KR100875483B1 - 백신 조성물 - Google Patents

백신 조성물 Download PDF

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Publication number
KR100875483B1
KR100875483B1 KR1020027006431A KR20027006431A KR100875483B1 KR 100875483 B1 KR100875483 B1 KR 100875483B1 KR 1020027006431 A KR1020027006431 A KR 1020027006431A KR 20027006431 A KR20027006431 A KR 20027006431A KR 100875483 B1 KR100875483 B1 KR 100875483B1
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KR
South Korea
Prior art keywords
hcv
delete delete
core
complex
immunogenic
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Expired - Fee Related
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KR1020027006431A
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English (en)
Korean (ko)
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KR20020073338A (ko
Inventor
드란데비에
콕스존
휴튼마이클
팔리아르드크사비에르
Original Assignee
씨에스엘 리미티드
노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드
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Publication of KR20020073338A publication Critical patent/KR20020073338A/ko
Application granted granted Critical
Publication of KR100875483B1 publication Critical patent/KR100875483B1/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020027006431A 1999-11-19 2000-11-17 백신 조성물 Expired - Fee Related KR100875483B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16665299P 1999-11-19 1999-11-19
US60/166,652 1999-11-19
US22436200P 2000-08-11 2000-08-11
US60/224,362 2000-08-11
PCT/AU2000/001410 WO2001037869A1 (en) 1999-11-19 2000-11-17 Vaccine compositions

Publications (2)

Publication Number Publication Date
KR20020073338A KR20020073338A (ko) 2002-09-23
KR100875483B1 true KR100875483B1 (ko) 2008-12-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027006431A Expired - Fee Related KR100875483B1 (ko) 1999-11-19 2000-11-17 백신 조성물

Country Status (12)

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US (2) US20040191270A1 (enExample)
EP (1) EP1239876B1 (enExample)
JP (1) JP2003514872A (enExample)
KR (1) KR100875483B1 (enExample)
AT (1) ATE402715T1 (enExample)
AU (1) AU772617B2 (enExample)
CA (1) CA2391843C (enExample)
DE (1) DE60039715D1 (enExample)
ES (1) ES2311478T3 (enExample)
HK (1) HK1047892B (enExample)
NZ (2) NZ520976A (enExample)
WO (1) WO2001037869A1 (enExample)

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WO2003055514A1 (en) * 2001-12-21 2003-07-10 Antigenics Inc. Compositions comprising immunoreactive reagents and saponins, and methods of use thereof
ATE458496T1 (de) * 2002-01-14 2010-03-15 Novartis Vaccines & Diagnostic Hiv-vakzine und anwendungsverfahren
WO2004060396A2 (en) 2002-12-27 2004-07-22 Chiron Corporation Immunogenic compositions containing phospholpid
EP1613647A2 (en) * 2003-04-11 2006-01-11 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Use of hcv proteins
EP1781325A2 (en) * 2004-07-18 2007-05-09 CSL Limited Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses
CU23496A1 (es) * 2004-09-03 2010-02-23 Ct Ingenieria Genetica Biotech Composición vacunal contra el virus de la hepatitis c
US20070190072A1 (en) * 2004-09-30 2007-08-16 Csl Limited Ludwig Institute For Cancer Research In vivo efficacy of ny-eso-1 plus adjuvant
CN102614510A (zh) * 2004-10-18 2012-08-01 全球免疫股份有限公司 基于酵母的对慢性丙型肝炎感染的治疗
ATE539079T1 (de) 2006-03-23 2012-01-15 Novartis Ag Imidazochinoxalinverbindungen als immunmodulatoren
CA2702154C (en) * 2007-10-09 2017-05-16 The University Of Melbourne A method of transfection and compositions therefor
WO2009046497A1 (en) * 2007-10-12 2009-04-16 Csl Limited Method of eliciting an immune response against pandemic influenza virus
US8728489B2 (en) 2008-09-19 2014-05-20 Globeimmune, Inc. Immunotherapy for chronic hepatitis C virus infection
JP2012523379A (ja) * 2009-04-09 2012-10-04 ザ ユニバーシティー オブ メルボルン 免疫原性組成物およびその使用
SG184804A1 (en) 2010-04-30 2012-11-29 Temasek Life Sciences Lab Ltd Universal vaccine against h5n1 lineages
ES2980738T3 (es) 2010-09-22 2024-10-02 Ena Respiratory Pty Ltd Composición para uso en un método inmunoestimulador
KR20140036127A (ko) * 2010-11-26 2014-03-25 더 맥파레인 버넷 인스티튜트 포 메디칼 리서치 앤드 퍼블릭 헬스 리미티드 조성물 및 방법
CU24112B1 (es) * 2012-11-05 2015-08-27 Ct De Ingeniería Genética Y Biotecnología Antígenos vacunales quiméricos contra el virus de la hepatitis c
JP5931113B2 (ja) * 2014-04-08 2016-06-08 ザ ユニバーシティー オブ メルボルン 免疫原性組成物およびその使用
CN106749672B (zh) * 2016-11-18 2020-06-30 江西农业大学 一种丙型肝炎病毒融合抗原蛋白及其应用
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Also Published As

Publication number Publication date
HK1047892B (en) 2009-01-09
EP1239876B1 (en) 2008-07-30
NZ520976A (en) 2005-01-28
EP1239876A1 (en) 2002-09-18
KR20020073338A (ko) 2002-09-23
JP2003514872A (ja) 2003-04-22
WO2001037869A9 (en) 2002-07-18
DE60039715D1 (de) 2008-09-11
US20100047271A1 (en) 2010-02-25
HK1047892A1 (en) 2003-03-14
EP1239876A4 (en) 2003-05-02
AU1373001A (en) 2001-06-04
NZ518999A (en) 2002-12-20
ATE402715T1 (de) 2008-08-15
US20040191270A1 (en) 2004-09-30
WO2001037869A1 (en) 2001-05-31
ES2311478T3 (es) 2009-02-16
CA2391843C (en) 2011-10-18
AU772617B2 (en) 2004-05-06
CA2391843A1 (en) 2001-05-31

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