JP2003334088A - ヒト由来の新規Klotho様タンパク質及びその遺伝子 - Google Patents
ヒト由来の新規Klotho様タンパク質及びその遺伝子Info
- Publication number
- JP2003334088A JP2003334088A JP2002148341A JP2002148341A JP2003334088A JP 2003334088 A JP2003334088 A JP 2003334088A JP 2002148341 A JP2002148341 A JP 2002148341A JP 2002148341 A JP2002148341 A JP 2002148341A JP 2003334088 A JP2003334088 A JP 2003334088A
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- JP
- Japan
- Prior art keywords
- leu
- ala
- ser
- gly
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2006158339A (ja) * | 2004-12-09 | 2006-06-22 | Kyoto Univ | βKlotho遺伝子、Cyp7a1遺伝子、及びそれらの利用 |
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EP2550972A1 (en) * | 2007-04-02 | 2013-01-30 | Genentech, Inc. | Klotho-beta for use in treating cancer, liver disorders, gallstones, wasting syndrome and obesity-related diseases |
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US10246518B2 (en) | 2013-12-23 | 2019-04-02 | Genentech, Inc. | Nucleic acids encoding bispecific antibodies binding to beta-Klotho and fibroblast growth factor receptor 1 |
US10882921B2 (en) | 2013-12-23 | 2021-01-05 | Genentech, Inc. | Host cell comprising nucleic acids encoding bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1 and antibody production |
US9873748B2 (en) | 2013-12-23 | 2018-01-23 | Genentech, Inc. | Bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1 |
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US11667708B2 (en) | 2015-07-29 | 2023-06-06 | Ngm Biopharmaceuticals, Inc. | Anti-human beta klotho antibody or binding fragment thereof and methods of their use |
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