JP2002514623A - ドーパミン受容体として有用なフェニルスルホンアミド−フェニルエチルアミン - Google Patents

ドーパミン受容体として有用なフェニルスルホンアミド−フェニルエチルアミン

Info

Publication number
JP2002514623A
JP2002514623A JP2000548303A JP2000548303A JP2002514623A JP 2002514623 A JP2002514623 A JP 2002514623A JP 2000548303 A JP2000548303 A JP 2000548303A JP 2000548303 A JP2000548303 A JP 2000548303A JP 2002514623 A JP2002514623 A JP 2002514623A
Authority
JP
Japan
Prior art keywords
ethyl
propylamine
phenyl
alkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000548303A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002514623A5 (enExample
Inventor
アーサー・グレン・ロメロ
ジェフリー・エイ・ライビー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of JP2002514623A publication Critical patent/JP2002514623A/ja
Publication of JP2002514623A5 publication Critical patent/JP2002514623A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000548303A 1998-05-14 1999-05-07 ドーパミン受容体として有用なフェニルスルホンアミド−フェニルエチルアミン Withdrawn JP2002514623A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8549398P 1998-05-14 1998-05-14
US60/085,493 1998-05-14
PCT/US1999/007023 WO1999058499A1 (en) 1998-05-14 1999-05-07 Phenylsulfonamide-phenylethylamines useful as dopamine receptors

Publications (2)

Publication Number Publication Date
JP2002514623A true JP2002514623A (ja) 2002-05-21
JP2002514623A5 JP2002514623A5 (enExample) 2006-08-10

Family

ID=22191975

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000548303A Withdrawn JP2002514623A (ja) 1998-05-14 1999-05-07 ドーパミン受容体として有用なフェニルスルホンアミド−フェニルエチルアミン

Country Status (24)

Country Link
US (1) US6103766A (enExample)
EP (1) EP1077935B1 (enExample)
JP (1) JP2002514623A (enExample)
KR (1) KR20010043546A (enExample)
CN (1) CN1152857C (enExample)
AT (1) ATE253045T1 (enExample)
AU (1) AU752543B2 (enExample)
BR (1) BR9910405A (enExample)
CA (1) CA2327345A1 (enExample)
DE (1) DE69912419T2 (enExample)
DK (1) DK1077935T3 (enExample)
EA (1) EA002918B1 (enExample)
ES (1) ES2211078T3 (enExample)
HU (1) HUP0101746A3 (enExample)
IL (1) IL139263A0 (enExample)
NO (1) NO20005732D0 (enExample)
NZ (1) NZ508152A (enExample)
PL (1) PL343891A1 (enExample)
PT (1) PT1077935E (enExample)
SK (1) SK16242000A3 (enExample)
TR (1) TR200003325T2 (enExample)
TW (1) TW450954B (enExample)
WO (1) WO1999058499A1 (enExample)
ZA (1) ZA200005921B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008516915A (ja) * 2004-10-14 2008-05-22 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアミノエチル芳香族化合物
JP2008516918A (ja) * 2004-10-14 2008-05-22 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適な複素環化合物
JP2009533397A (ja) * 2006-04-14 2009-09-17 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアリールオキシエチルアミン化合物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT971878E (pt) * 1997-02-27 2008-07-08 Takeda Pharmaceutical Compostos de amina, sua produção e utilização como inibidores da produção de amilóide beta
JP2005508852A (ja) * 2001-05-07 2005-04-07 スミスクライン・ビーチャム・コーポレイション スルホンアミド
WO2002089785A1 (en) * 2001-05-07 2002-11-14 Smithkline Beecham Corporation Sulfonamides
ATE520659T1 (de) 2004-10-14 2011-09-15 Abbott Gmbh & Co Kg Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
TWI400233B (zh) * 2006-04-14 2013-07-01 Abbott Gmbh & Co Kg 適用於治療對多巴胺ｄ3受體之調節有反應的疾病之芳氧基乙胺化合物
JP2009534355A (ja) 2006-04-19 2009-09-24 アボット ゲーエムベーハー ウント カンパニー カーゲー セロトニン５ｈｔ６受容体の調節に応答する障害を治療するために好適な複素環化合物
MX2008013434A (es) 2006-04-19 2009-01-26 Abbott Gmbh & Co Kg Arilsufonas heterociclicas adecuadas para tratar trastornos que responden a la modulacion del receptor de serotonina 5ht6.
WO2008026046A1 (en) * 2006-08-30 2008-03-06 Pfizer Products Inc. Morpholine d3 dopamine antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
GB9402197D0 (en) * 1994-02-04 1994-03-30 Smithkline Beecham Plc Compounds
CN1088062C (zh) * 1994-11-23 2002-07-24 纽罗根公司 某些4－氨基甲基－2－取代的咪唑衍生物2－氨基甲基－4－取代的咪唑衍生物新的一族多巴胺受体亚型特异性配体
EP0917530B1 (en) * 1996-05-11 2003-02-19 SmithKline Beecham plc Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
US5922770A (en) * 1996-07-22 1999-07-13 Novo Nordisk A/S Compounds with growth hormone releasing properties
JPH1180156A (ja) * 1997-09-04 1999-03-26 Hokuriku Seiyaku Co Ltd １−（置換アリール）アルキル−１ｈ−イミダゾピリジン−４−アミン誘導体

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008516915A (ja) * 2004-10-14 2008-05-22 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアミノエチル芳香族化合物
JP2008516918A (ja) * 2004-10-14 2008-05-22 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適な複素環化合物
JP4833989B2 (ja) * 2004-10-14 2011-12-07 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアミノエチル芳香族化合物
JP2012006946A (ja) * 2004-10-14 2012-01-12 Abbott Gmbh & Co Kg ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアミノエチル芳香族化合物
JP2009533397A (ja) * 2006-04-14 2009-09-17 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアリールオキシエチルアミン化合物

Also Published As

Publication number Publication date
HUP0101746A2 (hu) 2002-03-28
NZ508152A (en) 2003-03-28
TW450954B (en) 2001-08-21
PT1077935E (pt) 2004-03-31
SK16242000A3 (sk) 2001-06-11
AU752543B2 (en) 2002-09-19
NO20005732L (no) 2000-11-13
WO1999058499A1 (en) 1999-11-18
TR200003325T2 (tr) 2001-04-20
DE69912419D1 (de) 2003-12-04
PL343891A1 (en) 2001-09-10
EA200001184A1 (ru) 2001-04-23
NO20005732D0 (no) 2000-11-13
EP1077935A1 (en) 2001-02-28
KR20010043546A (ko) 2001-05-25
BR9910405A (pt) 2001-01-09
ES2211078T3 (es) 2004-07-01
EA002918B1 (ru) 2002-10-31
IL139263A0 (en) 2001-11-25
HUP0101746A3 (en) 2002-10-28
CN1297431A (zh) 2001-05-30
EP1077935B1 (en) 2003-10-29
US6103766A (en) 2000-08-15
ZA200005921B (en) 2001-11-14
HK1036049A1 (en) 2001-12-21
ATE253045T1 (de) 2003-11-15
DK1077935T3 (da) 2004-02-16
DE69912419T2 (de) 2004-07-22
CA2327345A1 (en) 1999-11-18
CN1152857C (zh) 2004-06-09
AU3741899A (en) 1999-11-29

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