JP2001526224A5 - - Google Patents
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- Publication number
- JP2001526224A5 JP2001526224A5 JP2000525105A JP2000525105A JP2001526224A5 JP 2001526224 A5 JP2001526224 A5 JP 2001526224A5 JP 2000525105 A JP2000525105 A JP 2000525105A JP 2000525105 A JP2000525105 A JP 2000525105A JP 2001526224 A5 JP2001526224 A5 JP 2001526224A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cancer
- fpt inhibitor
- substituted
- proliferative disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99602797A | 1997-12-22 | 1997-12-22 | |
| US08/996,027 | 1997-12-22 | ||
| US14352998A | 1998-08-28 | 1998-08-28 | |
| US09/143,529 | 1998-08-28 | ||
| US18196998A | 1998-10-29 | 1998-10-29 | |
| US09/181,969 | 1998-10-29 | ||
| PCT/US1998/026224 WO1999032114A1 (en) | 1997-12-22 | 1998-12-21 | Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001526224A JP2001526224A (ja) | 2001-12-18 |
| JP2001526224A5 true JP2001526224A5 (https=) | 2006-02-09 |
| JP4502503B2 JP4502503B2 (ja) | 2010-07-14 |
Family
ID=27385940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000525105A Expired - Fee Related JP4502503B2 (ja) | 1997-12-22 | 1998-12-21 | 増殖性の疾患を処置するためのベンゾシクロヘプタピリジン化合物および抗腫瘍剤の組合せ |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1041985B1 (https=) |
| JP (1) | JP4502503B2 (https=) |
| KR (1) | KR100700907B1 (https=) |
| CN (1) | CN1129431C (https=) |
| AR (1) | AR017440A1 (https=) |
| AT (1) | ATE317697T1 (https=) |
| AU (1) | AU756762B2 (https=) |
| BR (1) | BR9814419A (https=) |
| CA (1) | CA2315693C (https=) |
| CL (1) | CL2007001889A1 (https=) |
| CO (1) | CO5080764A1 (https=) |
| CZ (1) | CZ298511B6 (https=) |
| DE (1) | DE69833509T2 (https=) |
| DK (1) | DK1041985T3 (https=) |
| ES (1) | ES2255196T3 (https=) |
| HU (1) | HUP0102473A3 (https=) |
| IL (1) | IL136462A0 (https=) |
| MY (1) | MY137303A (https=) |
| NO (1) | NO326832B1 (https=) |
| NZ (1) | NZ504928A (https=) |
| PE (1) | PE20000042A1 (https=) |
| PT (1) | PT1041985E (https=) |
| SK (1) | SK285584B6 (https=) |
| TW (1) | TW581763B (https=) |
| WO (1) | WO1999032114A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787327B1 (fr) * | 1998-12-21 | 2003-01-17 | Aventis Pharma Sa | Compositions contenant des inhibiteurs de farnesyle transferase |
| EP1233787B8 (fr) * | 1999-11-09 | 2005-05-18 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Produit comprenant un inhibiteur de la transduction des signaux des proteines g heterotrimeriques en association avec un autre agent anti-cancereux pour une utilisation therapeutique dans le traitement du cancer |
| AU2292801A (en) * | 1999-12-22 | 2001-07-03 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Compositions and methods for treatment of breast cancer |
| WO2001064196A2 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with vinca alkaloids |
| JP2003525244A (ja) * | 2000-02-29 | 2003-08-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 抗腫瘍性アルキル化剤とのファルネシルタンパク質トランスフェラーゼ阻害剤組み合わせ剤 |
| JP2003525238A (ja) * | 2000-02-29 | 2003-08-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 抗腫瘍性ポドフィロトキシン誘導体とのファルネシルタンパク質トランスフェラーゼ阻害剤組み合わせ剤 |
| CA2397690A1 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives |
| AU2001244167A1 (en) * | 2000-02-29 | 2001-09-12 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives |
| US20030027808A1 (en) * | 2000-02-29 | 2003-02-06 | Palmer Peter Albert | Farnesyl protein transferase inhibitor combinations with platinum compounds |
| TWI310684B (en) | 2000-03-27 | 2009-06-11 | Bristol Myers Squibb Co | Synergistic pharmaceutical kits for treating cancer |
| AU2002236813A1 (en) * | 2001-01-22 | 2002-07-30 | Schering Corporation | Treatment of malaria with farnesyl protein transferase inhibitors |
| DE60230017D1 (de) * | 2001-02-15 | 2009-01-08 | Janssen Pharmaceutica Nv | Farnesyl-protein-transferase hemmer in kombination mit antiöstrogenen |
| WO2003047697A2 (en) * | 2001-11-30 | 2003-06-12 | Schering Corporation | Use of an farsenyl protein tranferase inhibitor in combination with other antineoplastic agents for the manufacture of a medicament against cancer |
| AU2002346644A1 (en) * | 2001-12-03 | 2003-06-17 | Schering Corporation | Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer |
| WO2008022535A1 (fr) * | 2006-08-09 | 2008-02-28 | Tian Jin Tasly Group Co., Ltd. | Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique |
| CN105198758A (zh) * | 2015-09-22 | 2015-12-30 | 湖南大学 | 一种高纯度(z)-他莫昔酚的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| DE69120430D1 (de) * | 1990-12-18 | 1996-07-25 | Wellcome Found | Mittel zur verstaerkung der wirkung von antitumoralen mittel und zur widerstandsbekaempfung von vielfachdrogen |
| JP2767176B2 (ja) * | 1992-12-15 | 1998-06-18 | 大塚製薬株式会社 | 抗癌剤 |
| US5637688A (en) * | 1994-12-13 | 1997-06-10 | Eli Lilly And Company | Process for preparing 1-(2'-deoxy-2'-difluoro-d-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride |
| WO1997005902A1 (fr) * | 1995-08-09 | 1997-02-20 | Banyu Pharmaceutical Co., Ltd. | Composition medicinale |
| SK86198A3 (en) * | 1995-12-22 | 1999-02-11 | Schering Corp | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
| DE69735057T2 (de) * | 1996-03-12 | 2006-08-31 | PG-TXL Co., L.P., Houston | Wasserlösliche paclitaxel-prodrogen |
| JP2000507584A (ja) * | 1996-04-03 | 2000-06-20 | メルク エンド カンパニー インコーポレーテッド | ファルネシル―タンパク質転移酵素の阻害剤 |
| CA2251716A1 (en) * | 1996-04-15 | 1997-10-23 | W. Gillies Mckenna | Sensitization of cells to radiation and chemotherapy |
| EP0952842A2 (en) * | 1996-04-18 | 1999-11-03 | Merck & Co., Inc. | A method of treating cancer |
| JP2000508335A (ja) * | 1996-05-30 | 2000-07-04 | メルク エンド カンパニー インコーポレーテッド | 癌の治療方法 |
| JP2001508326A (ja) * | 1997-01-29 | 2001-06-26 | ピッカー メディカル システムズ リミテッド | 予測的ボーラス追跡 |
| CZ298488B6 (cs) * | 1997-02-18 | 2007-10-17 | Canji, Inc. | Farmaceutický prostredek s obsahem tumor-supresorové nukleové kyseliny |
-
1998
- 1998-12-21 PE PE1998001263A patent/PE20000042A1/es not_active Application Discontinuation
- 1998-12-21 CA CA2315693A patent/CA2315693C/en not_active Expired - Fee Related
- 1998-12-21 AT AT98963829T patent/ATE317697T1/de not_active IP Right Cessation
- 1998-12-21 SK SK898-2000A patent/SK285584B6/sk not_active IP Right Cessation
- 1998-12-21 MY MYPI98005809A patent/MY137303A/en unknown
- 1998-12-21 DK DK98963829T patent/DK1041985T3/da active
- 1998-12-21 AR ARP980106565A patent/AR017440A1/es unknown
- 1998-12-21 CZ CZ20002236A patent/CZ298511B6/cs not_active IP Right Cessation
- 1998-12-21 CO CO98075842A patent/CO5080764A1/es unknown
- 1998-12-21 EP EP98963829A patent/EP1041985B1/en not_active Expired - Lifetime
- 1998-12-21 TW TW087121355A patent/TW581763B/zh not_active IP Right Cessation
- 1998-12-21 WO PCT/US1998/026224 patent/WO1999032114A1/en not_active Ceased
- 1998-12-21 PT PT98963829T patent/PT1041985E/pt unknown
- 1998-12-21 ES ES98963829T patent/ES2255196T3/es not_active Expired - Lifetime
- 1998-12-21 JP JP2000525105A patent/JP4502503B2/ja not_active Expired - Fee Related
- 1998-12-21 HU HU0102473A patent/HUP0102473A3/hu unknown
- 1998-12-21 DE DE69833509T patent/DE69833509T2/de not_active Expired - Lifetime
- 1998-12-21 BR BR9814419-7A patent/BR9814419A/pt not_active Application Discontinuation
- 1998-12-21 KR KR1020007006938A patent/KR100700907B1/ko not_active Expired - Fee Related
- 1998-12-21 IL IL13646298A patent/IL136462A0/xx unknown
- 1998-12-21 NZ NZ504928A patent/NZ504928A/xx unknown
- 1998-12-21 AU AU19072/99A patent/AU756762B2/en not_active Ceased
- 1998-12-21 CN CN98813742A patent/CN1129431C/zh not_active Expired - Fee Related
-
2000
- 2000-06-21 NO NO20003229A patent/NO326832B1/no not_active IP Right Cessation
-
2007
- 2007-06-27 CL CL2007001889A patent/CL2007001889A1/es unknown
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