JP2002505071A - 特異的かつ高感度な核酸検出方法 - Google Patents
特異的かつ高感度な核酸検出方法Info
- Publication number
- JP2002505071A JP2002505071A JP2000519105A JP2000519105A JP2002505071A JP 2002505071 A JP2002505071 A JP 2002505071A JP 2000519105 A JP2000519105 A JP 2000519105A JP 2000519105 A JP2000519105 A JP 2000519105A JP 2002505071 A JP2002505071 A JP 2002505071A
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- nucleic acid
- sequence
- binding
- probe
- detected
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- 238000005457 optimization Methods 0.000 description 1
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- 102000040430 polynucleotide Human genes 0.000 description 1
- 108091033319 polynucleotide Proteins 0.000 description 1
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- 239000013641 positive control Substances 0.000 description 1
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- 230000037452 priming Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 150000003230 pyrimidines Chemical class 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 150000004053 quinones Chemical class 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
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- 238000011069 regeneration method Methods 0.000 description 1
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- 238000010839 reverse transcription Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000005464 sample preparation method Methods 0.000 description 1
- 238000010517 secondary reaction Methods 0.000 description 1
- 238000011896 sensitive detection Methods 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19748690A DE19748690A1 (de) | 1997-11-04 | 1997-11-04 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| DE19748690.8 | 1997-11-04 | ||
| DE19814001.0 | 1998-03-28 | ||
| DE19814001A DE19814001A1 (de) | 1998-03-28 | 1998-03-28 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| DE19814828A DE19814828A1 (de) | 1998-04-02 | 1998-04-02 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| DE19814828.3 | 1998-04-02 | ||
| PCT/EP1998/006961 WO1999023250A2 (de) | 1997-11-04 | 1998-11-03 | Spezifisches und sensitives nukleinsäurenachweisverfahren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002505071A true JP2002505071A (ja) | 2002-02-19 |
| JP2002505071A5 JP2002505071A5 (https=) | 2006-01-05 |
Family
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|---|---|---|---|
| JP2000519105A Pending JP2002505071A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
| JP2000519104A Pending JP2002509694A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
| JP2000519599A Pending JP2001521765A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
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| JP2000519104A Pending JP2002509694A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
| JP2000519599A Pending JP2001521765A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7105318B2 (https=) |
| EP (3) | EP1029083A2 (https=) |
| JP (3) | JP2002505071A (https=) |
| AU (3) | AU2152099A (https=) |
| CA (3) | CA2308762A1 (https=) |
| WO (3) | WO1999023250A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022230214A1 (ja) * | 2021-04-28 | 2022-11-03 | バイオニクス株式会社 | 光学測定装置 |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| CA2313641A1 (en) * | 1997-12-12 | 1999-06-24 | Digene Corporation | Universal collection medium |
| WO1999049293A2 (en) | 1998-03-24 | 1999-09-30 | Boston Probes, Inc. | Methods, kits and compositions pertaining to detection complexes |
| US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| US7601497B2 (en) * | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7807802B2 (en) | 2002-11-12 | 2010-10-05 | Abbott Lab | Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae |
| EP3095873B1 (en) | 2006-12-21 | 2018-04-18 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| US8617816B2 (en) * | 2007-03-16 | 2013-12-31 | 454 Life Sciences, A Roche Company | System and method for detection of HIV drug resistant variants |
| GB0714389D0 (en) | 2007-07-21 | 2007-09-05 | Barry Callebaut Ag | Process and product |
| CA2726396C (en) * | 2008-04-17 | 2019-03-19 | Qiagen Gaithersburg, Inc. | Compositions, methods, and kits using synthetic probes for determining the presence of a target nucleic acid |
| TWI419974B (zh) | 2008-10-27 | 2013-12-21 | Qiagen Gaithersburg Inc | 於自動平台上之快速結果雜交捕捉法 |
| ES2644516T3 (es) * | 2009-01-28 | 2017-11-29 | Qiagen Gaithersburg, Inc. | Método y ensayo de preparación de muestras de gran volumen específico de secuencia |
| WO2010127228A1 (en) * | 2009-05-01 | 2010-11-04 | Qiagen Gaithersburg, Inc. | A non-target amplification method for detection of rna splice-forms in a sample |
| US8512955B2 (en) | 2009-07-01 | 2013-08-20 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| JP5826752B2 (ja) | 2009-09-14 | 2015-12-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法 |
| CA2787924A1 (en) | 2010-01-29 | 2011-08-04 | Qiagen Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| JP2013517803A (ja) | 2010-01-29 | 2013-05-20 | キアジェン ゲイサーズバーグ インコーポレイテッド | サンプル中のｈｐｖの存在を決定および確認する方法 |
| EP2572001A2 (en) | 2010-05-19 | 2013-03-27 | QIAGEN Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| JP6153866B2 (ja) | 2010-05-25 | 2017-06-28 | キアゲン ガイサーズバーグ アイエヌシー． | 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ |
| WO2012116220A2 (en) | 2011-02-24 | 2012-08-30 | Qiagen Gaithersburg, Inc. | Materials and methods for detection of hpv nucleic acid |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1190838A (en) * | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| US5200313A (en) | 1983-08-05 | 1993-04-06 | Miles Inc. | Nucleic acid hybridization assay employing detectable anti-hybrid antibodies |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| AU606043B2 (en) * | 1985-03-28 | 1991-01-31 | F. Hoffmann-La Roche Ag | Detection of viruses by amplification and hybridization |
| ES286841Y (es) | 1985-05-20 | 1988-10-01 | Vileda Gmbh | Dispositivo de acoplamiento de un mango a un util de limpieza |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5639871A (en) * | 1988-09-09 | 1997-06-17 | Roche Molecular Systems, Inc. | Detection of human papillomavirus by the polymerase chain reaction |
| WO1991001384A1 (en) | 1989-07-11 | 1991-02-07 | Gen-Probe, Incorporated | Nucleic acid sequence amplification methods utilizing a transcription complex |
| NL9000134A (nl) * | 1990-01-19 | 1991-08-16 | Stichting Res Fonds Pathologie | Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr. |
| US5453355A (en) * | 1990-01-26 | 1995-09-26 | Abbott Laboratories | Oligonucleotides and methods for the detection of Neisseria gonorrhoeae |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| PL169880B1 (pl) * | 1991-05-08 | 1996-09-30 | Chiron Corp | Sposób wytwarzania produktu hybrydyzacji z kwasem nukleinowym wirusa zapalenia watroby C PL PL PL |
| ES2111589T3 (es) | 1991-08-27 | 1998-03-16 | Hoffmann La Roche | Metodos y reactivos para la deteccion de la hepatitis c. |
| JPH05308999A (ja) * | 1992-05-08 | 1993-11-22 | Sumitomo Metal Ind Ltd | Ｂ型肝炎ウイルスｐｒｅ−Ｃ変異の判定法 |
| WO1994003635A1 (en) | 1992-08-04 | 1994-02-17 | Institute Of Molecular Biology & Biotechnology | Rapid amplification and detection of nucleic acids |
| US5605798A (en) * | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| EP0785996A1 (en) * | 1993-07-13 | 1997-07-30 | Abbott Laboratories | Nucleotide sequences and process for amplifying and detection of hepatitis b virus |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| AT406019B (de) * | 1995-05-08 | 2000-01-25 | Immuno Ag | Verfahren zur herstellung eines arzneimittels enthaltend ein oder mehrere plasmaderivate |
| US5882857A (en) | 1995-06-07 | 1999-03-16 | Behringwerke Ag | Internal positive controls for nucleic acid amplification |
| JP4540754B2 (ja) | 1996-06-04 | 2010-09-08 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | Ｐｃｒ中のハイブリダイゼーションのモニタリング |
| US5858671A (en) | 1996-11-01 | 1999-01-12 | The University Of Iowa Research Foundation | Iterative and regenerative DNA sequencing method |
| US6333179B1 (en) * | 1997-06-20 | 2001-12-25 | Affymetrix, Inc. | Methods and compositions for multiplex amplification of nucleic acids |
| CA2318880C (en) | 1998-02-04 | 2010-07-27 | Applied Biosystems, Llc | Determination of a genotype of an amplification product at multiple allelic sites |
| US5948648A (en) | 1998-05-29 | 1999-09-07 | Khan; Shaheer H. | Nucleotide compounds including a rigid linker |
-
1998
- 1998-11-03 JP JP2000519105A patent/JP2002505071A/ja active Pending
- 1998-11-03 CA CA002308762A patent/CA2308762A1/en not_active Abandoned
- 1998-11-03 CA CA002308368A patent/CA2308368C/en not_active Expired - Fee Related
- 1998-11-03 AU AU21520/99A patent/AU2152099A/en not_active Abandoned
- 1998-11-03 AU AU12320/99A patent/AU1232099A/en not_active Abandoned
- 1998-11-03 EP EP98965652A patent/EP1029083A2/de not_active Ceased
- 1998-11-03 JP JP2000519104A patent/JP2002509694A/ja active Pending
- 1998-11-03 JP JP2000519599A patent/JP2001521765A/ja active Pending
- 1998-11-03 WO PCT/EP1998/006961 patent/WO1999023250A2/de not_active Ceased
- 1998-11-03 EP EP98965653A patent/EP1029084A2/de not_active Withdrawn
- 1998-11-03 WO PCT/EP1998/006952 patent/WO1999023249A2/de not_active Ceased
- 1998-11-03 EP EP98955529A patent/EP1029077A2/de not_active Ceased
- 1998-11-03 WO PCT/EP1998/006951 patent/WO1999024606A2/de not_active Ceased
- 1998-11-03 CA CA002312779A patent/CA2312779A1/en not_active Abandoned
- 1998-11-03 AU AU21521/99A patent/AU741141B2/en not_active Ceased
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2002
- 2002-12-17 US US10/322,138 patent/US7105318B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022230214A1 (ja) * | 2021-04-28 | 2022-11-03 | バイオニクス株式会社 | 光学測定装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1029077A2 (de) | 2000-08-23 |
| WO1999024606A3 (de) | 1999-07-22 |
| US20030175765A1 (en) | 2003-09-18 |
| US7105318B2 (en) | 2006-09-12 |
| CA2308762A1 (en) | 1999-05-14 |
| WO1999023249A3 (de) | 1999-09-10 |
| AU741141B2 (en) | 2001-11-22 |
| AU2152199A (en) | 1999-05-24 |
| WO1999023249A2 (de) | 1999-05-14 |
| WO1999023250A3 (de) | 1999-07-22 |
| AU2152099A (en) | 1999-05-31 |
| WO1999023250A2 (de) | 1999-05-14 |
| AU1232099A (en) | 1999-05-24 |
| CA2308368A1 (en) | 1999-05-14 |
| EP1029084A2 (de) | 2000-08-23 |
| EP1029083A2 (de) | 2000-08-23 |
| JP2001521765A (ja) | 2001-11-13 |
| CA2312779A1 (en) | 1999-05-20 |
| WO1999024606A2 (de) | 1999-05-20 |
| JP2002509694A (ja) | 2002-04-02 |
| CA2308368C (en) | 2009-01-20 |
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