JP2002520067A5 - - Google Patents
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- Publication number
- JP2002520067A5 JP2002520067A5 JP2000560279A JP2000560279A JP2002520067A5 JP 2002520067 A5 JP2002520067 A5 JP 2002520067A5 JP 2000560279 A JP2000560279 A JP 2000560279A JP 2000560279 A JP2000560279 A JP 2000560279A JP 2002520067 A5 JP2002520067 A5 JP 2002520067A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- glucosamine
- nucleic acid
- phosphate
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 description 18
- 102000004894 Glutamine-fructose-6-phosphate transaminase (isomerizing) Human genes 0.000 description 9
- 108090001031 Glutamine-fructose-6-phosphate transaminase (isomerizing) Proteins 0.000 description 9
- 108091028043 Nucleic acid sequence Proteins 0.000 description 9
- 108020004707 nucleic acids Proteins 0.000 description 9
- 102000039446 nucleic acids Human genes 0.000 description 9
- 244000005700 microbiome Species 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 238000012239 gene modification Methods 0.000 description 6
- 230000005017 genetic modification Effects 0.000 description 6
- 235000013617 genetically modified food Nutrition 0.000 description 6
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 description 4
- 229960002442 glucosamine Drugs 0.000 description 4
- 125000003275 alpha amino acid group Chemical group 0.000 description 3
- 238000012258 culturing Methods 0.000 description 3
- XHMJOUIAFHJHBW-VFUOTHLCSA-N glucosamine 6-phosphate Chemical compound N[C@H]1[C@H](O)O[C@H](COP(O)(O)=O)[C@H](O)[C@@H]1O XHMJOUIAFHJHBW-VFUOTHLCSA-N 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 102100031317 Alpha-N-acetylgalactosaminidase Human genes 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- 101710128527 DNA-directed RNA polymerase subunit alpha Proteins 0.000 description 1
- 101710112941 DNA-directed RNA polymerase subunit beta Proteins 0.000 description 1
- 101710126019 DNA-directed RNA polymerase subunit beta C-terminal section Proteins 0.000 description 1
- 101710122417 DNA-directed RNA polymerase subunit beta N-terminal section Proteins 0.000 description 1
- 101710185074 DNA-directed RNA polymerase subunit beta' Proteins 0.000 description 1
- 101710135457 DNA-directed RNA polymerase subunit beta'' Proteins 0.000 description 1
- 102100041034 Glucosamine-6-phosphate isomerase 1 Human genes 0.000 description 1
- 102100029880 Glycodelin Human genes 0.000 description 1
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 description 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 description 1
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 description 1
- 108010069483 N-acetylglucosamine-6-phosphate deacetylase Proteins 0.000 description 1
- 102000001105 Phosphofructokinases Human genes 0.000 description 1
- 108010069341 Phosphofructokinases Proteins 0.000 description 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
- 101710154444 Putative DNA-directed RNA polymerase subunit omega Proteins 0.000 description 1
- 102000004357 Transferases Human genes 0.000 description 1
- 108090000992 Transferases Proteins 0.000 description 1
- 101710116223 Tyrosine-protein phosphatase non-receptor type 22 Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- YMJBYRVFGYXULK-QZABAPFNSA-N alpha-D-glucosamine 1-phosphate Chemical compound N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(O)=O YMJBYRVFGYXULK-QZABAPFNSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 108010022717 glucosamine-6-phosphate isomerase Proteins 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 229950006780 n-acetylglucosamine Drugs 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 108010032867 phosphoglucosamine mutase Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/115,475 | 1998-07-15 | ||
| US09/115,475 US6372457B1 (en) | 1997-01-14 | 1998-07-15 | Process and materials for production of glucosamine |
| PCT/US1999/015976 WO2000004182A1 (en) | 1998-07-15 | 1999-07-15 | Process and materials for production of glucosamine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010110574A Division JP2010166934A (ja) | 1998-07-15 | 2010-05-12 | グルコサミンを製造するためのプロセス及び物質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002520067A JP2002520067A (ja) | 2002-07-09 |
| JP2002520067A5 true JP2002520067A5 (https=) | 2006-09-07 |
| JP4567887B2 JP4567887B2 (ja) | 2010-10-20 |
Family
ID=22361646
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000560279A Expired - Lifetime JP4567887B2 (ja) | 1998-07-15 | 1999-07-15 | グルコサミンを製造するためのプロセス及び物質 |
| JP2010110574A Withdrawn JP2010166934A (ja) | 1998-07-15 | 2010-05-12 | グルコサミンを製造するためのプロセス及び物質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010110574A Withdrawn JP2010166934A (ja) | 1998-07-15 | 2010-05-12 | グルコサミンを製造するためのプロセス及び物質 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US6372457B1 (https=) |
| EP (1) | EP1095158B1 (https=) |
| JP (2) | JP4567887B2 (https=) |
| CN (1) | CN100491524C (https=) |
| AT (1) | ATE414162T1 (https=) |
| AU (1) | AU5102899A (https=) |
| CA (1) | CA2332380C (https=) |
| DE (1) | DE69939901D1 (https=) |
| WO (1) | WO2000004182A1 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020160459A1 (en) * | 1997-01-14 | 2002-10-31 | Alan Berry | Process for production of n-glucosamine |
| US6372457B1 (en) * | 1997-01-14 | 2002-04-16 | Arkion Life Sciences Llc | Process and materials for production of glucosamine |
| CA2313836C (en) | 2000-03-15 | 2009-06-09 | Cargill, Incorporated | Chitosan and method of preparing chitosan |
| US7923437B2 (en) * | 2001-02-16 | 2011-04-12 | Cargill, Incorporated | Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same |
| US6693188B2 (en) | 2001-08-08 | 2004-02-17 | Cargill Incorporated | N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine |
| US8222232B2 (en) * | 2001-02-16 | 2012-07-17 | Cargill, Incorporated | Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass |
| US20020115639A1 (en) | 2001-02-16 | 2002-08-22 | Weiyu Fan | Glucosamine and method of making glucosamine from microbial blomass |
| US7816514B2 (en) | 2001-02-16 | 2010-10-19 | Cargill, Incorporated | Glucosamine and method of making glucosamine from microbial biomass |
| DE60210772T2 (de) * | 2001-07-06 | 2007-04-12 | Degussa Ag | Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen der familie enterobacteriaceae |
| EP1497335A4 (en) | 2002-04-02 | 2009-08-12 | Cargill Inc | PREPARATION OF CHITOSAN |
| KR101035043B1 (ko) * | 2002-07-01 | 2011-05-19 | 아르키온 라이프 사이언씨즈 엘엘씨 | 글루코사민 및 ｎ-아세틸글루코사민의 제조를 위한 물질및 공정 |
| PA8576201A1 (es) | 2002-07-10 | 2004-05-26 | Pfizer Prod Inc | Composicion farmaceutica que tiene una distribucion y potencia uniforme de farmaco |
| RU2005113312A (ru) * | 2002-09-30 | 2005-10-10 | Ачер-Дэниелс-Мидленд Компани (Us) | Бесклеточное получение глюкозамина |
| US20050239173A1 (en) * | 2003-12-08 | 2005-10-27 | Cargill, Inc. | Production of amino sugars |
| US20070212764A1 (en) * | 2005-01-19 | 2007-09-13 | Ptitsyn Leonid R | Method for producing l-amino acids using bacterium of the enterobacteriaceae family |
| CA2607496C (en) * | 2005-05-13 | 2013-12-10 | Nestec S.A. | Production of glucosamine from plant species |
| ES2376114T3 (es) * | 2005-05-13 | 2012-03-09 | Nestec S.A. | Producción de glucosamina a partir de especies vegetales. |
| WO2008111507A1 (ja) * | 2007-03-09 | 2008-09-18 | Kyowa Hakko Bio Co., Ltd. | 改変されたグルコサミン-6-リン酸合成酵素 |
| WO2008119009A2 (en) * | 2007-03-27 | 2008-10-02 | University Of Florida Research Foundation, Inc. | Materials and methods for efficient alanine production |
| WO2008144060A2 (en) | 2007-05-17 | 2008-11-27 | Tetravitae Bioscience, Inc. | Methods and compositions for producing solvents |
| JP5424604B2 (ja) * | 2008-09-30 | 2014-02-26 | 協和発酵バイオ株式会社 | グルコサミンの製造法 |
| EP2348101B1 (en) | 2008-10-20 | 2016-05-04 | CJ CheilJedang Corporation | Corynebacterium genus microorganism having ability to produce n-acetyl glucosamine and method for producing n-acetyl glucosamine or glucosamine using same |
| WO2010123784A2 (en) * | 2009-04-24 | 2010-10-28 | New England Biolabs, Inc. | Conversion of chitin into n-acetylglucosamine, glucosamine and bioethanol |
| US20120329135A1 (en) | 2011-06-23 | 2012-12-27 | Agrinos AS | Process for Making Chitin Derivatives |
| US10227368B2 (en) | 2013-11-05 | 2019-03-12 | Nestec S.A. | Generation of glucosamine from plant material |
| CN104988196A (zh) * | 2015-07-30 | 2015-10-21 | 安徽丰原发酵技术工程研究有限公司 | 一种n-乙酰氨基葡萄糖的发酵生产方法 |
| CN107267577A (zh) | 2016-04-05 | 2017-10-20 | 孙镧 | 微生物发酵生产n‑乙酰‑d‑氨基葡萄糖和/或d‑氨基葡萄糖盐的方法 |
| WO2017174038A1 (zh) * | 2016-04-05 | 2017-10-12 | 孙镧 | 微生物发酵生产n-乙酰-d-氨基葡萄糖和/或d-氨基葡萄糖盐的方法 |
| WO2017174036A1 (zh) * | 2016-04-05 | 2017-10-12 | 孙镧 | 微生物发酵生产n-乙酰-d-氨基葡萄糖和/或d-氨基葡萄糖盐的方法 |
| WO2017174040A1 (zh) * | 2016-04-05 | 2017-10-12 | 孙镧 | 微生物发酵生产n-乙酰-d-氨基葡萄糖和/或d-氨基葡萄糖盐的方法 |
| CN108070628B (zh) * | 2016-11-14 | 2021-08-24 | 中国科学院微生物研究所 | 一种生产氨基葡萄糖的方法 |
| EP3473644A1 (en) * | 2017-10-17 | 2019-04-24 | Jennewein Biotechnologie GmbH | Fermentative production of n-acetylneuraminic acid |
| WO2019158541A1 (en) | 2018-02-14 | 2019-08-22 | Frieslandcampina Nederland B.V. | Nutritional compositions for musculoskeletal support for athletes |
| CN108410783B (zh) * | 2018-05-29 | 2020-11-03 | 成都本则生科技有限公司 | 一种培养大肠杆菌发酵生产氨基葡萄糖的方法 |
| CN110714042A (zh) * | 2018-07-13 | 2020-01-21 | 中国科学院天津工业生物技术研究所 | 氨基葡萄糖的酶法制备 |
| CN110577977A (zh) * | 2019-10-09 | 2019-12-17 | 山东润德生物科技有限公司 | 大肠杆菌发酵生产氨基葡萄糖的方法 |
| IT202100030935A1 (it) | 2021-12-09 | 2023-06-09 | Fidia Farm Spa | Compresse comprendenti condroitin solfato, glucosamina cloridrato e vitamina c per il trattamento di danni cartilaginei, tendinei, ossei |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07179488A (ja) * | 1993-11-12 | 1995-07-18 | Tanabe Seiyaku Co Ltd | グルコサミン誘導体、その製法及びその合成中間体 |
| PT729473E (pt) * | 1993-11-17 | 2001-02-28 | Deutsche Om Arzneimittel Gmbh | Dissacaridos de glucosamina metodo para a sua preparacao composicao farmaceutica contendo os mesmos e sua utilizacao |
| JP2769992B2 (ja) * | 1995-04-25 | 1998-06-25 | 工業技術院長 | グルコサミン−６−ホスフェートデアミナーゼ |
| CA2187386C (en) * | 1995-10-27 | 2007-01-23 | Kaoru Takegawa | Gene encoding endo-.beta.-n-acetylglucosaminidase a |
| US5998173A (en) * | 1996-02-20 | 1999-12-07 | The University Of Bristish Columbia | Process for producing N-acetyl-D-glucosamine |
| JP2824508B2 (ja) * | 1996-03-04 | 1998-11-11 | 工業技術院長 | Ｎ−アセチルグルコサミン６−リン酸デアセチラーゼ |
| US20020160459A1 (en) * | 1997-01-14 | 2002-10-31 | Alan Berry | Process for production of n-glucosamine |
| US6372457B1 (en) * | 1997-01-14 | 2002-04-16 | Arkion Life Sciences Llc | Process and materials for production of glucosamine |
-
1998
- 1998-07-15 US US09/115,475 patent/US6372457B1/en not_active Expired - Lifetime
-
1999
- 1999-07-15 AT AT99935577T patent/ATE414162T1/de not_active IP Right Cessation
- 1999-07-15 CA CA2332380A patent/CA2332380C/en not_active Expired - Lifetime
- 1999-07-15 WO PCT/US1999/015976 patent/WO2000004182A1/en not_active Ceased
- 1999-07-15 CN CNB998100870A patent/CN100491524C/zh not_active Expired - Lifetime
- 1999-07-15 DE DE69939901T patent/DE69939901D1/de not_active Expired - Lifetime
- 1999-07-15 JP JP2000560279A patent/JP4567887B2/ja not_active Expired - Lifetime
- 1999-07-15 EP EP99935577A patent/EP1095158B1/en not_active Expired - Lifetime
- 1999-07-15 AU AU51028/99A patent/AU5102899A/en not_active Abandoned
-
2001
- 2001-12-17 US US10/024,460 patent/US20030044939A1/en not_active Abandoned
-
2005
- 2005-10-05 US US11/245,473 patent/US20060094085A1/en not_active Abandoned
-
2007
- 2007-06-22 US US11/767,394 patent/US20090017520A1/en not_active Abandoned
-
2010
- 2010-05-12 JP JP2010110574A patent/JP2010166934A/ja not_active Withdrawn
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