JP2002542162A5 - - Google Patents

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Publication number
JP2002542162A5
JP2002542162A5 JP2000611546A JP2000611546A JP2002542162A5 JP 2002542162 A5 JP2002542162 A5 JP 2002542162A5 JP 2000611546 A JP2000611546 A JP 2000611546A JP 2000611546 A JP2000611546 A JP 2000611546A JP 2002542162 A5 JP2002542162 A5 JP 2002542162A5
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JP
Japan
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acid
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compound
integer
group
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000611546A
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English (en)
Japanese (ja)
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JP2002542162A (ja
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Priority claimed from IT1999MI000751A external-priority patent/IT1311922B1/it
Application filed filed Critical
Publication of JP2002542162A publication Critical patent/JP2002542162A/ja
Publication of JP2002542162A5 publication Critical patent/JP2002542162A5/ja
Pending legal-status Critical Current

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JP2000611546A 1999-04-13 2000-04-11 医薬化合物 Pending JP2002542162A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT99A000751 1999-04-13
IT1999MI000751A IT1311922B1 (it) 1999-04-13 1999-04-13 Composti farmaceutici.
PCT/EP2000/003238 WO2000061604A2 (en) 1999-04-13 2000-04-11 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
JP2002542162A JP2002542162A (ja) 2002-12-10
JP2002542162A5 true JP2002542162A5 (https=) 2007-05-10

Family

ID=11382683

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000611546A Pending JP2002542162A (ja) 1999-04-13 2000-04-11 医薬化合物

Country Status (25)

Country Link
US (3) US6909007B1 (https=)
EP (2) EP1475386A3 (https=)
JP (1) JP2002542162A (https=)
KR (2) KR100744701B1 (https=)
CN (2) CN1296380C (https=)
AT (1) ATE274521T1 (https=)
AU (2) AU766798B2 (https=)
BR (1) BR0009696A (https=)
CA (2) CA2370446C (https=)
DE (1) DE60013266T2 (https=)
DK (1) DK1169337T3 (https=)
ES (1) ES2226805T3 (https=)
HU (1) HUP0201872A3 (https=)
IL (2) IL145633A0 (https=)
IT (1) IT1311922B1 (https=)
MX (1) MXPA01010212A (https=)
NO (2) NO323374B1 (https=)
NZ (1) NZ514572A (https=)
PL (1) PL199579B1 (https=)
PT (1) PT1169337E (https=)
RU (1) RU2240325C2 (https=)
SI (1) SI1169337T1 (https=)
TR (2) TR200201899T2 (https=)
WO (1) WO2000061604A2 (https=)
ZA (1) ZA200108124B (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2393724A1 (en) 1999-12-23 2001-06-28 Nitromed, Inc. Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
JP4092203B2 (ja) 2000-12-21 2008-05-28 ニトロメッド,インク. 新規のシクロオキシゲナーゼ2選択的阻害剤としての置換アリール化合物、組成物、および使用方法
IT1320176B1 (it) * 2000-12-22 2003-11-26 Nicox Sa Dispersioni solide di principi attivi nitrati.
EP1219306A1 (en) 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
US6696592B2 (en) 2001-05-22 2004-02-24 Nicox-S.A. Methods of making 21-[4′-(nitrooxyalkyl)benzoate] corticosteroid derivatives and intermediates useful in the synthesis thereof
ITMI20011307A1 (it) * 2001-06-21 2002-12-21 Nicox Sa Farmaci per l'epilessia
ITMI20020148A1 (it) 2002-01-29 2003-07-29 Nicox Sa Nuovi corticosteroidi
ITMI20021025A1 (it) * 2002-05-14 2003-11-14 Nicox Sa Farmaci per il trattamento acuto di disfunzioni del circolo venoso epatico e portale
WO2003103602A2 (en) 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
AU2003279622A1 (en) 2002-06-28 2004-01-19 Nitromed, Inc. Oxime and/or hydrazone containing nitrosated and/or nitrosylated cyclooxigenase-2 selective inhibitors, compositions and methods of use
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
AU2003261281A1 (en) 2002-07-29 2004-02-16 Nicox S.A. Cyclooxygenase- 2 selective inhibitors, compositions and methods of use
CN100513415C (zh) * 2005-08-03 2009-07-15 中国人民解放军军事医学科学院毒物药物研究所 胆汁酸衍生物及其医药用途
EP1940863B1 (en) 2005-09-02 2012-09-05 Nicox S.A. Nitrooxy derivatives of glucocorticoids
US8802726B2 (en) 2006-02-03 2014-08-12 Nicox S.A. Use of nitrooxyderivative of drug for the treatment of muscular dystrophies
US7645749B2 (en) 2006-04-03 2010-01-12 Forbes Medi-Tech Inc. Sterol/stanol nitroderivatives and use thereof
US7645748B2 (en) 2006-04-03 2010-01-12 Forbes Medi-Tech Inc. Sterol/stanol phosphorylnitroderivatives and use thereof
BRPI0807078A2 (pt) * 2007-02-05 2014-04-08 Nicox Sa Composto, e, formulação farmacêutica
US20090087425A1 (en) * 2007-08-10 2009-04-02 Topigen Pharmaceuticals Inc. Combination of nitroderivatized steroid and bronchodilator for treating respiratory disease
US20090088411A1 (en) * 2007-08-31 2009-04-02 Topigen Pharmaceuticals Inc. No-donating corticosteroid with improved pharmacokinetic, anti-inflammatory and vasodilatory properties
EP2214674A4 (en) * 2007-10-19 2011-03-30 Burnham Inst Medical Research INHIBITORS OF ANTI-APOPTOTIC PROTEINS
CN102186873A (zh) 2008-08-05 2011-09-14 尼科克斯公司 用于治疗视网膜和黄斑疾病的新型释放no的甾类化合物
EP2560634A1 (en) 2010-04-23 2013-02-27 Piramal Enterprises Limited Nitric oxide releasing prodrugs of therapeutic agents
CU20110244A7 (es) 2011-12-27 2013-08-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios
CA2897571C (en) 2013-01-21 2018-12-18 Apparao Satyam Nitric oxide releasing prodrugs of therapeutic agents containing at least one carboxylic acid group
KR101711513B1 (ko) * 2015-06-26 2017-03-02 주식회사 엘지생활건강 피부 개선용 조성물

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2077750B1 (https=) 1970-02-11 1973-03-16 Clin Byla Ets
GB1458372A (en) 1973-03-05 1976-12-15 Leo Ab Steroid carbamates and allophanates
JPS5845724A (ja) 1981-09-11 1983-03-17 Oriza Yuka Kk オリザノ−ル乳化液の製造法
FR2600653B1 (fr) * 1986-06-24 1988-12-16 Pasteur Strasbourg Universite Composes de synthese associative d'acides amines soufres ou non soufres avec des derives du d-4 pregnene 3,20-dione ou avec des derives du d-1,4 pregnadiene 3,20-dione aux proprietes glucocorticoides et anti-inflammatoires, procedes d'obtention, compositions pharmaceutiques les contenant. proprietes pharmacologiques et applications
IT1204571B (it) * 1987-05-08 1989-03-10 Chiesi Farma Spa Esteri di 1,4:3,6-dianidrosorbitolo-2-mononitrato e 5-mononitrato,loro procedimento di preparazione e loro composizioni farmaceutiche
DE3856512T2 (de) * 1987-06-29 2002-08-08 Massachusetts Institute Of Technology, Cambridge Nucleotidsequenz für Acetoacetyl-CoA Reduktase kodierend und Verfahren zur Herstellung von Polyester-Biopolymeren
DE4000397A1 (de) 1990-01-09 1991-07-11 Hoechst Ag Lipidselektive antioxidantien sowie deren herstellung und verwendung
JPH04273892A (ja) 1991-02-27 1992-09-30 Kao Corp 新規な21−置換ステロイド化合物
JP3108474B2 (ja) 1991-08-07 2000-11-13 日清製粉株式会社 活性型ビタミンd誘導体
IL104201A0 (en) 1991-12-26 1993-05-13 Wisconsin Alumni Res Found 26,27-dimethylene-1 alpha-25-dihydroxyvitamin d2 and its 24-epimer and pharmaceutical compositions containing them
EP0562497A1 (en) 1992-03-27 1993-09-29 Nisshin Flour Milling Co., Ltd. 1 alpha-hydroxy vitamins D7 and D4' processes for the preparation thereof and pharmaceutical compositions
US5194431A (en) 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
US5707984A (en) 1995-12-08 1998-01-13 G. D. Searle & Co. Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs
US5837698A (en) * 1996-05-02 1998-11-17 G. D. Searle & Co. Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs
US5985862A (en) * 1996-05-02 1999-11-16 G.D. Searle & Co. Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs
DE19634793A1 (de) 1996-08-29 1998-03-05 Sanol Arznei Schwarz Gmbh S- und O-Nitratoacylverbindungen
IT1285770B1 (it) * 1996-10-04 1998-06-18 Nicox Sa Composti corticoidei

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