JP2002508352A5 - ４(３)置換−４(３)−アミノメチル−（チオ）ピラン又はピペリジン誘導体（＝ガバペンチン類似体） - Google Patents

４(３)置換−４(３)−アミノメチル−（チオ）ピラン又はピペリジン誘導体（＝ガバペンチン類似体） Download PDF

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Publication number
JP2002508352A5
JP2002508352A5 JP2000538984A JP2000538984A JP2002508352A5 JP 2002508352 A5 JP2002508352 A5 JP 2002508352A5 JP 2000538984 A JP2000538984 A JP 2000538984A JP 2000538984 A JP2000538984 A JP 2000538984A JP 2002508352 A5 JP2002508352 A5 JP 2002508352A5
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Japan
Prior art keywords
pyran
aminomethyl
thio
substituted
piperidine derivative
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Abandoned
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JP2000538984A
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JP2002508352A (ja
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Priority claimed from PCT/US1998/023991 external-priority patent/WO1999031057A1/en
Publication of JP2002508352A publication Critical patent/JP2002508352A/ja
Publication of JP2002508352A5 publication Critical patent/JP2002508352A5/ja
Abandoned legal-status Critical Current

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【特許請求の範囲】
【請求項１】 下記式：
【化２９】
Figure 2002508352
［式中、ｎは０〜２の整数であり；
Ｒは下記：
【化３０】
Figure 2002508352
から選択される複素環であり；
Ｘは−Ｏ−、−Ｓ−、−Ｓ(Ｏ)−、−Ｓ(Ｏ)2−またはＮＲ′1であり、ここでＲ′1は水素、炭素原子１〜６個の直鎖または分枝鎖のアルキル、ベンジル、−Ｃ(Ｏ)Ｒ′2（た
だしＲ′2は炭素原子１〜６個の直鎖または分枝鎖のアルキル、ベンジルまたはフェニルである）、または、−Ｃ(Ｏ)2Ｒ′3（ただしＲ′3は炭素原子１〜６個の直鎖または分枝鎖のアルキルまたはベンジルである）であり、ここでベンジルまたはフェニル基は未置換であるか、ハロゲン、トリフルオロメチルおよびニトロから選択される置換基１〜３個で置換されることができる］の化合物または製薬上許容しうるその塩。
JP2000538984A 1997-12-16 1998-11-10 ４（３）置換−４（３）−アミノメチル−（チオ）ピラン又はピペリジン誘導体（＝ガバペンチン類似体）、それらの製法および神経病理学的疾患の治療における使用 Abandoned JP2002508352A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6977397P 1997-12-16 1997-12-16
US60/069,773 1997-12-16
US10490498P 1998-10-20 1998-10-20
US60/104,904 1998-10-20
PCT/US1998/023991 WO1999031057A1 (en) 1997-12-16 1998-11-10 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders

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JP2002508352A JP2002508352A (ja) 2002-03-19
JP2002508352A5 true JP2002508352A5 (ja) 2006-01-05

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JP2000538984A Abandoned JP2002508352A (ja) 1997-12-16 1998-11-10 ４（３）置換−４（３）−アミノメチル−（チオ）ピラン又はピペリジン誘導体（＝ガバペンチン類似体）、それらの製法および神経病理学的疾患の治療における使用

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US (1) US6545022B1 (ja)
EP (1) EP1045834A1 (ja)
JP (1) JP2002508352A (ja)
KR (1) KR20010033153A (ja)
CN (1) CN1279667A (ja)
AU (1) AU759392B2 (ja)
BR (1) BR9814287A (ja)
CA (1) CA2304967C (ja)
HU (1) HUP0100069A3 (ja)
IL (1) IL135315A0 (ja)
IS (1) IS5434A (ja)
NO (1) NO20003038D0 (ja)
NZ (1) NZ503980A (ja)
PL (1) PL341231A1 (ja)
TR (1) TR200001800T2 (ja)
WO (1) WO1999031057A1 (ja)

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