JP2001261662A5 - - Google Patents

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Publication number
JP2001261662A5
JP2001261662A5 JP2000356303A JP2000356303A JP2001261662A5 JP 2001261662 A5 JP2001261662 A5 JP 2001261662A5 JP 2000356303 A JP2000356303 A JP 2000356303A JP 2000356303 A JP2000356303 A JP 2000356303A JP 2001261662 A5 JP2001261662 A5 JP 2001261662A5
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JP
Japan
Prior art keywords
compound represented
formula
following formula
same
pear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000356303A
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English (en)
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JP4316787B2 (ja
JP2001261662A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from JP2000356303A external-priority patent/JP4316787B2/ja
Priority to JP2000356303A priority Critical patent/JP4316787B2/ja
Priority to KR1020010000631A priority patent/KR20010070442A/ko
Priority to GB0100433A priority patent/GB2359082B/en
Priority to FR0100207A priority patent/FR2804681B1/fr
Priority to DE10100772A priority patent/DE10100772B4/de
Priority to ES200100058A priority patent/ES2187261B2/es
Priority to US09/756,701 priority patent/US6414001B2/en
Priority to IT2001MI000042A priority patent/ITMI20010042A1/it
Priority to CNB011047011A priority patent/CN1227231C/zh
Publication of JP2001261662A publication Critical patent/JP2001261662A/ja
Publication of JP2001261662A5 publication Critical patent/JP2001261662A5/ja
Publication of JP4316787B2 publication Critical patent/JP4316787B2/ja
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Claims (1)

  1. 次式：
    Figure 2001261662
    （式中、Ｒ2は前記と同じ）
    で示される化合物を還元して次式：
    Figure 2001261662
    （式中、Ｒ2は前記と同じ）
    で示される化合物とした後、メチルオキザレートを反応させて次式：
    Figure 2001261662
    で示される化合物となし、その後加水分解することを特徴とする一般式（Ｉ）で示される化合物〔但し、式中Ａは−Ｏ−、Ｒ2は前記と同じ、Ｒ1は次式：
    Figure 2001261662
    で示される基である。〕の製造方法。
JP2000356303A 2000-01-11 2000-11-22 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、 Expired - Fee Related JP4316787B2 (ja)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP2000356303A JP4316787B2 (ja) 2000-01-11 2000-11-22 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、
KR1020010000631A KR20010070442A (ko) 2000-01-11 2001-01-05 에테르 및 아미드 화합물 및 항당뇨병제로서의 그의 제제
GB0100433A GB2359082B (en) 2000-01-11 2001-01-08 Antidiabetic ether and amide compounds and preparation thereof
FR0100207A FR2804681B1 (fr) 2000-01-11 2001-01-09 Compose antidiabetique et procede pour sa production
US09/756,701 US6414001B2 (en) 2000-01-11 2001-01-10 Ether and amide compounds preparation thereof composition containing same and use thereof as antidiadetics
ES200100058A ES2187261B2 (es) 2000-01-11 2001-01-10 Compuestos de eteres y amidas y su preparacion, como agentes anti-diabeticos.
DE10100772A DE10100772B4 (de) 2000-01-11 2001-01-10 Ether- und Amidverbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Antidiabetika
IT2001MI000042A ITMI20010042A1 (it) 2000-01-11 2001-01-11 Composti di eteri e di ammidi e loro preparazione come antidiabetici
CNB011047011A CN1227231C (zh) 2000-01-11 2001-01-11 作为抗糖尿病药的醚和酰胺类化合物及制备方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000006106 2000-01-11
JP2000-6106 2000-01-11
JP2000356303A JP4316787B2 (ja) 2000-01-11 2000-11-22 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、

Publications (3)

Publication Number Publication Date
JP2001261662A JP2001261662A (ja) 2001-09-26
JP2001261662A5 true JP2001261662A5 (ja) 2005-07-28
JP4316787B2 JP4316787B2 (ja) 2009-08-19

Family

ID=26583525

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000356303A Expired - Fee Related JP4316787B2 (ja) 2000-01-11 2000-11-22 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、

Country Status (9)

Country Link
US (1) US6414001B2 (ja)
JP (1) JP4316787B2 (ja)
KR (1) KR20010070442A (ja)
CN (1) CN1227231C (ja)
DE (1) DE10100772B4 (ja)
ES (1) ES2187261B2 (ja)
FR (1) FR2804681B1 (ja)
GB (1) GB2359082B (ja)
IT (1) ITMI20010042A1 (ja)

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SK1872003A3 (en) 2000-08-23 2003-07-01 Lilly Co Eli Oxazolyl-arylpropionic acid derivatives and their use as PPAR agonists
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ES2288982T3 (es) 2000-08-23 2008-02-01 Eli Lilly And Company Derivados de acido oxazolil-ariloxiacetico y su uso como agonistas ppar.
US7009057B2 (en) * 2001-04-26 2006-03-07 Zentiva A.S. Method for obtaining pioglitazone as an antidiabetic agent
US7282501B2 (en) 2001-06-07 2007-10-16 Eli Lilly And Company Modulators of peroxisome proliferator activated receptors (PPAR)
US20030171377A1 (en) * 2001-08-29 2003-09-11 Bigge Christopher Franklin Antidiabetic agents
TWI281916B (en) 2001-10-25 2007-06-01 Lilly Co Eli Antitumor compounds and methods
US6716842B2 (en) 2002-04-05 2004-04-06 Warner-Lambert Company, Llc Antidiabetic agents
US7279576B2 (en) * 2002-12-31 2007-10-09 Deciphera Pharmaceuticals, Llc Anti-cancer medicaments
US20080045706A1 (en) * 2002-12-31 2008-02-21 Flynn Daniel L Anti-inflammatory medicaments
US7144911B2 (en) 2002-12-31 2006-12-05 Deciphera Pharmaceuticals Llc Anti-inflammatory medicaments
US7202257B2 (en) * 2003-12-24 2007-04-10 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
JP2006520755A (ja) 2003-02-14 2006-09-14 イーライ リリー アンド カンパニー Ｐｐａｒモジュレータとしてのスルホンアミド誘導体
US7348453B2 (en) * 2003-09-04 2008-03-25 Mirus Bio Corporation Labile linkage for compound delivery to a cell
JP4175291B2 (ja) * 2004-05-12 2008-11-05 トヨタ自動車株式会社 車両の減速制御装置
DE102004039509B4 (de) * 2004-08-14 2006-09-21 Sanofi-Aventis Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
SI1650186T1 (sl) * 2004-10-22 2008-12-31 Bioprojet Soc Civ Novi derivati dikarboksilne kisline
CN101735048A (zh) * 2008-11-05 2010-06-16 上海慈瑞医药科技有限公司 具胰岛素增敏活性的水杨酸类化合物及其制备方法
SG11201408284VA (en) 2012-05-22 2015-02-27 Xenon Pharmaceuticals Inc N-substituted benzamides and their use in the treatment of pain
WO2014008458A2 (en) * 2012-07-06 2014-01-09 Genentech, Inc. N-substituted benzamides and methods of use thereof
BR112015008987A2 (pt) 2012-10-26 2017-07-04 Merck Sharp & Dohme composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de uma composição farmacêutica
CN112028833B (zh) * 2020-09-25 2022-07-05 西南大学 对氨基水杨酸唑类衍生物及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989008652A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
US5239080A (en) * 1989-02-08 1993-08-24 Takeda Chemical Industries, Ltd. Oxazole compounds and their use as antidiabetic and bone-reduction inhibitory agents
KR930701420A (ko) * 1990-08-23 1993-06-11 알렌 제이. 스피겔 혈당저하제로서의 하이드록시우레아 유도체
TW245716B (ja) * 1992-12-28 1995-04-21 Takeda Pharm Industry Co
TW268952B (ja) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
CN1233241A (zh) * 1996-08-19 1999-10-27 日本烟草产业株式会社 丙酸衍生物及其用途
WO1999046232A1 (fr) * 1998-03-10 1999-09-16 Ono Pharmaceutical Co., Ltd. Derives d'acide carboxylique et medicaments contenant ces derives comme principe actif
EP1212304A2 (en) * 1999-08-27 2002-06-12 Eli Lilly And Company Hypoglycemic sulfonyl pyrazolones and pyrazolines
US6617343B1 (en) * 1999-08-27 2003-09-09 Eli Lilly And Company Hypoglycemic N,N-arylsulfonylglycine compounds

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