JP2003514872A - ワクチン組成物 - Google Patents
ワクチン組成物Info
- Publication number
- JP2003514872A JP2003514872A JP2001539483A JP2001539483A JP2003514872A JP 2003514872 A JP2003514872 A JP 2003514872A JP 2001539483 A JP2001539483 A JP 2001539483A JP 2001539483 A JP2001539483 A JP 2001539483A JP 2003514872 A JP2003514872 A JP 2003514872A
- Authority
- JP
- Japan
- Prior art keywords
- vaccine composition
- adjuvant
- hcv
- complex
- immunogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16665299P | 1999-11-19 | 1999-11-19 | |
| US60/166,652 | 1999-11-19 | ||
| US22436200P | 2000-08-11 | 2000-08-11 | |
| US60/224,362 | 2000-08-11 | ||
| PCT/AU2000/001410 WO2001037869A1 (en) | 1999-11-19 | 2000-11-17 | Vaccine compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003514872A true JP2003514872A (ja) | 2003-04-22 |
| JP2003514872A5 JP2003514872A5 (enExample) | 2007-11-01 |
Family
ID=26862451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001539483A Ceased JP2003514872A (ja) | 1999-11-19 | 2000-11-17 | ワクチン組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20040191270A1 (enExample) |
| EP (1) | EP1239876B1 (enExample) |
| JP (1) | JP2003514872A (enExample) |
| KR (1) | KR100875483B1 (enExample) |
| AT (1) | ATE402715T1 (enExample) |
| AU (1) | AU772617B2 (enExample) |
| CA (1) | CA2391843C (enExample) |
| DE (1) | DE60039715D1 (enExample) |
| ES (1) | ES2311478T3 (enExample) |
| HK (1) | HK1047892B (enExample) |
| NZ (2) | NZ518999A (enExample) |
| WO (1) | WO2001037869A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008511556A (ja) * | 2004-09-03 | 2008-04-17 | セントロ デ インジエニエリア ジエネテイカ イ バイオテクノロジア | C型肝炎ウイルスに対するワクチン組成物 |
| JP2014502959A (ja) * | 2010-11-26 | 2014-02-06 | ザ マクファーレーン バーネット インスティテュート フォー メディカル リサーチ アンド パブリック ヘルス リミテッド | 組成物および方法 |
| JP2014132030A (ja) * | 2014-04-08 | 2014-07-17 | Univ Of Melbourne:The | 免疫原性組成物およびその使用 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| DE60044236D1 (de) | 1999-02-17 | 2010-06-02 | Csl Ltd | Immunogene komplexe und methoden in bezug auf diese |
| ES2411096T3 (es) * | 1999-10-27 | 2013-07-04 | Novartis Vaccines And Diagnostics, Inc. | Activación de linfocitos T específicos contra el VHC |
| AU2002322358B2 (en) * | 2001-06-29 | 2009-06-18 | Novartis Vaccines And Diagnostics, Inc. | HCV E1E2 vaccine compositions |
| US20060210555A1 (en) * | 2001-12-21 | 2006-09-21 | Antigenics, Inc. | Compositions comprising immunoreactive reagents and saponins, and methods of use thereof |
| ES2339762T3 (es) * | 2002-01-14 | 2010-05-25 | Novartis Vaccines And Diagnostics, Inc. | Vacuna contra el vih y procedimiento de uso. |
| EP2263687B1 (en) | 2002-12-27 | 2015-03-25 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions containing phospholipid |
| AU2004228476A1 (en) * | 2003-04-11 | 2004-10-21 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Use of HCV proteins |
| JP2008506789A (ja) * | 2004-07-18 | 2008-03-06 | シーエスエル、リミテッド | インターフェロン−ガンマ応答強化を誘発するための免疫刺激複合体及びオリゴヌクレオチド処方物 |
| US20070190072A1 (en) * | 2004-09-30 | 2007-08-16 | Csl Limited Ludwig Institute For Cancer Research | In vivo efficacy of ny-eso-1 plus adjuvant |
| KR20070068460A (ko) * | 2004-10-18 | 2007-06-29 | 글로브이뮨 | 만성 c형 간염에 대한 효모계 치료 |
| ATE539079T1 (de) | 2006-03-23 | 2012-01-15 | Novartis Ag | Imidazochinoxalinverbindungen als immunmodulatoren |
| EP2200638B1 (en) * | 2007-10-09 | 2016-03-16 | The University of Melbourne | Compositions for the transfection of cells |
| SG185294A1 (en) * | 2007-10-12 | 2012-11-29 | Csl Ltd | Method of eliciting an immune response against pandemic influenza virus |
| EP2331125A4 (en) | 2008-09-19 | 2013-03-27 | Globeimmune Inc | IMMUNOTHERAPY FOR CHRONIC HEPATITIS C-VIRUS INFECTIONS |
| WO2010115229A1 (en) | 2009-04-09 | 2010-10-14 | The University Of Melbourne | Immunogenic composition and uses thereof |
| EP2563389B1 (en) | 2010-04-30 | 2015-07-08 | Temasek Life Sciences Laboratory Limited | Universal vaccine against h5n1 lineages |
| CA2811957C (en) | 2010-09-22 | 2019-04-16 | The University Of Melbourne | Soluble tlr2 moiety for use in the treatment or prevention of respiratory conditions associated with infectious agents |
| CU24112B1 (es) * | 2012-11-05 | 2015-08-27 | Ct De Ingeniería Genética Y Biotecnología | Antígenos vacunales quiméricos contra el virus de la hepatitis c |
| CN106749672B (zh) * | 2016-11-18 | 2020-06-30 | 江西农业大学 | 一种丙型肝炎病毒融合抗原蛋白及其应用 |
| IL275360B2 (en) | 2017-12-21 | 2023-10-01 | Axelia Oncology Pty Ltd | Optimal compounds |
| NZ783377A (en) | 2019-06-26 | 2026-03-27 | Ena Respiratory Pty Ltd | Pegylated novel molecules for agonising tlr2 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08510240A (ja) * | 1993-05-12 | 1996-10-29 | カイロン コーポレイション | C型肝炎ウイルスe2/ns1領域の保存モチーフ |
| JPH09503396A (ja) * | 1994-07-29 | 1997-04-08 | インノジェネティクス・エヌ・ブイ | 診断用及び治療用の精製c型肝炎ウイルスエンベロープ蛋白 |
| JPH10508301A (ja) * | 1994-10-12 | 1998-08-18 | イスコテック、アクチボラグ | サポニン製剤およびiscomでのその使用 |
| JPH11508769A (ja) * | 1995-06-29 | 1999-08-03 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | C型肝炎に対するワクチン |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8205892D0 (sv) * | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| US5897873A (en) * | 1984-04-12 | 1999-04-27 | The Liposome Company, Inc. | Affinity associated vaccine |
| US5583112A (en) * | 1987-05-29 | 1996-12-10 | Cambridge Biotech Corporation | Saponin-antigen conjugates and the use thereof |
| US5057540A (en) * | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| WO1990001947A1 (en) * | 1988-08-25 | 1990-03-08 | The Liposome Company, Inc. | Affinity associated vaccine |
| NZ230747A (en) * | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| US4981684A (en) * | 1989-10-24 | 1991-01-01 | Coopers Animal Health Limited | Formation of adjuvant complexes |
| US5178860A (en) * | 1989-09-01 | 1993-01-12 | Coopers Animal Health Limited | Adjuvant complexes and vaccine made therefrom |
| JP3507486B2 (ja) * | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5650398A (en) * | 1992-07-02 | 1997-07-22 | Cambridge Biotech Corporation | Drug delivery enhancement via modified saponins |
| US5273965A (en) * | 1992-07-02 | 1993-12-28 | Cambridge Biotech Corporation | Methods for enhancing drug delivery with modified saponins |
| JP3751315B2 (ja) * | 1993-05-05 | 2006-03-01 | コモン サーヴィシス エージェンシー | C型肝炎ウイルス4、5及び6型 |
| US5451569A (en) * | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
| US20030050263A1 (en) * | 1994-07-15 | 2003-03-13 | The University Of Iowa Research Foundation | Methods and products for treating HIV infection |
| US6239116B1 (en) * | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| AU686891B2 (en) * | 1994-10-12 | 1998-02-12 | Iscotec A.B. | Saponin preparations and use thereof in iscoms |
| GB9620795D0 (en) * | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
| SE9600648D0 (sv) * | 1996-02-21 | 1996-02-21 | Bror Morein | Receptorbimdande enhet |
| US6231859B1 (en) * | 1996-12-02 | 2001-05-15 | Aquila Biopharmaceuticals, Inc. | Saponin adjuvant compositions |
| US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| US6080725A (en) * | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
| EP1003531B1 (en) * | 1997-05-20 | 2007-08-22 | Ottawa Health Research Institute | Processes for preparing nucleic acid constructs |
| NZ500779A (en) * | 1997-05-20 | 2001-06-29 | Galenica Pharmaceuticals Inc | Triterpene saponin analogs having adjuvant and immunostimulatory activity |
| EP1279401B1 (en) * | 1997-09-05 | 2008-01-09 | GlaxoSmithKline Biologicals S.A. | Oil in water emulsions containing saponins |
| GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| US20050031638A1 (en) * | 1997-12-24 | 2005-02-10 | Smithkline Beecham Biologicals S.A. | Vaccine |
| DK1077722T3 (da) * | 1998-05-22 | 2006-11-27 | Ottawa Health Research Inst | Fremgangsmåder og produkter til induktion af mukosaimmunitet |
| US20040247662A1 (en) * | 1998-06-25 | 2004-12-09 | Dow Steven W. | Systemic immune activation method using nucleic acid-lipid complexes |
| GB9817052D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| ATE315405T1 (de) * | 1998-08-10 | 2006-02-15 | Antigenics Inc | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung |
| FR2783170B1 (fr) * | 1998-09-11 | 2004-07-16 | Pasteur Merieux Serums Vacc | Emulsion immunostimulante |
| DE60044236D1 (de) * | 1999-02-17 | 2010-06-02 | Csl Ltd | Immunogene komplexe und methoden in bezug auf diese |
| US6558670B1 (en) * | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
| ES2411096T3 (es) * | 1999-10-27 | 2013-07-04 | Novartis Vaccines And Diagnostics, Inc. | Activación de linfocitos T específicos contra el VHC |
| US6986892B1 (en) * | 1999-11-24 | 2006-01-17 | Chiron Corporation | Immunogenic Hepatitis C virus non-structural polypeptides |
| FR2814958B1 (fr) * | 2000-10-06 | 2003-03-07 | Aventis Pasteur | Composition vaccinale |
| US7713942B2 (en) * | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
| AU2002360278A1 (en) * | 2001-10-12 | 2003-11-11 | Coley Pharmaceutical Gmbh | Methods and products for enhancing immune responses using imidazoquinoline compounds |
| US20060210555A1 (en) * | 2001-12-21 | 2006-09-21 | Antigenics, Inc. | Compositions comprising immunoreactive reagents and saponins, and methods of use thereof |
| NZ535952A (en) * | 2002-04-04 | 2009-01-31 | Coley Pharm Gmbh | Immunostimulatory G,U-containing oligoribonucleotides |
| US7196892B2 (en) * | 2002-04-10 | 2007-03-27 | Caelin Gabriel | Method and apparatus for isolating RFI, EMI, and noise transients in power supply circuits |
| NZ540098A (en) * | 2002-10-29 | 2008-09-26 | Coley Pharmaceutical Group Ltd | Use of CPG oligonucleotides in the treatment of hepatitis C virus infection |
| JP5127224B2 (ja) * | 2003-06-17 | 2013-01-23 | マンカインド コーポレイション | 予防又は治療目的のためのmhcクラスi拘束性エピトープに対する免疫応答を誘発し、増強し、維持する方法 |
| US7410975B2 (en) * | 2003-06-20 | 2008-08-12 | Coley Pharmaceutical Group, Inc. | Small molecule toll-like receptor (TLR) antagonists |
| US20050013812A1 (en) * | 2003-07-14 | 2005-01-20 | Dow Steven W. | Vaccines using pattern recognition receptor-ligand:lipid complexes |
| JP4989225B2 (ja) * | 2003-09-25 | 2012-08-01 | コーリー ファーマシューティカル グループ,インコーポレイテッド | 核酸親油性接合体 |
| US20050215501A1 (en) * | 2003-10-24 | 2005-09-29 | Coley Pharmaceutical Group, Inc. | Methods and products for enhancing epitope spreading |
| EP1776105A2 (en) * | 2004-07-18 | 2007-04-25 | Coley Pharmaceutical Group, Ltd | Methods and compositions for inducing innate immune responses |
| JP2008506789A (ja) * | 2004-07-18 | 2008-03-06 | シーエスエル、リミテッド | インターフェロン−ガンマ応答強化を誘発するための免疫刺激複合体及びオリゴヌクレオチド処方物 |
| US20070190072A1 (en) * | 2004-09-30 | 2007-08-16 | Csl Limited Ludwig Institute For Cancer Research | In vivo efficacy of ny-eso-1 plus adjuvant |
| EP1874325A2 (en) * | 2005-04-08 | 2008-01-09 | Coley Pharmaceutical Group, Inc. | Methods for treating infectious disease exacerbated asthma |
| CN101522213A (zh) * | 2006-09-01 | 2009-09-02 | Csl有限公司 | 引起或诱导免疫应答的方法 |
-
2000
- 2000-11-17 DE DE60039715T patent/DE60039715D1/de not_active Expired - Lifetime
- 2000-11-17 WO PCT/AU2000/001410 patent/WO2001037869A1/en not_active Ceased
- 2000-11-17 EP EP00975681A patent/EP1239876B1/en not_active Expired - Lifetime
- 2000-11-17 HK HK03100096.0A patent/HK1047892B/en not_active IP Right Cessation
- 2000-11-17 AU AU13730/01A patent/AU772617B2/en not_active Ceased
- 2000-11-17 KR KR1020027006431A patent/KR100875483B1/ko not_active Expired - Fee Related
- 2000-11-17 NZ NZ518999A patent/NZ518999A/xx not_active IP Right Cessation
- 2000-11-17 ES ES00975681T patent/ES2311478T3/es not_active Expired - Lifetime
- 2000-11-17 CA CA2391843A patent/CA2391843C/en not_active Expired - Fee Related
- 2000-11-17 JP JP2001539483A patent/JP2003514872A/ja not_active Ceased
- 2000-11-17 AT AT00975681T patent/ATE402715T1/de not_active IP Right Cessation
- 2000-11-17 NZ NZ520976A patent/NZ520976A/en not_active IP Right Cessation
-
2003
- 2003-07-21 US US10/622,470 patent/US20040191270A1/en not_active Abandoned
-
2009
- 2009-11-05 US US12/612,992 patent/US20100047271A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08510240A (ja) * | 1993-05-12 | 1996-10-29 | カイロン コーポレイション | C型肝炎ウイルスe2/ns1領域の保存モチーフ |
| JPH09503396A (ja) * | 1994-07-29 | 1997-04-08 | インノジェネティクス・エヌ・ブイ | 診断用及び治療用の精製c型肝炎ウイルスエンベロープ蛋白 |
| JPH10508301A (ja) * | 1994-10-12 | 1998-08-18 | イスコテック、アクチボラグ | サポニン製剤およびiscomでのその使用 |
| JPH11508769A (ja) * | 1995-06-29 | 1999-08-03 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | C型肝炎に対するワクチン |
Non-Patent Citations (2)
| Title |
|---|
| JPN6010054972, Rimmelzwaan GF, et al., "A novel generation of viral vaccines based on the ISCOM matrix", Pharmaceutical Biotechnology, 1995, Vol. 6, p. 543−558 * |
| JPN6010054973, Barr IG, et al., "ISCOMs (immunostimulating complexes): The first decade", Immunology and Cell Biology, 1996, Vol. 74, No. 1, p. 8−25 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008511556A (ja) * | 2004-09-03 | 2008-04-17 | セントロ デ インジエニエリア ジエネテイカ イ バイオテクノロジア | C型肝炎ウイルスに対するワクチン組成物 |
| JP2014502959A (ja) * | 2010-11-26 | 2014-02-06 | ザ マクファーレーン バーネット インスティテュート フォー メディカル リサーチ アンド パブリック ヘルス リミテッド | 組成物および方法 |
| JP2014132030A (ja) * | 2014-04-08 | 2014-07-17 | Univ Of Melbourne:The | 免疫原性組成物およびその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR100875483B1 (ko) | 2008-12-22 |
| DE60039715D1 (de) | 2008-09-11 |
| CA2391843C (en) | 2011-10-18 |
| NZ520976A (en) | 2005-01-28 |
| US20100047271A1 (en) | 2010-02-25 |
| AU772617B2 (en) | 2004-05-06 |
| KR20020073338A (ko) | 2002-09-23 |
| US20040191270A1 (en) | 2004-09-30 |
| WO2001037869A1 (en) | 2001-05-31 |
| NZ518999A (en) | 2002-12-20 |
| AU1373001A (en) | 2001-06-04 |
| HK1047892B (en) | 2009-01-09 |
| HK1047892A1 (en) | 2003-03-14 |
| CA2391843A1 (en) | 2001-05-31 |
| WO2001037869A9 (en) | 2002-07-18 |
| ES2311478T3 (es) | 2009-02-16 |
| EP1239876B1 (en) | 2008-07-30 |
| EP1239876A1 (en) | 2002-09-18 |
| ATE402715T1 (de) | 2008-08-15 |
| EP1239876A4 (en) | 2003-05-02 |
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