JP2003511423A5 - - Google Patents

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Publication number
JP2003511423A5
JP2003511423A5 JP2001529754A JP2001529754A JP2003511423A5 JP 2003511423 A5 JP2003511423 A5 JP 2003511423A5 JP 2001529754 A JP2001529754 A JP 2001529754A JP 2001529754 A JP2001529754 A JP 2001529754A JP 2003511423 A5 JP2003511423 A5 JP 2003511423A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001529754A
Other languages
Japanese (ja)
Other versions
JP2003511423A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2000/028109 external-priority patent/WO2001026693A2/en
Publication of JP2003511423A publication Critical patent/JP2003511423A/ja
Publication of JP2003511423A5 publication Critical patent/JP2003511423A5/ja
Pending legal-status Critical Current

Links

JP2001529754A 1999-10-12 2000-10-12 ポリグルタメート−治療薬コンジュゲートの製造 Pending JP2003511423A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15913599P 1999-10-12 1999-10-12
US60/159,135 1999-10-12
PCT/US2000/028109 WO2001026693A2 (en) 1999-10-12 2000-10-12 Manufacture of polyglutamate-therapeutic agent conjugates

Publications (2)

Publication Number Publication Date
JP2003511423A JP2003511423A (ja) 2003-03-25
JP2003511423A5 true JP2003511423A5 (https=) 2005-12-08

Family

ID=22571222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001529754A Pending JP2003511423A (ja) 1999-10-12 2000-10-12 ポリグルタメート−治療薬コンジュゲートの製造

Country Status (16)

Country Link
US (2) US20020077279A1 (https=)
EP (2) EP1225917A2 (https=)
JP (1) JP2003511423A (https=)
KR (1) KR100821437B1 (https=)
CN (2) CN1607962A (https=)
AU (1) AU781735B2 (https=)
BR (1) BRPI0014652B1 (https=)
CA (1) CA2387611C (https=)
HU (1) HUP0203123A3 (https=)
MX (1) MXPA02003719A (https=)
NO (1) NO20021701L (https=)
NZ (1) NZ529789A (https=)
PL (1) PL354623A1 (https=)
SG (1) SG147286A1 (https=)
WO (1) WO2001026693A2 (https=)
ZA (1) ZA200202695B (https=)

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US8323669B2 (en) 2006-03-28 2012-12-04 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of taxane

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US7259156B2 (en) 2004-05-20 2007-08-21 Kosan Biosciences Incorporated Geldanamycin compounds and method of use
EP1877097B1 (en) 2004-08-11 2012-06-20 Arqule, Inc. Aminoacid conjugates of beta-lapachone for tumor targeting
US8614228B2 (en) 2004-08-11 2013-12-24 Arqule, Inc. Quinone prodrug compositions and methods of use
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CA2631704A1 (en) 2005-12-05 2007-06-14 Nitto Denko Corporation Polyglutamate-amino acid conjugates and methods
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US7671067B2 (en) * 2006-02-09 2010-03-02 Enzon Pharmaceuticals, Inc. Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin
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US8334364B2 (en) 2006-11-06 2012-12-18 Nipon Kayaku Kabushiki Kaisha High-molecular weight derivative of nucleic acid antimetabolite
JP5548365B2 (ja) 2006-11-08 2014-07-16 日本化薬株式会社 核酸系代謝拮抗剤の高分子誘導体
CN101209350B (zh) * 2006-12-30 2011-09-07 中国人民解放军军事医学科学院毒物药物研究所 以氨基酸为连接子的多聚谷氨酸-药物偶合物
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CN101674852A (zh) * 2007-04-10 2010-03-17 日东电工株式会社 多功能聚谷氨酸盐药物载体
ES2532656T3 (es) 2007-04-30 2015-03-30 Arqule, Inc. Compuestos de hidroxi sulfonato de quinona y sus usos
CA2683590A1 (en) * 2007-05-09 2008-11-20 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
CN101707869A (zh) * 2007-05-09 2010-05-12 日东电工株式会社 具有多种药物的聚谷氨酸盐结合物和聚谷氨酸盐-氨基酸结合物
JP2010528122A (ja) * 2007-05-09 2010-08-19 日東電工株式会社 白金薬剤と結合されたポリマー
JP5349318B2 (ja) 2007-09-28 2013-11-20 日本化薬株式会社 ステロイド類の高分子結合体
WO2009111271A1 (en) * 2008-03-06 2009-09-11 Nitto Denko Corporation Polymer paclitaxel conjugates and methods for treating cancer
CN101977631A (zh) 2008-03-18 2011-02-16 日本化药株式会社 生理活性物质的高分子量偶联物
JP5366940B2 (ja) 2008-05-08 2013-12-11 日本化薬株式会社 葉酸若しくは葉酸誘導体の高分子結合体
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KR20110075029A (ko) * 2008-10-21 2011-07-05 엔즌 파마슈티칼스, 인코포레이티드 7-에틸-10-하이드록시캄토테신의 다중-암 고분자 컨쥬게이트로 신경모세포종의 치료
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JP5544357B2 (ja) 2009-05-15 2014-07-09 日本化薬株式会社 水酸基を有する生理活性物質の高分子結合体
CA2777397C (en) 2009-10-13 2017-08-29 Rexahn Pharmaceuticals, Inc. Polymeric systems for the delivery of anticancer agents
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KR101507119B1 (ko) * 2013-05-31 2015-03-30 주식회사 바이오리더스 점막 점착성 폴리감마글루탐산 나노마이셀 및 이를 이용한 약물 전달체
CN106267227A (zh) * 2016-08-12 2017-01-04 北京蓝贝望生物医药科技股份有限公司 抗肿瘤药物
CN106750272B (zh) * 2016-12-05 2019-05-28 福建卫生职业技术学院 一种水溶性蛇葡萄素聚合物
CN110123748A (zh) * 2019-04-22 2019-08-16 南京师范大学 一种叶酸介导的靶向双载药聚合物胶束及其制备方法和应用
CN113773282A (zh) * 2021-09-22 2021-12-10 无锡紫杉药业有限公司 一种10-乙酰紫杉醇的制备方法

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US6441025B2 (en) * 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
HUP0204562A2 (hu) * 2000-03-17 2003-04-28 Cell Therapeutics, Inc. Poliglutaminsav-kamptotecin konjugátumok, eljárás előállításukra és ilyen konjugátumokat tartalmazó gyógyászati készítmények

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8323669B2 (en) 2006-03-28 2012-12-04 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of taxane

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