MXPA05009504A - Derivados de (-aminoacidos sustituidos con tetrazol y oxadiazolona. - Google Patents

Derivados de (-aminoacidos sustituidos con tetrazol y oxadiazolona.

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Publication number
MXPA05009504A
MXPA05009504A MXPA05009504A MXPA05009504A MXPA05009504A MX PA05009504 A MXPA05009504 A MX PA05009504A MX PA05009504 A MXPA05009504 A MX PA05009504A MX PA05009504 A MXPA05009504 A MX PA05009504A MX PA05009504 A MXPA05009504 A MX PA05009504A
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Mexico
Prior art keywords
tetrazole
oxadiazolone
amino acid
acid derivatives
substituted beta
Prior art date
Application number
MXPA05009504A
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English (en)
Inventor
Zhijian Zhu
Original Assignee
Warner Lambert Co
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Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MXPA05009504A publication Critical patent/MXPA05009504A/es

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    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical

Abstract

Esta invencion se refiere a derivados tetrazol y oxazolidinona (-aminoacidos novedosos de la formula (ver formulas 1, 2) en la que G es (ver formula) en las que de R1 a R4 se definen como en la memoria descriptiva, las composiciones farmaceuticas que los contienen y su uso para el tratamiento de diversos trastornos del sistema nervioso central y otros trastornos; los derivados de ciclopropil (-aminoacidos de esta invencion presentan actividad como ligandos alfa2delta (ligandos (2d); tales compuestos tienen afinidad por la subunidad (2dde un canal de calcio.
MXPA05009504A 2003-03-07 2004-02-23 Derivados de (-aminoacidos sustituidos con tetrazol y oxadiazolona. MXPA05009504A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45287103P 2003-03-07 2003-03-07
PCT/IB2004/000510 WO2004078734A1 (en) 2003-03-07 2004-02-23 TETRAZOLE AND OXADIAZOLONE SUBSTITUTED β-AMINO ACID DERIVATIVES

Publications (1)

Publication Number Publication Date
MXPA05009504A true MXPA05009504A (es) 2005-10-18

Family

ID=32962749

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009504A MXPA05009504A (es) 2003-03-07 2004-02-23 Derivados de (-aminoacidos sustituidos con tetrazol y oxadiazolona.

Country Status (7)

Country Link
US (1) US7250433B2 (es)
EP (1) EP1603890A1 (es)
JP (1) JP2006519831A (es)
BR (1) BRPI0408110A (es)
CA (1) CA2518218A1 (es)
MX (1) MXPA05009504A (es)
WO (1) WO2004078734A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070066591A1 (en) * 2003-05-14 2007-03-22 Xiangping Qian Compounds, compositions, and methods
GB0521743D0 (en) * 2005-10-25 2005-11-30 Novartis Ag Organic compounds
JP6185489B2 (ja) 2012-02-09 2017-08-23 ノーバス・インターナショナル・インコーポレイテッドＮｏｖｕｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ，Ｉｎｃ． 機能性ポリマー組成物
CA2878617A1 (en) 2012-07-12 2014-01-16 Houston Stephen Smith Matrix and layer compositions for protection of bioactives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
US6197819B1 (en) * 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
AU8668598A (en) 1997-08-20 1999-03-08 University Of Oklahoma, The Gaba analogs to prevent and treat gastrointestinal damage
PT1047678E (pt) * 1997-12-16 2004-12-31 Warner Lambert Co Derivados do 1-aminometil-cicloalcano substituido em 1 (=analogos da gabapentina) sua preparacao e sua utilizacao no tratamento de disturbios neurologicos
IL135315A0 (en) * 1997-12-16 2001-05-20 Warner Lambert Co 4(3)-substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (gabapentin analogues), their preparation and their use in the treatment of neurological disorders
CA2304965C (en) * 1997-12-16 2007-08-21 Warner-Lambert Company ((cyclo)alkyl substituted)-gamma-aminobutyric acid derivatives (=gaba analogues), their preparation and their use in the treatment of neurological disorders
AU757445B2 (en) 1998-05-26 2003-02-20 Warner-Lambert Company Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel
ATE280154T1 (de) 1998-09-14 2004-11-15 Warner Lambert Co Verzweigte alkylpyrrolidin-3-carbonsäuren
EP1469841A1 (en) 2002-01-31 2004-10-27 Warner-Lambert Company Alpha 2 delta ligands to treat tinnitus

Also Published As

Publication number Publication date
BRPI0408110A (pt) 2006-03-01
US20050014804A1 (en) 2005-01-20
EP1603890A1 (en) 2005-12-14
WO2004078734A1 (en) 2004-09-16
CA2518218A1 (en) 2004-09-16
US7250433B2 (en) 2007-07-31
WO2004078734A8 (en) 2005-12-15
JP2006519831A (ja) 2006-08-31

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