ATE253045T1 - Phenylsulfonamid-phenylethylamine nützlich als dopamin-rezeptoren - Google Patents
Phenylsulfonamid-phenylethylamine nützlich als dopamin-rezeptorenInfo
- Publication number
- ATE253045T1 ATE253045T1 AT99919771T AT99919771T ATE253045T1 AT E253045 T1 ATE253045 T1 AT E253045T1 AT 99919771 T AT99919771 T AT 99919771T AT 99919771 T AT99919771 T AT 99919771T AT E253045 T1 ATE253045 T1 AT E253045T1
- Authority
- AT
- Austria
- Prior art keywords
- phenylethylamines
- phenylsulfonamide
- useful
- dopamine receptors
- alkyl
- Prior art date
Links
- 102000015554 Dopamine receptor Human genes 0.000 title 1
- 108050004812 Dopamine receptor Proteins 0.000 title 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 101100054666 Streptomyces halstedii sch3 gene Proteins 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 102000004073 Dopamine D3 Receptors Human genes 0.000 abstract 1
- 108090000525 Dopamine D3 Receptors Proteins 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8549398P | 1998-05-14 | 1998-05-14 | |
| PCT/US1999/007023 WO1999058499A1 (en) | 1998-05-14 | 1999-05-07 | Phenylsulfonamide-phenylethylamines useful as dopamine receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE253045T1 true ATE253045T1 (de) | 2003-11-15 |
Family
ID=22191975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99919771T ATE253045T1 (de) | 1998-05-14 | 1999-05-07 | Phenylsulfonamid-phenylethylamine nützlich als dopamin-rezeptoren |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6103766A (de) |
| EP (1) | EP1077935B1 (de) |
| JP (1) | JP2002514623A (de) |
| KR (1) | KR20010043546A (de) |
| CN (1) | CN1152857C (de) |
| AT (1) | ATE253045T1 (de) |
| AU (1) | AU752543B2 (de) |
| BR (1) | BR9910405A (de) |
| CA (1) | CA2327345A1 (de) |
| DE (1) | DE69912419T2 (de) |
| DK (1) | DK1077935T3 (de) |
| EA (1) | EA002918B1 (de) |
| ES (1) | ES2211078T3 (de) |
| HU (1) | HUP0101746A3 (de) |
| IL (1) | IL139263A0 (de) |
| NO (1) | NO20005732L (de) |
| NZ (1) | NZ508152A (de) |
| PL (1) | PL343891A1 (de) |
| PT (1) | PT1077935E (de) |
| SK (1) | SK16242000A3 (de) |
| TR (1) | TR200003325T2 (de) |
| TW (1) | TW450954B (de) |
| WO (1) | WO1999058499A1 (de) |
| ZA (1) | ZA200005921B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2300119T3 (es) * | 1997-02-27 | 2008-06-01 | Takeda Pharmaceutical Company Limited | Compuestos de amina, su produccion y su uso como inhibidores de la produccion de beta-amiloide. |
| EP1385495A4 (de) * | 2001-05-07 | 2005-12-21 | Smithkline Beecham Corp | Sulfonamide |
| US6849635B2 (en) * | 2001-05-07 | 2005-02-01 | Smithkline Beecham Corporation | Sulfonamides |
| CA2583918C (en) | 2004-10-14 | 2013-01-29 | Abbott Gmbh & Co. Kg | Aminoethylaromatic compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor |
| CN101039904B (zh) | 2004-10-14 | 2014-09-24 | Abbvie德国有限责任两合公司 | 适于治疗对于多巴胺d3受体调节有反应的病症的杂环化合物 |
| WO2006040176A1 (en) | 2004-10-14 | 2006-04-20 | Abbott Gmbh & Co. Kg | Azabicycloheptyl compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor |
| JP5232987B2 (ja) * | 2006-04-14 | 2013-07-10 | アボット ゲーエムベーハー ウント カンパニー カーゲー | ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアリールオキシエチルアミン化合物 |
| ES2360254T3 (es) * | 2006-04-14 | 2011-06-02 | ABBOTT GMBH & CO. KG | Compuestos de ariloxietilamina adecuados para tratamiento de trastornos que respondan a la modulación del receptor de dopamina d3. |
| JP2009534354A (ja) | 2006-04-19 | 2009-09-24 | アボット ゲーエムベーハー ウント カンパニー カーゲー | セロトニン５ｈｔ６受容体の調節に応答する障害を治療するために好適な複素環アリールスルホン類 |
| JP2009534355A (ja) | 2006-04-19 | 2009-09-24 | アボット ゲーエムベーハー ウント カンパニー カーゲー | セロトニン５ｈｔ６受容体の調節に応答する障害を治療するために好適な複素環化合物 |
| WO2008026046A1 (en) * | 2006-08-30 | 2008-03-06 | Pfizer Products Inc. | Morpholine d3 dopamine antagonists |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3574741A (en) * | 1969-04-14 | 1971-04-13 | Mead Johnson & Co | Sulfonamidophenalkylamines |
| US5451677A (en) * | 1993-02-09 | 1995-09-19 | Merck & Co., Inc. | Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity |
| GB9402197D0 (en) * | 1994-02-04 | 1994-03-30 | Smithkline Beecham Plc | Compounds |
| AU4368996A (en) * | 1994-11-23 | 1996-06-17 | Neurogen Corporation | Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands |
| CA2253927A1 (en) * | 1996-05-11 | 1997-11-20 | Smithkline Beecham P.L.C. | Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors |
| DE69713109T2 (de) * | 1996-07-22 | 2003-01-02 | Novo Nordisk A/S, Bagsvaerd | Verbindungen mit wachstumshormon freisetzenden eigenschaften |
| JPH1180156A (ja) * | 1997-09-04 | 1999-03-26 | Hokuriku Seiyaku Co Ltd | １−（置換アリール）アルキル−１ｈ−イミダゾピリジン−４−アミン誘導体 |
-
1999
- 1999-04-26 TW TW088106644A patent/TW450954B/zh not_active IP Right Cessation
- 1999-05-07 BR BR9910405-9A patent/BR9910405A/pt not_active Application Discontinuation
- 1999-05-07 DK DK99919771T patent/DK1077935T3/da active
- 1999-05-07 CA CA002327345A patent/CA2327345A1/en not_active Abandoned
- 1999-05-07 HU HU0101746A patent/HUP0101746A3/hu unknown
- 1999-05-07 EP EP99919771A patent/EP1077935B1/de not_active Expired - Lifetime
- 1999-05-07 DE DE69912419T patent/DE69912419T2/de not_active Expired - Fee Related
- 1999-05-07 IL IL13926399A patent/IL139263A0/xx not_active IP Right Cessation
- 1999-05-07 JP JP2000548303A patent/JP2002514623A/ja not_active Withdrawn
- 1999-05-07 KR KR1020007012661A patent/KR20010043546A/ko not_active Abandoned
- 1999-05-07 CN CNB998052175A patent/CN1152857C/zh not_active Expired - Fee Related
- 1999-05-07 PT PT99919771T patent/PT1077935E/pt unknown
- 1999-05-07 WO PCT/US1999/007023 patent/WO1999058499A1/en not_active Ceased
- 1999-05-07 NZ NZ508152A patent/NZ508152A/xx unknown
- 1999-05-07 AT AT99919771T patent/ATE253045T1/de not_active IP Right Cessation
- 1999-05-07 TR TR2000/03325T patent/TR200003325T2/xx unknown
- 1999-05-07 US US09/306,748 patent/US6103766A/en not_active Expired - Fee Related
- 1999-05-07 PL PL99343891A patent/PL343891A1/xx unknown
- 1999-05-07 AU AU37418/99A patent/AU752543B2/en not_active Ceased
- 1999-05-07 SK SK1624-2000A patent/SK16242000A3/sk unknown
- 1999-05-07 EA EA200001184A patent/EA002918B1/ru not_active IP Right Cessation
- 1999-05-07 ES ES99919771T patent/ES2211078T3/es not_active Expired - Lifetime
-
2000
- 2000-10-23 ZA ZA200005921A patent/ZA200005921B/en unknown
- 2000-11-13 NO NO20005732A patent/NO20005732L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200005921B (en) | 2001-11-14 |
| NO20005732D0 (no) | 2000-11-13 |
| NZ508152A (en) | 2003-03-28 |
| KR20010043546A (ko) | 2001-05-25 |
| AU3741899A (en) | 1999-11-29 |
| CN1297431A (zh) | 2001-05-30 |
| HK1036049A1 (en) | 2001-12-21 |
| TW450954B (en) | 2001-08-21 |
| CA2327345A1 (en) | 1999-11-18 |
| IL139263A0 (en) | 2001-11-25 |
| SK16242000A3 (sk) | 2001-06-11 |
| DE69912419D1 (de) | 2003-12-04 |
| HUP0101746A2 (hu) | 2002-03-28 |
| ES2211078T3 (es) | 2004-07-01 |
| JP2002514623A (ja) | 2002-05-21 |
| DK1077935T3 (da) | 2004-02-16 |
| HUP0101746A3 (en) | 2002-10-28 |
| CN1152857C (zh) | 2004-06-09 |
| US6103766A (en) | 2000-08-15 |
| DE69912419T2 (de) | 2004-07-22 |
| PL343891A1 (en) | 2001-09-10 |
| EA002918B1 (ru) | 2002-10-31 |
| TR200003325T2 (tr) | 2001-04-20 |
| BR9910405A (pt) | 2001-01-09 |
| EP1077935A1 (de) | 2001-02-28 |
| PT1077935E (pt) | 2004-03-31 |
| NO20005732L (no) | 2000-11-13 |
| EA200001184A1 (ru) | 2001-04-23 |
| AU752543B2 (en) | 2002-09-19 |
| WO1999058499A1 (en) | 1999-11-18 |
| EP1077935B1 (de) | 2003-10-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0923542T3 (da) | Arylsubstituerede cycliske aminer som selektive dopamin-D3-ligander | |
| DE69912419D1 (de) | Phenylsulfonamid-phenylethylamine nützlich als dopamin-rezeptoren | |
| FI943247A0 (fi) | Piperatsiinijohdannaisia 5-HT-reseptoriantagonisteina | |
| NO912301D0 (no) | Nye indolderivater. | |
| ES2031513T3 (es) | Quinazolindionas y piridopirimidinadionas. | |
| PE20020911A1 (es) | Derivados de indol como agonistas de 5ht2 | |
| NO973532L (no) | 2-aminoindaner som selektive dopamin D3-ligander | |
| DE60014339D1 (de) | Aryl- und heteroaryl-kondensierte aminoalkyl-imidazol-derivate: selektive modulatoren der gabaa-rezeptoren | |
| ES2128668T3 (es) | Agonistas del receptor de 5-ht4. | |
| DE60003899D1 (de) | Aryl-annellierte disubstituierte pyridine : nk3 rezeptor-liganden | |
| BR9908321A (pt) | Composto | |
| PE130999A1 (es) | 4-oxo-naftiridin-3-carboxamidas sustituidas; ligandos de receptor cerebral gaba | |
| ATE341538T1 (de) | Benzimidazolonderivate mit affinität zu serotonin-und dopaminrezeptoren | |
| PE20060632A1 (es) | Derivados de arilsulfonilestilbeno como antagonistas de los receptores 5-ht2a | |
| NZ511289A (en) | 3-tetrahydropyridin-4-yl indoles, which show high affinity for both the dopamine d2 receptor and the serotonin reuptake site, for treatment of psychotic disorders | |
| ES2182509T3 (es) | Derivados de n-ariloxietilamina para el tratamiento de la depresion. | |
| PE20040788A1 (es) | Derivados de indol con afinidad al receptor de androgeno | |
| AR058576A1 (es) | Compuestos con efectos medicinales debido a la interaccion con el receptor glucocorticoide | |
| AR029744A1 (es) | Procedimiento para preparar tioamidas ciclicas y compuestos utiles en dicho procedimiento | |
| TH50283A (th) | อนุพันธ์ 5-ฟีนิล-ไพริมิดีน |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1077935 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |