NO990001L - Fremstilling og bruk av Radium-223 ved behandling av forkalket vev i forbindelse med smertelindring, ved benkreft og behandling av benoverflaten - Google Patents

Fremstilling og bruk av Radium-223 ved behandling av forkalket vev i forbindelse med smertelindring, ved benkreft og behandling av benoverflaten

Info

Publication number
NO990001L
NO990001L NO990001A NO990001A NO990001L NO 990001 L NO990001 L NO 990001L NO 990001 A NO990001 A NO 990001A NO 990001 A NO990001 A NO 990001A NO 990001 L NO990001 L NO 990001L
Authority
NO
Norway
Prior art keywords
treatment
bone
radium
preparation
connection
Prior art date
Application number
NO990001A
Other languages
English (en)
Other versions
NO990001D0 (no
NO310544B1 (no
Inventor
Roy H Larsen
Gjermund Henriksen
Original Assignee
Anti Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anti Cancer filed Critical Anti Cancer
Priority to NO990001A priority Critical patent/NO310544B1/no
Publication of NO990001D0 publication Critical patent/NO990001D0/no
Priority to TR2002/01442T priority patent/TR200201442T2/xx
Priority to DK99960058T priority patent/DK1140212T3/da
Priority to CA002358498A priority patent/CA2358498C/en
Priority to NZ513135A priority patent/NZ513135A/en
Priority to BR9916768-9A priority patent/BR9916768A/pt
Priority to IL14413599A priority patent/IL144135A0/xx
Priority to CNB998161020A priority patent/CN1194764C/zh
Priority to EA200100642A priority patent/EA003496B1/ru
Priority to TR2002/01440T priority patent/TR200201440T2/xx
Priority to NZ534618A priority patent/NZ534618A/xx
Priority to AU17004/00A priority patent/AU774991B2/en
Priority to KR1020017008497A priority patent/KR100671387B1/ko
Priority to CN2004100749238A priority patent/CN1767078B/zh
Priority to MXPA01006823A priority patent/MXPA01006823A/es
Priority to AT99960058T priority patent/ATE331534T1/de
Priority to PT99960058T priority patent/PT1140212E/pt
Priority to ES99960058T priority patent/ES2268888T3/es
Priority to DE69932183T priority patent/DE69932183T2/de
Priority to PCT/NO1999/000392 priority patent/WO2000040275A2/en
Priority to TR2001/02707T priority patent/TR200102707T2/xx
Priority to NZ545023A priority patent/NZ545023A/en
Priority to EP99960058A priority patent/EP1140212B1/en
Priority to JP2000592029A priority patent/JP4649044B2/ja
Priority to US09/476,569 priority patent/US6635234B1/en
Publication of NO990001L publication Critical patent/NO990001L/no
Priority to ZA200105431A priority patent/ZA200105431B/en
Publication of NO310544B1 publication Critical patent/NO310544B1/no
Priority to US10/459,941 priority patent/US20030206857A1/en
Priority to CY20061101404T priority patent/CY1105634T1/el
Priority to HK06112108.8A priority patent/HK1090750A1/xx
Priority to JP2010096736A priority patent/JP5433490B2/ja
Priority to LU92425C priority patent/LU92425I2/fr
Priority to BE2014C028C priority patent/BE2014C028I2/fr
Priority to NO2014010C priority patent/NO2014010I1/no
Priority to CY2014020C priority patent/CY2014020I1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO990001A 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben NO310544B1 (no)

Priority Applications (34)

Application Number Priority Date Filing Date Title
NO990001A NO310544B1 (no) 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
JP2000592029A JP4649044B2 (ja) 1999-01-04 1999-12-17 ラジウム−223の製造方法及びラジウム−223を含むキット
PT99960058T PT1140212E (pt) 1999-01-04 1999-12-17 Utilização do rádio -223 em tecidos alvo calcificados, para paliação da dor e terapia do cancro ósseo
DE69932183T DE69932183T2 (de) 1999-01-04 1999-12-17 ANWENDUNG VON ZIELGERICHTETEM RADIUM 223 FüR PALLIATIVE UND THERAPEUTISCHE BEHANDLUNG VON KNOCHENKREBS
CA002358498A CA2358498C (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
DK99960058T DK1140212T3 (da) 1999-01-04 1999-12-17 Målrettet anvendelse af radium 223 mod kalkholdigt væv til lettelse af smerter ved behandling af knoglekræft
BR9916768-9A BR9916768A (pt) 1999-01-04 1999-12-17 Métodos para produção de rádio-223 para usosbiomédicos e para tratamento profilático outerapêutico de doneça não maligna ou malignaafetando os ossos e tecidos macios em ummamìfero, preparação fisiologicamente aceitávelpara administração in vivo, uso de rádio-223, e, kit
PCT/NO1999/000392 WO2000040275A2 (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
CNB998161020A CN1194764C (zh) 1999-01-04 1999-12-17 镭-223在制备用于治疗影响骨的疾病的药物中的用途
EA200100642A EA003496B1 (ru) 1999-01-04 1999-12-17 Применение радия-223 для направленной доставки к кальцифицированным тканям в целях временного ослабления боли, терапии рака кости и кондиционирования костной поверхности
TR2002/01440T TR200201440T2 (tr) 1999-01-04 1999-12-17 Biomedikal kullanım için radyum-223 hazırlanması
NZ534618A NZ534618A (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
AU17004/00A AU774991B2 (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
KR1020017008497A KR100671387B1 (ko) 1999-01-04 1999-12-17 석회화된 조직을 표적으로 하는, 통증 완화, 뼈 암 치료,및 뼈 표면 조절용 라듐-223의 제조 및 용도
CN2004100749238A CN1767078B (zh) 1999-01-04 1999-12-17 制备镭-223的方法、生理学上可接受的制剂和试剂盒
MXPA01006823A MXPA01006823A (es) 1999-01-04 1999-12-17 Preparacion y uso de radio-223 para marcar tejidos calcificados para el alivio del dolor, terapia para el cancer de huesos, y acondicionamiento de la superficie de los huesos.
AT99960058T ATE331534T1 (de) 1999-01-04 1999-12-17 Anwendung von zielgerichtetem radium 223 für palliative und therapeutische behandlung von knochenkrebs
TR2002/01442T TR200201442T2 (tr) 1999-01-04 1999-12-17 Ağrı hafifletme, kemik kanseri terapisi ve kemik yüzeyinin sağlıklı tutulması için kireçlenmiş hedef dokulara yönelik radyum-223 hazırlanması ve kullanımı.
ES99960058T ES2268888T3 (es) 1999-01-04 1999-12-17 El uso de radio-223 para dirigirse a tejidos calcificados para paliacion del dolor y terapia de cancer oseo.
NZ513135A NZ513135A (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
IL14413599A IL144135A0 (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
TR2001/02707T TR200102707T2 (tr) 1999-01-04 1999-12-17 AĞrì hafifletme, kemik kanseri terapisi ve kemik yzeyinin saĞlìklì tutulmasì i‡in kire‡lenmiç hedef dokulara y”nelik radyum-223 hazìrlanmasì ve kullanìmì.
NZ545023A NZ545023A (en) 1999-01-04 1999-12-17 Preparation comprising dissolved radium-223
EP99960058A EP1140212B1 (en) 1999-01-04 1999-12-17 The use of radium-223 to target calcified tissues for pain palliation and therapy of bone cancer
US09/476,569 US6635234B1 (en) 1999-01-04 2000-01-03 Preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
ZA200105431A ZA200105431B (en) 1999-01-04 2001-07-02 The preparation and use of radium-233 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning.
US10/459,941 US20030206857A1 (en) 1999-01-04 2003-06-12 Preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
CY20061101404T CY1105634T1 (el) 1999-01-04 2006-09-28 Η χρηση του ραδιου -223 για τη στοχευση ασβεστωμενων ιστων για την ανακουφιση πονου και τη θεραπεια οστικου καρκινου
HK06112108.8A HK1090750A1 (en) 1999-01-04 2006-11-02 Methods of preparing radium-223, and pharmaceutically acceptable agents and reagent set
JP2010096736A JP5433490B2 (ja) 1999-01-04 2010-04-20 石灰化組織を標的とする痛みの緩和、骨癌の治療および骨表面の調節のためのラジウム−223の製剤および使用
LU92425C LU92425I2 (fr) 1999-01-04 2014-04-09 Dichlorure de radium Ra 2232 et ses dérivés pharmaceutiquement acceptables (XOFIGO®)
BE2014C028C BE2014C028I2 (no) 1999-01-04 2014-05-07
NO2014010C NO2014010I1 (no) 1999-01-04 2014-05-09 Radium 223 salt slik som Radium 223 diklorid
CY2014020C CY2014020I1 (el) 1999-01-04 2014-05-13 Η χρηση του ραδιου -223 για τη στοχευση ασβεστωμενων ιστων για την ανακουφιση πονου και τη θεραπεια οστικου καρκινου

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO990001A NO310544B1 (no) 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben

Publications (3)

Publication Number Publication Date
NO990001D0 NO990001D0 (no) 1999-01-04
NO990001L true NO990001L (no) 2000-07-05
NO310544B1 NO310544B1 (no) 2001-07-23

Family

ID=19902803

Family Applications (2)

Application Number Title Priority Date Filing Date
NO990001A NO310544B1 (no) 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO2014010C NO2014010I1 (no) 1999-01-04 2014-05-09 Radium 223 salt slik som Radium 223 diklorid

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2014010C NO2014010I1 (no) 1999-01-04 2014-05-09 Radium 223 salt slik som Radium 223 diklorid

Country Status (25)

Country Link
US (2) US6635234B1 (no)
EP (1) EP1140212B1 (no)
JP (2) JP4649044B2 (no)
KR (1) KR100671387B1 (no)
CN (2) CN1194764C (no)
AT (1) ATE331534T1 (no)
AU (1) AU774991B2 (no)
BE (1) BE2014C028I2 (no)
BR (1) BR9916768A (no)
CA (1) CA2358498C (no)
CY (2) CY1105634T1 (no)
DE (1) DE69932183T2 (no)
DK (1) DK1140212T3 (no)
EA (1) EA003496B1 (no)
ES (1) ES2268888T3 (no)
HK (1) HK1090750A1 (no)
IL (1) IL144135A0 (no)
LU (1) LU92425I2 (no)
MX (1) MXPA01006823A (no)
NO (2) NO310544B1 (no)
NZ (3) NZ513135A (no)
PT (1) PT1140212E (no)
TR (3) TR200102707T2 (no)
WO (1) WO2000040275A2 (no)
ZA (1) ZA200105431B (no)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO313180B1 (no) 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
AUPQ923100A0 (en) * 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
CA2472578A1 (en) * 2002-01-24 2003-07-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Anti-cancer combination and use thereof
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
ATE424221T1 (de) 2003-04-30 2009-03-15 Univ Ramot Verfahren und vorrichtung für strahlentherapie
EP1735013B1 (en) * 2004-02-20 2012-02-08 Algeta ASA Alpha- and beta-emitting hydroxyapatite particles
DE102004022200B4 (de) * 2004-05-05 2006-07-20 Actinium Pharmaceuticals, Inc. Radium-Target sowie Verfahren zu seiner Herstellung
US7914766B1 (en) * 2004-06-03 2011-03-29 Ut-Battelle Llc Inorganic resins for clinical use of 213Bi generators
GB0423565D0 (en) * 2004-10-22 2004-11-24 Algeta As Formulation
CA2615589A1 (en) * 2005-07-26 2007-02-01 Ramot At Tel Aviv University Ltd. A radioactive surface source and a method for producing the same
US8709380B1 (en) * 2006-02-07 2014-04-29 Sirius Medicine, Llc Targeting agents for enhancing radiation therapy
DE102006008023B4 (de) * 2006-02-21 2008-05-29 Actinium Pharmaceuticals, Inc. Verfahren zum Reinigen von 225Ac aus bestrahlten 226Ra-Targets
WO2008028664A1 (en) 2006-09-08 2008-03-13 Actinium Pharmaceuticals, Inc. Method for the purification of radium from different sources
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
EP2353598A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for use in the prevention and/or treatment of postoperative pain
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201007353D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
GB201007354D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
WO2014095833A1 (en) 2012-12-19 2014-06-26 Bayer Pharma Aktiengesellschaft Combination comprising radium-223 for the treatment of cancer
GB201314718D0 (en) * 2013-08-16 2013-10-02 Algeta As Quantification method
EP3077002B1 (en) 2013-12-03 2020-04-22 Bayer Pharma Aktiengesellschaft Combination of pi3k-inhibitors
WO2015082378A1 (en) 2013-12-03 2015-06-11 Bayer Pharma Aktiengesellschaft Combination of pi3k-inhibitors
JP2016540771A (ja) 2013-12-17 2016-12-28 ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ セロトニン−ノルアドレナリン再取り込み阻害薬(snri)およびシグマ受容体リガンドの組み合わせ
WO2016083739A1 (fr) 2014-11-26 2016-06-02 Rhodia Operations Composition de lanthane et d'actinium-227
GB201600153D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
GB201600154D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
CZ2016821A3 (cs) * 2016-12-22 2018-07-04 České vysoké učení technické v Praze Kombinace pro radionuklidovou terapii pro použití jako léčivo
WO2018153969A1 (en) 2017-02-24 2018-08-30 Bayer Aktiengesellschaft Combination of atr kinase inhibitors with radium-223 salt
JP7232489B2 (ja) 2017-05-11 2023-03-03 アルファ タウ メディカル リミテッド 近接照射療法用装置のためのポリマー被覆
MX2020009940A (es) 2018-04-02 2020-10-16 Alpha Tau Medical Ltd Liberacion controlada de radionucleidos.
EP3563875A1 (en) * 2018-05-04 2019-11-06 Ceské vysoké ucení technické v Praze Radium for radionuclide therapy, in combination with calcium metabolism affecting treatment
LU100900B1 (de) * 2018-08-10 2020-02-17 Thomas Melchior Homann Verbindungen zur modulation von a-ketoglutarsäure (2kg)-abhängigen oxygenasen
FR3086186B1 (fr) * 2018-09-26 2022-01-28 Orano Med Procede de production de plomb-212 a partir d'une solution aqueuse comprenant du thorium-228 et ses descendants
FR3088769B1 (fr) * 2018-11-15 2020-12-25 Orano Med Procede de preparation d'au moins un generateur a haute teneur en radium-228
US20220152228A1 (en) * 2019-03-01 2022-05-19 Washington University Compositions and methods for radiotherapy using chelated radiotherapeutic agents and non-target tissue blockade
RU2752845C1 (ru) * 2020-05-13 2021-08-11 Акционерное Общество "Наука И Инновации" Способ получения высокочистого радия-223
AU2021400142A1 (en) * 2020-12-16 2023-06-22 Alpha Tau Medical Ltd. Diffusing alpha-emitters radiation therapy with enhanced beta treatment
CN113066598B (zh) * 2021-03-25 2023-08-08 中国科学院近代物理研究所 一种从高能质子束辐照232Th靶引起的散裂反应中分离纯化223Ra的方法
US12070620B2 (en) 2021-06-10 2024-08-27 Alpha Tau Medical Ltd. Activity levels for diffusing alpha-emitter radiation therapy
US11964168B2 (en) 2021-06-10 2024-04-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for prostate cancer
US12076581B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for glioblastoma
US12076583B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for melanoma
US12064643B2 (en) 2021-06-10 2024-08-20 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for breast cancer
US12076582B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for colorectal cancer
US12042668B2 (en) 2021-06-10 2024-07-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for squamous cell carcinoma
US12070621B2 (en) 2021-06-10 2024-08-27 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for pancreatic cancer
WO2023159230A1 (en) 2022-02-21 2023-08-24 Bayer Healthcare Llc System, method and device for delivery of a therapeutic or diagnostic agent
WO2023159229A1 (en) 2022-02-21 2023-08-24 Bayer Healthcare Llc System, method and device for delivery of a therapeutic or diagnostic agent
CN115869658A (zh) * 2022-12-29 2023-03-31 中国核动力研究设计院 用于制备Ra-223的分离系统及其分离方法、应用和制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH668489A5 (de) * 1982-01-22 1988-12-30 Vnii Mineralnogo Syrya Radiometrisches verfahren zur bestimmung der konzentration natuerlicher radiumisotope und einrichtung zur durchfuehrung des verfahrens.
WO1990003803A1 (en) * 1988-10-14 1990-04-19 Mallinckrodt, Inc. Radiolabelled particulate composition
US4970062A (en) * 1989-05-30 1990-11-13 The United States Of America As Represented By The United States Department Of Energy Colloid labelled with radionuclide and method
CA2123588A1 (en) * 1991-11-14 1993-05-27 Frederick C. Leung Method for diagnosing and treating cancer
JPH08510250A (ja) * 1993-05-17 1996-10-29 イムノメディクス,インコーポレイテッド ビオチンまたはアビジンと金属キレート化タンパク質との複合体による病変の検出および治療法の改善
US5809394A (en) * 1996-12-13 1998-09-15 Battelle Memorial Institute Methods of separating short half-life radionuclides from a mixture of radionuclides
US6117413A (en) * 1997-11-12 2000-09-12 Battelle Memorial Institute Radionuclide-binding compound, a radionuclide delivery system, a method of making a radium complexing compound, a method of extracting a radionuclide, and a method of delivering a radionuclide
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
US20060228297A1 (en) * 2003-04-15 2006-10-12 Roy Larsen Thorium-227 for use in radiotherapy of soft tissue disease

Also Published As

Publication number Publication date
DK1140212T3 (da) 2006-10-09
WO2000040275A2 (en) 2000-07-13
US6635234B1 (en) 2003-10-21
NO990001D0 (no) 1999-01-04
CY2014020I2 (el) 2015-12-09
BE2014C028I2 (no) 2019-03-05
NO2014010I2 (no) 2014-05-09
JP2002534399A (ja) 2002-10-15
PT1140212E (pt) 2006-11-30
ZA200105431B (en) 2002-07-02
EP1140212B1 (en) 2006-06-28
NZ545023A (en) 2007-08-31
NO310544B1 (no) 2001-07-23
JP2010168397A (ja) 2010-08-05
JP5433490B2 (ja) 2014-03-05
CN1767078A (zh) 2006-05-03
MXPA01006823A (es) 2003-07-14
CY1105634T1 (el) 2010-12-22
CN1335779A (zh) 2002-02-13
ATE331534T1 (de) 2006-07-15
TR200201442T2 (tr) 2002-08-21
AU774991B2 (en) 2004-07-15
CN1194764C (zh) 2005-03-30
LU92425I2 (fr) 2014-06-10
NO2014010I1 (no) 2014-06-02
DE69932183T2 (de) 2007-05-16
CA2358498C (en) 2008-09-16
BR9916768A (pt) 2001-12-04
WO2000040275A3 (en) 2001-06-21
KR20010092772A (ko) 2001-10-26
NZ513135A (en) 2004-09-24
CN1767078B (zh) 2012-01-11
HK1090750A1 (en) 2006-12-29
DE69932183D1 (de) 2006-08-10
EA200100642A1 (ru) 2002-02-28
TR200201440T2 (tr) 2002-08-21
US20030206857A1 (en) 2003-11-06
AU1700400A (en) 2000-07-24
NZ534618A (en) 2006-03-31
IL144135A0 (en) 2002-05-23
CY2014020I1 (el) 2015-12-09
ES2268888T3 (es) 2007-03-16
KR100671387B1 (ko) 2007-01-19
JP4649044B2 (ja) 2011-03-09
EA003496B1 (ru) 2003-06-26
EP1140212A2 (en) 2001-10-10
CA2358498A1 (en) 2000-07-13
TR200102707T2 (tr) 2002-03-21

Similar Documents

Publication Publication Date Title
NO990001D0 (no) Fremstilling og bruk av Radium-223 ved behandling av forkalket vev i forbindelse med smertelindring, ved benkreft og behandling av benoverflaten
DE50014411D1 (de) Medizinisches instrument zur abtragung von gewebe, knochenzement oder dergleichen im menschlichen oder tierischen körper
CY1105818T1 (el) Χρησεις του et743 στην θepαπευτικη αγωγη του καρκινου
MXPA03006771A (es) Anticuerpos modificados y metodos de uso.
EP1143943A3 (en) P53 inhibitors and their use for the treatment of cancer, hyperthermia, hypoxia, a burn, trauma to the central nervous system, a seizure, acute inflammation, tissue ageing, preservation of organs for transplant and preparation of a host for bone marrow transplant
FR2721198B1 (fr) Prothèse implantable souple, utilisée en chirurgie pour l'augmentation de volume ou la reconstruction des tissus mous, notamment prothèse mammaire.
HK1047707A1 (zh) (+)-曲馬朵、o-去甲曲馬朵或(+)-o-去甲曲馬朵、o-去甲-n-單-去甲-曲馬朵或(+)-o-去甲-n-單-去甲-曲馬朵治療尿失禁的用途
AU2001234831A1 (en) Magnetoliposome composition for targeted treatment of biological tissue and associated methods
EP1139750A4 (en) BONE SIALOPROTEIN-BASED TOXIC GENE THERAPY FOR TREATING CALCIFIED TUMORS AND TISSUES
WO2004075977A3 (en) Methods using diffuse field ultrasound-induced hyperthermia
UA32302A (uk) Спосіб усунення післяопераційних деформацій м'яких тканин
UA32173A (uk) Спосіб лікування недорозвиненої середньої зони лицевого скелету
UA33571A (uk) Спосіб лікування травматичного перелому нижньої щелепи
SI1196159T1 (en) Use of tosylchloramide(s) for treating diseases of the skin, mucous membranes, organs and tissues
MD1268B2 (en) Method for surgical treatment of meta-physar fracture of children should bone distal part
UA36490A (uk) Спосіб лікування гнійно-септичних захворювань м'яких тканин
UA42335A (uk) Спосіб лікування гнійних ран
UA32174A (uk) Спосіб хірургічного лікування гемангіом надбровної області
UA32153A (uk) Спосіб формування трансплантату для зведення на промежину при черевно-анальних резекціях прямої кишки
UA23316A (uk) Спосіб хірургічhого лікуваhhя відсічhого остеохоhдрозу медіальhого виростка стегhової кістки
UA36452A (uk) Спосіб декомпресивної трепанації черепа
UA32109A (uk) Спосіб пластики фарингоезофагостоми
UA29185A (uk) Спосіб лікування стенокардії
UA33359A (uk) Спосіб доступу до пухлин орбіти
UA34192A (uk) Спосіб остеосинтезу фрагментів довгих кісток та пристрій для його здійснення

Legal Events

Date Code Title Description
SPCG Granted supplementary protection certificate

Free format text: PRODUCT NAME: XOFIGO; REG.NO/DATE: EU/1/13/873/001 2013.11.13 FIRST REG.NO/DATE: EU/1/13/873/001 2013.11.13

Spc suppl protection certif: 2014010

Filing date: 20140509

Extension date: 20240104

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BAYER AS, NO

CREP Change of representative

Representative=s name: ONSAGERS AS, POSTBOKS 1813 VIKA, 0123 OSLO, NORGE

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BAYER AS, NO

MK1K Patent expired
SPCX Expiry of an spc

Spc suppl protection certif: 2014010

Expiry date: 20240104