JP2002507576A5 - - Google Patents

Download PDF

Info

Publication number
JP2002507576A5
JP2002507576A5 JP2000537561A JP2000537561A JP2002507576A5 JP 2002507576 A5 JP2002507576 A5 JP 2002507576A5 JP 2000537561 A JP2000537561 A JP 2000537561A JP 2000537561 A JP2000537561 A JP 2000537561A JP 2002507576 A5 JP2002507576 A5 JP 2002507576A5
Authority
JP
Japan
Prior art keywords
seq
formula
peptide
fmoc
side chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000537561A
Other languages
English (en)
Japanese (ja)
Other versions
JP4602547B2 (ja
JP2002507576A (ja
Filing date
Publication date
Priority claimed from US09/045,920 external-priority patent/US6281331B1/en
Application filed filed Critical
Priority claimed from PCT/US1999/006230 external-priority patent/WO1999048513A1/en
Publication of JP2002507576A publication Critical patent/JP2002507576A/ja
Publication of JP2002507576A5 publication Critical patent/JP2002507576A5/ja
Application granted granted Critical
Publication of JP4602547B2 publication Critical patent/JP4602547B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2000537561A 1998-03-23 1999-03-22 ペプチド合成のための方法および組成物 Expired - Fee Related JP4602547B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/045,920 US6281331B1 (en) 1998-03-23 1998-03-23 Methods and compositions for peptide synthesis
US09/071,877 US6015881A (en) 1998-03-23 1998-05-01 Methods and compositions for peptide synthesis
US09/071,877 1998-05-01
US09/045,920 1998-05-01
PCT/US1999/006230 WO1999048513A1 (en) 1998-03-23 1999-03-22 Methods and compositions for peptide synthesis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009247579A Division JP4755713B2 (ja) 1998-03-23 2009-10-28 ペプチド合成のための方法および組成物

Publications (3)

Publication Number Publication Date
JP2002507576A JP2002507576A (ja) 2002-03-12
JP2002507576A5 true JP2002507576A5 (https=) 2006-06-08
JP4602547B2 JP4602547B2 (ja) 2010-12-22

Family

ID=26723345

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000537561A Expired - Fee Related JP4602547B2 (ja) 1998-03-23 1999-03-22 ペプチド合成のための方法および組成物

Country Status (13)

Country Link
EP (1) EP1071442B9 (https=)
JP (1) JP4602547B2 (https=)
CN (1) CN100383158C (https=)
AT (1) ATE299029T1 (https=)
AU (1) AU751358B2 (https=)
BR (1) BR9909018A (https=)
CA (1) CA2324348C (https=)
DE (1) DE69926061T2 (https=)
DK (1) DK1071442T3 (https=)
ES (1) ES2245505T3 (https=)
NZ (1) NZ507083A (https=)
TW (1) TWI233931B (https=)
WO (1) WO1999048513A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281331B1 (en) * 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
US6469136B1 (en) * 1999-07-07 2002-10-22 Trimeris, Inc. Methods and composition for peptide synthesis
AU2002314111A1 (en) 2001-06-15 2003-01-02 F. Hoffmann-La Roche Ag Method for the recombinant production of peptidic antiviral fusion inhibitors, and acetylation of gb41 fragments
HRP20050024A2 (en) * 2002-07-24 2006-02-28 F. Hoffmann - La Roche Ag Pegylated t20 polypeptide
ES2295961T3 (es) 2003-12-31 2008-04-16 F. Hoffmann-La Roche Ag Proceso para la sintesis peptidica utilizacndo una cantidad reducida de agente de desproteccion.
EP1701976A2 (en) * 2003-12-31 2006-09-20 F.Hoffmann-La Roche Ag Peptide synthesis and deprotection with co-solvent
ATE410437T1 (de) 2003-12-31 2008-10-15 Hoffmann La Roche Verfahren und systeme zur rückgewinnung von peptiden
JP4886702B2 (ja) * 2004-12-30 2012-02-29 エフ.ホフマン−ラ ロシュ アーゲー ペプチド中間体断片を使用するペプチドt−20の合成
US8022181B2 (en) 2006-05-03 2011-09-20 Mallinckrodt Llc Composition and method for the release of protected peptides from a resin
EP2181983A4 (en) * 2007-07-25 2013-01-02 Ajinomoto Kk METHOD FOR THE SELECTIVE REMOVAL OF A DIBENZOFULVENE DERIVATIVE
JP5473925B2 (ja) * 2007-10-27 2014-04-16 コーデン ファーマ コロラド インコーポレイテッド 固相および溶液相の組み合わせ技法を使用するインスリン分泌性ペプチドの合成
BRPI0820765A2 (pt) * 2007-12-11 2015-06-16 Hoffmann La Roche Métodos para a produção de um peptídeo insulinotrópico e peptídeos
JP5445456B2 (ja) 2008-08-06 2014-03-19 味の素株式会社 ジベンゾフルベンの除去方法
US20110288235A1 (en) * 2008-09-03 2011-11-24 Scinopharm Taiwan Ltd. Process for the Preparation of Pramlintide
WO2010028131A1 (en) * 2008-09-03 2010-03-11 Scinopharm Taiwan Ltd. Process for the preparation of pramlintide
WO2011095989A2 (en) * 2010-02-04 2011-08-11 Matrix Laboratories Ltd An improved process for the preparation of enfuvirtide
PL219569B1 (pl) * 2010-02-19 2015-05-29 Peptaderm Spółka Z Ograniczoną Odpowiedzialnością Cykliczne tetrapeptydy i ich zastosowanie
CN103374054B (zh) * 2012-04-28 2014-12-24 上海第一生化药业有限公司 一步法固相合成多肽的方法
GB201315335D0 (en) 2013-08-29 2013-10-09 Of Singapore Amino diacids containing peptide modifiers
IL295109A (en) * 2020-02-05 2022-09-01 Lilly Co Eli Resin miners in a serial peptide synthesizer
CN114315957B (zh) * 2021-12-30 2023-07-07 深圳瑞德林生物技术有限公司 一种多肽的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0269712A4 (en) * 1986-06-12 1990-06-26 Biogen Nv PEPTIDES INVOLVED IN THE PATHOGENESIS OF A HIV TYPE INFECTION.
US4787222A (en) * 1986-11-24 1988-11-29 Novatek Medical Inc. Combination lock for blood identification system
US5444044A (en) * 1992-03-26 1995-08-22 New York Blood Center Synthetic polypeptides as inhibitors of HIV-1
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
EP0708659A4 (en) * 1993-06-07 2000-08-23 Genentech Inc HIV ENVELOPE POLYPEPTIDES
US6479055B1 (en) * 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
DE69426725T2 (de) * 1993-09-11 2001-09-06 Polimun Scientific Immunbiologische Forschungsgesellschaft Mbh, Wien Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren
AU722895B2 (en) * 1996-02-09 2000-08-10 F. Hoffmann-La Roche Ag Synthesis of VIP analog

Similar Documents

Publication Publication Date Title
JP2002507576A5 (https=)
JP2003530311A5 (https=)
Sieber A new acid-labile anchor group for the solid-phase synthesis of C-terminal peptide amides by the Fmoc method.
TW201305186A (zh) 用於製造地蓋瑞利(degarelix)及其中間產物的方法(二)
Carpino et al. Protected amino acid chlorides vs protected amino acid fluorides: reactivity comparisons
JPH02221294A (ja) ペプチド合成法
JPH11507911A (ja) 合成用の改良されたシントンと、緩やかな条件下でのペプチド核酸の保護解除方法
CA2324348A1 (en) Methods and compositions for peptide synthesis
CN109575109B (zh) 片段缩合制备地加瑞克的方法
JP5138845B2 (ja) 固相中でのペプチド合成法
HU185321B (en) Process for preparing pharmacologically active ancephaline analogues
JP2888991B2 (ja) Nα−2−(4−ニトロフェニルスルフォニル)エトキシカルボニル−アミノ酸
EP0274999A2 (en) Resin support for solid phase peptide synthesis
Nishiuchi et al. Nin-Cyclohexyloxycarbonyl group as a new protecting group for tryptophan
Limal et al. Solid-phase synthesis of N, N′-unsymmetrically substituted ureas: application to the synthesis of carbaza peptides
KR20210046730A (ko) Wnt 헥사펩티드에 대한 용액상 경로
HU185229B (en) Process for preparing pharmaceutically active peptides and acetates thereof
KR100203548B1 (ko) 고체상 합성에 의한 펩티드의 제조방법
JP2005516962A5 (https=)
Paris et al. Post-synthesis modification of aspartyl or glutamyl residue side-chains on solid support
EP1630169B1 (en) Intermediates for LHRH antagonist synthesis, process for their production, and process for LHRH antagonist production
JPS59101451A (ja) 薬理学的に活性なペプチド
US4764594A (en) Resin support for solid phase peptide synthesis
WO1990005738A1 (en) Trialkysilyl esters of amino acids and their use in the synthesis of peptides
CA1335403C (en) Process and intermediates for lh-rh peptides