DK1041985T3 - Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme - Google Patents

Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme

Info

Publication number
DK1041985T3
DK1041985T3 DK98963829T DK98963829T DK1041985T3 DK 1041985 T3 DK1041985 T3 DK 1041985T3 DK 98963829 T DK98963829 T DK 98963829T DK 98963829 T DK98963829 T DK 98963829T DK 1041985 T3 DK1041985 T3 DK 1041985T3
Authority
DK
Denmark
Prior art keywords
prophylactic
disorders
treatment
combination
antineoplastic drugs
Prior art date
Application number
DK98963829T
Other languages
English (en)
Inventor
Ronald J Doll
Ashit Ganguly
David L Cutler
Walter R Bishop
Joseph J Catino
Viyyoor Girijavallabhan
Paul Kirschmeier
Ming Liu
Loretta L Nielsen
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27385940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1041985(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK1041985T3 publication Critical patent/DK1041985T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK98963829T 1997-12-22 1998-12-21 Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme DK1041985T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99602797A 1997-12-22 1997-12-22
US14352998A 1998-08-28 1998-08-28
US18196998A 1998-10-29 1998-10-29

Publications (1)

Publication Number Publication Date
DK1041985T3 true DK1041985T3 (da) 2006-06-19

Family

ID=27385940

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98963829T DK1041985T3 (da) 1997-12-22 1998-12-21 Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme

Country Status (25)

Country Link
EP (1) EP1041985B1 (da)
JP (1) JP4502503B2 (da)
KR (1) KR100700907B1 (da)
CN (1) CN1129431C (da)
AR (1) AR017440A1 (da)
AT (1) ATE317697T1 (da)
AU (1) AU756762B2 (da)
BR (1) BR9814419A (da)
CA (1) CA2315693C (da)
CL (1) CL2007001889A1 (da)
CO (1) CO5080764A1 (da)
CZ (1) CZ298511B6 (da)
DE (1) DE69833509T2 (da)
DK (1) DK1041985T3 (da)
ES (1) ES2255196T3 (da)
HU (1) HUP0102473A3 (da)
IL (1) IL136462A0 (da)
MY (1) MY137303A (da)
NO (1) NO326832B1 (da)
NZ (1) NZ504928A (da)
PE (1) PE20000042A1 (da)
PT (1) PT1041985E (da)
SK (1) SK285584B6 (da)
TW (1) TW581763B (da)
WO (1) WO1999032114A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787327B1 (fr) * 1998-12-21 2003-01-17 Aventis Pharma Sa Compositions contenant des inhibiteurs de farnesyle transferase
DK1233787T3 (da) * 1999-11-09 2005-08-15 Sod Conseils Rech Applic Produkt, der inhiberer signaltransduktion fra heterotrimere G-proteiner, kombineret med et andet cancerbekæmpende middel til terapeutisk anvendelse i cancerbehandlingen
AU2292801A (en) * 1999-12-22 2001-07-03 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Compositions and methods for treatment of breast cancer
CA2397690A1 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives
US20030078281A1 (en) * 2000-02-29 2003-04-24 Rybak Mary Ellen Margaret Farnesyl protein transferase inhibitor combinations with anti-tumor alkylating agents
CA2397475A1 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with vinca alkaloids
EP1267871A2 (en) * 2000-02-29 2003-01-02 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives
EP1267872A2 (en) * 2000-02-29 2003-01-02 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
JP2003525246A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 白金化合物とのファルネシルタンパク質トランスフェラーゼ阻害剤の組み合わせ剤
TWI310684B (en) 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
WO2002056884A2 (en) * 2001-01-22 2002-07-25 Schering Corporation Treatment of malaria with farnesyl protein transferase inhibitors
US20040110769A1 (en) * 2001-02-15 2004-06-10 End David William Farnesyl protein transferase inhibitor combinations with antiestrogen agents
US20030185831A1 (en) * 2001-11-30 2003-10-02 Schering Corporation Methods of treating cancer using an FPT inhibitor and antineoplastic
CA2468996A1 (en) * 2001-12-03 2003-06-12 Schering Corporation Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer
WO2008022535A1 (fr) * 2006-08-09 2008-02-28 Tian Jin Tasly Group Co., Ltd. Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique
CN105198758A (zh) * 2015-09-22 2015-12-30 湖南大学 一种高纯度(z)-他莫昔酚的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
EP0563134B1 (en) * 1990-12-18 1996-06-19 The Wellcome Foundation Limited Agents for potentiating the effects of antitumor agents and combating multiple drug resistance
JP2767176B2 (ja) * 1992-12-15 1998-06-18 大塚製薬株式会社 抗癌剤
US5637688A (en) * 1994-12-13 1997-06-10 Eli Lilly And Company Process for preparing 1-(2'-deoxy-2'-difluoro-d-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride
DE69635114T2 (de) * 1995-08-09 2006-03-02 Banyu Pharmaceutical Co., Ltd. Proteinfarnesyltransferase-inhibitoren in kombination mit hmgcoa-reduktase-inhibitoren zur behandlung von aids
TW350844B (en) * 1995-12-22 1999-01-21 Schering Corp Tricyclic amides useful to inhibition of G-protein function and for treatment of proliferative diseases
AU735900B2 (en) * 1996-03-12 2001-07-19 Pg-Txl Company, L.P. Water soluble paclitaxel prodrugs
CA2250143A1 (en) * 1996-04-03 1997-10-09 Jeffrey Bergman Inhibitors of farnesyl-protein transferase
EP0910385A4 (en) * 1996-04-15 1999-12-22 Univ Pennsylvania SENSITIZATION OF CELLS FOR RADIATION AND CHEMOTHERAPY
EP0952842A2 (en) * 1996-04-18 1999-11-03 Merck & Co., Inc. A method of treating cancer
WO1997045412A1 (en) * 1996-05-30 1997-12-04 Merck & Co., Inc. A method of treating cancer
JP2001508326A (ja) * 1997-01-29 2001-06-26 ピッカー メディカル システムズ リミテッド 予測的ボーラス追跡
ES2287974T3 (es) * 1997-02-18 2007-12-16 Canji, Inc. Terapia genica supresora de tumor y quimioterapia combinadas en el tratamiento neoplasmas.

Also Published As

Publication number Publication date
CZ20002236A3 (cs) 2001-04-11
ATE317697T1 (de) 2006-03-15
AU1907299A (en) 1999-07-12
TW581763B (en) 2004-04-01
SK8982000A3 (en) 2001-04-09
NO326832B1 (no) 2009-02-23
MY137303A (en) 2009-01-30
CL2007001889A1 (es) 2008-01-11
NO20003229D0 (no) 2000-06-21
JP2001526224A (ja) 2001-12-18
AR017440A1 (es) 2001-09-05
CA2315693C (en) 2010-11-30
KR100700907B1 (ko) 2007-03-29
HUP0102473A3 (en) 2003-07-28
IL136462A0 (en) 2001-06-14
EP1041985A1 (en) 2000-10-11
EP1041985B1 (en) 2006-02-15
HUP0102473A2 (hu) 2002-01-28
PE20000042A1 (es) 2000-02-17
ES2255196T3 (es) 2006-06-16
DE69833509T2 (de) 2006-10-26
SK285584B6 (sk) 2007-04-05
CN1129431C (zh) 2003-12-03
CZ298511B6 (cs) 2007-10-24
JP4502503B2 (ja) 2010-07-14
CO5080764A1 (es) 2001-09-25
DE69833509D1 (de) 2006-04-20
NO20003229L (no) 2000-08-22
BR9814419A (pt) 2000-10-10
CA2315693A1 (en) 1999-07-01
AU756762B2 (en) 2003-01-23
WO1999032114A1 (en) 1999-07-01
KR20010033452A (ko) 2001-04-25
NZ504928A (en) 2004-12-24
PT1041985E (pt) 2006-07-31
CN1284875A (zh) 2001-02-21

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