JP2002534399A5 - - Google Patents

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Publication number
JP2002534399A5
JP2002534399A5 JP2000592029A JP2000592029A JP2002534399A5 JP 2002534399 A5 JP2002534399 A5 JP 2002534399A5 JP 2000592029 A JP2000592029 A JP 2000592029A JP 2000592029 A JP2000592029 A JP 2000592029A JP 2002534399 A5 JP2002534399 A5 JP 2002534399A5
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JP
Japan
Prior art keywords
acid
liquid
bone
formulation
combination
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JP2000592029A
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English (en)
Japanese (ja)
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JP4649044B2 (ja
JP2002534399A (ja
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Priority claimed from NO990001A external-priority patent/NO310544B1/no
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Publication of JP2002534399A publication Critical patent/JP2002534399A/ja
Publication of JP2002534399A5 publication Critical patent/JP2002534399A5/ja
Application granted granted Critical
Publication of JP4649044B2 publication Critical patent/JP4649044B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2000592029A 1999-01-04 1999-12-17 ラジウム−２２３の製造方法及びラジウム−２２３を含むキット Expired - Lifetime JP4649044B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO990001A NO310544B1 (no) 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO19990001 1999-01-04
PCT/NO1999/000392 WO2000040275A2 (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010096736A Division JP5433490B2 (ja) 1999-01-04 2010-04-20 石灰化組織を標的とする痛みの緩和、骨癌の治療および骨表面の調節のためのラジウム−２２３の製剤および使用

Publications (3)

Publication Number Publication Date
JP2002534399A JP2002534399A (ja) 2002-10-15
JP2002534399A5 true JP2002534399A5 (enExample) 2006-09-28
JP4649044B2 JP4649044B2 (ja) 2011-03-09

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ID=19902803

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000592029A Expired - Lifetime JP4649044B2 (ja) 1999-01-04 1999-12-17 ラジウム−２２３の製造方法及びラジウム−２２３を含むキット
JP2010096736A Expired - Lifetime JP5433490B2 (ja) 1999-01-04 2010-04-20 石灰化組織を標的とする痛みの緩和、骨癌の治療および骨表面の調節のためのラジウム−２２３の製剤および使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010096736A Expired - Lifetime JP5433490B2 (ja) 1999-01-04 2010-04-20 石灰化組織を標的とする痛みの緩和、骨癌の治療および骨表面の調節のためのラジウム−２２３の製剤および使用

Country Status (24)

Country Link
US (2) US6635234B1 (enExample)
EP (1) EP1140212B1 (enExample)
JP (2) JP4649044B2 (enExample)
KR (1) KR100671387B1 (enExample)
CN (2) CN1767078B (enExample)
AT (1) ATE331534T1 (enExample)
AU (1) AU774991B2 (enExample)
BE (1) BE2014C028I2 (enExample)
BR (1) BR9916768A (enExample)
CA (1) CA2358498C (enExample)
CY (2) CY1105634T1 (enExample)
DE (1) DE69932183T2 (enExample)
DK (1) DK1140212T3 (enExample)
EA (1) EA003496B1 (enExample)
ES (1) ES2268888T3 (enExample)
IL (1) IL144135A0 (enExample)
LU (1) LU92425I2 (enExample)
MX (1) MXPA01006823A (enExample)
NO (2) NO310544B1 (enExample)
NZ (3) NZ545023A (enExample)
PT (1) PT1140212E (enExample)
TR (3) TR200201440T2 (enExample)
WO (1) WO2000040275A2 (enExample)
ZA (1) ZA200105431B (enExample)

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NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO313180B1 (no) 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
AUPQ923100A0 (en) * 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
EP1469860A4 (en) * 2002-01-24 2005-09-07 Yissum Res Dev Co ANTICANCER COMBINATION AND USE THEREOF
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
CA2523646C (en) * 2003-04-30 2012-07-03 Ramot At Tel Aviv University Ltd. Method and device for radiotherapy
BRPI0507824A (pt) * 2004-02-20 2007-07-10 Algeta As hidroxiapatita, processo para a preparação de um particulado de hidroxiapatita marcada com radionuclìdeo, composição farmacêutica, uso de hidroxiapatita e de um radionuclìdeo emissor de alfa ou um radionuclìdeo emissor de beta, dispositivo, e, método de tratamento radioquìmico de um ser humano ou de um indivìduo animal não humano necessitando do mesmo
DE102004022200B4 (de) * 2004-05-05 2006-07-20 Actinium Pharmaceuticals, Inc. Radium-Target sowie Verfahren zu seiner Herstellung
US7914766B1 (en) * 2004-06-03 2011-03-29 Ut-Battelle Llc Inorganic resins for clinical use of 213Bi generators
GB0423565D0 (en) * 2004-10-22 2004-11-24 Algeta As Formulation
PL1909855T3 (pl) * 2005-07-26 2018-09-28 Aplha Tau Medical Ltd. Promieniotwórcze źródło powierzchniowe i sposób jego wytwarzania
US8709380B1 (en) * 2006-02-07 2014-04-29 Sirius Medicine, Llc Targeting agents for enhancing radiation therapy
DE102006008023B4 (de) * 2006-02-21 2008-05-29 Actinium Pharmaceuticals, Inc. Verfahren zum Reinigen von 225Ac aus bestrahlten 226Ra-Targets
ES2784662T3 (es) 2006-09-08 2020-09-29 Actinium Pharmaceuticals Inc Método para la purificación de radio a partir de diferentes fuentes
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
EP2353598A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for use in the prevention and/or treatment of postoperative pain
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201007354D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
GB201007353D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
CA2895356A1 (en) 2012-12-19 2014-06-26 Bayer Pharma Aktiengesellschaft Combination comprising radium-223 for the treatment of cancer
GB201314718D0 (en) * 2013-08-16 2013-10-02 Algeta As Quantification method
WO2015082322A1 (en) 2013-12-03 2015-06-11 Bayer Pharma Aktiengesellschaft COMBINATION of PI3K-INHIBITORS
US10124007B2 (en) 2013-12-03 2018-11-13 Bayer Pharma Aktiengesellschaft Combination of PI3K-inhibitors
AU2014364647A1 (en) 2013-12-17 2016-06-23 Laboratorios Del Dr. Esteve, S.A. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Sigma receptor ligands combinations
WO2016083739A1 (fr) 2014-11-26 2016-06-02 Rhodia Operations Composition de lanthane et d'actinium-227
GB201600154D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
GB201600153D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
CZ307369B6 (cs) * 2016-12-22 2018-07-04 České vysoké učení technické v Praze Kombinace pro radionuklidovou terapii pro použití jako léčivo
UY37616A (es) 2017-02-24 2018-09-28 Bayer Ag Combinación de inhibidores de quinasa atr con sal de radio-223
SG11201910176PA (en) 2017-05-11 2019-11-28 Alpha Tau Medical Ltd Polymer coatings for brachytherapy devices
CN111918699B (zh) 2018-04-02 2024-03-08 阿尔法陶医疗有限公司 放射性核素的受控释放的装置
EP3563875A1 (en) * 2018-05-04 2019-11-06 Ceské vysoké ucení technické v Praze Radium for radionuclide therapy, in combination with calcium metabolism affecting treatment
LU100900B1 (de) * 2018-08-10 2020-02-17 Thomas Melchior Homann Verbindungen zur modulation von a-ketoglutarsäure (2kg)-abhängigen oxygenasen
FR3086186B1 (fr) * 2018-09-26 2022-01-28 Orano Med Procede de production de plomb-212 a partir d'une solution aqueuse comprenant du thorium-228 et ses descendants
FR3088769B1 (fr) * 2018-11-15 2020-12-25 Orano Med Procede de preparation d'au moins un generateur a haute teneur en radium-228
US20220152228A1 (en) * 2019-03-01 2022-05-19 Washington University Compositions and methods for radiotherapy using chelated radiotherapeutic agents and non-target tissue blockade
MX2022006638A (es) 2019-12-05 2022-07-19 Sciencons AS Producción de 212pb altamente purificados.
RU2752845C1 (ru) * 2020-05-13 2021-08-11 Акционерное Общество "Наука И Инновации" Способ получения высокочистого радия-223
CA3202211A1 (en) * 2020-12-16 2022-06-23 Alpha Tau Medical Ltd. Diffusing alpha-emitters radiation therapy with enhanced beta treatment
CN113066598B (zh) * 2021-03-25 2023-08-08 中国科学院近代物理研究所 一种从高能质子束辐照232Th靶引起的散裂反应中分离纯化223Ra的方法
US12070620B2 (en) 2021-06-10 2024-08-27 Alpha Tau Medical Ltd. Activity levels for diffusing alpha-emitter radiation therapy
US12076582B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for colorectal cancer
US12064643B2 (en) 2021-06-10 2024-08-20 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for breast cancer
US12070621B2 (en) 2021-06-10 2024-08-27 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for pancreatic cancer
US12042668B2 (en) 2021-06-10 2024-07-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for squamous cell carcinoma
US11964168B2 (en) 2021-06-10 2024-04-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for prostate cancer
US12076583B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for melanoma
US12076581B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for glioblastoma
JP2025507614A (ja) 2022-02-21 2025-03-21 バイエル・ヘルスケア・エルエルシー 治療薬または診断薬の送達のためのシステム、方法、およびデバイス
IL314841A (en) 2022-02-21 2024-10-01 Bayer Healthcare Llc A system, method and device for administering a therapeutic or diagnostic substance
CN115869658B (zh) * 2022-12-29 2025-01-28 中国核动力研究设计院 用于制备Ra-223的分离系统及其分离方法、应用和制备方法

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NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
US20060228297A1 (en) * 2003-04-15 2006-10-12 Roy Larsen Thorium-227 for use in radiotherapy of soft tissue disease
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy

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