BE2014C028I2 - - Google Patents

Info

Publication number
BE2014C028I2
BE2014C028I2 BE2014C028C BE2014C028C BE2014C028I2 BE 2014C028 I2 BE2014C028 I2 BE 2014C028I2 BE 2014C028 C BE2014C028 C BE 2014C028C BE 2014C028 C BE2014C028 C BE 2014C028C BE 2014C028 I2 BE2014C028 I2 BE 2014C028I2
Authority
BE
Belgium
Prior art keywords
treatment
tumors
bone
radium
bones
Prior art date
Application number
BE2014C028C
Other languages
English (en)
Original Assignee
Bayer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer As filed Critical Bayer As
Publication of BE2014C028I2 publication Critical patent/BE2014C028I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Compounds Of Unknown Constitution (AREA)
BE2014C028C 1999-01-04 2014-05-07 BE2014C028I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO990001A NO310544B1 (no) 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
PCT/NO1999/000392 WO2000040275A2 (fr) 1999-01-04 1999-12-17 Preparation et utilisation du radium 223 pour cibler des tissus calcifies a des fins de traitement palliatif contre la douleur, de traitement du cancer des os et de conditionnement de surfaces osseuses

Publications (1)

Publication Number Publication Date
BE2014C028I2 true BE2014C028I2 (fr) 2019-03-05

Family

ID=19902803

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2014C028C BE2014C028I2 (fr) 1999-01-04 2014-05-07

Country Status (25)

Country Link
US (2) US6635234B1 (fr)
EP (1) EP1140212B1 (fr)
JP (2) JP4649044B2 (fr)
KR (1) KR100671387B1 (fr)
CN (2) CN1767078B (fr)
AT (1) ATE331534T1 (fr)
AU (1) AU774991B2 (fr)
BE (1) BE2014C028I2 (fr)
BR (1) BR9916768A (fr)
CA (1) CA2358498C (fr)
CY (2) CY1105634T1 (fr)
DE (1) DE69932183T2 (fr)
DK (1) DK1140212T3 (fr)
EA (1) EA003496B1 (fr)
ES (1) ES2268888T3 (fr)
HK (1) HK1090750A1 (fr)
IL (1) IL144135A0 (fr)
LU (1) LU92425I2 (fr)
MX (1) MXPA01006823A (fr)
NO (2) NO310544B1 (fr)
NZ (3) NZ534618A (fr)
PT (1) PT1140212E (fr)
TR (3) TR200201442T2 (fr)
WO (1) WO2000040275A2 (fr)
ZA (1) ZA200105431B (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
AUPQ923100A0 (en) * 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
WO2003061566A2 (fr) * 2002-01-24 2003-07-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Combinaison anticancereuse et son utilisation
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
EP2060274B1 (fr) 2003-04-30 2014-03-26 Ramot at Tel-Aviv University Ltd. Procédé et dispositif de radiothérapie
PL1735013T3 (pl) * 2004-02-20 2012-07-31 Algeta Asa Cząstki hydroksyapatytu alfa- i beta-emitujące
DE102004022200B4 (de) * 2004-05-05 2006-07-20 Actinium Pharmaceuticals, Inc. Radium-Target sowie Verfahren zu seiner Herstellung
US7914766B1 (en) * 2004-06-03 2011-03-29 Ut-Battelle Llc Inorganic resins for clinical use of 213Bi generators
GB0423565D0 (en) * 2004-10-22 2004-11-24 Algeta As Formulation
SI1909855T1 (en) * 2005-07-26 2018-06-29 Alpha Tau Medical Ltd. A radioactive surface source and a process for producing it
US8709380B1 (en) * 2006-02-07 2014-04-29 Sirius Medicine, Llc Targeting agents for enhancing radiation therapy
DE102006008023B4 (de) * 2006-02-21 2008-05-29 Actinium Pharmaceuticals, Inc. Verfahren zum Reinigen von 225Ac aus bestrahlten 226Ra-Targets
CA2950532C (fr) 2006-09-08 2018-10-23 Actinium Pharmaceuticals, Inc. Procede pour la purification du radium de differentes sources
EP2116539A1 (fr) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles en tant que ligands améliorant les effets analgésiques des opioïdes et réduisant leur dépendance
EP2353591A1 (fr) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Ligands sigma pour la potentialisation de l'effet analgésique d'opioïdes et d'opiacés dans la douleur post-opératoire et en atténuant la dépendance
EP2353598A1 (fr) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Ligands sigma pour utilisation dans la prévention et/ou le traitement de la douleur post-opératoire
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201007353D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
GB201007354D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
EP2388005A1 (fr) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Ligands sigma pour la prévention et/ou le traitement du vomissement induit par la chimiothérapie ou la radiothérapie
EP2415471A1 (fr) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Utilisation de ligands sigma dans l'hyperalgie induite par opioïdes
EP2524694A1 (fr) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Utilisation de ligands sigma dans la douleur liée au diabète de type 2
EP2934545A1 (fr) 2012-12-19 2015-10-28 Bayer Pharma Aktiengesellschaft Combinaison comprenant du radium-223 pour le traitement du cancer
GB201314718D0 (en) * 2013-08-16 2013-10-02 Algeta As Quantification method
EP3077003A1 (fr) 2013-12-03 2016-10-12 Bayer Pharma Aktiengesellschaft Combinaison d'inhibiteurs de la pi3k
EP3077002B1 (fr) 2013-12-03 2020-04-22 Bayer Pharma Aktiengesellschaft Combinaisons d'inhibiteurs de pi3k
AU2014364647A1 (en) 2013-12-17 2016-06-23 Laboratorios Del Dr. Esteve, S.A. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Sigma receptor ligands combinations
WO2016083739A1 (fr) 2014-11-26 2016-06-02 Rhodia Operations Composition de lanthane et d'actinium-227
GB201600154D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
GB201600153D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
CZ307369B6 (cs) * 2016-12-22 2018-07-04 České vysoké učení technické v Praze Kombinace pro radionuklidovou terapii pro použití jako léčivo
AR110995A1 (es) 2017-02-24 2019-05-22 Bayer Ag Combinación de inhibidores de quinasa atr con sal de radio-223
MX2019013346A (es) 2017-05-11 2020-01-20 Alpha Tau Medical Ltd Recubrimientos polimericos para dispositivos de braquiterapia.
RU2020130217A (ru) 2018-04-02 2022-05-04 Альфа Тау Медикал Лтд. Контролируемое высвобождение радионуклидов
EP3563875A1 (fr) * 2018-05-04 2019-11-06 Ceské vysoké ucení technické v Praze Le radium pour utilisation dans la thérapie aux radionuclides, en combinaison avec une thérapie qui influence le métabolisme du calcium
FR3086186B1 (fr) * 2018-09-26 2022-01-28 Orano Med Procede de production de plomb-212 a partir d'une solution aqueuse comprenant du thorium-228 et ses descendants
FR3088769B1 (fr) * 2018-11-15 2020-12-25 Orano Med Procede de preparation d'au moins un generateur a haute teneur en radium-228
WO2020180756A1 (fr) * 2019-03-01 2020-09-10 Washington University Compositions et méthodes de radiothérapie utilisant des agents radio-thérapeutiques chélatés et leur blocage au niveau des tissus non ciblés
RU2752845C1 (ru) * 2020-05-13 2021-08-11 Акционерное Общество "Наука И Инновации" Способ получения высокочистого радия-223
IL303002A (en) * 2020-12-16 2023-07-01 Alpha Tau Medical Ltd Radiotherapy by diffuse alpha emitters with increased beta therapy
CN113066598B (zh) * 2021-03-25 2023-08-08 中国科学院近代物理研究所 一种从高能质子束辐照232Th靶引起的散裂反应中分离纯化223Ra的方法
US11964168B2 (en) 2021-06-10 2024-04-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for prostate cancer
WO2023159229A1 (fr) 2022-02-21 2023-08-24 Bayer Healthcare Llc Système, procédé et dispositif d'administration d'un agent thérapeutique ou de diagnostic
WO2023159230A1 (fr) 2022-02-21 2023-08-24 Bayer Healthcare Llc Système, procédé et dispositif pour l'administration d'un agent thérapeutique ou diagnostique

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH668489A5 (de) * 1982-01-22 1988-12-30 Vnii Mineralnogo Syrya Radiometrisches verfahren zur bestimmung der konzentration natuerlicher radiumisotope und einrichtung zur durchfuehrung des verfahrens.
JPH04501265A (ja) * 1988-10-14 1992-03-05 マリンクロッド・インコーポレイテッド ラジオ標識粒状組成物
US4970062A (en) * 1989-05-30 1990-11-13 The United States Of America As Represented By The United States Department Of Energy Colloid labelled with radionuclide and method
EP0614377A1 (fr) * 1991-11-14 1994-09-14 Battelle Memorial Institute Procede de diagnostic et de traitement du cancer
JPH08510250A (ja) * 1993-05-17 1996-10-29 イムノメディクス，インコーポレイテッド ビオチンまたはアビジンと金属キレート化タンパク質との複合体による病変の検出および治療法の改善
US5809394A (en) * 1996-12-13 1998-09-15 Battelle Memorial Institute Methods of separating short half-life radionuclides from a mixture of radionuclides
US6117413A (en) * 1997-11-12 2000-09-12 Battelle Memorial Institute Radionuclide-binding compound, a radionuclide delivery system, a method of making a radium complexing compound, a method of extracting a radionuclide, and a method of delivering a radionuclide
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
US20060228297A1 (en) * 2003-04-15 2006-10-12 Roy Larsen Thorium-227 for use in radiotherapy of soft tissue disease

Also Published As

Publication number Publication date
NO990001L (no) 2000-07-05
ATE331534T1 (de) 2006-07-15
LU92425I2 (fr) 2014-06-10
HK1090750A1 (en) 2006-12-29
DE69932183T2 (de) 2007-05-16
CN1335779A (zh) 2002-02-13
NO990001D0 (no) 1999-01-04
WO2000040275A2 (fr) 2000-07-13
NZ534618A (en) 2006-03-31
PT1140212E (pt) 2006-11-30
EP1140212B1 (fr) 2006-06-28
CY2014020I2 (el) 2015-12-09
ES2268888T3 (es) 2007-03-16
JP5433490B2 (ja) 2014-03-05
NO2014010I1 (no) 2014-06-02
EA200100642A1 (ru) 2002-02-28
TR200102707T2 (tr) 2002-03-21
IL144135A0 (en) 2002-05-23
JP4649044B2 (ja) 2011-03-09
MXPA01006823A (es) 2003-07-14
CN1194764C (zh) 2005-03-30
AU1700400A (en) 2000-07-24
US20030206857A1 (en) 2003-11-06
DE69932183D1 (de) 2006-08-10
KR20010092772A (ko) 2001-10-26
TR200201440T2 (tr) 2002-08-21
KR100671387B1 (ko) 2007-01-19
BR9916768A (pt) 2001-12-04
AU774991B2 (en) 2004-07-15
ZA200105431B (en) 2002-07-02
JP2002534399A (ja) 2002-10-15
CY2014020I1 (el) 2015-12-09
NZ545023A (en) 2007-08-31
JP2010168397A (ja) 2010-08-05
EP1140212A2 (fr) 2001-10-10
NO310544B1 (no) 2001-07-23
NO2014010I2 (fr) 2014-05-09
DK1140212T3 (da) 2006-10-09
EA003496B1 (ru) 2003-06-26
CY1105634T1 (el) 2010-12-22
TR200201442T2 (tr) 2002-08-21
NZ513135A (en) 2004-09-24
CN1767078A (zh) 2006-05-03
CA2358498A1 (fr) 2000-07-13
US6635234B1 (en) 2003-10-21
CN1767078B (zh) 2012-01-11
WO2000040275A3 (fr) 2001-06-21
CA2358498C (fr) 2008-09-16

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