Evestra, Inc. Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
EP2385769A4 (de) * 2008-12-15 2014-08-20 Valeant Pharmaceuticals Luxembourg S R L Schnell lösliche vitaminformulierung und verfahren zu ihrer anwendung
EP2405905B1 (de) * 2009-03-09 2016-06-29 SPI Pharma, INC. Hoch verdichtungsfähige und beständige direktkompressionshilfsstoffe und hilfsstoffsysteme
US9113161B2 (en) * 2009-04-14 2015-08-18 Panasonic Intellectual Property Management Co., Ltd. Video display apparatus, video viewing glasses, and system comprising the display apparatus and the glasses
UA118087C2 (uk) 2009-10-01 2018-11-26 Адер Фармасьютікалз, Інк. Композиція кортикостероїду, застосована перорально
CN102958515A (zh) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 非索非那定微胶囊及含有非索非那定微胶囊的组合物
WO2011112771A1 (en) * 2010-03-11 2011-09-15 Rich Vitamins Llc Quick dissolve nutritional powder
FR2962331B1 (fr) 2010-07-06 2020-04-24 Ethypharm Forme pharmaceutique pour lutter contre la soumission chimique, methode la mettant en oeuvre
FR2962550B1 (fr) 2010-07-06 2013-06-14 Ethypharm Sa Methode pour lutter contre la soumission chimique, utilisation d'agent colorant pour lutter contre la soumission chimique et composition pharmaceutique permettant la mise en oeuvre de la methode
FR2999432B1 (fr) 2012-12-17 2014-12-12 Ethypharm Sa Comprimes orodispersibles obtenus par compression moulage
WO2015034678A2 (en) * 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
TWI777515B (zh) 2016-08-18 2022-09-11 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法

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FR2236483B1 (de) * 1973-07-12 1976-11-12 Choay Sa
US4199610A (en) * 1978-09-13 1980-04-22 The Procter & Gamble Company Non-hygroscopic dry instant beverage mixes
WO1981002671A1 (en) * 1980-03-20 1981-10-01 Ferring Farma Lab Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease by oral administration
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
RU2147227C1 (ru) * 1994-01-31 2000-04-10 Яманоути Фармасьютикал Ко., Лтд. Растворяющиеся внутри ротовой полости изделия, сформованные прессованием, и способ их производства
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
EP1380308B1 (de) * 1996-07-12 2008-07-09 Daiichi Pharmaceutical Co., Ltd. Schnell zerfallende, druckgeformte Materialien sowie Prozess zu deren Herstellung
JP4939680B2 (ja) * 1997-05-27 2012-05-30 武田薬品工業株式会社 固形製剤
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
US6270790B1 (en) * 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability
FR2784895B1 (fr) * 1998-10-23 2004-12-17 Gattefosse Ets Sa Comprime a croquer a gout masque et liberation immediate du principe actif et procede de fabrication
JP2000178183A (ja) * 1998-12-17 2000-06-27 Lion Corp 固形製剤及びその製造方法
FR2790387B1 (fr) * 1999-03-01 2001-05-18 Prographarm Laboratoires Comprime orodispersible presentant une faible friabilite et son procede de preparation
JP2001058944A (ja) * 1999-06-18 2001-03-06 Takeda Chem Ind Ltd 速崩壊性固形製剤
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
FR2831820B1 (fr) * 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation

Also Published As

Publication number Publication date
JP2011006482A (ja) 2011-01-13
DK1441704T3 (da) 2005-05-30
EP1441704A1 (de) 2004-08-04
US20050019391A1 (en) 2005-01-27
WO2003039520A1 (fr) 2003-05-15
FR2831820A1 (fr) 2003-05-09
ATE287704T1 (de) 2005-02-15
DE60202794T2 (de) 2006-05-18
JP2005511589A (ja) 2005-04-28
CA2465753C (fr) 2013-05-14
FR2831820B1 (fr) 2004-08-20
EP1441704B1 (de) 2005-01-26
ES2236617T3 (es) 2005-07-16
CA2465753A1 (fr) 2003-05-15
JP4749668B2 (ja) 2011-08-17

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Legal Events

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