PT1077935E - Fenilsulfonamida-feniletilaminas uteis como receptores da dopamina - Google Patents

Fenilsulfonamida-feniletilaminas uteis como receptores da dopamina

Info

Publication number
PT1077935E
PT1077935E PT99919771T PT99919771T PT1077935E PT 1077935 E PT1077935 E PT 1077935E PT 99919771 T PT99919771 T PT 99919771T PT 99919771 T PT99919771 T PT 99919771T PT 1077935 E PT1077935 E PT 1077935E
Authority
PT
Portugal
Prior art keywords
phenyethylamines
phenylsulfonamide
useful
dopamine receptors
alkyl
Prior art date
Application number
PT99919771T
Other languages
English (en)
Portuguese (pt)
Inventor
Jeffrey A Leiby
Arthur Glenn Romero
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PT1077935E publication Critical patent/PT1077935E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46Y being a hydrogen or a carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT99919771T 1998-05-14 1999-05-07 Fenilsulfonamida-feniletilaminas uteis como receptores da dopamina PT1077935E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8549398P 1998-05-14 1998-05-14

Publications (1)

Publication Number Publication Date
PT1077935E true PT1077935E (pt) 2004-03-31

Family

ID=22191975

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99919771T PT1077935E (pt) 1998-05-14 1999-05-07 Fenilsulfonamida-feniletilaminas uteis como receptores da dopamina

Country Status (24)

Country Link
US (1) US6103766A (enExample)
EP (1) EP1077935B1 (enExample)
JP (1) JP2002514623A (enExample)
KR (1) KR20010043546A (enExample)
CN (1) CN1152857C (enExample)
AT (1) ATE253045T1 (enExample)
AU (1) AU752543B2 (enExample)
BR (1) BR9910405A (enExample)
CA (1) CA2327345A1 (enExample)
DE (1) DE69912419T2 (enExample)
DK (1) DK1077935T3 (enExample)
EA (1) EA002918B1 (enExample)
ES (1) ES2211078T3 (enExample)
HU (1) HUP0101746A3 (enExample)
IL (1) IL139263A0 (enExample)
NO (1) NO20005732D0 (enExample)
NZ (1) NZ508152A (enExample)
PL (1) PL343891A1 (enExample)
PT (1) PT1077935E (enExample)
SK (1) SK16242000A3 (enExample)
TR (1) TR200003325T2 (enExample)
TW (1) TW450954B (enExample)
WO (1) WO1999058499A1 (enExample)
ZA (1) ZA200005921B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT971878E (pt) * 1997-02-27 2008-07-08 Takeda Pharmaceutical Compostos de amina, sua produção e utilização como inibidores da produção de amilóide beta
JP2005508852A (ja) * 2001-05-07 2005-04-07 スミスクライン・ビーチャム・コーポレイション スルホンアミド
WO2002089785A1 (en) * 2001-05-07 2002-11-14 Smithkline Beecham Corporation Sulfonamides
ATE520659T1 (de) 2004-10-14 2011-09-15 Abbott Gmbh & Co Kg Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
CA2583918C (en) * 2004-10-14 2013-01-29 Abbott Gmbh & Co. Kg Aminoethylaromatic compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor
DE602005027382D1 (de) 2004-10-14 2011-05-19 Abbott Gmbh & Co Kg Zur behandlung von auf eine modulation des dopamin-d3-rezeptors ansprechende erkrankungen geeignete heterocyclische verbindungen
TWI400233B (zh) * 2006-04-14 2013-07-01 Abbott Gmbh & Co Kg 適用於治療對多巴胺d3受體之調節有反應的疾病之芳氧基乙胺化合物
CA2648543C (en) * 2006-04-14 2015-06-02 Abbott Gmbh & Co. Kg Aryloxyethylamine compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor
JP2009534355A (ja) 2006-04-19 2009-09-24 アボット ゲーエムベーハー ウント カンパニー カーゲー セロトニン5ht6受容体の調節に応答する障害を治療するために好適な複素環化合物
MX2008013434A (es) 2006-04-19 2009-01-26 Abbott Gmbh & Co Kg Arilsufonas heterociclicas adecuadas para tratar trastornos que responden a la modulacion del receptor de serotonina 5ht6.
WO2008026046A1 (en) * 2006-08-30 2008-03-06 Pfizer Products Inc. Morpholine d3 dopamine antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
GB9402197D0 (en) * 1994-02-04 1994-03-30 Smithkline Beecham Plc Compounds
CN1088062C (zh) * 1994-11-23 2002-07-24 纽罗根公司 某些4-氨基甲基-2-取代的咪唑衍生物2-氨基甲基-4-取代的咪唑衍生物新的一族多巴胺受体亚型特异性配体
EP0917530B1 (en) * 1996-05-11 2003-02-19 SmithKline Beecham plc Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
US5922770A (en) * 1996-07-22 1999-07-13 Novo Nordisk A/S Compounds with growth hormone releasing properties
JPH1180156A (ja) * 1997-09-04 1999-03-26 Hokuriku Seiyaku Co Ltd 1−(置換アリール)アルキル−1h−イミダゾピリジン−4−アミン誘導体

Also Published As

Publication number Publication date
HUP0101746A2 (hu) 2002-03-28
NZ508152A (en) 2003-03-28
TW450954B (en) 2001-08-21
SK16242000A3 (sk) 2001-06-11
AU752543B2 (en) 2002-09-19
NO20005732L (no) 2000-11-13
WO1999058499A1 (en) 1999-11-18
TR200003325T2 (tr) 2001-04-20
DE69912419D1 (de) 2003-12-04
PL343891A1 (en) 2001-09-10
EA200001184A1 (ru) 2001-04-23
NO20005732D0 (no) 2000-11-13
EP1077935A1 (en) 2001-02-28
KR20010043546A (ko) 2001-05-25
BR9910405A (pt) 2001-01-09
ES2211078T3 (es) 2004-07-01
EA002918B1 (ru) 2002-10-31
JP2002514623A (ja) 2002-05-21
IL139263A0 (en) 2001-11-25
HUP0101746A3 (en) 2002-10-28
CN1297431A (zh) 2001-05-30
EP1077935B1 (en) 2003-10-29
US6103766A (en) 2000-08-15
ZA200005921B (en) 2001-11-14
HK1036049A1 (en) 2001-12-21
ATE253045T1 (de) 2003-11-15
DK1077935T3 (da) 2004-02-16
DE69912419T2 (de) 2004-07-22
CA2327345A1 (en) 1999-11-18
CN1152857C (zh) 2004-06-09
AU3741899A (en) 1999-11-29

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