JP2002332234A5 - - Google Patents

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Publication number
JP2002332234A5
JP2002332234A5 JP2002088076A JP2002088076A JP2002332234A5 JP 2002332234 A5 JP2002332234 A5 JP 2002332234A5 JP 2002088076 A JP2002088076 A JP 2002088076A JP 2002088076 A JP2002088076 A JP 2002088076A JP 2002332234 A5 JP2002332234 A5 JP 2002332234A5
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JP
Japan
Prior art keywords
formula
formulation
voriconazole
present
cyclodextrin derivative
Prior art date
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Application number
JP2002088076A
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English (en)
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JP5089004B2 (ja
JP2002332234A (ja
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Publication date
Priority claimed from GBGB9713149.4A external-priority patent/GB9713149D0/en
Application filed filed Critical
Publication of JP2002332234A publication Critical patent/JP2002332234A/ja
Publication of JP2002332234A5 publication Critical patent/JP2002332234A5/ja
Application granted granted Critical
Publication of JP5089004B2 publication Critical patent/JP5089004B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Description

【特許請求の範囲】
【請求項１】 ボリコナゾールと、式I；
【化１】
Figure 2002332234
［式中、Ｒ1a-g、Ｒ2a-g、及びＲ3a-gは独立的にＯＨ又はＯ（ＣＨ2）4ＳＯ3Ｈを表す；但し、Ｒ1a-gの少なくとも１つはＯ（ＣＨ2）4ＳＯ3Ｈを表す］で示されるシクロデキストリン誘導体又はその製薬的に許容される塩とを含む薬剤製剤であって、
当該式Ｉのシクロデキストリン誘導体が１：１から１：１０までのボリコナゾール：シクロデキストリン誘導体のモル比率で存在し、および、
当該製剤は凍結乾燥されている、
当該製剤。
【請求項２】 式Ｉの分子当りのＯ（ＣＨ2）4ＳＯ3Ｈ基の平均数は６．１〜６．９の範囲内である、請求項１記載の製剤。
【請求項３】 存在する各Ｏ（ＣＨ2）4ＳＯ3Ｈがアルカリ金属塩の形状である、請求項１又は請求項２に記載の製剤。
JP2002088076A 1997-06-21 2002-03-27 ボリコナゾールを含有する薬剤製剤 Expired - Lifetime JP5089004B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9713149.4 1997-06-21
GBGB9713149.4A GB9713149D0 (en) 1997-06-21 1997-06-21 Pharmaceutical formulations

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP11503686A Division JP2000513029A (ja) 1997-06-21 1998-06-02 ボリコナゾールを含有する薬剤製剤

Publications (3)

Publication Number Publication Date
JP2002332234A JP2002332234A (ja) 2002-11-22
JP2002332234A5 true JP2002332234A5 (ja) 2008-05-22
JP5089004B2 JP5089004B2 (ja) 2012-12-05

Family

ID=10814734

Family Applications (2)

Application Number Title Priority Date Filing Date
JP11503686A Withdrawn JP2000513029A (ja) 1997-06-21 1998-06-02 ボリコナゾールを含有する薬剤製剤
JP2002088076A Expired - Lifetime JP5089004B2 (ja) 1997-06-21 2002-03-27 ボリコナゾールを含有する薬剤製剤

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP11503686A Withdrawn JP2000513029A (ja) 1997-06-21 1998-06-02 ボリコナゾールを含有する薬剤製剤

Country Status (48)

Country Link
US (1) US6632803B1 (ja)
EP (1) EP1001813B8 (ja)
JP (2) JP2000513029A (ja)
KR (1) KR100372988B1 (ja)
CN (1) CN1125653C (ja)
AP (1) AP912A (ja)
AR (1) AR015900A1 (ja)
AT (1) ATE238812T1 (ja)
AU (1) AU724799B2 (ja)
BG (1) BG64584B1 (ja)
BR (1) BRPI9809468B8 (ja)
CA (1) CA2295035C (ja)
CO (1) CO4940450A1 (ja)
CZ (1) CZ289570B6 (ja)
DE (1) DE69814091T2 (ja)
DK (1) DK1001813T3 (ja)
DZ (1) DZ2523A1 (ja)
EA (1) EA001924B1 (ja)
EG (1) EG23910A (ja)
ES (1) ES2195355T3 (ja)
GB (1) GB9713149D0 (ja)
HK (1) HK1027966A1 (ja)
HR (1) HRP980341B1 (ja)
HU (1) HU228338B1 (ja)
ID (1) ID22939A (ja)
IL (1) IL132918A (ja)
IS (1) IS2004B (ja)
MA (1) MA26508A1 (ja)
ME (1) ME00907B (ja)
MY (1) MY118151A (ja)
NO (1) NO313125B1 (ja)
NZ (1) NZ501066A (ja)
OA (1) OA11232A (ja)
PA (1) PA8453201A1 (ja)
PE (1) PE84899A1 (ja)
PL (1) PL191295B1 (ja)
PT (1) PT1001813E (ja)
RS (1) RS49633B (ja)
SA (1) SA98190159B1 (ja)
SI (1) SI1001813T1 (ja)
SK (1) SK282946B6 (ja)
TN (1) TNSN98090A1 (ja)
TR (1) TR199903191T2 (ja)
TW (1) TW406023B (ja)
UA (1) UA57083C2 (ja)
UY (1) UY25055A1 (ja)
WO (1) WO1998058677A1 (ja)
ZA (1) ZA985364B (ja)

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PE20020578A1 (es) 2000-10-10 2002-08-14 Upjohn Co Una composicion de antibiotico topico para el tratamiento de infecciones oculares
SI1542668T1 (sl) 2002-08-20 2009-08-31 Bristol Myers Squibb Co Aripiprazol sestavljena formulacija in postopek
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CA2548491A1 (en) * 2003-12-08 2005-06-23 The Arizona Board Of Regents On Behalf Of The University Of Arizona Synergistic anti-cancer compositions
WO2006004795A2 (en) 2004-06-25 2006-01-12 The Johns Hopkins University Angiogenesis inhibitors
US20100204178A1 (en) 2006-10-02 2010-08-12 James Cloyd Novel parenteral carbamazepine formulation
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AR061889A1 (es) 2006-07-13 2008-10-01 Medichem Sa Proceso mejorado para la preparacion de voriconazol
CN1919846B (zh) * 2006-09-14 2013-01-02 大道隆达（北京）医药科技发展有限公司 伏立康唑及其药用盐、中间体的一种新定向合成制备方法
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US20110224232A1 (en) * 2008-05-06 2011-09-15 Board Of Regents, The University Of Texas System Treatment of Pulmonary Fungal Infection With Voriconazole via Inhalation
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CN101390825B (zh) * 2008-10-01 2010-12-29 山东省眼科研究所 一种伏立康唑眼内释药系统
EP3090737A1 (en) 2008-10-21 2016-11-09 Onyx Therapeutics, Inc. Combination therapy with peptide epoxyketones
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PL2720723T3 (pl) 2011-06-15 2018-10-31 Synthon Bv Stabilizowana kompozycja worykonazolu
EP2561863A1 (en) 2011-08-22 2013-02-27 Farmaprojects, S.A.U. Pharmaceutical compositions comprising voriconazole
WO2013103924A2 (en) * 2012-01-05 2013-07-11 Guilford Frederick Timothy Liposomally encapsulated reduced glutathione for management of cancer, including with other pharmaceutical compositions
US8853248B2 (en) 2012-04-05 2014-10-07 Hubert Maehr (1,2,3-triazolyl)sulfonyl derivatives
KR20190137963A (ko) 2012-05-08 2019-12-11 오닉스 세라퓨틱스, 인크. 펩티드 프로테아좀 억제제 제제화를 위한 사이클로덱스트린 복합체화 방법
US20150133472A1 (en) 2012-05-11 2015-05-14 Cipla Limited Pharmaceutical composition
BR112015016331B1 (pt) 2013-01-11 2020-05-12 Xellia Pharmaceuticals Aps Formulação farmacêutica estabilizada e método de estabilização de uma composição compreendendo voriconazol
EP2968595A2 (en) 2013-03-14 2016-01-20 Fresenius Kabi USA LLC Voriconazole formulations
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CN116570558B (zh) * 2023-06-21 2023-12-26 广州仁恒医药科技股份有限公司 一种伏立康唑眼用纳米缓释组合物及其制备方法和应用

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