JP2003522167A5 - - Google Patents
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- JP2003522167A5 JP2003522167A5 JP2001557859A JP2001557859A JP2003522167A5 JP 2003522167 A5 JP2003522167 A5 JP 2003522167A5 JP 2001557859 A JP2001557859 A JP 2001557859A JP 2001557859 A JP2001557859 A JP 2001557859A JP 2003522167 A5 JP2003522167 A5 JP 2003522167A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Description
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17979400P | 2000-02-02 | 2000-02-02 | |
US60/179,794 | 2000-02-02 | ||
PCT/US2001/003385 WO2001057027A1 (en) | 2000-02-02 | 2001-02-02 | C7 ester substituted taxanes as antitumor agents |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2003522167A JP2003522167A (ja) | 2003-07-22 |
JP2003522167A5 true JP2003522167A5 (ja) | 2007-03-15 |
Family
ID=22658029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001557859A Pending JP2003522167A (ja) | 2000-02-02 | 2001-02-02 | 抗腫瘍剤としてのc7エステル置換タキサン |
Country Status (35)
Country | Link |
---|---|
US (3) | US6610860B2 (ja) |
EP (1) | EP1183253B8 (ja) |
JP (1) | JP2003522167A (ja) |
KR (1) | KR100784161B1 (ja) |
CN (1) | CN1362955A (ja) |
AR (1) | AR030188A1 (ja) |
AT (1) | ATE396188T1 (ja) |
AU (1) | AU776051B2 (ja) |
BG (1) | BG65279B1 (ja) |
BR (1) | BR0104749A (ja) |
CA (1) | CA2368993C (ja) |
CO (1) | CO5280224A1 (ja) |
CZ (1) | CZ298484B6 (ja) |
DE (1) | DE60134094D1 (ja) |
DK (1) | DK1183253T3 (ja) |
ES (1) | ES2307588T3 (ja) |
GE (1) | GEP20043322B (ja) |
HK (1) | HK1047938A1 (ja) |
HU (1) | HUP0200917A3 (ja) |
IL (1) | IL145641A0 (ja) |
MX (1) | MXPA01009901A (ja) |
MY (1) | MY137637A (ja) |
NO (1) | NO327982B1 (ja) |
NZ (1) | NZ514409A (ja) |
PL (1) | PL202668B1 (ja) |
PT (1) | PT1183253E (ja) |
RO (1) | RO121777B1 (ja) |
RU (1) | RU2265017C2 (ja) |
SA (1) | SA01220045B1 (ja) |
SK (1) | SK13712001A3 (ja) |
TR (1) | TR200102856T1 (ja) |
TW (1) | TWI291873B (ja) |
UA (1) | UA75573C2 (ja) |
WO (1) | WO2001057027A1 (ja) |
ZA (1) | ZA200108060B (ja) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003521545A (ja) * | 2000-02-02 | 2003-07-15 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | 改良された溶解性を有するタキサン製剤 |
CO5280224A1 (es) | 2000-02-02 | 2003-05-30 | Univ Florida State Res Found | Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen |
CA2354486A1 (en) * | 2001-07-31 | 2003-01-31 | Florida State University Research Foundation, Inc. | C7 ester substituted taxanes |
SG125889A1 (en) * | 2001-08-01 | 2006-10-30 | Univ Florida State Res Found | C7 ester subsituted taxanes |
KR100819578B1 (ko) * | 2001-08-01 | 2008-04-04 | 플로리다 스테이트 유니버시티 리서치 파운데이션, 인크 | C7 에스테르 치환된 탁산 |
US20030082229A1 (en) * | 2001-11-01 | 2003-05-01 | Board Of Regents, The University Of Texas Systems | Parenteral chlorambucil for treatment of malignant and autoimmune disease and methods of use |
US8012950B2 (en) * | 2003-08-29 | 2011-09-06 | Wisconsin Alumni Research Foundation | Method to diagnose and treat degenerative joint disease |
EP1894921A3 (en) * | 2003-09-25 | 2008-03-12 | Tapestry Pharmaceuticals, Inc. | 9, 10-Alpha, Alpha-Oh-Taxane analogs and methods for production thereof |
ATE377593T1 (de) | 2003-09-25 | 2007-11-15 | Tapestry Pharmaceuticals Inc | 9,10-alpha,alpha-oh-taxananaloga und verfahren zu deren herstellung |
JP2007527432A (ja) * | 2004-03-05 | 2007-09-27 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | C7ラクチルオキシ置換タキサン |
TW200533339A (en) * | 2004-03-16 | 2005-10-16 | Bristol Myers Squibb Co | Therapeutic synergy of anti-cancer compounds |
EP1812864A2 (en) * | 2004-10-07 | 2007-08-01 | Emory University | Multifunctional nanoparticles conjugates and their use |
NZ589418A (en) | 2004-10-25 | 2012-03-30 | Dekk Tec Inc | Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents |
US20060216767A1 (en) * | 2005-03-22 | 2006-09-28 | Saladax Biomedical Inc. | Docetaxel immunoassay |
PL217731B1 (pl) | 2006-06-01 | 2014-08-29 | Tomasz Byrski | Sposób wykrywania genetycznie uwarunkowanej obniżonej odpowiedzi na chemioterapię cytostatykiem taksanowym, zastosowanie mutacji założycielskiej oraz zestawu do wykrywania takiej odpowiedzi |
US11786504B2 (en) | 2006-09-28 | 2023-10-17 | Tapestry Pharmaceuticals, Inc. | Taxane analogs for the treatment of brain cancer |
WO2008106621A1 (en) | 2007-02-28 | 2008-09-04 | Tapestry Pharmaceuticals, Inc | Taxane analogs for the treatment of brain cancer |
WO2008121476A1 (en) | 2007-03-28 | 2008-10-09 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
US11873308B2 (en) | 2006-11-06 | 2024-01-16 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
EP2118079A1 (en) | 2007-02-07 | 2009-11-18 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Synthetic macrocyclic compounds for treating cancer |
EP2581367B1 (en) | 2007-04-06 | 2015-12-30 | Ziopharm Oncology, Inc. | Salts of isophosphoramide mustard and analogs thereof |
CA2732290A1 (en) | 2008-07-31 | 2010-02-04 | Ziopharm Oncology, Inc. | Synthesis and formulations of salts of isophosphoramide mustard and analogs thereof |
CA2753041A1 (en) | 2009-02-24 | 2010-09-02 | Dekk-Tec, Inc. | Complexes of 4-hydroperoxy ifosfamide as anti-tumor agents |
WO2010138686A1 (en) | 2009-05-29 | 2010-12-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mdri-inverse agents |
WO2011112867A1 (en) | 2010-03-10 | 2011-09-15 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | The use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas |
WO2012033601A1 (en) | 2010-08-20 | 2012-03-15 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Thiosemicarbazones with mdr1 - inverse activity |
ES2718812T3 (es) | 2011-07-11 | 2019-07-04 | Us Health | Conjugados de anticuerpo-fluoróforo fotosensibilizantes |
AU2013266235B2 (en) | 2012-05-25 | 2017-06-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of regulating cannabinoid receptor activity-related disorders and diseases |
ES2764833T3 (es) | 2013-10-11 | 2020-06-04 | The United States Of America Represented By The Sec Dep Of Health And Human Services | Anticuerpos contra TEM8 y su uso |
SG11201610052TA (en) | 2014-08-08 | 2017-02-27 | Us Health | Photo-controlled removal of targets in vitro and in vivo |
WO2019099615A1 (en) | 2017-11-17 | 2019-05-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of copeptin to modulate the immune response and hematopoiesis, and stimulate bone growth |
JP2021521135A (ja) | 2018-04-10 | 2021-08-26 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | がん細胞を標的とする近赤外光線免疫療法および宿主免疫活性化の組合せ |
EA202290208A1 (ru) | 2019-07-02 | 2022-03-25 | Дзе Юнайтед Стейтс Оф Эмерика, Эз Репрезентед Бай Дзе Секретэри, Дипартмент Оф Хелт Энд Хьюман Сервисиз | МОНОКЛОНАЛЬНЫЕ АНТИТЕЛА, КОТОРЫЕ СВЯЗЫВАЮТ EGFRvIII, И ИХ ПРИМЕНЕНИЕ |
US20230057461A1 (en) | 2020-01-27 | 2023-02-23 | The U.S.A., As Represented By The Secretary, Department Of Health And Human Services | Rab13 and net1 antisense oligonucleotides to treat metastatic cancer |
EP4284439A1 (en) | 2021-01-29 | 2023-12-06 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Near infrared photoimmunotherapy (nir-pit) combination therapy to treat cancer |
IL308018A (en) | 2021-04-30 | 2023-12-01 | Kalivir Immunotherapeutics Inc | Oncolytic viruses for different MHC expression |
WO2024006965A1 (en) | 2022-06-30 | 2024-01-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cd25-specific antibodies and uses thereof |
Family Cites Families (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5321128A (en) * | 1988-09-06 | 1994-06-14 | Kabi Pharmacia Ab | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
SE463189B (sv) | 1989-03-13 | 1990-10-22 | Eston Joensson | Preparat avsett att tillfoeras amalgamfyllningar i taender foer att daerigenom hindra eller minska avgaang av kvicksilver eller kvicksilveraanga |
US5175315A (en) | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
FR2679230B1 (fr) | 1991-07-16 | 1993-11-19 | Rhone Poulenc Rorer Sa | Nouveaux derives d'analogues du taxol, leur preparation et les compositions qui les contiennent. |
US5243045A (en) | 1991-09-23 | 1993-09-07 | Florida State University | Certain alkoxy substituted taxanes and pharmaceutical compositions containing them |
US5489601A (en) * | 1991-09-23 | 1996-02-06 | Florida State University | Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them |
US5227400A (en) | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
US5714513A (en) | 1991-09-23 | 1998-02-03 | Florida State University | C10 taxane derivatives and pharmaceutical compositions |
US5430160A (en) | 1991-09-23 | 1995-07-04 | Florida State University | Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides |
US5350866A (en) | 1991-09-23 | 1994-09-27 | Bristol-Myers Squibb Company | 10-desacetoxytaxol derivatives |
US5283253A (en) | 1991-09-23 | 1994-02-01 | Florida State University | Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them |
US5721268A (en) | 1991-09-23 | 1998-02-24 | Florida State University | C7 taxane derivatives and pharmaceutical compositions containing them |
DE69333675T2 (de) | 1992-01-15 | 2006-02-02 | E.R. Squibb & Sons, Inc. | Enzymatische Verfahren zur Trennung von Enantiomerengemischen von Verbindungen, die als Zwischenprodukte zur Herstellung von Taxanen nützlich sind |
US5272171A (en) | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
US5200534A (en) | 1992-03-13 | 1993-04-06 | University Of Florida | Process for the preparation of taxol and 10-deacetyltaxol |
ATE181551T1 (de) | 1992-04-17 | 1999-07-15 | Abbott Lab | Taxol-derivate |
US5248796A (en) | 1992-06-18 | 1993-09-28 | Bristol-Myers Squibb Company | Taxol derivatives |
US5319112A (en) | 1992-08-18 | 1994-06-07 | Virgnia Tech Intellectual Properties, Inc. | Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol |
WO1994005282A1 (en) | 1992-09-04 | 1994-03-17 | The Scripps Research Institute | Water soluble taxol derivatives |
CA2100808A1 (en) | 1992-10-01 | 1994-04-02 | Vittorio Farina | Deoxy paclitaxels |
KR100378612B1 (ko) | 1992-12-23 | 2003-04-03 | 브리스톨-마이어스스퀴브컴파니 | 신규 측쇄-함유 탁산 및 그의 중간체 화합물 |
IL108443A0 (en) * | 1993-01-29 | 1994-04-12 | Univ Florida State | C7 taxane derivatives and pharmaceutical compositions containing them |
US5703247A (en) | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
ES2164100T3 (es) * | 1993-03-22 | 2002-02-16 | Univ Florida State | Taxanos con una cadena lateral de piridina sustituida. |
EP0689436B1 (en) * | 1993-03-22 | 2003-11-26 | Florida State University | Taxanes not having an oxo group at c-9 and pharmaceutical compositions containing same |
ATE195421T1 (de) * | 1993-03-22 | 2000-09-15 | Univ Florida State | Taxane mit amino-substituierter seitenkette |
ATE249448T1 (de) | 1993-06-11 | 2003-09-15 | Upjohn Co | Delta 6,7-taxol derivate antineoplastische verbindungen und diese enthaltende pharmazeutische zusammenstellungen |
IL109926A (en) | 1993-06-15 | 2000-02-29 | Bristol Myers Squibb Co | Methods for the preparation of taxanes and microorganisms and enzymes utilized therein |
TW397866B (en) | 1993-07-14 | 2000-07-11 | Bristol Myers Squibb Co | Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes |
FR2711369B1 (fr) | 1993-10-20 | 1995-11-17 | Rhone Poulenc Rorer Sa | Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent. |
US5415869A (en) | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
US5414869A (en) * | 1993-11-26 | 1995-05-16 | Thomson; Margaret I. | Knotless scarf and method of making same |
WO1996013495A1 (en) * | 1994-10-28 | 1996-05-09 | The Research Foundation Of State University Of New York | Taxoid derivatives, their preparation and their use as antitumor agents |
TW354293B (en) | 1995-06-06 | 1999-03-11 | Bristol Myers Squibb Co | Prodrugs of paclitaxel derivatives |
US5780653A (en) | 1995-06-07 | 1998-07-14 | Vivorx Pharmaceuticals, Inc. | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers |
CA2231837A1 (en) | 1995-09-13 | 1997-03-20 | Florida State University | Radiosensitizing taxanes and their pharmaceutical preparations |
US5767297A (en) | 1997-02-05 | 1998-06-16 | Ensuiko Sugar Refining Co., Ltd. | Taxoid derivative and method of producing thereof |
FR2745814B1 (fr) * | 1996-03-06 | 1998-04-03 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
WO1997042181A1 (en) | 1996-05-06 | 1997-11-13 | Florida State University | 1-deoxy baccatin iii, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof |
CA2254121A1 (en) * | 1996-05-17 | 1997-11-27 | Bruno Hancock | Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases |
US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
US6576636B2 (en) | 1996-05-22 | 2003-06-10 | Protarga, Inc. | Method of treating a liver disorder with fatty acid-antiviral agent conjugates |
DE69703294T2 (de) * | 1996-05-22 | 2001-05-17 | Protarga Inc | Zusammensetzungen die konjugate von cis-docosahexaenoic-säure und taxotere enthalten |
US5811452A (en) | 1997-01-08 | 1998-09-22 | The Research Foundation Of State University Of New York | Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof |
US5912264A (en) | 1997-03-03 | 1999-06-15 | Bristol-Myers Squibb Company | 6-halo-or nitrate-substituted paclitaxels |
US7288665B1 (en) | 1997-08-18 | 2007-10-30 | Florida State University | Process for selective derivatization of taxanes |
WO1999018113A1 (fr) * | 1997-10-08 | 1999-04-15 | Bio Research Corporation Of Yokohama | Derives taxoides et leur procede de production |
US6136988A (en) | 1998-04-10 | 2000-10-24 | Hauser, Inc. | 7-hexanoyltaxol and methods for preparing the same |
US5964739A (en) * | 1998-06-18 | 1999-10-12 | Champ; Raynido A. | Safety disposable needle structure |
US6146659A (en) * | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
EP1192126A1 (en) | 1999-06-21 | 2002-04-03 | Napro Biotherapeutics, Inc. | C-2 hydroxyl protected-n-acyl(2r,3s)-3-phenylisoserine activated esters and methods for production thereof |
WO2001025223A1 (en) * | 1999-10-06 | 2001-04-12 | The Research Foundation Of State University Of New York | Stabilization of taxane-containing dispersed systems |
BR0104358A (pt) | 2000-02-02 | 2002-01-02 | Univ Florida State Res Found | Formulações de taxana tendo solubilidade aperfeiçoada |
JP2003521545A (ja) * | 2000-02-02 | 2003-07-15 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | 改良された溶解性を有するタキサン製剤 |
CO5280224A1 (es) * | 2000-02-02 | 2003-05-30 | Univ Florida State Res Found | Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen |
IT1319168B1 (it) | 2000-03-17 | 2003-09-26 | Indena Spa | Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono. |
-
2001
- 2001-01-31 CO CO01007075A patent/CO5280224A1/es not_active Application Discontinuation
- 2001-01-31 AR ARP010100463A patent/AR030188A1/es not_active Application Discontinuation
- 2001-02-02 AT AT01905349T patent/ATE396188T1/de not_active IP Right Cessation
- 2001-02-02 MY MYPI20010481A patent/MY137637A/en unknown
- 2001-02-02 EP EP01905349A patent/EP1183253B8/en not_active Expired - Lifetime
- 2001-02-02 BR BR0104749-3A patent/BR0104749A/pt not_active IP Right Cessation
- 2001-02-02 RU RU2001129507/04A patent/RU2265017C2/ru not_active IP Right Cessation
- 2001-02-02 HU HU0200917A patent/HUP0200917A3/hu unknown
- 2001-02-02 CN CN01800306A patent/CN1362955A/zh active Pending
- 2001-02-02 DE DE60134094T patent/DE60134094D1/de not_active Expired - Fee Related
- 2001-02-02 IL IL14564101A patent/IL145641A0/xx unknown
- 2001-02-02 US US09/775,851 patent/US6610860B2/en not_active Expired - Fee Related
- 2001-02-02 PL PL350026A patent/PL202668B1/pl not_active IP Right Cessation
- 2001-02-02 UA UA2001106734A patent/UA75573C2/uk unknown
- 2001-02-02 WO PCT/US2001/003385 patent/WO2001057027A1/en active IP Right Grant
- 2001-02-02 RO ROA200101085A patent/RO121777B1/ro unknown
- 2001-02-02 MX MXPA01009901A patent/MXPA01009901A/es active IP Right Grant
- 2001-02-02 PT PT01905349T patent/PT1183253E/pt unknown
- 2001-02-02 CA CA002368993A patent/CA2368993C/en not_active Expired - Fee Related
- 2001-02-02 ES ES01905349T patent/ES2307588T3/es not_active Expired - Lifetime
- 2001-02-02 GE GE4514A patent/GEP20043322B/en unknown
- 2001-02-02 CZ CZ20013503A patent/CZ298484B6/cs not_active IP Right Cessation
- 2001-02-02 NZ NZ514409A patent/NZ514409A/xx unknown
- 2001-02-02 TR TR2001/02856T patent/TR200102856T1/xx unknown
- 2001-02-02 KR KR1020017012600A patent/KR100784161B1/ko not_active IP Right Cessation
- 2001-02-02 AU AU33239/01A patent/AU776051B2/en not_active Ceased
- 2001-02-02 JP JP2001557859A patent/JP2003522167A/ja active Pending
- 2001-02-02 DK DK01905349T patent/DK1183253T3/da active
- 2001-02-02 SK SK1371-2001A patent/SK13712001A3/sk unknown
- 2001-03-06 TW TW090102237A patent/TWI291873B/zh active
- 2001-04-11 SA SA1220045A patent/SA01220045B1/ar unknown
- 2001-10-01 ZA ZA200108060A patent/ZA200108060B/en unknown
- 2001-10-01 NO NO20014759A patent/NO327982B1/no not_active IP Right Cessation
- 2001-10-01 BG BG105967A patent/BG65279B1/bg unknown
-
2003
- 2003-01-07 HK HK03100173.6A patent/HK1047938A1/zh unknown
- 2003-06-25 US US10/606,027 patent/US7186849B2/en not_active Expired - Fee Related
-
2007
- 2007-01-09 US US11/621,321 patent/US20070249708A1/en not_active Abandoned