JP2003503361A5 - - Google Patents
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- Publication number
- JP2003503361A5 JP2003503361A5 JP2001505945A JP2001505945A JP2003503361A5 JP 2003503361 A5 JP2003503361 A5 JP 2003503361A5 JP 2001505945 A JP2001505945 A JP 2001505945A JP 2001505945 A JP2001505945 A JP 2001505945A JP 2003503361 A5 JP2003503361 A5 JP 2003503361A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- pharmaceutical composition
- prostate cancer
- use according
- monoclonal antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 15
- 206010060862 Prostate cancer Diseases 0.000 description 11
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 11
- 230000004913 activation Effects 0.000 description 7
- 102000008394 Immunoglobulin Fragments Human genes 0.000 description 6
- 108010021625 Immunoglobulin Fragments Proteins 0.000 description 6
- 239000002246 antineoplastic agent Substances 0.000 description 6
- 229940127089 cytotoxic agent Drugs 0.000 description 6
- 239000003145 cytotoxic factor Substances 0.000 description 6
- 239000003446 ligand Substances 0.000 description 5
- 102000043136 MAP kinase family Human genes 0.000 description 4
- 108091054455 MAP kinase family Proteins 0.000 description 4
- 229940123237 Taxane Drugs 0.000 description 3
- 239000003098 androgen Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 102000005962 receptors Human genes 0.000 description 3
- 108020003175 receptors Proteins 0.000 description 3
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 description 3
- 241000282412 Homo Species 0.000 description 2
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 description 2
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 description 2
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 description 2
- 101710100968 Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 description 2
- 102000006747 Transforming Growth Factor alpha Human genes 0.000 description 2
- 101800004564 Transforming growth factor alpha Proteins 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- -1 bind ErbB2 Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14131599P | 1999-06-25 | 1999-06-25 | |
| US60/141,315 | 1999-06-25 | ||
| PCT/US2000/017423 WO2001000238A1 (en) | 1999-06-25 | 2000-06-23 | TREATING PROSTATE CANCER WITH ANTI-ErbB2 ANTIBODIES |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009188783A Division JP2009269928A (ja) | 1999-06-25 | 2009-08-17 | 抗ＥｒｂＢ２抗体を用いる前立腺癌の処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003503361A JP2003503361A (ja) | 2003-01-28 |
| JP2003503361A5 true JP2003503361A5 (enExample) | 2006-01-19 |
| JP4579471B2 JP4579471B2 (ja) | 2010-11-10 |
Family
ID=22495163
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001505945A Expired - Fee Related JP4579471B2 (ja) | 1999-06-25 | 2000-06-23 | 抗ＥｒｂＢ２抗体を用いる前立腺癌の処置 |
| JP2009188783A Withdrawn JP2009269928A (ja) | 1999-06-25 | 2009-08-17 | 抗ＥｒｂＢ２抗体を用いる前立腺癌の処置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009188783A Withdrawn JP2009269928A (ja) | 1999-06-25 | 2009-08-17 | 抗ＥｒｂＢ２抗体を用いる前立腺癌の処置 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20060083739A1 (enExample) |
| EP (1) | EP1189634B1 (enExample) |
| JP (2) | JP4579471B2 (enExample) |
| KR (1) | KR100754049B1 (enExample) |
| CN (1) | CN100381172C (enExample) |
| AT (1) | ATE355079T1 (enExample) |
| AU (1) | AU779209B2 (enExample) |
| BR (1) | BR0012195A (enExample) |
| CA (1) | CA2383493C (enExample) |
| CY (1) | CY1107637T1 (enExample) |
| DE (1) | DE60033658T2 (enExample) |
| DK (1) | DK1189634T3 (enExample) |
| ES (1) | ES2282120T3 (enExample) |
| IL (1) | IL147017A0 (enExample) |
| MX (1) | MXPA01013395A (enExample) |
| PT (1) | PT1189634E (enExample) |
| WO (1) | WO2001000238A1 (enExample) |
| ZA (1) | ZA200110088B (enExample) |
Families Citing this family (73)
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| US20040013667A1 (en) * | 1999-06-25 | 2004-01-22 | Genentech, Inc. | Treatment with anti-ErbB2 antibodies |
| GEP20104998B (en) * | 1999-06-25 | 2010-06-10 | Genentech Inc | Humanized antibody which binds erbb2 and blocks activation by ligand receptor of erbb2 (variants) and use of the composition comprising these antibodies methods for treating cancer |
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| US6825333B1 (en) | 1999-08-20 | 2004-11-30 | Chiron Corporation | EGFH2 genes and gene products |
| EP1229934B1 (en) | 1999-10-01 | 2014-03-05 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| US7097840B2 (en) | 2000-03-16 | 2006-08-29 | Genentech, Inc. | Methods of treatment using anti-ErbB antibody-maytansinoid conjugates |
| IL152656A0 (en) | 2000-05-19 | 2003-06-24 | Genentech Inc | Gene detection assay for improving the likelihood of an effective response to an erbb antagonist cancer therapy |
| AU2003226065B2 (en) * | 2002-04-12 | 2009-02-26 | Ludwig Institute For Cancer Research, Ltd | Recombinant anti-interleukin-9 antibodies |
| US7198899B2 (en) * | 2002-06-03 | 2007-04-03 | Chiron Corporation | Use of NRG4, or inhibitors thereof, in the treatment of colon and pancreatic cancers |
| EP1803821B1 (en) * | 2002-06-05 | 2012-02-29 | Cedars-Sinai Medical Center | Methods for managing kinase inhibitor therapy |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| PT1698640E (pt) | 2003-10-01 | 2016-03-31 | Kyowa Hakko Kirin Co Ltd | Processo para estabilizar um anticorpo e composição sob a forma de solução estabilizada contendo o anticorpo |
| WO2005041981A1 (en) * | 2003-10-31 | 2005-05-12 | Kurume University | Combination therapy of peptide vaccination and estramustine treatment |
| JP4905624B2 (ja) * | 2003-10-31 | 2012-03-28 | 学校法人 久留米大学 | ペプチドワクチン投与およびエストラムスチン処置の併用療法 |
| JP4969440B2 (ja) * | 2004-04-08 | 2012-07-04 | デビッド， ビー． エイガス， | 疼痛治療のためのＥｒｂＢアンタゴニスト |
| SV2006002143A (es) * | 2004-06-16 | 2006-01-26 | Genentech Inc | Uso de un anticuerpo para el tratamiento del cancer resistente al platino |
| AU2005287404B2 (en) | 2004-07-22 | 2009-05-07 | Genentech, Inc. | HER2 antibody composition |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
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| MX2007008768A (es) | 2005-01-21 | 2007-10-19 | Genentech Inc | Dosificacion fija de anticuerpos her. |
| CN103251946A (zh) * | 2005-02-23 | 2013-08-21 | 健泰科生物技术公司 | 使用her二聚化抑制剂在癌症患者中延长病情进展前时间或存活 |
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| TW200812615A (en) | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 |
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| MY150756A (en) | 2006-08-21 | 2014-02-28 | Hoffmann La Roche | Tumor theraphy with an anti-vegf antibody |
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| US8557243B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | EFGR antibodies comprising modular recognition domains |
| US8557242B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | ERBB2 antibodies comprising modular recognition domains |
| US8574577B2 (en) | 2008-01-03 | 2013-11-05 | The Scripps Research Institute | VEGF antibodies comprising modular recognition domains |
| US8454960B2 (en) | 2008-01-03 | 2013-06-04 | The Scripps Research Institute | Multispecific antibody targeting and multivalency through modular recognition domains |
| GEP20156390B (en) | 2008-01-03 | 2015-11-10 | Scripps Research Inst | Antibody targeting through a modular recognition domain |
| TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物 |
| HUE025507T2 (en) | 2008-03-18 | 2016-02-29 | Genentech Inc | Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
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| SG10201507044PA (en) | 2009-05-29 | 2015-10-29 | Hoffmann La Roche | Modulators for her2 signaling in her2 expressing patients with gastric cancer |
| CA2784211C (en) | 2010-02-18 | 2019-12-24 | Genentech, Inc. | Neuregulin antagonists and use thereof in treating cancer |
| WO2011146568A1 (en) | 2010-05-19 | 2011-11-24 | Genentech, Inc. | Predicting response to a her inhibitor |
| EP2575880B1 (en) | 2010-05-27 | 2019-01-16 | Genmab A/S | Monoclonal antibodies against her2 epitope |
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| DK4403228T3 (da) | 2011-10-14 | 2025-10-13 | Hoffmann La Roche | Anvendelser for og fremstillet artikel indbefattende HER2-dimeriseringshæmmeren pertuzumab |
| US9327023B2 (en) | 2011-10-25 | 2016-05-03 | The Regents Of The University Of Michigan | HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells |
| SG11201402510TA (en) | 2011-11-30 | 2014-06-27 | Genentech Inc | Erbb3 mutations in cancer |
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| US20130195851A1 (en) | 2011-12-23 | 2013-08-01 | Genentech, Inc. | Articles of manufacture and methods for co-administration of antibodies |
| JP2015514710A (ja) | 2012-03-27 | 2015-05-21 | ジェネンテック， インコーポレイテッド | Ｈｅｒ３阻害剤に関する診断及び治療 |
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| RU2737727C2 (ru) | 2013-04-16 | 2020-12-02 | Дженентек, Инк. | Варианты пертузумаба и их аналитическая характеристика |
| RU2020120593A (ru) | 2014-04-25 | 2020-09-01 | Дженентек, Инк. | Способы лечения раннего рака молочной железы трастузумабом-mcc-dm1 и пертузумабом |
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| TW202508629A (zh) | 2017-01-17 | 2025-03-01 | 美商建南德克公司 | 皮下her2抗體調配物 |
| KR20230144110A (ko) | 2017-03-02 | 2023-10-13 | 제넨테크, 인크. | Her2-양성 유방암 어쥬번트 치료 |
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| US6358682B1 (en) * | 1998-01-26 | 2002-03-19 | Ventana Medical Systems, Inc. | Method and kit for the prognostication of breast cancer |
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-
2000
- 2000-06-23 CA CA2383493A patent/CA2383493C/en not_active Expired - Fee Related
- 2000-06-23 WO PCT/US2000/017423 patent/WO2001000238A1/en not_active Ceased
- 2000-06-23 ES ES00939992T patent/ES2282120T3/es not_active Expired - Lifetime
- 2000-06-23 AT AT00939992T patent/ATE355079T1/de active
- 2000-06-23 EP EP00939992A patent/EP1189634B1/en not_active Expired - Lifetime
- 2000-06-23 JP JP2001505945A patent/JP4579471B2/ja not_active Expired - Fee Related
- 2000-06-23 CN CNB008108668A patent/CN100381172C/zh not_active Expired - Fee Related
- 2000-06-23 AU AU54992/00A patent/AU779209B2/en not_active Ceased
- 2000-06-23 KR KR1020017016538A patent/KR100754049B1/ko not_active Expired - Fee Related
- 2000-06-23 DK DK00939992T patent/DK1189634T3/da active
- 2000-06-23 MX MXPA01013395A patent/MXPA01013395A/es active IP Right Grant
- 2000-06-23 PT PT00939992T patent/PT1189634E/pt unknown
- 2000-06-23 IL IL14701700A patent/IL147017A0/xx not_active IP Right Cessation
- 2000-06-23 DE DE60033658T patent/DE60033658T2/de not_active Expired - Lifetime
- 2000-06-23 BR BR0012195-9A patent/BR0012195A/pt active Search and Examination
-
2001
- 2001-12-07 ZA ZA200110088A patent/ZA200110088B/en unknown
-
2005
- 2005-09-23 US US11/234,586 patent/US20060083739A1/en not_active Abandoned
-
2007
- 2007-05-23 CY CY20071100697T patent/CY1107637T1/el unknown
-
2008
- 2008-10-08 US US12/247,850 patent/US20090087432A1/en not_active Abandoned
-
2009
- 2009-08-17 JP JP2009188783A patent/JP2009269928A/ja not_active Withdrawn
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