JP2002516294A - 粘膜免疫を誘導するための方法および産物 - Google Patents
粘膜免疫を誘導するための方法および産物Info
- Publication number
- JP2002516294A JP2002516294A JP2000550515A JP2000550515A JP2002516294A JP 2002516294 A JP2002516294 A JP 2002516294A JP 2000550515 A JP2000550515 A JP 2000550515A JP 2000550515 A JP2000550515 A JP 2000550515A JP 2002516294 A JP2002516294 A JP 2002516294A
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- Prior art keywords
- oligonucleotide
- antigen
- mucosal
- subject
- immune response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Landscapes
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| PCT/US1999/011359 WO1999061056A2 (en) | 1998-05-22 | 1999-05-21 | Methods and products for inducing mucosal immunity |
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| JP2002516294A true JP2002516294A (ja) | 2002-06-04 |
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| SI (1) | SI1077722T1 (https=) |
| WO (1) | WO1999061056A2 (https=) |
| ZA (1) | ZA200006765B (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005014038A1 (ja) * | 2003-08-11 | 2005-02-17 | The Research Foundation For Microbial Diseases Of Osaka University | 粘膜免疫誘導アジュバントを含む新規ワクチン |
| JP2005538957A (ja) * | 2002-06-05 | 2005-12-22 | デュオトル、アクチボラグ | 免疫系を調節するための二官能性組成物およびその使用 |
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| US7935675B1 (en) | 1994-07-15 | 2011-05-03 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US20030026782A1 (en) | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
| US5981501A (en) * | 1995-06-07 | 1999-11-09 | Inex Pharmaceuticals Corp. | Methods for encapsulating plasmids in lipid bilayers |
| EP0855184A1 (en) | 1997-01-23 | 1998-07-29 | Grayson B. Dr. Lipford | Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| CA2289702C (en) * | 1997-05-14 | 2008-02-19 | Inex Pharmaceuticals Corp. | High efficiency encapsulation of charged therapeutic agents in lipid vesicles |
| AU7690898A (en) | 1997-05-20 | 1998-12-11 | Ottawa Civic Hospital Loeb Research Institute | Vectors and methods for immunization or therapeutic protocols |
| US6589940B1 (en) | 1997-06-06 | 2003-07-08 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| PT1077722E (pt) | 1998-05-22 | 2006-12-29 | Coley Pharm Group Inc | Produtos e composições para utilização na indução da imunidade mucosal |
| US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
| US7049302B1 (en) | 1998-08-10 | 2006-05-23 | Antigenics Inc. | Compositions of CPG and saponin adjuvants and uses thereof |
| WO2000045849A2 (en) * | 1999-02-05 | 2000-08-10 | Genzyme Corporation | Use of cationic lipids to generate anti-tumor immunity |
| WO2000048630A1 (en) | 1999-02-17 | 2000-08-24 | Csl Limited | Immunogenic complexes and methods relating thereto |
| AU4343700A (en) * | 1999-04-12 | 2000-11-14 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Oligodeoxynucleotide and its use to induce an immune response |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| US6558670B1 (en) | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
| DE60014076T2 (de) * | 1999-04-19 | 2005-10-13 | Glaxosmithkline Biologicals S.A. | Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid |
| GB9908885D0 (en) * | 1999-04-19 | 1999-06-16 | Smithkline Beecham Biolog | Vccine |
| WO2000062802A2 (en) * | 1999-04-20 | 2000-10-26 | Smithkline Beecham Biologicals Sa | Vaccine comprising rsv antigen and cpg oligonucleotide |
| SK287400B6 (sk) * | 1999-09-25 | 2010-08-09 | University Of Iowa Research Foundation | Prostriedok s obsahom imunostimulačnej nukleovej kyseliny a jeho použitie na stimuláciu imunitnej reakcie |
| US6949520B1 (en) | 1999-09-27 | 2005-09-27 | Coley Pharmaceutical Group, Inc. | Methods related to immunostimulatory nucleic acid-induced interferon |
| EP1239876B1 (en) * | 1999-11-19 | 2008-07-30 | Csl Limited | Hcv vaccine compositions |
| AU781812B2 (en) * | 2000-01-13 | 2005-06-16 | Antigenics, Inc. | Innate immunity-stimulating compositions of CPG and saponin and methods thereof |
| EP1322655B1 (en) | 2000-01-14 | 2007-11-14 | The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| US7585847B2 (en) | 2000-02-03 | 2009-09-08 | Coley Pharmaceutical Group, Inc. | Immunostimulatory nucleic acids for the treatment of asthma and allergy |
| US6653467B1 (en) * | 2000-04-26 | 2003-11-25 | Jcr Pharmaceutical Co., Ltd. | Medicament for treatment of Duchenne muscular dystrophy |
| AU2001270134B2 (en) | 2000-06-22 | 2006-06-15 | University Of Iowa Research Foundation | Methods for enhancing antibody-induced cell lysis and treating cancer |
| WO2002011761A2 (en) * | 2000-08-10 | 2002-02-14 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Vaccine against rsv |
| JP2005500806A (ja) | 2000-09-15 | 2005-01-13 | コーリー ファーマシューティカル ゲーエムベーハー | ＣｐＧに基づく免疫アゴニスト／免疫アンタゴニストの高スループットスクリーニングのためのプロセス |
| PT1889630E (pt) * | 2000-10-18 | 2012-02-29 | Glaxosmithkline Biolog Sa | Vacinas compreendendo o antigénio mage ligado a um fragmento da proteína d |
| JP2004511527A (ja) * | 2000-10-18 | 2004-04-15 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
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| JP2005538957A (ja) * | 2002-06-05 | 2005-12-22 | デュオトル、アクチボラグ | 免疫系を調節するための二官能性組成物およびその使用 |
| JP4937511B2 (ja) * | 2002-06-05 | 2012-05-23 | デュオトル、アクチボラグ | 免疫系を調節するための二官能性組成物およびその使用 |
| WO2005014038A1 (ja) * | 2003-08-11 | 2005-02-17 | The Research Foundation For Microbial Diseases Of Osaka University | 粘膜免疫誘導アジュバントを含む新規ワクチン |
Also Published As
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| DE69932717D1 (de) | 2006-09-21 |
| AU4197799A (en) | 1999-12-13 |
| DK1077722T3 (da) | 2006-11-27 |
| EP1077722B1 (en) | 2006-08-09 |
| WO1999061056A2 (en) | 1999-12-02 |
| BR9910643A (pt) | 2001-10-30 |
| ZA200006765B (en) | 2002-08-22 |
| CY1107337T1 (el) | 2012-12-19 |
| IL139813A (en) | 2007-06-03 |
| DK1733735T3 (en) | 2017-06-19 |
| AU761899B2 (en) | 2003-06-12 |
| EP1077722A2 (en) | 2001-02-28 |
| US8574599B1 (en) | 2013-11-05 |
| PT1733735T (pt) | 2017-06-16 |
| IL139813A0 (en) | 2002-02-10 |
| US20040266719A1 (en) | 2004-12-30 |
| NZ508927A (en) | 2003-12-19 |
| WO1999061056A9 (en) | 2000-06-15 |
| HK1037125A1 (en) | 2002-02-01 |
| EP1733735A3 (en) | 2008-08-27 |
| EP1733735A2 (en) | 2006-12-20 |
| ATE335510T1 (de) | 2006-09-15 |
| CA2328894A1 (en) | 1999-12-02 |
| WO1999061056A3 (en) | 2000-04-06 |
| DE69932717T2 (de) | 2007-08-09 |
| ES2628744T3 (es) | 2017-08-03 |
| EP1733735B1 (en) | 2017-03-22 |
| SI1077722T1 (sl) | 2007-02-28 |
| PT1077722E (pt) | 2006-12-29 |
| ES2272069T3 (es) | 2007-04-16 |
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