JP2002097158A5 - - Google Patents
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- Publication number
- JP2002097158A5 JP2002097158A5 JP2001216132A JP2001216132A JP2002097158A5 JP 2002097158 A5 JP2002097158 A5 JP 2002097158A5 JP 2001216132 A JP2001216132 A JP 2001216132A JP 2001216132 A JP2001216132 A JP 2001216132A JP 2002097158 A5 JP2002097158 A5 JP 2002097158A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- substituted
- alkyl
- phenyl
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 14
- 125000004433 nitrogen atom Chemical group N* 0.000 description 12
- 125000000217 alkyl group Chemical group 0.000 description 11
- 229910052757 nitrogen Inorganic materials 0.000 description 10
- 125000003545 alkoxy group Chemical group 0.000 description 8
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 7
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 description 4
- 125000003341 7 membered heterocyclic group Chemical group 0.000 description 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 4
- 229910052801 chlorine Inorganic materials 0.000 description 4
- 125000001309 chloro group Chemical group Cl* 0.000 description 4
- 231100000252 nontoxic Toxicity 0.000 description 4
- 230000003000 nontoxic effect Effects 0.000 description 4
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 description 2
- YCYMCMYLORLIJX-UHFFFAOYSA-N 2-propyloctanoic acid Chemical compound CCCCCCC(C(O)=O)CCC YCYMCMYLORLIJX-UHFFFAOYSA-N 0.000 description 2
- 208000018737 Parkinson disease Diseases 0.000 description 2
- 206010034010 Parkinsonism Diseases 0.000 description 2
- 125000003342 alkenyl group Chemical group 0.000 description 2
- 125000004414 alkyl thio group Chemical group 0.000 description 2
- 125000001118 alkylidene group Chemical group 0.000 description 2
- 125000000539 amino acid group Chemical group 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 125000000753 cycloalkyl group Chemical group 0.000 description 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 description 2
- 125000001153 fluoro group Chemical group F* 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- 125000004430 oxygen atom Chemical group O* 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- 206010052904 Musculoskeletal stiffness Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 229960003638 dopamine Drugs 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001216132A JP4706950B2 (ja) | 2000-07-18 | 2001-07-17 | アストロサイト機能改善剤を有効成分として含有するパーキンソン病治療剤 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000216763 | 2000-07-18 | ||
| JP2000216763 | 2000-07-18 | ||
| JP2000-216763 | 2000-07-18 | ||
| JP2001216132A JP4706950B2 (ja) | 2000-07-18 | 2001-07-17 | アストロサイト機能改善剤を有効成分として含有するパーキンソン病治療剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002097158A JP2002097158A (ja) | 2002-04-02 |
| JP2002097158A5 true JP2002097158A5 (enExample) | 2008-04-10 |
| JP4706950B2 JP4706950B2 (ja) | 2011-06-22 |
Family
ID=26596198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001216132A Expired - Fee Related JP4706950B2 (ja) | 2000-07-18 | 2001-07-17 | アストロサイト機能改善剤を有効成分として含有するパーキンソン病治療剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4706950B2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8569058B2 (en) | 2003-10-03 | 2013-10-29 | Ono Pharmaceutical Co., Ltd. | Nerve regeneration promoters |
| JP5485497B2 (ja) * | 2003-10-03 | 2014-05-07 | 小野薬品工業株式会社 | 神経変性疾患の予防および／または治療方法 |
| WO2005032536A1 (ja) * | 2003-10-03 | 2005-04-14 | Ono Pharmaceutical Co., Ltd. | (２ｒ)−２−プロピルオクタン酸を有効成分とする薬剤 |
| EP1669066A4 (en) * | 2003-10-03 | 2009-04-29 | Ono Pharmaceutical Co | TRANSFUSION PREPARATION CONTAINING (2R) -2-PROPYLOCTANOIC ACID AS ACTIVE INGREDIENT |
| TW200613009A (en) * | 2004-06-11 | 2006-05-01 | Ono Pharmaceutical Co | Capsule having chewing stability |
| WO2006043532A1 (ja) * | 2004-10-19 | 2006-04-27 | Ono Pharmaceutical Co., Ltd. | パーキンソン病治療剤 |
| JP5195418B2 (ja) * | 2006-03-09 | 2013-05-08 | 小野薬品工業株式会社 | 機能性脳疾患治療剤 |
| US20110112010A1 (en) * | 2008-02-15 | 2011-05-12 | The Government of the United States of America, as represented by The National Institutes of Health | Octanoic acid formulations and methods of treatment using the same |
| GB201020133D0 (en) * | 2010-11-26 | 2011-01-12 | Royal Holloway & Bedford New College | Therapeutic use of compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE163006T1 (de) * | 1993-06-01 | 1998-02-15 | Ono Pharmaceutical Co | Pentansäurederivate |
-
2001
- 2001-07-17 JP JP2001216132A patent/JP4706950B2/ja not_active Expired - Fee Related
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