JP2003506048A5 - - Google Patents
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- Publication number
- JP2003506048A5 JP2003506048A5 JP2001514139A JP2001514139A JP2003506048A5 JP 2003506048 A5 JP2003506048 A5 JP 2003506048A5 JP 2001514139 A JP2001514139 A JP 2001514139A JP 2001514139 A JP2001514139 A JP 2001514139A JP 2003506048 A5 JP2003506048 A5 JP 2003506048A5
- Authority
- JP
- Japan
- Prior art keywords
- helicase
- archaeal
- seq
- amino acid
- rfc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108060004795 Methyltransferase Proteins 0.000 description 72
- 102000040430 polynucleotide Human genes 0.000 description 23
- 108091033319 polynucleotide Proteins 0.000 description 23
- 239000002157 polynucleotide Substances 0.000 description 23
- 125000003275 alpha amino acid group Chemical group 0.000 description 17
- 239000002773 nucleotide Substances 0.000 description 14
- 125000003729 nucleotide group Chemical group 0.000 description 14
- 102000039446 nucleic acids Human genes 0.000 description 12
- 108020004707 nucleic acids Proteins 0.000 description 12
- 150000007523 nucleic acids Chemical class 0.000 description 12
- 229920001184 polypeptide Polymers 0.000 description 10
- 108090000765 processed proteins & peptides Proteins 0.000 description 10
- 102000004196 processed proteins & peptides Human genes 0.000 description 10
- 108090000652 Flap endonucleases Proteins 0.000 description 9
- 102000004150 Flap endonucleases Human genes 0.000 description 9
- 101150088049 dna2 gene Proteins 0.000 description 9
- 108050006400 Cyclin Proteins 0.000 description 8
- 102000009339 Proliferating Cell Nuclear Antigen Human genes 0.000 description 8
- 230000001737 promoting effect Effects 0.000 description 8
- 102100027047 Cell division control protein 6 homolog Human genes 0.000 description 7
- 102100023933 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial Human genes 0.000 description 7
- 101000914465 Homo sapiens Cell division control protein 6 homolog Proteins 0.000 description 7
- 108090000364 Ligases Proteins 0.000 description 7
- 102000003960 Ligases Human genes 0.000 description 7
- 108010011219 dUTP pyrophosphatase Proteins 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 241000203069 Archaea Species 0.000 description 4
- 108010051862 Methylmalonyl-CoA mutase Proteins 0.000 description 3
- 102100030979 Methylmalonyl-CoA mutase, mitochondrial Human genes 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 108060002716 Exonuclease Proteins 0.000 description 2
- 102000013165 exonuclease Human genes 0.000 description 2
- 241000205156 Pyrococcus furiosus Species 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14658099P | 1999-07-30 | 1999-07-30 | |
| US60/146,580 | 1999-07-30 | ||
| PCT/US2000/020532 WO2001009347A2 (en) | 1999-07-30 | 2000-07-28 | Archaeal replication accessory factors and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003506048A JP2003506048A (ja) | 2003-02-18 |
| JP2003506048A5 true JP2003506048A5 (https=) | 2007-09-13 |
Family
ID=22518042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001514139A Withdrawn JP2003506048A (ja) | 1999-07-30 | 2000-07-28 | 古細菌複製補助因子及び使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7442766B2 (https=) |
| EP (1) | EP1208210A2 (https=) |
| JP (1) | JP2003506048A (https=) |
| AU (1) | AU6385800A (https=) |
| WO (1) | WO2001009347A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1007718B1 (en) | 1997-03-21 | 2007-11-14 | Stratagene California | Polymerase enhancing factor (pef) extracts, pef protein complexes, isolated pef protein, and methods for purifying and identifying |
| CN1183253C (zh) * | 1997-06-26 | 2005-01-05 | 宝生物工程株式会社 | Dna聚合酶相关因子 |
| US20030049614A1 (en) * | 1999-10-06 | 2003-03-13 | Holly Hurlbut Hogrefe | Compositions for dna amplification, synthesis, and mutagenesis |
| US20040009486A1 (en) | 1999-10-29 | 2004-01-15 | Sorge Joseph A. | Compositions and methods utilizing DNA polymerases |
| JP4473573B2 (ja) | 2001-07-26 | 2010-06-02 | ストラタジーン カリフォルニア | 多部位突然変異誘発 |
| ATE427992T1 (de) | 2001-11-14 | 2009-04-15 | Toyo Boseki | Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon |
| JP3762983B2 (ja) * | 2002-03-01 | 2006-04-05 | 独立行政法人産業技術総合研究所 | Ｄｎａヘリカーゼ |
| CA2498764C (en) * | 2002-09-20 | 2015-11-10 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
| AU2004225520A1 (en) | 2003-03-25 | 2004-10-14 | Stratagene | DNA polymerase fusions and uses thereof |
| CN101213295B (zh) | 2005-07-04 | 2011-12-14 | 赛利斯达雷克西克-赛恩斯株式会社 | 变异型pcna |
| JP5106416B2 (ja) | 2006-01-06 | 2012-12-26 | アジレント・テクノロジーズ・インク | 濃縮（ｐａｃｋｅｄ）ＤＮＡポリメラーゼを含む核酸複製のための反応緩衝液組成物 |
| JP4355830B2 (ja) * | 2006-05-15 | 2009-11-04 | 独立行政法人産業技術総合研究所 | 新規ｄｎａ複製因子 |
| US8685648B2 (en) | 2009-02-03 | 2014-04-01 | Biohelix Corporation | Endonuclease-enhanced helicase-dependent amplification |
| JP6332609B2 (ja) * | 2013-08-06 | 2018-05-30 | 東洋紡株式会社 | 変異型ｐｃｎａ |
| WO2016013620A1 (ja) * | 2014-07-24 | 2016-01-28 | 学校法人関西学院 | 好熱性アーキア由来ＤＥＡＤ－ｂｏｘ型ＲＮＡへリカーゼ及びその改変体を用いるＤＮＡ増幅方法、並びにその方法のために使用する好熱性アーキア由来ＤＥＡＤ－ｂｏｘ型ＲＮＡへリカーゼ及びその改変体 |
| JP6968536B2 (ja) * | 2014-11-28 | 2021-11-17 | 東洋紡株式会社 | 核酸増幅試薬 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5545552A (en) * | 1990-12-03 | 1996-08-13 | Stratagene | Purified thermostable pyrococcus furiosus DNA polymerase I |
| US5866395A (en) * | 1990-12-03 | 1999-02-02 | Stratagene | Purified thermostable pyrococcus furiosus DNA polymerase I |
| US5556772A (en) * | 1993-12-08 | 1996-09-17 | Stratagene | Polymerase compositions and uses thereof |
| JP3761197B2 (ja) * | 1995-12-27 | 2006-03-29 | タカラバイオ株式会社 | 新規ｄｎａポリメラーゼ |
| US6458556B1 (en) * | 1996-07-25 | 2002-10-01 | The Institute Of Physical & Chemical Research | Method for enhancing enzyme activity at elevated temperature |
| US6183997B1 (en) * | 1997-03-21 | 2001-02-06 | Stratagene | Polymerase enhancing factor (PEF) extracts PEF protein complexes isolated PEF proteins and methods for purifying and identifying same |
| EP1007718B1 (en) * | 1997-03-21 | 2007-11-14 | Stratagene California | Polymerase enhancing factor (pef) extracts, pef protein complexes, isolated pef protein, and methods for purifying and identifying |
| CN1183253C (zh) * | 1997-06-26 | 2005-01-05 | 宝生物工程株式会社 | Dna聚合酶相关因子 |
| US20030049614A1 (en) * | 1999-10-06 | 2003-03-13 | Holly Hurlbut Hogrefe | Compositions for dna amplification, synthesis, and mutagenesis |
-
2000
- 2000-07-28 JP JP2001514139A patent/JP2003506048A/ja not_active Withdrawn
- 2000-07-28 EP EP00950813A patent/EP1208210A2/en not_active Ceased
- 2000-07-28 AU AU63858/00A patent/AU6385800A/en not_active Abandoned
- 2000-07-28 WO PCT/US2000/020532 patent/WO2001009347A2/en not_active Ceased
-
2004
- 2004-04-20 US US10/828,924 patent/US7442766B2/en not_active Expired - Fee Related
-
2008
- 2008-10-24 US US12/258,288 patent/US20090221029A1/en not_active Abandoned
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