NO983784D0 - FremgangsmÕter for fremstilling av bifenyl-isoksasolsulfonamider - Google Patents

FremgangsmÕter for fremstilling av bifenyl-isoksasolsulfonamider

Info

Publication number
NO983784D0
NO983784D0 NO983784A NO983784A NO983784D0 NO 983784 D0 NO983784 D0 NO 983784D0 NO 983784 A NO983784 A NO 983784A NO 983784 A NO983784 A NO 983784A NO 983784 D0 NO983784 D0 NO 983784D0
Authority
NO
Norway
Prior art keywords
biphenyl
processes
preparation
isoxazole sulfonamides
sulfonamides
Prior art date
Application number
NO983784A
Other languages
English (en)
Other versions
NO311430B1 (no
NO983784L (no
Inventor
Richard P Polniaszek
Xuebao Wang
Jeffrey S Depue
Chennagiri Pandit
Kumar G Gadamasetti
Yadagiri Pendri
Eduardo J Martinez
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/786,523 external-priority patent/US5856507A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO983784D0 publication Critical patent/NO983784D0/no
Publication of NO983784L publication Critical patent/NO983784L/no
Publication of NO311430B1 publication Critical patent/NO311430B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
NO19983784A 1996-02-20 1998-08-19 Fremgangsmåte for fremstilling av bifenyl- isoksasolsulfonamider og mellomprodukter i denne NO311430B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1197496P 1996-02-20 1996-02-20
US08/786,523 US5856507A (en) 1997-01-21 1997-01-21 Methods for the preparation of biphenyl isoxazole sulfonamides
PCT/US1997/002917 WO1997029747A1 (en) 1996-02-20 1997-02-19 Methods for the preparation of biphenyl isoxazole sulfonamides

Publications (3)

Publication Number Publication Date
NO983784D0 true NO983784D0 (no) 1998-08-19
NO983784L NO983784L (no) 1998-08-19
NO311430B1 NO311430B1 (no) 2001-11-26

Family

ID=26682999

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19983784A NO311430B1 (no) 1996-02-20 1998-08-19 Fremgangsmåte for fremstilling av bifenyl- isoksasolsulfonamider og mellomprodukter i denne

Country Status (15)

Country Link
US (1) US6515136B1 (no)
EP (1) EP0904077A4 (no)
JP (1) JP2001523218A (no)
KR (1) KR19990087063A (no)
CN (1) CN1211183A (no)
AU (1) AU717230B2 (no)
BR (1) BR9708151A (no)
CZ (1) CZ263098A3 (no)
HU (1) HUP0002351A3 (no)
IL (1) IL124542A (no)
NO (1) NO311430B1 (no)
NZ (1) NZ330464A (no)
PL (1) PL328571A1 (no)
SG (3) SG87053A1 (no)
WO (1) WO1997029747A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846990A (en) * 1995-07-24 1998-12-08 Bristol-Myers Squibb Co. Substituted biphenyl isoxazole sulfonamides
CN1100047C (zh) * 1998-04-28 2003-01-29 中国人民解放军空军总医院 N3－(5－甲基异噁唑)基－3,4－二羟基肉桂酰胺及其制法
DE69940063D1 (de) 1998-07-06 2009-01-22 Bristol Myers Squibb Co Biphenylsulfonamide als zweifach aktive rezeptor antagonisten von angiotensin und endothelin
DE19858593A1 (de) 1998-12-18 2000-06-21 Merck Patent Gmbh Sulfonyloxazolamine als therapeutische Wirkstoffe
WO2000056685A1 (en) 1999-03-19 2000-09-28 Bristol-Myers Squibb Company Methods for the preparation of biphenyl isoxazole sulfonamides
US6639082B2 (en) * 2000-10-17 2003-10-28 Bristol-Myers Squibb Company Methods for the preparation of biphenyl isoxazole sulfonamides
US20050203189A1 (en) * 2002-01-25 2005-09-15 Noriyuki Miyata Remedies for chronic kidney diseases
CN114262279B (zh) * 2021-12-30 2022-12-16 上海汇禾医疗科技有限公司 一种x射线可显影分子、栓塞微球及其制备方法

Family Cites Families (46)

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GB804036A (en) 1956-03-02 1958-11-05 Hoffmann La Roche A process for the manufacture of a sulphanilamide of the isoxazole series
DE1059459B (de) 1956-09-04 1959-06-18 Shionogi & Co Verfahren zur Herstellung des therapeutisch wertvollen 3-Sulfanilamido-5-methylisoxazols
CH364506A (de) 1956-09-04 1962-09-30 Shionogi & Co Verfahren zur Herstellung des therapeutisch wirksamen 3-Sulfanilamido-5-methyl-isoxazols
US2888455A (en) * 1956-09-04 1959-05-26 Shionogi & Co New sulfonamide and process for producing the same
GB897440A (en) 1960-02-08 1962-05-30 Shionogi & Co Improvements in or relating to sulfonamides
GB1473433A (no) 1975-10-09 1977-05-11 Banyu Pharmaceutical Co Ltd Hi
US4415496A (en) * 1981-03-23 1983-11-15 Merck & Co., Inc. Bicyclic lactams
EP0076072B1 (en) 1981-09-24 1987-05-13 BEECHAM - WUELFING GmbH & Co. KG Sulphonamides
US4661479A (en) * 1982-02-19 1987-04-28 Merck And Co., Inc. Bicyclic lactams as antihypertensives
EP0194548A3 (de) 1985-03-12 1988-08-17 Dr. Karl Thomae GmbH Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5464853A (en) 1993-05-20 1995-11-07 Immunopharmaceutics, Inc. N-(5-isoxazolyl)biphenylsulfonamides, N-(3-isoxazolyl)biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US5594021A (en) 1993-05-20 1997-01-14 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl sulfonamides and derivatives thereof that modulate the activity of endothelin
US5514691A (en) 1993-05-20 1996-05-07 Immunopharmaceutics, Inc. N-(4-halo-isoxazolyl)-sulfonamides and derivatives thereof that modulate the activity of endothelin
US5591761A (en) 1993-05-20 1997-01-07 Texas Biotechnology Corporation Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US5571821A (en) 1993-05-20 1996-11-05 Texas Biotechnology Corporation Sulfonamides and derivatives thereof that modulate the activity of endothelin
CA2005741C (en) 1988-12-26 1998-06-02 Hiroyoshi Hidaka Quinoline sulfonoamino compounds having vessel smooth muscle relaxation activity
US5082838A (en) 1989-06-21 1992-01-21 Takeda Chemical Industries, Ltd. Sulfur-containing fused pyrimidine derivatives, their production and use
DE122010000024I1 (de) 1990-02-19 2010-07-08 Novartis Ag Acylverbindungen
CA2079343A1 (en) 1990-03-30 1991-10-01 Eric E. Allen Substituted pyrazoles, isoxazoles and isothiazoles
US5236928A (en) 1991-03-19 1993-08-17 Merck & Co., Inc. Imidazole derivatives bearing acidic functional groups at the 5-position, their compositions and methods of use as angiotensin II antagonists
TW270116B (no) 1991-04-25 1996-02-11 Hoffmann La Roche
RU2086544C1 (ru) 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
JP2667294B2 (ja) 1991-11-05 1997-10-27 スミスクライン・ビーチャム・コーポレイション エンドセリン受容体拮抗剤
SE9103397D0 (sv) 1991-11-18 1991-11-18 Kabi Pharmacia Ab Nya substituerade salicylsyror
US5378715A (en) 1992-02-24 1995-01-03 Bristol-Myers Squibb Co. Sulfonamide endothelin antagonists
TW224462B (no) 1992-02-24 1994-06-01 Squibb & Sons Inc
TW215434B (no) 1992-03-07 1993-11-01 Hoechst Ag
NZ247440A (en) * 1992-05-06 1995-04-27 Squibb & Sons Inc Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof
US5514696A (en) * 1992-05-06 1996-05-07 Bristol-Myers Squibb Co. Phenyl sulfonamide endothelin antagonists
WO1993023404A1 (en) 1992-05-19 1993-11-25 Immunopharmaceutics, Inc. Compounds that modulate endothelin activity
TW287160B (no) 1992-12-10 1996-10-01 Hoffmann La Roche
ATE189217T1 (de) 1993-03-19 2000-02-15 Merck & Co Inc Phenoxyphenylessigsäurederivate
FI941826A (fi) 1993-04-21 1994-10-22 Takeda Chemical Industries Ltd Menetelmät ja koostumukset elimen hypofunktion ennaltaehkäisemiseksi ja/tai terapeuttiseksi hoitamiseksi
TW394761B (en) 1993-06-28 2000-06-21 Hoffmann La Roche Novel Sulfonylamino Pyrimidines
PT634175E (pt) 1993-07-15 2001-06-29 Hoffmann La Roche Combinacao farmaceutica que contem um inibidor do sistema renina-angiotensina e o antagonista de endotelina
US5965732A (en) 1993-08-30 1999-10-12 Bristol-Myers Squibb Co. Sulfonamide endothelin antagonists
GB9504854D0 (en) 1994-03-31 1995-04-26 Zeneca Ltd Nitrogen derivatives
GB9409618D0 (en) 1994-05-13 1994-07-06 Zeneca Ltd Pyridine derivatives
US5612359A (en) * 1994-08-26 1997-03-18 Bristol-Myers Squibb Company Substituted biphenyl isoxazole sulfonamides
IL116916A (en) * 1995-02-06 2000-09-28 Bristol Myers Squibb Co Substituted biphenyl sulfonamide derivatives and pharmaceutical compositions containing the same
DE19509950A1 (de) 1995-03-18 1996-09-19 Merck Patent Gmbh Endothelin-Rezeptor-Antagonisten
NZ306734A (no) 1995-04-04 2000-01-28 Texas Biotechnology Corp
UA58494C2 (uk) 1995-06-07 2003-08-15 Зенека Лімітед Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну
GB9512697D0 (en) 1995-06-22 1995-08-23 Zeneca Ltd Heterocyclic compounds
US5846990A (en) * 1995-07-24 1998-12-08 Bristol-Myers Squibb Co. Substituted biphenyl isoxazole sulfonamides
US5580894A (en) * 1996-01-11 1996-12-03 Howard University Isoxazolyl enaminones

Also Published As

Publication number Publication date
BR9708151A (pt) 1999-07-27
IL124542A (en) 2003-07-06
SG87051A1 (en) 2002-03-19
HUP0002351A2 (hu) 2001-09-28
HUP0002351A3 (en) 2001-10-29
CN1211183A (zh) 1999-03-17
SG87052A1 (en) 2002-03-19
IL124542A0 (en) 1998-12-06
JP2001523218A (ja) 2001-11-20
US6515136B1 (en) 2003-02-04
SG87053A1 (en) 2002-03-19
NZ330464A (en) 2000-04-28
EP0904077A2 (en) 1999-03-31
CZ263098A3 (cs) 1999-05-12
NO311430B1 (no) 2001-11-26
KR19990087063A (ko) 1999-12-15
NO983784L (no) 1998-08-19
AU1973797A (en) 1997-09-02
AU717230B2 (en) 2000-03-23
EP0904077A4 (en) 1999-12-22
PL328571A1 (en) 1999-02-01
WO1997029747A1 (en) 1997-08-21

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